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3. Enriched editing regions and immune related genes for MED13


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark gene sets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr17:61998582-62001083:-ESCAEERENSG00000065833,ME10.30881.2363e-021.0781e-090.4678imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr17:61998582-62001083:-ESCAEERENSG00000111907,TPD52L10.30591.4345e-024.8877e-090.4510imageNNTPD52L1T_cells_CD4_memory_restingGSVA_HALLMARK_KRAS_SIGNALING_DN
chr17:61998582-62001083:-ESCAEERENSG00000146373,RNF2170.28462.4100e-029.2976e-080.4154imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_PANCREAS_BETA_CELLS
chr17:61998582-62001083:-ESCAEERENSG00000200651,Y_RNA-0.47734.9233e-061.1765e-07-0.4124imageNNNAB_cells_naiveGSVA_HALLMARK_SPERMATOGENESIS
chr17:61998582-62001083:-ESCAEERENSG00000200953,Y_RNA-0.45741.5439e-059.6056e-09-0.4432imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_GLYCOLYSIS
chr17:61998582-62001083:-ESCAEERENSG00000250461,RP11-631M6.2-0.46361.1746e-054.7795e-08-0.4238imageNNNAT_cells_CD4_memory_restingGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING
chr17:61998582-62001083:-ESCAEERENSG00000257246,RP11-416A17.6-0.45422.2835e-053.5999e-08-0.4274imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_P53_PATHWAY
chr17:61998582-62001083:-ESCAEERENSG00000259556,RP11-56B16.2-0.49481.4439e-067.5314e-09-0.4461imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_MTORC1_SIGNALING
chr17:61998582-62001083:-ESCAEERENSG00000269688,AC008982.2-0.46241.5097e-059.6340e-09-0.4432imageNNNAB_cells_naiveGSVA_HALLMARK_GLYCOLYSIS
chr17:61998582-62001083:-ESCAEERENSG00000276850,CH17-360D5.20.25794.9963e-021.8010e-080.4358imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_MTORC1_SIGNALING
chr17:61998582-62001083:-ESCAEERENSG00000279078,SND1-IT1-0.46811.6467e-052.3770e-08-0.4324imageNNNAB_cells_naiveGSVA_HALLMARK_ESTROGEN_RESPONSE_LATE
ENSG00000108510.8,MED13ESCAEAGENSG00000186615,KTN1-AS10.37581.3342e-033.3280e-080.4258imageNADAR;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FUS;GTF2F1;HNRNPA1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;KHSRP;LARP7;LIN28;LIN28B;MOV10;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RBFOX2;RBM10;RBM47;RBM5;SAFB2;SLTM;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TROVE2;U2AF1;U2AF2;UPF1;YTHDC1;ZC3H7BNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_BILE_ACID_METABOLISM
ENSG00000108510.8,MED13ESCAEAGENSG00000200651,Y_RNA-0.49091.9624e-061.6979e-08-0.4339imageNNNAB_cells_naiveGSVA_HALLMARK_SPERMATOGENESIS
ENSG00000108510.8,MED13ESCAEAGENSG00000200953,Y_RNA-0.44044.3914e-056.7519e-09-0.4447imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_GLYCOLYSIS
ENSG00000108510.8,MED13ESCAEAGENSG00000225195,RP11-338E21.2-0.47684.5242e-061.5520e-08-0.4350imageNADAR;CNBP;DHX9;EIF4A3;ELAVL1;FBL;HNRNPA1;HNRNPC;HNRNPU;IGF2BP2;KHDRBS1;KHSRP;NOP56;PTBP1;SAFB2;TAF15;TARBP2;TARDBP;U2AF2NADendritic_cells_restingGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING
ENSG00000108510.8,MED13ESCAEAGENSG00000257246,RP11-416A17.6-0.40124.3200e-041.8286e-07-0.4042imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_P53_PATHWAY
ENSG00000108510.8,MED13ESCAEAGENSG00000259556,RP11-56B16.2-0.48472.6438e-061.5864e-09-0.4609imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_MTORC1_SIGNALING
ENSG00000108510.8,MED13ESCAEAGENSG00000269688,AC008982.2-0.44165.3482e-053.2941e-08-0.4259imageNBCCIP;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DGCR8;DHX9;DICER1;ELAVL1;FAM120A;FBL;FMR1;FTO;FXR1;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPM;HNRNPU;IGF2BP2;ILF3;KHDRBS1;KHSRP;LIN28;NONO;NOP56;NOP58;NUMA1;PRPF8;PTBP1;RBFOX2;RBM10;RNF219;SLTM;SND1;SRSF1;SRSF10;TAF15;TARBP2;TIA1;TIAL1;U2AF1;U2AF2;UPF1;VIM;ZNF184NAB_cells_naiveGSVA_HALLMARK_GLYCOLYSIS