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4. Enriched editing regions and immune related splicing for CHTOP


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark gene sets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr1:153638972-153640769:+
ESCAEERIRENSG00000116396.9chr1110219715:110226178:110232910:110234044-0.32991.2948e-027.4781e-06-0.4333imageNACIN1;CNBP;CSTF2T;DGCR8;EIF4A3;ELAVL1;FBL;FMR1;FUS;FXR2;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;IGF2BP1;IGF2BP2;ILF3;LIN28;LIN28A;LIN28B;MOV10;MSI2;NOP56;NOP58;PTBP1;RBM10;TAF15;TARDBP;U2AF2;UPF1;XRN2;YTHDC1;ZC3H7B;ZNF184NAT_cells_CD4_memory_restingGSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:153638972-153640769:+
ESCAEERIRENSG00000198901.9chr1590966039:90969120:90969446:90969623-0.39118.6978e-031.9484e-06-0.4155imageNACIN1;CNBP;CSTF2T;DDX3X;DDX54;DGCR8;EIF4A3;ELAVL1;FAM120A;FBL;FKBP4;FMR1;FUS;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LARP4B;LIN28;LIN28A;LIN28B;MOV10;MSI2;NOP56;NOP58;PRPF8;PTBP1;RBM10;RBM5;SBDS;SF3B4;SMNDC1;SND1;SRSF10;SRSF7;SRSF9;TAF15;TARDBP;TNRC6A;U2AF2;UPF1;XRN2;YTHDC1;YWHAG;ZC3H7B;ZNF184PRC1T_cells_CD4_memory_restingGSVA_HALLMARK_MTORC1_SIGNALING
chr1:153638972-153640769:+
ESCAEERIRENSG00000104613.7chr819845703:19849239:19851648:19851674-0.33461.3606e-022.0928e-06-0.4421imageNACIN1;BCCIP;CNBP;CSTF2T;DDX3X;DDX54;DGCR8;EIF4A3;ELAVL1;FAM120A;FBL;FKBP4;FMR1;FUS;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LARP4B;LIN28;LIN28A;LIN28B;MOV10;MSI2;NOP56;NOP58;PRPF8;PTBP1;RBM10;RBM5;SF3B4;SMNDC1;SND1;SRSF10;SRSF7;SRSF9;TAF15;TARDBP;TNRC6A;U2AF2;UPF1;XRN2;YTHDC1;YWHAG;ZC3H7B;ZNF184NAT_cells_gamma_deltaGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING
chr1:153638972-153640769:+
ESCAEERIRENSG00000163636.6chr364022317:64022523:64022642:64022801-0.34292.1259e-025.2138e-06-0.4138imageNACIN1;BCCIP;CNBP;CSTF2T;DDX3X;DDX54;DGCR8;EIF4A3;ELAVL1;FAM120A;FBL;FKBP4;FMR1;FUS;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LARP4B;LIN28;LIN28A;LIN28B;MOV10;MSI2;NOP56;NOP58;PRPF8;PTBP1;RBM10;SBDS;SF3B4;SMNDC1;SND1;SRSF10;SRSF7;SRSF9;TAF15;TARDBP;TNRC6A;U2AF2;UPF1;XRN2;YTHDC1;YWHAG;ZC3H7B;ZNF184PSMD6T_cells_CD4_memory_restingGSVA_HALLMARK_MTORC1_SIGNALING
ENSG00000160679.11,CHTOP
ESCAEAGIRENSG00000116396.9chr1110219715:110226178:110232910:110234044-0.31092.9604e-021.4824e-05-0.4184imageNACIN1;ADAR;AIFM1;ALYREF;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DGCR8;DHX9;DICER1;DKC1;EIF4A3;ELAVL1;ELAVL3;FBL;FMR1;FUS;FXR2;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;IGF2BP1;IGF2BP2;ILF3;KHDRBS2;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PTBP1;RANGAP1;RBFOX2;RBM10;RC3H1;RNF219;SRSF1;SRSF3;TAF15;TARDBP;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;ZC3H7B;ZNF184NAT_cells_CD4_memory_restingGSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
ENSG00000160679.11,CHTOP
ESCAEAGIRENSG00000104613.7chr819845703:19849239:19851648:19851674-0.32162.4748e-023.4059e-06-0.4319imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM5;RNF219;RTCB;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAT_cells_gamma_deltaGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING
chr1:153638972-153640769:+
ESCAEERIRENSG00000175866.11chr1781110913:81110955:81115769:81115817-0.31923.9132e-022.9462e-05-0.4011imageNACIN1;BCCIP;CNBP;CSTF2T;DDX3X;DDX54;DGCR8;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LARP4B;LIN28;LIN28B;MOV10;MSI2;NOP56;NOP58;PRPF8;PTBP1;RBM10;RBM5;SF3B4;SMNDC1;SND1;SRSF10;SRSF7;SRSF9;TAF15;TARDBP;TNRC6A;U2AF2;UPF1;XRN2;YTHDC1;YWHAG;ZNF184NAT_cells_CD4_memory_restingGSVA_HALLMARK_MTORC1_SIGNALING
chr1:153638972-153640769:+
ESCAEERIRENSG00000145919.6chr5173609567:173609670:173613130:173613255-0.32522.6640e-022.6653e-06-0.4270imageNBCCIP;CNBP;CSTF2T;DDX3X;DDX54;DGCR8;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LARP4B;LIN28;LIN28A;LIN28B;MOV10;MSI2;NOP56;NOP58;PRPF8;PTBP1;RBM10;RBM5;SF3B4;SMNDC1;SND1;SRSF10;SRSF7;SRSF9;TAF15;TARDBP;TNRC6A;U2AF2;UPF1;XRN2;YTHDC1;ZC3H7B;ZNF184NAB_cells_naiveGSVA_HALLMARK_MYC_TARGETS_V1
chr1:153638972-153640769:+
ESCAEERIRENSG00000183010.12chr1781936735:81936861:81937179:81937239-0.30514.8719e-027.1179e-06-0.4263imageNACIN1;BCCIP;CNBP;CSTF2T;DDX3X;DDX54;DGCR8;EIF4A3;ELAVL1;FAM120A;FBL;FKBP4;FMR1;FUS;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LARP4B;LIN28;LIN28A;LIN28B;MOV10;MSI2;NOP56;NOP58;PRPF8;PTBP1;RBM10;SBDS;SF3B4;SMNDC1;SND1;SRSF7;SRSF9;TAF15;TARDBP;TNRC6A;U2AF2;UPF1;XRN2;YTHDC1;YWHAG;ZNF184NAT_cells_CD4_memory_restingGSVA_HALLMARK_DNA_REPAIR
ENSG00000160679.11,CHTOP
ESCAEAGIRENSG00000163636.6chr364022317:64022523:64022642:64022801-0.33503.1001e-025.1707e-06-0.4140imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FKBP4;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NCBP3;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YWHAG;ZC3H7B;ZNF184PSMD6T_cells_CD4_memory_restingGSVA_HALLMARK_MTORC1_SIGNALING