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4. Enriched editing regions and immune related splicing for MED13


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark gene sets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr17:61998582-62001083:-
ESCAEERIRENSG00000198911.7chr2241898648:41898781:41899236:41899553-0.28724.2157e-024.3857e-07-0.4352imageNNSREBF2Macrophages_M2GSVA_HALLMARK_HYPOXIA
chr17:61998582-62001083:-
ESCAEERIRENSG00000111725.6chr12119671494:119671668:119672300:119672427-0.36413.0196e-031.3948e-06-0.4115imageNNPRKAB1T_cells_CD4_memory_restingGSVA_HALLMARK_MTORC1_SIGNALING
chr17:61998582-62001083:-
ESCAEERIRENSG00000116350.11chr129165889:29166912:29168502:29168638-0.40282.2269e-034.9247e-08-0.4287imageNNNAMacrophages_M2GSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING
ENSG00000108510.8,MED13
ESCAEAGIRENSG00000174720.11chr4112646790:112647127:112647198:112647449-0.42827.0891e-041.6496e-08-0.4342imageNACIN1;ADAR;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;METTL3;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RBFOX2;RBM10;RBM22;RBM47;RNF219;SAFB2;SF3A3;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZFP36;ZNF184NADendritic_cells_activatedGSVA_HALLMARK_MTORC1_SIGNALING
chr17:61998582-62001083:-
ESCAEERIRENSG00000166888.6chr1257102828:57102921:57104326:57104586-0.37527.1680e-038.7229e-09-0.4444imageNNSTAT6T_cells_regulatory_(Tregs)GSVA_HALLMARK_MTORC1_SIGNALING
chr17:61998582-62001083:-
ESCAEERIRENSG00000140463.9chr1572735076:72735966:72736761:72736963-0.43634.3808e-043.0525e-07-0.4035imageNNBBS4Macrophages_M2GSVA_HALLMARK_GLYCOLYSIS
ENSG00000108510.8,MED13
ESCAEAGIRENSG00000188811.8chr1339039135:39039711:39044089:39044181-0.36095.3951e-031.7933e-07-0.4296imageNAIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL3;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM27;RBM47;RNF219;SAFB2;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;ZC3H7B;ZNF184NAB_cells_naiveGSVA_HALLMARK_GLYCOLYSIS
chr17:61998582-62001083:-
ESCAEERIRENSG00000089053.8chr12121309700:121309863:121309969:121310011-0.42418.3459e-041.0238e-09-0.4712imageNNNAT_cells_CD4_memory_restingGSVA_HALLMARK_MTORC1_SIGNALING
chr17:61998582-62001083:-
ESCAEERIRENSG00000204859.7chr16580540:6582299:6585918:6586030-0.44633.0343e-045.5477e-08-0.4233imageNNNAT_cells_CD4_memory_restingGSVA_HALLMARK_GLYCOLYSIS
chr17:61998582-62001083:-
ESCAEERIRENSG00000188811.8chr1339039135:39039711:39044089:39044181-0.39071.2840e-032.9071e-08-0.4567imageNNNAB_cells_naiveGSVA_HALLMARK_GLYCOLYSIS
chr17:61998582-62001083:-
ESCAEERIRENSG00000189180.11chr1038012297:38012350:38016870:38017011-0.45951.4878e-047.1254e-08-0.4201imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_GLYCOLYSIS
ENSG00000108510.8,MED13
ESCAEAGIRENSG00000140463.9chr1572735076:72735966:72736761:72736963-0.41231.4052e-031.9635e-07-0.4070imageNACIN1;ADAR;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI1;MSI2;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SRSF1;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;ZC3H7B;ZNF184BBS4Macrophages_M2GSVA_HALLMARK_GLYCOLYSIS
chr17:61998582-62001083:-
ESCAEERIRENSG00000175390.8chr117991780:7991971:7992083:7992163-0.28744.0257e-022.2458e-06-0.4196imageNNNAB_cells_naiveGSVA_HALLMARK_MTORC1_SIGNALING
chr17:61998582-62001083:-
ESCAEERIRENSG00000115216.9chr227435722:27435746:27436752:27436836-0.35431.0188e-025.1070e-07-0.4094imageNNNAT_cells_CD4_memory_restingGSVA_HALLMARK_ESTROGEN_RESPONSE_LATE
chr17:61998582-62001083:-
ESCAEERIRENSG00000174720.11chr4112646790:112647127:112647198:112647449-0.43226.0540e-044.6295e-08-0.4242imageNNNADendritic_cells_activatedGSVA_HALLMARK_MTORC1_SIGNALING
chr17:61998582-62001083:-
ESCAEERIRENSG00000103275.14chr161312184:1312603:1314019:1314032-0.40769.4624e-042.5638e-07-0.4136imageNNNAT_cells_CD4_memory_restingGSVA_HALLMARK_MTORC1_SIGNALING
ENSG00000108510.8,MED13
ESCAEAGIRENSG00000174720.11chr4112646790:112646955:112647033:112647127-0.41521.5077e-037.7496e-08-0.4153imageNACIN1;ADAR;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;METTL3;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RBFOX2;RBM10;RBM22;RBM47;RNF219;SAFB2;SF3A3;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZFP36;ZNF184NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000108510.8,MED13
ESCAEAGIRENSG00000116350.11chr129165889:29166912:29168502:29168638-0.36691.0526e-022.7588e-07-0.4036imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI1;MSI2;NCBP3;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RTCB;SAFB2;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;ZC3H7B;ZFP36;ZNF184NAMacrophages_M2GSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING