Statistics and landscape

The Statistical results for RNA editing related cancer mechanisms
The enrichment results of enriched editing regions
The distributions of editing enriched regions in genomic locations

More EERs located in non-coding region and Alu repeats.

Comparisons of the length of Genes/ Introns/ Exons/ UTR3 with EERs and without EERs

Longer Genes/ Introns/ Exons/ UTR3 are more likely to be edited.

dsRNA structure of EER surrounding region

Editing events are prone to occur in dsRNA structure.

Editing in different clinical conditions


Editing with immune infiltration

(a)EERs are positively associated with the cell fraction of activated immune memory cells (B_cells_memory and T_cells_CD4_memory_activated).

(b)EERs are negatively associated with the cell fraction of immune naive cells (B_cells_naive and T_cells_CD4_naive)

(c)EERs are positively associated with the cell fraction of activated immune cells (Dendritic_cells_activated, Mast_cells_activated, NK_cells_activated and T_cells_CD4_memory_activated).

(d)Significantly positively associated between EERs and immune cells: Dendritic_cells_activated, Macrophages_M1, T_cells_CD4_memory_activated, T_cells_CD8, T_cells_gamma_delta.

Editing with hallmark gene set