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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: NUMB (ImmuneEditome ID:8650)

1. Gene summary of enriched editing regions for NUMB

check button Gene summary
Gene informationGene symbol

NUMB

Gene ID

8650

GeneSynonymsC14orf41|S171|c14_5527
GeneCytomap

14q24.2-q24.3

GeneTypeprotein-coding
GeneDescriptionprotein numb homolog|h-Numb|numb homolog
GeneModificationdate20230329
UniprotIDA0A024R6C4;A0A024R684;P49757;A0A024R681;A0A024R6F4;G3V3R1;G3V3M5;G3V433;G3V4S6;G3V3Z8
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr14:73277631-73280970:-ENST00000355058.6ENSG00000133961.18NUMBexonicAluJo,AluSx,AluSc,AluSq2,AluSg,AluSc8,MIRbchr14:73277631-73280970:-.alignment
chr14:73277631-73280970:-ENST00000359560.6ENSG00000133961.18NUMBexonicAluJo,AluSx,AluSc,AluSq2,AluSg,AluSc8,MIRbchr14:73277631-73280970:-.alignment
chr14:73277631-73280970:-ENST00000555238.4ENSG00000133961.18NUMBexonicAluJo,AluSx,AluSc,AluSq2,AluSg,AluSc8,MIRbchr14:73277631-73280970:-.alignment
chr14:73277631-73280970:-ENST00000556772.4ENSG00000133961.18NUMBexonicAluJo,AluSx,AluSc,AluSq2,AluSg,AluSc8,MIRbchr14:73277631-73280970:-.alignment
chr14:73277631-73280970:-ENST00000557597.4ENSG00000133961.18NUMBexonicAluJo,AluSx,AluSc,AluSq2,AluSg,AluSc8,MIRbchr14:73277631-73280970:-.alignment
chr14:73284904-73286376:-ENST00000554014.5ENSG00000133961.18NUMBncRNA_exonicAluSq2,(T)n,AluJr4,AluSxchr14:73284904-73286376:-.alignment
chr14:73284904-73286376:-ENST00000554315.4ENSG00000133961.18NUMBncRNA_exonicAluSq2,(T)n,AluJr4,AluSxchr14:73284904-73286376:-.alignment
chr14:73284904-73286376:-ENST00000556989.1ENSG00000133961.18NUMBncRNA_exonicAluSq2,(T)n,AluJr4,AluSxchr14:73284904-73286376:-.alignment
chr14:73294552-73294743:-ENST00000554315.4ENSG00000133961.18NUMBncRNA_intronicAluSzchr14:73294552-73294743:-.alignment
chr14:73294552-73294743:-ENST00000556989.1ENSG00000133961.18NUMBncRNA_intronicAluSzchr14:73294552-73294743:-.alignment
chr14:73301494-73302593:-ENST00000554315.4ENSG00000133961.18NUMBncRNA_intronicAluSz,AluSx,AluJrchr14:73301494-73302593:-.alignment
chr14:73301494-73302593:-ENST00000556112.4ENSG00000133961.18NUMBncRNA_intronicAluSz,AluSx,AluJrchr14:73301494-73302593:-.alignment
chr14:73312233-73313257:-ENST00000554315.4ENSG00000133961.18NUMBncRNA_intronicTigger4,AluSz,AluJbchr14:73312233-73313257:-.alignment
chr14:73312233-73313257:-ENST00000556112.4ENSG00000133961.18NUMBncRNA_intronicTigger4,AluSz,AluJbchr14:73312233-73313257:-.alignment
chr14:73315975-73316187:-ENST00000554315.4ENSG00000133961.18NUMBncRNA_intronicAluSxchr14:73315975-73316187:-.alignment
chr14:73315975-73316187:-ENST00000556112.4ENSG00000133961.18NUMBncRNA_intronicAluSxchr14:73315975-73316187:-.alignment
chr14:73349894-73351399:-ENST00000554315.4ENSG00000133961.18NUMBncRNA_intronicL1PB4,A-rich,AluSx1,AluY,AluJb,AluSc,AluSz,(CA)n,L2a,(ACAT)nchr14:73349894-73351399:-.alignment
chr14:73349894-73351399:-ENST00000556112.4ENSG00000133961.18NUMBncRNA_intronicL1PB4,A-rich,AluSx1,AluY,AluJb,AluSc,AluSz,(CA)n,L2a,(ACAT)nchr14:73349894-73351399:-.alignment
chr14:73349894-73351399:-ENST00000557774.4ENSG00000133961.18NUMBncRNA_intronicL1PB4,A-rich,AluSx1,AluY,AluJb,AluSc,AluSz,(CA)n,L2a,(ACAT)nchr14:73349894-73351399:-.alignment
chr14:73352597-73354438:-ENST00000554315.4ENSG00000133961.18NUMBncRNA_intronicL2a,AluSz,L1ME4b,AluSx,AluSp,AluYchr14:73352597-73354438:-.alignment
chr14:73352597-73354438:-ENST00000556112.4ENSG00000133961.18NUMBncRNA_intronicL2a,AluSz,L1ME4b,AluSx,AluSp,AluYchr14:73352597-73354438:-.alignment
chr14:73352597-73354438:-ENST00000557774.4ENSG00000133961.18NUMBncRNA_intronicL2a,AluSz,L1ME4b,AluSx,AluSp,AluYchr14:73352597-73354438:-.alignment
chr14:73373958-73374945:-ENST00000554315.4ENSG00000133961.18NUMBncRNA_intronicAluJr4,AluSq2,L1M6chr14:73373958-73374945:-.alignment
chr14:73373958-73374945:-ENST00000556112.4ENSG00000133961.18NUMBncRNA_intronicAluJr4,AluSq2,L1M6chr14:73373958-73374945:-.alignment
chr14:73373958-73374945:-ENST00000556700.4ENSG00000133961.18NUMBncRNA_intronicAluJr4,AluSq2,L1M6chr14:73373958-73374945:-.alignment
chr14:73373958-73374945:-ENST00000557031.4ENSG00000133961.18NUMBncRNA_intronicAluJr4,AluSq2,L1M6chr14:73373958-73374945:-.alignment
chr14:73373958-73374945:-ENST00000557774.4ENSG00000133961.18NUMBncRNA_intronicAluJr4,AluSq2,L1M6chr14:73373958-73374945:-.alignment
chr14:73384180-73385458:-ENST00000554315.4ENSG00000133961.18NUMBncRNA_intronicAluSp,MER3,AluYm1,AluJo,L1MEg,(TTTG)n,AluJbchr14:73384180-73385458:-.alignment
chr14:73384180-73385458:-ENST00000556112.4ENSG00000133961.18NUMBncRNA_intronicAluSp,MER3,AluYm1,AluJo,L1MEg,(TTTG)n,AluJbchr14:73384180-73385458:-.alignment
chr14:73384180-73385458:-ENST00000556700.4ENSG00000133961.18NUMBncRNA_intronicAluSp,MER3,AluYm1,AluJo,L1MEg,(TTTG)n,AluJbchr14:73384180-73385458:-.alignment
chr14:73384180-73385458:-ENST00000557031.4ENSG00000133961.18NUMBncRNA_intronicAluSp,MER3,AluYm1,AluJo,L1MEg,(TTTG)n,AluJbchr14:73384180-73385458:-.alignment
chr14:73384180-73385458:-ENST00000557774.4ENSG00000133961.18NUMBncRNA_intronicAluSp,MER3,AluYm1,AluJo,L1MEg,(TTTG)n,AluJbchr14:73384180-73385458:-.alignment
chr14:73404780-73405624:-ENST00000554315.4ENSG00000133961.18NUMBncRNA_intronicFRAM,L1MC4a,L1MD2,AluSgchr14:73404780-73405624:-.alignment
chr14:73404780-73405624:-ENST00000556112.4ENSG00000133961.18NUMBncRNA_intronicFRAM,L1MC4a,L1MD2,AluSgchr14:73404780-73405624:-.alignment
chr14:73404780-73405624:-ENST00000556700.4ENSG00000133961.18NUMBncRNA_intronicFRAM,L1MC4a,L1MD2,AluSgchr14:73404780-73405624:-.alignment
chr14:73404780-73405624:-ENST00000557031.4ENSG00000133961.18NUMBncRNA_intronicFRAM,L1MC4a,L1MD2,AluSgchr14:73404780-73405624:-.alignment
chr14:73404780-73405624:-ENST00000557774.4ENSG00000133961.18NUMBncRNA_intronicFRAM,L1MC4a,L1MD2,AluSgchr14:73404780-73405624:-.alignment
chr14:73435363-73435595:-ENST00000553415.4ENSG00000133961.18NUMBncRNA_intronicAluY,L1M5chr14:73435363-73435595:-.alignment
chr14:73435363-73435595:-ENST00000554315.4ENSG00000133961.18NUMBncRNA_intronicAluY,L1M5chr14:73435363-73435595:-.alignment
chr14:73435363-73435595:-ENST00000556112.4ENSG00000133961.18NUMBncRNA_intronicAluY,L1M5chr14:73435363-73435595:-.alignment
chr14:73435363-73435595:-ENST00000556600.1ENSG00000133961.18NUMBncRNA_intronicAluY,L1M5chr14:73435363-73435595:-.alignment
chr14:73435363-73435595:-ENST00000556700.4ENSG00000133961.18NUMBncRNA_intronicAluY,L1M5chr14:73435363-73435595:-.alignment
chr14:73435363-73435595:-ENST00000557031.4ENSG00000133961.18NUMBncRNA_intronicAluY,L1M5chr14:73435363-73435595:-.alignment
chr14:73435363-73435595:-ENST00000557774.4ENSG00000133961.18NUMBncRNA_intronicAluY,L1M5chr14:73435363-73435595:-.alignment


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2. Tumor-specific enriched editing regions for NUMB


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
chr14:73373958-73374945:-STADPathEER1.7352e-024.9498e-020.3395image


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
chr14:73284904-73286376:-ESCAEER4.9242e-032.3419e-028.1587e-02image
chr14:73301494-73302593:-ESCAEER4.7317e-021.3992e-022.1012e+02image
ENSG00000133961.18,NUMBLAMLEAG6.9258e-034.4922e-022.7465e-02image

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3. Enriched editing regions and immune related genes for NUMB


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark

More results



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4. Enriched editing regions and immune related splicing for NUMB


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000133961.18,NUMB
ESCAEAGA5ENSG00000082014.12chr7151240424:151240522:151241491:151241653:151241163:151241653-0.27304.8080e-023.9739e-07-0.4730imageNACIN1;ADAR;AIFM1;CBX7;CELF2;CNBP;CSTF2T;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FUS;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPU;IGF2BP2;IGF2BP3;LARP4B;LIN28;METTL3;MOV10;MSI1;NOP56;NOP58;NUMA1;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RNF219;SF3B4;SRSF1;SRSF10;SRSF3;TAF15;TARDBP;TIA1;U2AF2;UPF1;VIM;YTHDC1;ZNF184NAGSVA_HALLMARK_PANCREAS_BETA_CELLS

More results



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5. Enriched editing regions and immune infiltration for NUMB


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
ENSG00000133961.18,NUMBBLCAEAGMacrophages_M01.9603e-020.4105image
chr14:73284904-73286376:-ESCAEERDendritic_cells_resting4.4931e-020.1882image
chr14:73435363-73435595:-ESCAEERNK_cells_activated3.0698e-020.4328image
ENSG00000133961.18,NUMBESCAEAGDendritic_cells_resting1.0316e-020.2201image
chr14:73284904-73286376:-KIRCEERNK_cells_resting3.8088e-030.3908image
ENSG00000133961.18,NUMBKIRCEAGNeutrophils1.0304e-02-0.2853image
chr14:73277631-73280970:-KIRPEERNeutrophils5.7056e-030.5576image
ENSG00000133961.18,NUMBKIRPEAGMonocytes1.2582e-040.4786image
ENSG00000133961.18,NUMBLAMLEAGDendritic_cells_activated5.6681e-030.2352image
chr14:73284904-73286376:-LUADEERT_cells_CD82.8027e-030.4140image
ENSG00000133961.18,NUMBLUADEAGT_cells_CD4_memory_resting5.3479e-03-0.3031image
chr14:73277631-73280970:-OVEEREosinophils1.1742e-050.4152image
chr14:73284904-73286376:-OVEERNeutrophils3.7112e-02-0.2768image
ENSG00000133961.18,NUMBOVEAGEosinophils1.1494e-030.2982image
ENSG00000133961.18,NUMBPAADEAGT_cells_CD82.3834e-030.6018image
ENSG00000133961.18,NUMBPRADEAGT_cells_regulatory_(Tregs)1.5531e-02-0.5091image
chr14:73277631-73280970:-STADEERT_cells_CD4_memory_activated7.1125e-030.1852image
chr14:73284904-73286376:-STADEERMonocytes1.6168e-02-0.1791image
chr14:73301494-73302593:-STADEERNK_cells_resting1.2250e-020.2789image
chr14:73349894-73351399:-STADEERT_cells_regulatory_(Tregs)3.1733e-020.3105image
chr14:73352597-73354438:-STADEERPlasma_cells3.7292e-02-0.2151image
chr14:73384180-73385458:-STADEERNeutrophils1.3917e-02-0.3109image
chr14:73404780-73405624:-STADEERT_cells_CD81.3169e-030.5861image
ENSG00000133961.18,NUMBSTADEAGT_cells_CD4_memory_activated2.1251e-020.1468image
chr14:73277631-73280970:-THCAEERT_cells_gamma_delta5.5642e-030.5377image
ENSG00000133961.18,NUMBTHCAEAGPlasma_cells4.1941e-020.3080image


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6. Enriched editing regions and immune gene sets for NUMB


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot
chr14:73277631-73280970:-STADEER6.7357e-030.18641.7387e-030.21483.0395e-020.14947.7494e-030.1833image


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
ENSG00000133961.18,NUMBBLCAGSVA_HALLMARK_COAGULATIONEAG6.2832e-030.4728image
ENSG00000133961.18,NUMBBRCAGSVA_HALLMARK_APICAL_SURFACEEAG1.8067e-030.3356image
chr14:73277631-73280970:-BRCAGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEER3.6695e-020.3159image
chr14:73435363-73435595:-ESCAGSVA_HALLMARK_MYC_TARGETS_V2EER4.3819e-020.4064image
chr14:73277631-73280970:-ESCAGSVA_HALLMARK_UV_RESPONSE_UPEER1.2092e-020.2418image
chr14:73384180-73385458:-ESCAGSVA_HALLMARK_P53_PATHWAYEER5.3364e-030.4488image
chr14:73277631-73280970:-KIRCGSVA_HALLMARK_KRAS_SIGNALING_DNEER3.5699e-020.3331image
ENSG00000133961.18,NUMBKIRCGSVA_HALLMARK_KRAS_SIGNALING_DNEAG6.6248e-030.3012image
chr14:73284904-73286376:-KIRCGSVA_HALLMARK_KRAS_SIGNALING_DNEER4.8902e-020.2719image
ENSG00000133961.18,NUMBKIRPGSVA_HALLMARK_GLYCOLYSISEAG1.2924e-020.3219image
chr14:73277631-73280970:-KIRPGSVA_HALLMARK_KRAS_SIGNALING_DNEER2.1746e-02-0.4758image
ENSG00000133961.18,NUMBLAMLGSVA_HALLMARK_MITOTIC_SPINDLEEAG4.0764e-020.1750image
ENSG00000133961.18,NUMBLUADGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEAG5.2890e-050.4286image
chr14:73277631-73280970:-LUADGSVA_HALLMARK_PANCREAS_BETA_CELLSEER4.2443e-030.4535image
chr14:73284904-73286376:-LUADGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEER1.8899e-030.4288image
chr14:73284904-73286376:-OVGSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALINGEER1.1205e-02-0.3336image
ENSG00000133961.18,NUMBPRADGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG1.5990e-02-0.5072image
chr14:73277631-73280970:-STADGSVA_HALLMARK_MITOTIC_SPINDLEEER3.9109e-050.2798image
chr14:73384180-73385458:-STADGSVA_HALLMARK_MYOGENESISEER1.6957e-02-0.3022image
chr14:73301494-73302593:-STADGSVA_HALLMARK_DNA_REPAIREER2.2663e-03-0.3366image
chr14:73284904-73286376:-STADGSVA_HALLMARK_DNA_REPAIREER4.6183e-040.2584image
chr14:73312233-73313257:-STADGSVA_HALLMARK_SPERMATOGENESISEER2.6369e-020.2776image
ENSG00000133961.18,NUMBSTADGSVA_HALLMARK_MITOTIC_SPINDLEEAG5.9946e-050.2530image
ENSG00000133961.18,NUMBTHCAGSVA_HALLMARK_PANCREAS_BETA_CELLSEAG4.1014e-020.3094image
ENSG00000133961.18,NUMBUCECGSVA_HALLMARK_UV_RESPONSE_UPEAG3.4182e-030.5526image


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7. Enriched editing regions and drugs for NUMB


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
ENSG00000133961.18,NUMBBLCABicalutamideEAG7.0367e-03-0.4671image
ENSG00000133961.18,NUMBBRCALenalidomideEAG1.7663e-020.2583image
chr14:73277631-73280970:-BRCACCT018159EER1.3142e-020.3711image
ENSG00000133961.18,NUMBCESCEHT.1864EAG2.1180e-020.4123image
chr14:73435363-73435595:-ESCAABT.263EER4.2108e-020.4180image
chr14:73284904-73286376:-ESCACisplatinEER2.1917e-03-0.2841image
ENSG00000133961.18,NUMBESCAErlotinibEAG4.2570e-02-0.1748image
chr14:73301494-73302593:-ESCAABT.888EER4.5521e-03-0.4110image
chr14:73384180-73385458:-ESCAEpothilone.BEER2.1370e-03-0.4889image
chr14:73277631-73280970:-ESCAABT.263EER3.9757e-030.2775image
ENSG00000133961.18,NUMBKIRCCI.1040EAG4.5015e-02-0.2248image
chr14:73284904-73286376:-KIRCGDC.0449EER1.4224e-02-0.3349image
chr14:73277631-73280970:-KIRCCI.1040EER2.1470e-03-0.4712image
ENSG00000133961.18,NUMBKIRPIPA.3EAG1.3343e-020.3205image
chr14:73277631-73280970:-KIRPBMS.754807EER3.3863e-020.4439image
ENSG00000133961.18,NUMBLAMLCCT018159EAG2.7246e-03-0.2542image
ENSG00000133961.18,NUMBLUADBAY.61.3606EAG5.2380e-040.3725image
chr14:73284904-73286376:-LUADMethotrexateEER1.0763e-030.4489image
chr14:73277631-73280970:-LUADBosutinibEER9.0025e-030.4181image
chr14:73284904-73286376:-OVBryostatin.1EER3.7935e-02-0.2757image
ENSG00000133961.18,NUMBOVFTI.277EAG4.7000e-03-0.2607image
chr14:73277631-73280970:-OVBryostatin.1EER2.5814e-02-0.2186image
ENSG00000133961.18,NUMBPAADCisplatinEAG1.1102e-02-0.5193image
ENSG00000133961.18,NUMBPRADAZ628EAG1.1937e-020.5377image
chr14:73277631-73280970:-STADBMS.708163EER2.0680e-020.1596image
chr14:73284904-73286376:-STADCCT007093EER6.5462e-030.2020image
ENSG00000133961.18,NUMBSTADBMS.708163EAG1.4291e-030.2022image
chr14:73404780-73405624:-STADBleomycinEER2.4830e-02-0.4309image
chr14:73301494-73302593:-STADAS601245EER2.6970e-03-0.3311image
chr14:73384180-73385458:-STADCGP.60474EER6.2505e-050.4859image
chr14:73435363-73435595:-STADMG.132EER1.3997e-05-0.6043image
ENSG00000133961.18,NUMBTHCACI.1040EAG6.5405e-03-0.4040image
chr14:73277631-73280970:-THCACisplatinEER4.8575e-03-0.5449image
ENSG00000133961.18,NUMBUCECAZD7762EAG1.5184e-03-0.5898image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType