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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: ZNF518A (ImmuneEditome ID:9849)

1. Gene summary of enriched editing regions for ZNF518A

check button Gene summary
Gene informationGene symbol

ZNF518A

Gene ID

9849

GeneSynonymsZNF518
GeneCytomap

10q24.1

GeneTypeprotein-coding
GeneDescriptionzinc finger protein 518A|zinc finger protein 518
GeneModificationdate20230517
UniprotIDQ6AHZ1
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr10:96144041-96144270:+ENST00000488700.4ENSG00000177853.13ZNF518AncRNA_intronicAluJbchr10:96144041-96144270:+.alignment
chr10:96144041-96144270:+ENST00000539666.4ENSG00000177853.13ZNF518AncRNA_intronicAluJbchr10:96144041-96144270:+.alignment
chr10:96144041-96144270:+ENST00000563195.1ENSG00000177853.13ZNF518AncRNA_intronicAluJbchr10:96144041-96144270:+.alignment
chr10:96150051-96150236:+ENST00000488700.4ENSG00000177853.13ZNF518AncRNA_intronicAluYchr10:96150051-96150236:+.alignment
chr10:96150051-96150236:+ENST00000539666.4ENSG00000177853.13ZNF518AncRNA_intronicAluYchr10:96150051-96150236:+.alignment
chr10:96150051-96150236:+ENST00000563195.1ENSG00000177853.13ZNF518AncRNA_intronicAluYchr10:96150051-96150236:+.alignment
chr10:96165138-96165379:+ENST00000442635.2ENSG00000177853.13ZNF518AncRNA_intronicAluSx1chr10:96165138-96165379:+.alignment
chr10:96165138-96165379:+ENST00000563195.1ENSG00000177853.13ZNF518AncRNA_intronicAluSx1chr10:96165138-96165379:+.alignment
chr10:96166465-96167619:+ENST00000442635.2ENSG00000177853.13ZNF518AncRNA_intronicAluSz,L1M4b,AluYchr10:96166465-96167619:+.alignment
chr10:96166465-96167619:+ENST00000563195.1ENSG00000177853.13ZNF518AncRNA_intronicAluSz,L1M4b,AluYchr10:96166465-96167619:+.alignment


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2. Tumor-specific enriched editing regions for ZNF518A


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
ENSG00000177853.13,ZNF518ASTADEAG2.2763e-03image


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
chr10:96166465-96167619:+BLCAPathEER6.5988e-032.7505e-030.2549image
ENSG00000177853.13,ZNF518ABLCAPathEAG2.6130e-021.6176e-020.2008image
ENSG00000177853.13,ZNF518AKIRCPathEAG1.2950e-021.0766e-030.2120image
chr10:96166465-96167619:+KIRCPathEER1.0761e-021.0113e-030.2154image
chr10:96166465-96167619:+OVCliEER6.4305e-034.6396e-030.1956image


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
chr10:96166465-96167619:+SARCEER3.9353e-044.9555e-023.0810e+01image
ENSG00000177853.13,ZNF518ASARCEAG3.9353e-044.9555e-023.0810e+01image

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3. Enriched editing regions and immune related genes for ZNF518A


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark

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4. Enriched editing regions and immune related splicing for ZNF518A


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000177853.13,ZNF518A
STADEAGIRENSG00000204138.8chr128490950:28491012:28491649:28491787-0.40902.7393e-094.6505e-13-0.4029imageNADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NANK_cells_restingGSVA_HALLMARK_HEME_METABOLISM
ENSG00000177853.13,ZNF518A
STADEAGIRENSG00000119431.5chr9113375452:113375567:113376728:113376925-0.39976.2247e-097.2093e-13-0.4005imageNAUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FKBP4;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;LIN28;LSM11;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM27;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TRA2A;U2AF1;U2AF2;XRN2;YTHDC1;YTHDF1;ZNF184NAMacrophages_M2GSVA_HALLMARK_HYPOXIA
ENSG00000177853.13,ZNF518A
STADEAGIRENSG00000168137.11chr39464409:9464672:9470458:9470929-0.39947.6120e-093.8275e-13-0.4055imageNADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAMacrophages_M2GSVA_HALLMARK_HYPOXIA

More results



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5. Enriched editing regions and immune infiltration for ZNF518A


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chr10:96166465-96167619:+BLCAEERB_cells_memory1.4281e-03-0.2699image
ENSG00000177853.13,ZNF518ABLCAEAGB_cells_memory1.2262e-03-0.2677image
chr10:96166465-96167619:+CHOLEERNK_cells_activated3.0808e-020.4162image
ENSG00000177853.13,ZNF518ACHOLEAGNK_cells_activated3.2886e-020.4117image
chr10:96166465-96167619:+COADEERDendritic_cells_activated2.0354e-020.1952image
ENSG00000177853.13,ZNF518ACOADEAGDendritic_cells_activated1.4777e-030.2532image
chr10:96166465-96167619:+ESCAEERMacrophages_M29.7629e-040.3143image
chr10:96166465-96167619:+KIRPEERMacrophages_M19.6018e-030.2505image
ENSG00000177853.13,ZNF518AKIRPEAGMacrophages_M13.9600e-020.1956image
chr10:96166465-96167619:+LAMLEERT_cells_CD81.2164e-030.4405image
ENSG00000177853.13,ZNF518ALAMLEAGT_cells_CD82.3491e-020.2231image
chr10:96166465-96167619:+LUADEERMacrophages_M14.7788e-020.1572image
chr10:96166465-96167619:+PAADEERT_cells_CD4_naive4.9620e-020.2175image
ENSG00000177853.13,ZNF518APAADEAGT_cells_CD4_naive4.7070e-020.2186image
chr10:96165138-96165379:+PRADEERMacrophages_M14.8245e-020.3143image
chr10:96166465-96167619:+READEERNeutrophils4.0730e-020.2905image
ENSG00000177853.13,ZNF518AREADEAGT_cells_CD4_memory_activated4.9983e-020.2787image
chr10:96166465-96167619:+SARCEERT_cells_CD82.5574e-030.4941image
ENSG00000177853.13,ZNF518ASARCEAGT_cells_CD83.3516e-030.4759image
chr10:96166465-96167619:+SKCMEERPlasma_cells1.5882e-03-0.3394image
ENSG00000177853.13,ZNF518ASKCMEAGPlasma_cells1.7078e-03-0.3372image
chr10:96150051-96150236:+STADEERNK_cells_resting5.2897e-030.5404image
chr10:96166465-96167619:+STADEERT_cells_CD81.0806e-020.1594image
ENSG00000177853.13,ZNF518ASTADEAGT_cells_CD4_memory_activated9.9316e-040.1898image
chr10:96166465-96167619:+TGCTEERT_cells_regulatory_(Tregs)1.4459e-020.3373image
ENSG00000177853.13,ZNF518ATGCTEAGT_cells_regulatory_(Tregs)1.2997e-020.3423image
chr10:96166465-96167619:+THCAEERB_cells_naive5.3766e-030.2084image
ENSG00000177853.13,ZNF518ATHCAEAGDendritic_cells_resting1.2792e-020.1822image
chr10:96166465-96167619:+THYMEERT_cells_CD4_memory_resting9.6006e-030.3526image
ENSG00000177853.13,ZNF518ATHYMEAGT_cells_regulatory_(Tregs)8.8304e-03-0.3563image
chr10:96166465-96167619:+UCECEERNK_cells_resting2.2975e-020.2641image
ENSG00000177853.13,ZNF518AUCECEAGEosinophils2.5620e-02-0.2527image


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6. Enriched editing regions and immune gene sets for ZNF518A


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
chr10:96166465-96167619:+BLCAGSVA_HALLMARK_GLYCOLYSISEER8.5371e-050.3293image
ENSG00000177853.13,ZNF518ABLCAGSVA_HALLMARK_GLYCOLYSISEAG8.8956e-050.3218image
chr10:96165138-96165379:+BLCAGSVA_HALLMARK_PROTEIN_SECRETIONEER2.5773e-020.4066image
ENSG00000177853.13,ZNF518ABRCAGSVA_HALLMARK_BILE_ACID_METABOLISMEAG3.5595e-030.1178image
chr10:96166465-96167619:+BRCAGSVA_HALLMARK_XENOBIOTIC_METABOLISMEER1.7301e-030.1297image
ENSG00000177853.13,ZNF518ACESCGSVA_HALLMARK_INFLAMMATORY_RESPONSEEAG3.3058e-030.3618image
chr10:96166465-96167619:+CESCGSVA_HALLMARK_INFLAMMATORY_RESPONSEEER1.3170e-030.3930image
chr10:96166465-96167619:+CHOLGSVA_HALLMARK_MYC_TARGETS_V1EER3.3574e-020.4102image
ENSG00000177853.13,ZNF518ACHOLGSVA_HALLMARK_MYC_TARGETS_V1EAG3.4195e-020.4089image
chr10:96166465-96167619:+ESCAGSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITIONEER7.6222e-030.2566image
ENSG00000177853.13,ZNF518AESCAGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG2.6667e-020.1929image
ENSG00000177853.13,ZNF518AKICHGSVA_HALLMARK_UV_RESPONSE_UPEAG2.9863e-03-0.6153image
chr10:96166465-96167619:+KICHGSVA_HALLMARK_UV_RESPONSE_UPEER3.6894e-03-0.6179image
ENSG00000177853.13,ZNF518AKIRCGSVA_HALLMARK_MYC_TARGETS_V2EAG2.2876e-030.2366image
chr10:96166465-96167619:+KIRCGSVA_HALLMARK_MYC_TARGETS_V2EER4.4460e-030.2245image
chr10:96166465-96167619:+KIRPGSVA_HALLMARK_PANCREAS_BETA_CELLSEER2.6450e-020.2156image
ENSG00000177853.13,ZNF518AKIRPGSVA_HALLMARK_DNA_REPAIREAG3.2850e-02-0.2027image
ENSG00000177853.13,ZNF518ALAMLGSVA_HALLMARK_BILE_ACID_METABOLISMEAG3.7576e-030.2831image
ENSG00000177853.13,ZNF518ALGGGSVA_HALLMARK_MYOGENESISEAG5.5345e-030.1713image
chr10:96166465-96167619:+LGGGSVA_HALLMARK_MYOGENESISEER1.2202e-030.2007image
chr10:96166465-96167619:+LIHCGSVA_HALLMARK_ALLOGRAFT_REJECTIONEER3.1300e-02-0.2380image
ENSG00000177853.13,ZNF518ALIHCGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG3.8836e-02-0.2286image
ENSG00000177853.13,ZNF518ALUADGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG9.5447e-030.2000image
chr10:96166465-96167619:+LUADGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER2.6744e-020.1757image
chr10:96166465-96167619:+LUSCGSVA_HALLMARK_NOTCH_SIGNALINGEER5.8283e-030.2917image
ENSG00000177853.13,ZNF518ALUSCGSVA_HALLMARK_NOTCH_SIGNALINGEAG1.7479e-020.2514image
chr10:96166465-96167619:+OVGSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITIONEER4.7187e-030.2230image
ENSG00000177853.13,ZNF518AOVGSVA_HALLMARK_APICAL_JUNCTIONEAG1.9111e-030.2292image
ENSG00000177853.13,ZNF518APCPGGSVA_HALLMARK_MYC_TARGETS_V1EAG4.8046e-03-0.3782image
chr10:96166465-96167619:+PCPGGSVA_HALLMARK_MYC_TARGETS_V1EER4.4896e-03-0.3809image
ENSG00000177853.13,ZNF518ASARCGSVA_HALLMARK_APICAL_SURFACEEAG1.1412e-020.4170image
chr10:96166465-96167619:+SARCGSVA_HALLMARK_APICAL_SURFACEEER1.4573e-020.4095image
chr10:96166465-96167619:+SKCMGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEER1.5905e-030.3393image
ENSG00000177853.13,ZNF518ASKCMGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEAG1.7583e-030.3364image
chr10:96150051-96150236:+STADGSVA_HALLMARK_DNA_REPAIREER1.7019e-020.4727image
ENSG00000177853.13,ZNF518ASTADGSVA_HALLMARK_IL2_STAT5_SIGNALINGEAG5.3861e-100.3496image
chr10:96166465-96167619:+STADGSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITIONEER1.0611e-030.2039image
ENSG00000177853.13,ZNF518ATGCTGSVA_HALLMARK_KRAS_SIGNALING_DNEAG5.4762e-030.3799image
chr10:96166465-96167619:+TGCTGSVA_HALLMARK_KRAS_SIGNALING_DNEER3.9452e-030.3931image
chr10:96165138-96165379:+THCAGSVA_HALLMARK_PROTEIN_SECRETIONEER3.0157e-020.4177image
ENSG00000177853.13,ZNF518ATHYMGSVA_HALLMARK_ALLOGRAFT_REJECTIONEAG2.5574e-03-0.4060image
chr10:96166465-96167619:+THYMGSVA_HALLMARK_ALLOGRAFT_REJECTIONEER3.2888e-03-0.3965image
chr10:96166465-96167619:+UCECGSVA_HALLMARK_ADIPOGENESISEER4.5038e-030.3267image
ENSG00000177853.13,ZNF518AUCECGSVA_HALLMARK_ADIPOGENESISEAG9.4972e-040.3670image


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7. Enriched editing regions and drugs for ZNF518A


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
chr10:96166465-96167619:+BLCAIPA.3EER3.8579e-040.2990image
ENSG00000177853.13,ZNF518ABLCAKIN001.135EAG1.1692e-03-0.2688image
chr10:96165138-96165379:+BLCABX.795EER4.4136e-02-0.3700image
ENSG00000177853.13,ZNF518ABRCAEpothilone.BEAG2.4510e-030.1224image
chr10:96166465-96167619:+BRCAGNF.2EER4.5992e-04-0.1449image
ENSG00000177853.13,ZNF518ACESCEmbelinEAG2.8372e-03-0.3672image
chr10:96166465-96167619:+CESCGefitinibEER1.4299e-03-0.3903image
chr10:96166465-96167619:+CHOLKIN001.135EER3.0997e-020.4158image
ENSG00000177853.13,ZNF518ACHOLKIN001.135EAG2.7610e-020.4238image
chr10:96166465-96167619:+COADAZ628EER1.3715e-030.2670image
chr10:96166465-96167619:+ESCABX.795EER1.0024e-02-0.2480image
chr10:96166465-96167619:+HNSCAG.014699EER4.1891e-020.3154image
chr10:96166465-96167619:+KICHCGP.082996EER8.1597e-030.5738image
ENSG00000177853.13,ZNF518AKICHBMS.536924EAG1.2347e-020.5356image
chr10:96166465-96167619:+KIRCImatinibEER2.9697e-030.2342image
ENSG00000177853.13,ZNF518AKIRCCCT007093EAG2.3693e-040.2833image
ENSG00000177853.13,ZNF518AKIRPBMS.708163EAG5.8437e-03-0.2600image
chr10:96166465-96167619:+KIRPBMS.708163EER5.2841e-03-0.2691image
ENSG00000177853.13,ZNF518ALAMLMethotrexateEAG1.8885e-020.2310image
chr10:96166465-96167619:+LAMLBIRB.0796EER9.8083e-04-0.4479image
ENSG00000177853.13,ZNF518ALGGJNK.9LEAG4.2337e-030.1765image
chr10:96166465-96167619:+LGGBosutinibEER1.4822e-030.1973image
ENSG00000177853.13,ZNF518ALUADGNF.2EAG3.2597e-03-0.2264image
chr10:96166465-96167619:+LUADLFM.A13EER5.5813e-03-0.2188image
chr10:96166465-96167619:+LUSCFTI.277EER1.6387e-02-0.2552image
ENSG00000177853.13,ZNF518ALUSCFTI.277EAG2.7818e-02-0.2332image
ENSG00000177853.13,ZNF518AOVFTI.277EAG5.9334e-03-0.2038image
chr10:96166465-96167619:+OVBortezomibEER1.9652e-02-0.1849image
chr10:96166465-96167619:+PAADDMOGEER1.8151e-02-0.2604image
ENSG00000177853.13,ZNF518APAADDMOGEAG1.3730e-02-0.2695image
ENSG00000177853.13,ZNF518APCPGGefitinibEAG1.5801e-02-0.3270image
chr10:96166465-96167619:+PCPGGefitinibEER1.6056e-02-0.3263image
ENSG00000177853.13,ZNF518APRADBIBW2992EAG4.5233e-03-0.1862image
chr10:96166465-96167619:+PRADBIBW2992EER7.3824e-03-0.1794image
chr10:96165138-96165379:+PRADDasatinibEER4.6880e-03-0.4382image
chr10:96166465-96167619:+SARCBMS.754807EER2.3880e-020.3812image
ENSG00000177853.13,ZNF518ASARCBMS.754807EAG2.2479e-020.3794image
ENSG00000177853.13,ZNF518ASKCMCisplatinEAG1.9023e-030.3340image
chr10:96166465-96167619:+SKCMCisplatinEER3.7391e-030.3130image
chr10:96150051-96150236:+STADAMG.706EER3.4023e-02-0.4254image
ENSG00000177853.13,ZNF518ASTADEmbelinEAG1.5093e-05-0.2478image
chr10:96166465-96167619:+STADGDC0941EER5.1158e-05-0.2508image
chr10:96166465-96167619:+TGCTLapatinibEER5.8675e-03-0.3770image
ENSG00000177853.13,ZNF518ATGCTLapatinibEAG5.0493e-03-0.3832image
ENSG00000177853.13,ZNF518ATHCAIPA.3EAG8.7967e-030.1916image
chr10:96166465-96167619:+THCAIPA.3EER2.7992e-020.1652image
ENSG00000177853.13,ZNF518ATHYMGW.441756EAG1.0747e-04-0.5069image
chr10:96166465-96167619:+THYMGW.441756EER1.9493e-04-0.4902image
ENSG00000177853.13,ZNF518AUCECAG.014699EAG2.9464e-040.3992image
chr10:96166465-96167619:+UCECAG.014699EER7.0901e-050.4451image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType