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4. Enriched editing regions and immune related splicing for HAVCR2


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark gene sets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000135077.7,HAVCR2
GBMEAGIRENSG00000102054.13chrX16852045:16852122:16852415:16852517-0.28862.4721e-025.6786e-06-0.4090imageNACIN1;ADAR;ALYREF;BCCIP;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28B;LSM11;MBNL2;MOV10;MSI2;NOP56;NOP58;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM47;RNF219;SAFB2;SLTM;SND1;SRSF1;SRSF10;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;ZC3H7B;ZNF184NAMonocytesGSVA_HALLMARK_PEROXISOME
chr5:157133784-157134472:-
GBMEERIRENSG00000102054.13chrX16852045:16852122:16852415:16852517-0.27943.0064e-028.9270e-06-0.4010imageNNNAMonocytesGSVA_HALLMARK_PEROXISOME
ENSG00000135077.7,HAVCR2
THYMEAGESENSG00000214022.7chr7150368789:150368941:150369670:150370884:150371227:150374044-0.30022.5985e-022.7752e-05-0.4309imageNACIN1;ALYREF;BCCIP;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DICER1;EIF4A3;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28B;LSM11;MBNL2;MOV10;MSI2;NOP56;NOP58;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM47;RNF219;SAFB2;SLTM;SND1;SRSF1;SRSF10;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TRA2A;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;ZC3H7B;ZNF184NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_G2M_CHECKPOINT
ENSG00000135077.7,HAVCR2
THYMEAGIRENSG00000143851.11chr1202147014:202147575:202148553:2021486990.28841.5905e-021.2605e-050.4014imageNADAR;CPSF6;CSTF2T;DDX3X;DGCR8;DKC1;EIF4G2;ELAVL1;FAM120A;FMR1;FUS;FXR1;GTF2F1;HNRNPA1;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHSRP;LIN28B;LSM11;MSI2;PRPF8;PTBP1;SAFB2;SLTM;SND1;SRSF1;TAF15;TARDBP;TRA2A;U2AF1;U2AF2;XRN2PTPN7NK_cells_activatedGSVA_HALLMARK_PROTEIN_SECRETION
chr5:157133784-157134472:-
THYMEERA3ENSG00000205531.8chr112951258:2951295:2944436:2945643:2944436:29492640.34361.6990e-021.1317e-050.4017imageNNNAT_cells_CD8GSVA_HALLMARK_PROTEIN_SECRETION
ENSG00000135077.7,HAVCR2
THYMEAGIRENSG00000138030.8chr227098922:27099284:27099419:270994680.28951.5389e-027.9528e-070.5031imageNBCCIP;BUD13;CNBP;CSTF2T;DDX3X;DGCR8;DICER1;DKC1;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FUS;GTF2F1;HNRNPA1;HNRNPC;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHDRBS2;LARP4B;LIN28;LIN28B;LSM11;MOV10;NOP56;NOP58;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;SAFB2;SLTM;SND1;SRSF1;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TRA2A;U2AF1;U2AF2;UPF1;XRN2;ZNF184NADendritic_cells_activatedGSVA_HALLMARK_HYPOXIA
chr5:157133784-157134472:-
THYMEERA3ENSG00000213923.6chr2238298785:38298852:38296205:38296686:38296205:38297155-0.28552.2544e-027.5109e-05-0.4279imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_PROTEIN_SECRETION
chr5:157133784-157134472:-
THYMEERESENSG00000214022.7chr7150368789:150368941:150369670:150370884:150371227:150374044-0.30212.3896e-023.2329e-05-0.4277imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_G2M_CHECKPOINT
ENSG00000135077.7,HAVCR2
THYMEAGA3ENSG00000213923.6chr2238298785:38298852:38296205:38296686:38296205:38297155-0.26564.5264e-021.1386e-04-0.4181imageNACIN1;ADAR;ALYREF;BCCIP;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPM;HNRNPU;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28B;LSM11;MBNL2;MOV10;MSI2;NOP56;NOP58;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RNF219;SLTM;SND1;SRSF1;SRSF10;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TRA2A;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;ZC3H7B;ZFP36;ZNF184NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_PROTEIN_SECRETION
chr5:157133784-157134472:-
THYMEERIRENSG00000138030.8chr227098922:27099284:27099419:270994680.28441.8464e-025.3206e-070.5125imageNNNADendritic_cells_activatedGSVA_HALLMARK_HYPOXIA
chr5:157133784-157134472:-
UCSEERESENSG00000196776.10chr3108047137:108047292:108051938:108051970:108057476:108057533-0.74264.4237e-028.7359e-07-0.6420imageNNCD47GSVA_HALLMARK_SPERMATOGENESIS