CAeditome Logo

Home

Download

Statistics

Landscape

Help

Contact
Center for Computational Systems Medicine

Back

4. Enriched editing regions and immune related splicing for SPTLC1


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark gene sets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000090054.12,SPTLC1
ESCAEAGA3ENSG00000167658.11chr193979328:3979436:3977891:3978007:3977891:3978091-0.22763.4512e-022.4822e-05-0.4161imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM6;RC3H1;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NA
ENSG00000090054.12,SPTLC1
GBMEAGIRENSG00000102144.9chrX78124873:78125011:78125326:78125425-0.12062.6136e-021.7298e-06-0.4190imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;KHSRP;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM6;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAEosinophils
chr9:92078561-92079375:-
GBMEERIRENSG00000102144.9chrX78124873:78125011:78125326:78125425-0.12052.2473e-021.8387e-06-0.4180imageNELAVL1;MSI1NAEosinophils
chr9:92078561-92079375:-
TGCTEERESENSG00000029725.12chr175354400:5354490:5356507:5356573:5361207:53614380.34321.1165e-023.2052e-050.4012imageNELAVL1;MSI1RABEP1B_cells_naiveGSVA_HALLMARK_NOTCH_SIGNALING
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000100890.11chr1435122562:35122635:35122951:35124231-0.34656.1015e-033.1279e-05-0.4218imageNACIN1;ADAR;ALYREF;BUD13;CELF2;CNBP;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;FXR2;HNRNPA1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;LARP7;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI1;MSI2;NOP56;NOP58;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM47;SF3A3;SF3B4;SMNDC1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZNF184NAT_cells_CD4_memory_restingGSVA_HALLMARK_MTORC1_SIGNALING
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000089006.12chr2017968374:17968457:17968699:179689800.43208.6669e-047.5690e-070.4511imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NANK_cells_activatedGSVA_HALLMARK_MTORC1_SIGNALING
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000215193.8chr2218077922:18078047:18078295:180786060.34269.1046e-031.1143e-050.4258imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_ALLOGRAFT_REJECTION
chr9:92078561-92079375:-
TGCTEERIRENSG00000100890.11chr1435122562:35122635:35122951:35124231-0.34997.3185e-034.2856e-05-0.4217imageNELAVL1;MSI1NAT_cells_CD4_memory_restingGSVA_HALLMARK_MTORC1_SIGNALING
chr9:92078561-92079375:-
TGCTEERIRENSG00000073712.9chr1452881035:52881138:52881243:52881363-0.30761.0105e-026.3523e-05-0.4005imageNELAVL1;MSI1FERMT2NK_cells_activatedGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000066923.13chr7100211010:100211185:100211434:1002115390.36717.1577e-031.5809e-050.4114imageNACIN1;ADAR;CELF2;DGCR8;DKC1;EIF4A3;ELAVL1;EWSR1;FAM120A;FBL;FUS;HNRNPA1;HNRNPC;HNRNPL;HNRNPM;HNRNPU;IGF2BP1;IGF2BP2;KHSRP;LIN28B;LSM11;PRPF8;PTBP1;RBFOX2;RBM10;SF3A3;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;TAF15;TARBP2;TARDBP;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;YTHDC1NAT_cells_CD4_memory_restingGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000168002.7chr1162761636:62761904:62762541:627627420.33171.0076e-021.0806e-060.4738imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YWHAG;ZC3H7B;ZNF184POLR2GNeutrophilsGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr9:92078561-92079375:-
TGCTEERIRENSG00000123737.8chr4121813754:121814047:121816143:1218161940.38307.4082e-035.2337e-060.4207imageNELAVL1NAT_cells_CD4_memory_restingGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr9:92078561-92079375:-
TGCTEERESENSG00000198646.9chr2034736689:34736758:34740362:34743341:34746806:347469280.39043.0584e-033.0041e-050.4063imageNELAVL1;MSI1NCOA6Dendritic_cells_restingGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr9:92078561-92079375:-
TGCTEERIRENSG00000066923.13chr7100211010:100211185:100211437:1002115390.44846.1064e-041.0613e-060.4573imageNELAVL1NANK_cells_activatedGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr9:92078561-92079375:-
TGCTEERIRENSG00000066923.13chr7100211010:100211539:100211794:1002118760.45231.0641e-032.0625e-060.4349imageNELAVL1NAT_cells_CD4_memory_restingGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000186665.8chr1767991100:67993235:67993423:679935240.39091.8326e-031.1372e-050.4139imageNBUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DKC1;EIF4A3;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;FXR2;HNRNPA1;HNRNPC;HNRNPU;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28B;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PRPF8;PUM2;RANGAP1;RBM10;RBM47;SMNDC1;SND1;SRSF1;SRSF3;SRSF9;TAF15;TIA1;TIAL1;U2AF2;UPF1;ZC3H7B;ZNF184NANK_cells_activatedGSVA_HALLMARK_GLYCOLYSIS
chr9:92078561-92079375:-
TGCTEERMEXENSG00000189171.9chr1153626319:153626533:153626766:153627598:153628120:153628233:153631010:153631078-0.33443.0641e-039.9140e-05-0.4052imageNELAVL1S100A13T_cells_CD4_memory_activatedGSVA_HALLMARK_MTORC1_SIGNALING
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000116977.14chr1236540246:236543648:236544749:2365448150.39484.8887e-034.0688e-060.4164imageNADAR;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;KHSRP;LARP4B;LARP7;LIN28B;LSM11;MBNL2;METTL3;MOV10;MSI2;NONO;NOP56;NOP58;PCBP2;PRPF8;PTBP1;QKI;RBFOX2;RBM10;RBM22;RBM27;RBM47;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAGLGALS8B_cells_naiveGSVA_HALLMARK_COAGULATION
ENSG00000090054.12,SPTLC1
TGCTEAGA3ENSG00000060237.12chr12862234:862270:878211:878312:878214:878312-0.31391.1054e-022.3601e-05-0.4564imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM6;RC3H1;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184WNK1T_cells_regulatory_(Tregs)
chr9:92078561-92079375:-
TGCTEERIRENSG00000169738.3chr1782036632:82037013:82037449:820375410.47235.3733e-046.3151e-070.4521imageNELAVL1NAT_cells_CD4_memory_activatedGSVA_HALLMARK_MTORC1_SIGNALING
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000145029.7chr349422945:49424874:49424948:494250110.34488.5528e-031.0056e-050.4360imageNADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CPSF6;CSTF2T;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHSRP;LIN28;LIN28B;LSM11;MBNL2;METTL3;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM22;RBM27;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;ZNF184NAMonocytesGSVA_HALLMARK_DNA_REPAIR
ENSG00000090054.12,SPTLC1
TGCTEAGESENSG00000127586.12chr16794141:794201:795131:795356:795684:7957200.37363.9050e-039.4355e-060.4017imageNACIN1;AIFM1;ALYREF;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHSRP;LARP4B;LARP7;LIN28;LIN28B;LSM11;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YWHAG;ZNF184NANK_cells_activatedGSVA_HALLMARK_GLYCOLYSIS
ENSG00000090054.12,SPTLC1
TGCTEAGMEXENSG00000189171.9chr1153626319:153626533:153626766:153627598:153628120:153628233:153631010:153631078-0.33541.9663e-038.8423e-05-0.4013imageNACIN1;AUH;BCCIP;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHSRP;LARP7;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;TAF15;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;ZNF184S100A13T_cells_CD4_memory_activatedGSVA_HALLMARK_MTORC1_SIGNALING
chr9:92078561-92079375:-
TGCTEERIRENSG00000186665.8chr1767991100:67993235:67993423:679935240.35958.2559e-032.3356e-050.4057imageNELAVL1NANK_cells_activatedGSVA_HALLMARK_GLYCOLYSIS
chr9:92078561-92079375:-
TGCTEERESENSG00000127586.12chr16794141:794201:795131:795356:795684:7957200.37415.3765e-031.2095e-050.4022imageNELAVL1;MSI1NANK_cells_activatedGSVA_HALLMARK_GLYCOLYSIS
ENSG00000090054.12,SPTLC1
TGCTEAGESENSG00000060237.12chr12862234:862270:871264:871348:878211:8783120.39518.2070e-047.1747e-060.4605imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM6;RC3H1;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184WNK1B_cells_naiveGSVA_HALLMARK_GLYCOLYSIS
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000169738.3chr1782036632:82037013:82037449:820375410.43961.1309e-034.3524e-060.4152imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZNF184NAT_cells_CD4_memory_activatedGSVA_HALLMARK_MTORC1_SIGNALING
chr9:92078561-92079375:-
TGCTEERIRENSG00000143819.8chr1225841035:225842474:225844497:2258446230.43391.5823e-039.0741e-060.4074imageNELAVL1;MSI1NAT_cells_CD4_memory_restingGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000123737.8chr4121813754:121814047:121816143:1218161940.37666.7370e-039.8065e-060.4043imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;KHSRP;LIN28;LIN28A;LIN28B;LSM11;MOV10;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM6;SF3A3;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YWHAG;ZC3H7B;ZNF184NAT_cells_CD4_memory_restingGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000119650.8chr1475985752:75985840:75986125:759862820.39496.2742e-044.0356e-060.4643imageNACIN1;ADAR;AIFM1;AUH;CELF2;CNBP;CSTF2T;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;FAM120A;FBL;FTO;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;LARP4B;LIN28;LIN28A;LIN28B;MBNL2;METTL3;MOV10;MSI1;MSI2;NOP56;NOP58;PRPF8;PTBP1;QKI;RBFOX2;RBM10;SLBP;SMNDC1;SRSF1;SRSF10;SRSF3;SRSF7;TAF15;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;YTHDC1;YTHDF1NAT_cells_CD4_naiveGSVA_HALLMARK_GLYCOLYSIS
chr9:92078561-92079375:-
TGCTEERIRENSG00000117122.9chr116976707:16976923:16978236:169782760.30811.5143e-021.4693e-040.4026imageNNNANK_cells_activatedGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr9:92078561-92079375:-
TGCTEERIRENSG00000118046.10chr191222950:1223172:1223637:12266630.32681.1744e-027.4368e-050.4209imageNELAVL1;MSI1NAB_cells_naiveGSVA_HALLMARK_MITOTIC_SPINDLE
chr9:92078561-92079375:-
TGCTEERIRENSG00000089006.12chr2017968374:17968457:17968699:179689800.42521.8065e-037.9021e-070.4562imageNELAVL1;MSI1NANK_cells_activatedGSVA_HALLMARK_MTORC1_SIGNALING
chr9:92078561-92079375:-
TGCTEERIRENSG00000188368.5chr1942308773:42310185:42310270:423102880.35155.0104e-034.6124e-050.4114imageNELAVL1NANK_cells_activatedGSVA_HALLMARK_MTORC1_SIGNALING
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000073712.9chr1452881035:52881138:52881243:52881363-0.29771.1293e-024.5791e-05-0.4015imageNACIN1;ADAR;AUH;BCCIP;BUD13;CELF2;CNBP;CSTF2T;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;LARP4B;LARP7;LIN28;LIN28A;LIN28B;MBNL2;METTL3;MOV10;MSI1;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM47;RC3H1;SF3A3;SF3B4;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;YTHDC1;YTHDF1;ZNF184FERMT2NK_cells_activatedGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000143819.8chr1225841035:225842474:225844497:2258446230.43818.3494e-048.3877e-060.4038imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP1;IGF2BP2;IGF2BP3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;MOV10;MSI1;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;YTHDC1;YTHDF1;ZC3H7B;ZNF184NAT_cells_CD4_memory_restingGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000140416.15chr1563062575:63064190:63065895:630660930.33523.4349e-036.2121e-050.4009imageNACIN1;ADAR;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM6;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184TPM1B_cells_naiveGSVA_HALLMARK_GLYCOLYSIS
chr9:92078561-92079375:-
TGCTEERIRENSG00000215193.8chr2218077922:18078047:18078295:180786060.33431.5514e-022.2264e-050.4183imageNELAVL1NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_ALLOGRAFT_REJECTION
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000118046.10chr191222950:1223172:1223637:12266630.33197.4299e-034.5174e-050.4250imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RC3H1;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YWHAG;ZNF184NAB_cells_naiveGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000066923.13chr7100211010:100211539:100211794:1002118760.46553.6472e-041.1031e-060.4397imageNACIN1;ADAR;CELF2;DGCR8;DKC1;EIF4A3;ELAVL1;EWSR1;FAM120A;FBL;FUS;HNRNPA1;HNRNPC;HNRNPL;HNRNPM;HNRNPU;IGF2BP1;IGF2BP2;KHSRP;LIN28B;LSM11;PRPF8;PTBP1;RBFOX2;RBM10;SF3A3;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;TAF15;TARBP2;TARDBP;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;YTHDC1NAT_cells_CD4_memory_restingGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr9:92078561-92079375:-
TGCTEERMEXENSG00000101126.11chr2050903888:50904001:50918660:50918781:50928650:50928742:50930825:509312130.23584.8354e-021.3047e-040.4032imageNELAVL1;MSI1ADNPB_cells_memoryGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr9:92078561-92079375:-
TGCTEERA3ENSG00000239382.6chr1936011403:36011464:36010543:36011077:36010543:36011045-0.43891.4350e-034.2627e-06-0.4208imageNELAVL1NAMacrophages_M2GSVA_HALLMARK_GLYCOLYSIS
ENSG00000090054.12,SPTLC1
TGCTEAGESENSG00000012822.11chr1253711789:53712121:53712774:53712846:53713099:537132030.33201.7826e-021.7140e-050.4009imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL3;MOV10;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM27;RBM47;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;ZNF184NANK_cells_activatedGSVA_HALLMARK_GLYCOLYSIS
chr9:92078561-92079375:-
TGCTEERA3ENSG00000125676.15chrX123610917:123610957:123600568:123601338:123600568:123603748-0.42762.5708e-037.6092e-06-0.4106imageNELAVL1;MSI1NAT_cells_CD4_memory_restingGSVA_HALLMARK_UV_RESPONSE_DN
chr9:92078561-92079375:-
TGCTEERIRENSG00000066923.13chr7100211010:100211185:100211434:1002115390.36311.0798e-022.1672e-050.4090imageNELAVL1NAT_cells_CD4_memory_restingGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
ENSG00000090054.12,SPTLC1
TGCTEAGESENSG00000071054.11chr2101856119:101856138:101858995:101859082:101859642:101859864-0.26894.5104e-023.4855e-05-0.4014imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM6;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YWHAG;ZC3H7B;ZNF184MAP4K4Macrophages_M2GSVA_HALLMARK_ESTROGEN_RESPONSE_EARLY
ENSG00000090054.12,SPTLC1
TGCTEAGA3ENSG00000239382.6chr1936011403:36011464:36010543:36011077:36010543:36011045-0.44885.9251e-042.0844e-06-0.4276imageNACIN1;ADAR;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;EIF4A3;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDF1;YWHAG;ZNF184NAMacrophages_M2GSVA_HALLMARK_GLYCOLYSIS
chr9:92078561-92079375:-
TGCTEERA3ENSG00000124541.6chr643026072:43026141:43027192:43027252:43027129:43027252-0.32531.0862e-023.2712e-05-0.4065imageNELAVL1;MSI1NAT_cells_CD8GSVA_HALLMARK_P53_PATHWAY
chr9:92078561-92079375:-
TGCTEERMEXENSG00000101126.11chr2050903888:50904001:50918660:50918781:50928650:50928852:50930825:509312130.24024.1794e-021.0757e-040.4077imageNELAVL1;MSI1ADNPB_cells_memoryGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000066923.13chr7100211010:100211185:100211437:1002115390.45132.9833e-046.1038e-070.4603imageNACIN1;ADAR;CELF2;DGCR8;DKC1;EIF4A3;ELAVL1;EWSR1;FAM120A;FBL;FUS;HNRNPA1;HNRNPC;HNRNPL;HNRNPM;HNRNPU;IGF2BP1;IGF2BP2;KHSRP;LIN28B;LSM11;PRPF8;PTBP1;RBFOX2;RBM10;SF3A3;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;TAF15;TARBP2;TARDBP;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;YTHDC1NANK_cells_activatedGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr9:92078561-92079375:-
TGCTEERIRENSG00000145029.7chr349422945:49424874:49424948:494250110.32462.1017e-023.7597e-050.4158imageNELAVL1NAMonocytesGSVA_HALLMARK_DNA_REPAIR
chr9:92078561-92079375:-
TGCTEERIRENSG00000119650.8chr1475985752:75985840:75986125:759862820.37762.1420e-031.0444e-050.4508imageNELAVL1;MSI1NAT_cells_CD4_naiveGSVA_HALLMARK_GLYCOLYSIS
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000188368.5chr1942308773:42310185:42310270:423102880.35163.5200e-034.9561e-050.4038imageNADAR;EIF4A3;ELAVL1;FBL;FMR1;FUS;HNRNPA1;HNRNPC;HNRNPM;IGF2BP1;IGF2BP2;IGF2BP3;NOP58;PCBP2;PTBP1;RBM10;SRSF1;SRSF10;SRSF3;U2AF2;UPF1;YTHDF1NANK_cells_activatedGSVA_HALLMARK_MTORC1_SIGNALING
chr9:92078561-92079375:-
TGCTEERESENSG00000060237.12chr12862234:862270:871264:871348:878211:8783120.38941.6771e-031.0939e-050.4596imageNELAVL1;MSI1WNK1B_cells_naiveGSVA_HALLMARK_GLYCOLYSIS
chr9:92078561-92079375:-
TGCTEERA3ENSG00000060237.12chr12862234:862270:878211:878312:878214:878312-0.30611.8407e-026.2031e-05-0.4428imageNELAVL1;MSI1WNK1T_cells_regulatory_(Tregs)
chr9:92078561-92079375:-
TGCTEERIRENSG00000168002.7chr1162761636:62761904:62762541:627627420.31162.4504e-024.0706e-060.4550imageNELAVL1POLR2GNeutrophilsGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr9:92078561-92079375:-
TGCTEERIRENSG00000116977.14chr1236540246:236543648:236544749:2365448150.38957.9195e-032.9968e-060.4268imageNELAVL1LGALS8B_cells_naiveGSVA_HALLMARK_COAGULATION
ENSG00000090054.12,SPTLC1
TGCTEAGIRENSG00000117122.9chr116976707:16976923:16978236:169782760.32775.5772e-034.5244e-050.4250imageNCSTF2T;DGCR8;DKC1;FBL;FMR1;FUS;HNRNPA2B1;HNRNPK;LIN28;NOP56;PRPF8;PTBP1;RANGAP1;RBFOX2;SRSF1;TAF15;TARDBP;U2AF2;ZNF184NANK_cells_activatedGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr9:92078561-92079375:-
TGCTEERIRENSG00000140416.15chr1563062575:63064190:63065895:630660930.35282.3810e-031.7403e-050.4316imageNELAVL1;MSI1TPM1B_cells_naiveGSVA_HALLMARK_GLYCOLYSIS