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4. Enriched editing regions and immune related splicing for LSM14A


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark gene sets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr19:34201363-34207802:+
ESCAEERIRENSG00000002016.12chr12929763:929886:930050:930144-0.34082.8788e-021.3089e-05-0.4131imageNCNBP;DHX9;DKC1;ELAVL1;FBL;FUS;HNRNPC;HNRNPK;HNRNPL;IGF2BP2;NOP56;NOP58;PTBP1;RBFOX2;TAF15;TARDBPNAMacrophages_M2GSVA_HALLMARK_GLYCOLYSIS
ENSG00000257103.7,LSM14A
ESCAEAGIRENSG00000047346.8chr1552584742:52584944:52587055:52587219-0.30413.3308e-029.6593e-06-0.4285imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM47;RBM5;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;ZNF184NANK_cells_activatedGSVA_HALLMARK_GLYCOLYSIS
chr19:34201363-34207802:+
ESCAEERIRENSG00000128833.8chr1552246916:52247014:52247457:52247522-0.31623.1733e-023.8697e-05-0.4031imageNCNBP;DHX9;DKC1;ELAVL1;FBL;FUS;HNRNPC;HNRNPK;HNRNPL;IGF2BP2;NOP56;NOP58;PTBP1;RBFOX2;TAF15;TARDBPNAT_cells_CD4_naiveGSVA_HALLMARK_ADIPOGENESIS