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3. Enriched editing regions and immune related genes for HAVCR2


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark gene sets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr5:157133784-157134472:-THYMEERENSG00000074590,NUAK10.24474.2017e-021.8637e-060.4312imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_ANGIOGENESIS
chr5:157133784-157134472:-THYMEERENSG00000099284,H2AFY20.33474.2075e-035.2749e-060.4136imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_ANGIOGENESIS
chr5:157133784-157134472:-THYMEERENSG00000114631,PODXL20.28111.9955e-023.1685e-070.4590imageNNPODXL2Macrophages_M1GSVA_HALLMARK_CHOLESTEROL_HOMEOSTASIS
chr5:157133784-157134472:-THYMEERENSG00000118515,SGK10.26523.3001e-025.1077e-090.5156imageNNSGK1T_cells_CD4_memory_activatedGSVA_HALLMARK_HYPOXIA
chr5:157133784-157134472:-THYMEERENSG00000128283,CDC42EP10.26303.5803e-026.6703e-070.4476imageNNNAT_cells_CD4_memory_activatedGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASIS
chr5:157133784-157134472:-THYMEERENSG00000135094,SDS0.29011.7847e-023.3211e-060.4216imageNNNAT_cells_CD4_memory_activatedGSVA_HALLMARK_APOPTOSIS
chr5:157133784-157134472:-THYMEERENSG00000136999,NOV0.26353.3238e-021.1178e-070.4743imageNNNADendritic_cells_activatedGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKB
chr5:157133784-157134472:-THYMEERENSG00000148120,C9orf30.27472.6195e-029.5191e-060.4032imageNNNADendritic_cells_activatedGSVA_HALLMARK_ANGIOGENESIS
chr5:157133784-157134472:-THYMEERENSG00000159182,PRAC10.14871.8026e-022.3049e-060.4277imageNNNANeutrophilsGSVA_HALLMARK_ESTROGEN_RESPONSE_LATE
chr5:157133784-157134472:-THYMEERENSG00000166387,PPFIBP20.26342.5961e-023.2108e-070.4588imageNNNAMacrophages_M1GSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKB
chr5:157133784-157134472:-THYMEERENSG00000169313,P2RY120.26042.5945e-021.3591e-060.4363imageNNP2RY12NK_cells_activatedGSVA_HALLMARK_SPERMATOGENESIS
chr5:157133784-157134472:-THYMEERENSG00000171729,TMEM510.26832.0656e-028.6187e-060.4050imageNNNAMacrophages_M1GSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKB
chr5:157133784-157134472:-THYMEERENSG00000196793,ZNF2390.29441.5291e-025.8989e-060.4117imageNNNADendritic_cells_activatedGSVA_HALLMARK_ESTROGEN_RESPONSE_EARLY
chr5:157133784-157134472:-THYMEERENSG00000264148,RP11-848P1.70.30948.5521e-035.2163e-070.4514imageNNNAMacrophages_M1GSVA_HALLMARK_G2M_CHECKPOINT
ENSG00000135077.7,HAVCR2THYMEAGENSG00000099284,H2AFY20.36891.2989e-031.7718e-060.4303imageNADAR;BCCIP;CNBP;CSTF2T;DDX54;DGCR8;DICER1;DKC1;ELAVL1;FAM120A;FBL;FMR1;FUS;GTF2F1;HNRNPA1;HNRNPL;HNRNPM;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHDRBS2;LARP4B;LIN28;LIN28B;MOV10;NOP56;NOP58;PCBP2;PRPF8;RANGAP1;RBFOX2;RBM10;SND1;SRSF1;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TRA2A;U2AF2;UPF1NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_ANGIOGENESIS
ENSG00000135077.7,HAVCR2THYMEAGENSG00000104312,RIPK20.27832.2172e-021.8823e-080.4968imageNACIN1;ADAR;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DKC1;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS2;KHSRP;LIN28;LIN28B;MOV10;MSI2;NOP56;NOP58;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM47;RNF219;SAFB2;SLTM;SND1;SRSF1;SRSF10;SRSF7;SRSF9;TAF15;TARDBP;TRA2A;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;ZNF184RIPK2Macrophages_M1GSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKB
ENSG00000135077.7,HAVCR2THYMEAGENSG00000107372,ZFAND50.28581.9386e-025.8020e-060.4103imageNACIN1;ADAR;ALYREF;BCCIP;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28B;LSM11;MBNL2;MOV10;MSI2;NOP56;NOP58;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM47;RNF219;SAFB2;SLTM;SND1;SRSF1;SRSF10;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TRA2A;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;ZC3H7B;ZNF184ZFAND5Macrophages_M1GSVA_HALLMARK_HYPOXIA
ENSG00000135077.7,HAVCR2THYMEAGENSG00000114631,PODXL20.27982.1801e-024.5104e-070.4518imageNACIN1;ADAR;BCCIP;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPL;HNRNPM;IGF2BP1;IGF2BP2;IGF2BP3;LARP4B;LIN28;LIN28B;LSM11;MBNL2;MOV10;MSI2;NOP56;NOP58;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;SLTM;SND1;SRSF1;SRSF10;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1PODXL2Macrophages_M1GSVA_HALLMARK_CHOLESTEROL_HOMEOSTASIS
ENSG00000135077.7,HAVCR2THYMEAGENSG00000118515,SGK10.29961.4169e-025.8402e-090.5119imageNACIN1;ADAR;ALYREF;BCCIP;BUD13;CPSF6;CSTF2T;DDX54;DGCR8;DKC1;EIF4A3;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHDRBS2;KHSRP;LIN28;LIN28B;LSM11;MBNL2;MOV10;NOP56;NOP58;PCBP2;PRPF8;PTBP1;RBFOX2;RBM10;RBM47;SAFB2;SLTM;SND1;SRSF1;SRSF10;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1SGK1T_cells_CD4_memory_activatedGSVA_HALLMARK_HYPOXIA
ENSG00000135077.7,HAVCR2THYMEAGENSG00000128283,CDC42EP10.25214.8747e-029.1217e-070.4409imageNADAR;BCCIP;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LARP4B;LIN28;LIN28B;LSM11;MBNL2;MOV10;MSI2;NOP56;NOP58;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RNF219;SAFB2;SLTM;SND1;SRSF1;SRSF10;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TRA2A;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;ZNF184NAT_cells_CD4_memory_activatedGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASIS
ENSG00000135077.7,HAVCR2THYMEAGENSG00000136999,NOV0.26583.3170e-021.6438e-070.4668imageNDKC1;EIF4A3;ELAVL1;FBL;FUS;IGF2BP2;IGF2BP3;KHDRBS2;MBNL2;MOV10;PTBP1;RBM47;SRSF1;SRSF10;TIA1;TIAL1;U2AF2;UPF1;YTHDF1NADendritic_cells_activatedGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKB
ENSG00000135077.7,HAVCR2THYMEAGENSG00000148120,C9orf30.31558.9694e-035.3827e-060.4116imageNACIN1;ADAR;ALYREF;BCCIP;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPL;HNRNPM;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHDRBS2;KHSRP;LIN28;LIN28B;LSM11;MBNL2;MOV10;NOP56;NOP58;PCBP2;PRPF8;PTBP1;RBFOX2;RBM10;RBM47;SLTM;SND1;SRSF1;SRSF10;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;ZC3H7B;ZNF184NADendritic_cells_activatedGSVA_HALLMARK_ANGIOGENESIS
ENSG00000135077.7,HAVCR2THYMEAGENSG00000159182,PRAC10.14981.7882e-023.3149e-060.4199imageNDDX54NANeutrophilsGSVA_HALLMARK_ESTROGEN_RESPONSE_LATE
ENSG00000135077.7,HAVCR2THYMEAGENSG00000166387,PPFIBP20.24624.2390e-026.2358e-070.4468imageNACIN1;ADAR;BCCIP;BUD13;CNBP;CSTF2T;DDX3X;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;GTF2F1;HNRNPA1;HNRNPC;HNRNPL;HNRNPM;HNRNPU;IGF2BP1;IGF2BP2;IGF2BP3;LIN28B;MBNL2;MSI2;NOP56;NOP58;PCBP2;PRPF8;PTBP1;RBFOX2;SAFB2;SLTM;SND1;SRSF1;SRSF10;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TRA2A;U2AF1;U2AF2;UPF1;XRN2;YTHDF1;ZNF184NAMacrophages_M1GSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKB
ENSG00000135077.7,HAVCR2THYMEAGENSG00000169313,P2RY120.28391.4102e-021.7565e-060.4304imageNADAR;DKC1;EIF4A3;ELAVL1;FBL;FUS;HNRNPL;NOP58;TAF15;UPF1P2RY12NK_cells_activatedGSVA_HALLMARK_SPERMATOGENESIS
ENSG00000135077.7,HAVCR2THYMEAGENSG00000196793,ZNF2390.33524.6933e-032.5479e-060.4243imageNADAR;CNBP;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DKC1;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FUS;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPL;HNRNPM;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHSRP;LARP4B;LIN28B;LSM11;MOV10;NOP56;NOP58;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;SAFB2;SLTM;SRSF1;SRSF10;TAF15;TARDBP;TIAL1;U2AF2;UPF1;XRN2;YTHDF1;ZC3H7B;ZFP36;ZNF184NADendritic_cells_activatedGSVA_HALLMARK_ESTROGEN_RESPONSE_EARLY
ENSG00000135077.7,HAVCR2THYMEAGENSG00000255769,GOLGA2P100.28851.9397e-028.3729e-070.4423imageNNNAEosinophilsGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKB
ENSG00000135077.7,HAVCR2THYMEAGENSG00000264148,RP11-848P1.70.27692.2590e-024.3462e-060.4153imageNNNAMacrophages_M1GSVA_HALLMARK_G2M_CHECKPOINT