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3. Enriched editing regions and immune related genes for HMGB1


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark gene sets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000189403.13,HMGB1KIRCEAGENSG00000154655,L3MBTL40.19211.3963e-022.1441e-130.4051imageNACIN1;ADAR;AIFM1;BCCIP;BUD13;CELF2;CNBP;CSTF2T;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHDRBS2;KHDRBS3;LARP7;LIN28;LIN28A;LIN28B;MBNL2;MOV10;MSI1;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM47;SF3A3;SF3B4;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TROVE2;U2AF2;UPF1;YTHDC1NAT_cells_CD4_memory_restingGSVA_HALLMARK_COAGULATION
ENSG00000189403.13,HMGB1KIRCEAGENSG00000276182,RP11-872J21.50.19381.2026e-023.5741e-160.4454imageNADAR;CPSF6;CSTF2T;EIF4A3;ELAVL1;ELAVL3;FBL;FMR1;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHDRBS2;KHDRBS3;MOV10;NOP58;PRPF8;RBFOX2;RBM10;RBM47;SAFB2;SMNDC1;SRSF1;SRSF10;TARDBP;TROVE2;U2AF2;UPF1NAT_cells_CD4_memory_restingGSVA_HALLMARK_P53_PATHWAY