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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: GTPBP10 (ImmuneEditome ID:85865)

1. Gene summary of enriched editing regions for GTPBP10

check button Gene summary
Gene informationGene symbol

GTPBP10

Gene ID

85865

GeneSynonymsObgH2|UG0751c10
GeneCytomap

7q21.13

GeneTypeprotein-coding
GeneDescriptionGTP-binding protein 10|GTP binding protein 10 (putative)|protein obg homolog 2
GeneModificationdate20230329
UniprotIDA4D1E9;C9J8R7;F8WCN4;F8WBB5;F8WBY0;C9JNI1;C9JEQ8
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr7:90358324-90359033:+ENST00000474503.1ENSG00000105793.14GTPBP10ncRNA_intronicL1PB3chr7:90358324-90359033:+.alignment
chr7:90370122-90370799:+ENST00000474503.1ENSG00000105793.14GTPBP10ncRNA_intronicAluY,L1PB3chr7:90370122-90370799:+.alignment
chr7:90385857-90387264:+ENST00000222511.9ENSG00000105793.14GTPBP10UTR3(TATTT)n,FLAM_C,AluSzchr7:90385857-90387264:+.alignment
chr7:90385857-90387264:+ENST00000257659.11ENSG00000105793.14GTPBP10UTR3(TATTT)n,FLAM_C,AluSzchr7:90385857-90387264:+.alignment
chr7:90385857-90387264:+ENST00000380058.6ENSG00000105793.14GTPBP10UTR3(TATTT)n,FLAM_C,AluSzchr7:90385857-90387264:+.alignment
chr7:90389402-90390108:+ENST00000222511.9ENSG00000105793.14GTPBP10UTR3AluSc5,AluJr4chr7:90389402-90390108:+.alignment
chr7:90389402-90390108:+ENST00000380058.6ENSG00000105793.14GTPBP10UTR3AluSc5,AluJr4chr7:90389402-90390108:+.alignment


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2. Tumor-specific enriched editing regions for GTPBP10


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chr7:90389402-90390108:+BRCAEER2.9011e-06image
ENSG00000105793.14,GTPBP10BRCAEAG3.6022e-04image
ENSG00000105793.14,GTPBP10HNSCEAG7.6057e-03image
chr7:90389402-90390108:+KICHEER1.8301e-02image
ENSG00000105793.14,GTPBP10KIRCEAG4.3255e-02image
chr7:90389402-90390108:+LUSCEER3.0720e-02image
ENSG00000105793.14,GTPBP10LUSCEAG3.7168e-02image
chr7:90389402-90390108:+PRADEER1.9194e-02image
chr7:90389402-90390108:+THCAEER2.8306e-06image
ENSG00000105793.14,GTPBP10THCAEAG1.5949e-07image


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
chr7:90389402-90390108:+BRCAPathEER1.0397e-024.5232e-020.0642image
ENSG00000105793.14,GTPBP10THCAPathEAG3.0123e-034.3073e-040.1621image
chr7:90389402-90390108:+THCAPathEER1.3137e-035.1726e-040.1602image


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
chr7:90389402-90390108:+OVEER1.9074e-022.9044e-024.2188e+00image

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3. Enriched editing regions and immune related genes for GTPBP10


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr7:90389402-90390108:+KICHEERENSG00000255480,RP4-710M3.2-0.55013.0967e-027.8305e-04-0.4324imageNNNAMacrophages_M0GSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr7:90389402-90390108:+KIRPEERENSG00000110375,UPK20.23853.5611e-035.5867e-130.4601imageNNNAT_cells_CD4_naiveGSVA_HALLMARK_PANCREAS_BETA_CELLS
chr7:90389402-90390108:+KIRPEERENSG00000133056,PIK3C2B0.23066.1815e-034.8089e-110.4238imageNEIF4A3;IGF2BP2NADendritic_cells_activatedGSVA_HALLMARK_MITOTIC_SPINDLE
chr7:90389402-90390108:+KIRPEERENSG00000180776,ZDHHC200.21111.3817e-023.8733e-150.4962imageNEIF4A3;IGF2BP2NADendritic_cells_activatedGSVA_HALLMARK_G2M_CHECKPOINT
chr7:90389402-90390108:+KIRPEERENSG00000105357,MYH140.20521.5549e-025.2855e-100.4023imageNEIF4A3;IGF2BP2NADendritic_cells_activatedGSVA_HALLMARK_MITOTIC_SPINDLE
chr7:90389402-90390108:+KIRPEERENSG00000115884,SDC10.20981.6446e-022.6813e-130.4657imageNEIF4A3;IGF2BP2SDC1Dendritic_cells_activatedGSVA_HALLMARK_MYC_TARGETS_V2
chr7:90389402-90390108:+KIRPEERENSG00000160685,ZBTB7B0.21051.7087e-021.4025e-100.4144imageNEIF4A3;IGF2BP2NAMacrophages_M0GSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr7:90389402-90390108:+KIRPEERENSG00000178363,CALML30.19191.9903e-024.0840e-110.4252imageNNNADendritic_cells_activatedGSVA_HALLMARK_G2M_CHECKPOINT
chr7:90389402-90390108:+KIRPEERENSG00000138413,IDH10.19782.3234e-021.9628e-120.4503imageNEIF4A3;IGF2BP2NADendritic_cells_activatedGSVA_HALLMARK_MTORC1_SIGNALING
chr7:90389402-90390108:+KIRPEERENSG00000197312,DDI20.19722.5702e-021.6336e-140.4862imageNEIF4A3;IGF2BP2NADendritic_cells_activatedGSVA_HALLMARK_MITOTIC_SPINDLE
chr7:90389402-90390108:+KICHEERENSG00000255480,RP4-710M3.2-0.55013.0967e-027.8305e-04-0.4324imageNNNAMacrophages_M0GSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr7:90389402-90390108:+KIRPEERENSG00000110375,UPK20.23853.5611e-035.5867e-130.4601imageNNNAT_cells_CD4_naiveGSVA_HALLMARK_PANCREAS_BETA_CELLS
chr7:90389402-90390108:+KIRPEERENSG00000133056,PIK3C2B0.23066.1815e-034.8089e-110.4238imageNEIF4A3;IGF2BP2NADendritic_cells_activatedGSVA_HALLMARK_MITOTIC_SPINDLE
chr7:90389402-90390108:+KIRPEERENSG00000180776,ZDHHC200.21111.3817e-023.8733e-150.4962imageNEIF4A3;IGF2BP2NADendritic_cells_activatedGSVA_HALLMARK_G2M_CHECKPOINT
chr7:90389402-90390108:+KIRPEERENSG00000105357,MYH140.20521.5549e-025.2855e-100.4023imageNEIF4A3;IGF2BP2NADendritic_cells_activatedGSVA_HALLMARK_MITOTIC_SPINDLE
chr7:90389402-90390108:+KIRPEERENSG00000115884,SDC10.20981.6446e-022.6813e-130.4657imageNEIF4A3;IGF2BP2SDC1Dendritic_cells_activatedGSVA_HALLMARK_MYC_TARGETS_V2
chr7:90389402-90390108:+KIRPEERENSG00000160685,ZBTB7B0.21051.7087e-021.4025e-100.4144imageNEIF4A3;IGF2BP2NAMacrophages_M0GSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr7:90389402-90390108:+KIRPEERENSG00000178363,CALML30.19191.9903e-024.0840e-110.4252imageNNNADendritic_cells_activatedGSVA_HALLMARK_G2M_CHECKPOINT
chr7:90389402-90390108:+KIRPEERENSG00000138413,IDH10.19782.3234e-021.9628e-120.4503imageNEIF4A3;IGF2BP2NADendritic_cells_activatedGSVA_HALLMARK_MTORC1_SIGNALING
chr7:90389402-90390108:+KIRPEERENSG00000197312,DDI20.19722.5702e-021.6336e-140.4862imageNEIF4A3;IGF2BP2NADendritic_cells_activatedGSVA_HALLMARK_MITOTIC_SPINDLE

More results



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4. Enriched editing regions and immune related splicing for GTPBP10


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000105793.14,GTPBP10
CESCEAGMEXENSG00000129657.10chr1777215922:77215935:77216023:77216088:77216205:77216244:77216322:77216335-0.17341.2786e-029.6374e-09-0.4342imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NADendritic_cells_resting
ENSG00000105793.14,GTPBP10
CESCEAGMEXENSG00000129657.10chr1777215922:77215935:77216023:77216127:77216205:77216244:77216322:77216335-0.16532.0426e-029.1802e-09-0.4386imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NADendritic_cells_resting
ENSG00000105793.14,GTPBP10
CESCEAGMEXENSG00000129657.10chr1777215922:77215935:77216023:77216114:77216114:77216244:77216322:77216335-0.15652.4310e-022.2079e-08-0.4245imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NADendritic_cells_activatedGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKB
ENSG00000105793.14,GTPBP10
CESCEAGMEXENSG00000129657.10chr1777215922:77215935:77216023:77216049:77216114:77216244:77216322:77216335-0.15762.4461e-021.2277e-08-0.4327imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NADendritic_cells_resting
ENSG00000105793.14,GTPBP10
CESCEAGMEXENSG00000129657.10chr1777215922:77215935:77216023:77216127:77216192:77216244:77216322:77216335-0.16222.5235e-021.0878e-07-0.4085imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NADendritic_cells_activatedGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKB
ENSG00000105793.14,GTPBP10
CESCEAGMEXENSG00000129657.10chr1777215922:77215935:77216023:77216114:77216192:77216244:77216322:77216335-0.16192.6773e-021.5460e-07-0.4005imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NADendritic_cells_activatedGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKB
ENSG00000105793.14,GTPBP10
CESCEAGMEXENSG00000129657.10chr1777215922:77215935:77216023:77216192:77216205:77216244:77216322:77216335-0.16303.0293e-022.7128e-08-0.4209imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NADendritic_cells_resting
ENSG00000105793.14,GTPBP10
CESCEAGMEXENSG00000129657.10chr1777215922:77215935:77216023:77216049:77216062:77216244:77216322:77216335-0.15633.4567e-024.4898e-08-0.4172imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NADendritic_cells_resting
ENSG00000105793.14,GTPBP10
CESCEAGMEXENSG00000129657.10chr1777215922:77215935:77216023:77216127:77216127:77216244:77216322:77216335-0.15283.7021e-021.6288e-08-0.4319imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NADendritic_cells_activatedGSVA_HALLMARK_ADIPOGENESIS
ENSG00000105793.14,GTPBP10
CESCEAGMEXENSG00000129657.10chr1777215922:77215935:77216023:77216049:77216127:77216244:77216322:77216335-0.15433.7399e-021.3080e-08-0.4319imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NADendritic_cells_restingGSVA_HALLMARK_ADIPOGENESIS

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5. Enriched editing regions and immune infiltration for GTPBP10


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chr7:90389402-90390108:+BLCAEERT_cells_follicular_helper3.4352e-02-0.1461image
ENSG00000105793.14,GTPBP10BLCAEAGDendritic_cells_resting1.2874e-02-0.1663image
chr7:90385857-90387264:+BRCAEERT_cells_CD83.9422e-03-0.1202image
chr7:90389402-90390108:+BRCAEERNK_cells_activated2.9607e-03-0.0949image
ENSG00000105793.14,GTPBP10BRCAEAGT_cells_CD4_memory_resting1.7217e-08-0.1774image
chr7:90389402-90390108:+CESCEERNK_cells_resting1.0701e-020.1750image
ENSG00000105793.14,GTPBP10CESCEAGT_cells_CD81.8234e-020.1594image
chr7:90389402-90390108:+CHOLEERT_cells_CD4_memory_resting4.3699e-02-0.4151image
ENSG00000105793.14,GTPBP10CHOLEAGT_cells_CD4_memory_resting7.1241e-03-0.5244image
chr7:90389402-90390108:+COADEERNeutrophils5.9336e-040.2192image
ENSG00000105793.14,GTPBP10COADEAGEosinophils2.2200e-03-0.1900image
ENSG00000105793.14,GTPBP10DLBCEAGMacrophages_M24.7640e-020.3920image
chr7:90389402-90390108:+ESCAEERT_cells_CD4_memory_resting1.3527e-03-0.2585image
ENSG00000105793.14,GTPBP10ESCAEAGT_cells_CD4_memory_resting3.9015e-04-0.2788image
chr7:90389402-90390108:+GBMEERMonocytes5.5623e-040.2786image
ENSG00000105793.14,GTPBP10GBMEAGPlasma_cells1.0724e-030.2645image
chr7:90389402-90390108:+HNSCEERMast_cells_activated1.0636e-03-0.2122image
ENSG00000105793.14,GTPBP10HNSCEAGT_cells_CD4_memory_resting8.0811e-03-0.1624image
chr7:90389402-90390108:+KICHEERT_cells_regulatory_(Tregs)1.1918e-02-0.3309image
chr7:90389402-90390108:+KIRCEERT_cells_CD84.3395e-020.1197image
ENSG00000105793.14,GTPBP10KIRCEAGT_cells_CD81.6167e-020.1392image
chr7:90389402-90390108:+KIRPEERT_cells_CD4_naive5.1891e-050.2687image
ENSG00000105793.14,GTPBP10KIRPEAGT_cells_CD4_naive1.0420e-050.2892image
chr7:90358324-90359033:+LAMLEERT_cells_follicular_helper1.7750e-020.3077image
ENSG00000105793.14,GTPBP10LAMLEAGMast_cells_activated4.0348e-020.2216image
chr7:90389402-90390108:+LGGEERMonocytes5.1736e-030.1273image
ENSG00000105793.14,GTPBP10LGGEAGMonocytes1.3407e-030.1445image
chr7:90389402-90390108:+LIHCEERT_cells_CD81.6404e-020.1674image
ENSG00000105793.14,GTPBP10LIHCEAGPlasma_cells2.5689e-030.2056image
chr7:90389402-90390108:+LUADEERMast_cells_activated3.9544e-060.2671image
ENSG00000105793.14,GTPBP10LUADEAGT_cells_CD4_memory_resting4.9066e-05-0.2226image
chr7:90389402-90390108:+LUSCEERMacrophages_M04.7772e-03-0.1579image
ENSG00000105793.14,GTPBP10LUSCEAGB_cells_naive2.9620e-02-0.1180image
chr7:90389402-90390108:+OVEERNK_cells_activated4.0763e-030.1759image
chr7:90389402-90390108:+PAADEERMacrophages_M01.6795e-020.2286image
ENSG00000105793.14,GTPBP10PAADEAGT_cells_CD4_memory_resting9.5965e-03-0.2416image
chr7:90389402-90390108:+PCPGEERMonocytes1.0637e-020.2315image
ENSG00000105793.14,GTPBP10PCPGEAGNK_cells_activated3.9687e-030.2520image
chr7:90389402-90390108:+PRADEERT_cells_regulatory_(Tregs)1.1430e-050.2075image
ENSG00000105793.14,GTPBP10PRADEAGT_cells_regulatory_(Tregs)1.1006e-040.1817image
chr7:90389402-90390108:+SARCEERT_cells_follicular_helper8.8339e-040.2653image
ENSG00000105793.14,GTPBP10SARCEAGT_cells_follicular_helper1.2761e-030.2502image
chr7:90389402-90390108:+SKCMEERMacrophages_M12.6049e-030.1759image
ENSG00000105793.14,GTPBP10SKCMEAGMast_cells_resting9.6980e-03-0.1486image
chr7:90389402-90390108:+STADEERT_cells_CD4_memory_activated1.1125e-020.1431image
ENSG00000105793.14,GTPBP10STADEAGT_cells_CD4_memory_activated1.7012e-030.1691image
chr7:90389402-90390108:+TGCTEERB_cells_naive3.4307e-040.3228image
ENSG00000105793.14,GTPBP10TGCTEAGMacrophages_M21.5159e-02-0.2203image
chr7:90389402-90390108:+THCAEERT_cells_CD86.5384e-03-0.1256image
ENSG00000105793.14,GTPBP10THCAEAGMacrophages_M03.0639e-020.0997image
chr7:90389402-90390108:+THYMEERMacrophages_M19.9041e-030.2417image
ENSG00000105793.14,GTPBP10THYMEAGMacrophages_M12.5442e-020.2102image
chr7:90389402-90390108:+UCECEERDendritic_cells_activated5.3374e-060.3989image
ENSG00000105793.14,GTPBP10UCECEAGDendritic_cells_activated2.7118e-040.3154image
chr7:90389402-90390108:+UCSEERMacrophages_M08.9368e-040.5365image
ENSG00000105793.14,GTPBP10UCSEAGMacrophages_M08.2050e-040.5200image
chr7:90389402-90390108:+UVMEERB_cells_naive2.1552e-020.4666image


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6. Enriched editing regions and immune gene sets for GTPBP10


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot
chr7:90389402-90390108:+LUSCEER1.2304e-02image1.6980e-020.1338image


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot
ENSG00000105793.14,GTPBP10BRCAEAG3.9986e-100.19641.9666e-050.13478.3080e-070.15536.9391e-030.0854image
chr7:90389402-90390108:+PAADEER4.6255e-020.19135.2909e-030.26543.7126e-020.19994.0653e-020.1964image


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
ENSG00000105793.14,GTPBP10ACCGSVA_HALLMARK_ANDROGEN_RESPONSEEAG7.8873e-04-0.4357image
chr7:90389402-90390108:+ACCGSVA_HALLMARK_ANDROGEN_RESPONSEEER2.2084e-03-0.4078image
ENSG00000105793.14,GTPBP10BLCAGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG1.4193e-020.1640image
chr7:90389402-90390108:+BLCAGSVA_HALLMARK_MTORC1_SIGNALINGEER8.3894e-040.2288image
chr7:90389402-90390108:+BRCAGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER7.1927e-140.2361image
ENSG00000105793.14,GTPBP10BRCAGSVA_HALLMARK_UV_RESPONSE_UPEAG1.1083e-140.2414image
chr7:90385857-90387264:+BRCAGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEER5.5700e-050.1675image
chr7:90389402-90390108:+CESCGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER2.5221e-040.2489image
ENSG00000105793.14,GTPBP10CESCGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG1.5199e-040.2532image
chr7:90389402-90390108:+CHOLGSVA_HALLMARK_MITOTIC_SPINDLEEER2.2741e-020.4629image
ENSG00000105793.14,GTPBP10CHOLGSVA_HALLMARK_KRAS_SIGNALING_DNEAG1.4474e-02-0.4829image
chr7:90389402-90390108:+COADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER6.3879e-050.2541image
ENSG00000105793.14,GTPBP10COADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG3.1236e-060.2861image
ENSG00000105793.14,GTPBP10DLBCGSVA_HALLMARK_COAGULATIONEAG3.0140e-020.4257image
chr7:90389402-90390108:+DLBCGSVA_HALLMARK_ADIPOGENESISEER3.9166e-030.5663image
ENSG00000105793.14,GTPBP10ESCAGSVA_HALLMARK_P53_PATHWAYEAG1.5717e-020.1919image
chr7:90389402-90390108:+ESCAGSVA_HALLMARK_HYPOXIAEER8.7939e-040.2680image
chr7:90389402-90390108:+GBMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.3261e-020.2018image
ENSG00000105793.14,GTPBP10GBMGSVA_HALLMARK_MYC_TARGETS_V2EAG7.3839e-03-0.2179image
chr7:90389402-90390108:+HNSCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER3.3918e-040.2318image
ENSG00000105793.14,GTPBP10HNSCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG5.7060e-030.1694image
chr7:90389402-90390108:+KICHGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER7.8510e-030.3487image
ENSG00000105793.14,GTPBP10KICHGSVA_HALLMARK_MYC_TARGETS_V1EAG4.1289e-03-0.3711image
chr7:90389402-90390108:+KIRCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER2.0028e-020.1377image
chr7:90389402-90390108:+KIRPGSVA_HALLMARK_E2F_TARGETSEER2.2526e-030.2045image
ENSG00000105793.14,GTPBP10KIRPGSVA_HALLMARK_MYC_TARGETS_V2EAG4.1981e-020.1357image
chr7:90389402-90390108:+LGGGSVA_HALLMARK_MYC_TARGETS_V2EER7.7839e-03-0.1212image
ENSG00000105793.14,GTPBP10LGGGSVA_HALLMARK_PROTEIN_SECRETIONEAG9.3561e-04-0.1490image
ENSG00000105793.14,GTPBP10LIHCGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG1.7542e-030.2132image
chr7:90389402-90390108:+LIHCGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER4.5999e-030.1972image
ENSG00000105793.14,GTPBP10LUADGSVA_HALLMARK_UV_RESPONSE_UPEAG1.2242e-040.2108image
chr7:90389402-90390108:+LUADGSVA_HALLMARK_UV_RESPONSE_UPEER8.9671e-050.2280image
ENSG00000105793.14,GTPBP10LUSCGSVA_HALLMARK_ALLOGRAFT_REJECTIONEAG4.4945e-030.1537image
chr7:90389402-90390108:+LUSCGSVA_HALLMARK_ALLOGRAFT_REJECTIONEER1.7622e-070.2878image
chr7:90389402-90390108:+MESOGSVA_HALLMARK_KRAS_SIGNALING_DNEER2.7476e-020.3216image
chr7:90389402-90390108:+OVGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER8.4957e-030.1614image
chr7:90389402-90390108:+PAADGSVA_HALLMARK_MTORC1_SIGNALINGEER1.2999e-030.3042image
ENSG00000105793.14,GTPBP10PAADGSVA_HALLMARK_DNA_REPAIREAG3.2322e-030.2735image
ENSG00000105793.14,GTPBP10PCPGGSVA_HALLMARK_HEME_METABOLISMEAG1.5998e-020.2118image
chr7:90389402-90390108:+PCPGGSVA_HALLMARK_PROTEIN_SECRETIONEER2.2884e-030.2748image
chr7:90389402-90390108:+PRADGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER5.9312e-050.1902image
ENSG00000105793.14,GTPBP10PRADGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG2.5090e-030.1425image
chr7:90389402-90390108:+READGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.6935e-020.2540image
ENSG00000105793.14,GTPBP10READGSVA_HALLMARK_XENOBIOTIC_METABOLISMEAG9.4173e-03-0.2708image
chr7:90389402-90390108:+SARCGSVA_HALLMARK_PEROXISOMEEER9.8537e-040.2630image
ENSG00000105793.14,GTPBP10SARCGSVA_HALLMARK_PEROXISOMEEAG1.0964e-040.2984image
chr7:90389402-90390108:+SKCMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER9.0754e-050.2274image
ENSG00000105793.14,GTPBP10SKCMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG6.3464e-040.1955image
chr7:90389402-90390108:+STADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER6.3496e-030.1537image
ENSG00000105793.14,GTPBP10STADGSVA_HALLMARK_HEDGEHOG_SIGNALINGEAG7.5000e-04-0.1814image
ENSG00000105793.14,GTPBP10TGCTGSVA_HALLMARK_PANCREAS_BETA_CELLSEAG2.6168e-02-0.2022image
chr7:90389402-90390108:+TGCTGSVA_HALLMARK_MITOTIC_SPINDLEEER1.9758e-050.3804image
ENSG00000105793.14,GTPBP10THCAGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEAG9.0516e-080.2435image
chr7:90389402-90390108:+THCAGSVA_HALLMARK_APOPTOSISEER2.2928e-070.2364image
ENSG00000105793.14,GTPBP10THYMGSVA_HALLMARK_APOPTOSISEAG5.9253e-030.2574image
chr7:90389402-90390108:+THYMGSVA_HALLMARK_PROTEIN_SECRETIONEER8.5884e-040.3093image
chr7:90389402-90390108:+UCECGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.2130e-020.2265image
ENSG00000105793.14,GTPBP10UCECGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG2.0533e-020.2038image
ENSG00000105793.14,GTPBP10UCSGSVA_HALLMARK_HYPOXIAEAG2.7291e-020.3581image
chr7:90389402-90390108:+UCSGSVA_HALLMARK_HYPOXIAEER2.3804e-020.3813image


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7. Enriched editing regions and drugs for GTPBP10


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
ENSG00000105793.14,GTPBP10ACCLenalidomideEAG1.2603e-02-0.3314image
chr7:90389402-90390108:+ACCLenalidomideEER1.6236e-02-0.3257image
chr7:90389402-90390108:+BLCAAICAREER4.8154e-03-0.1938image
ENSG00000105793.14,GTPBP10BLCACGP.60474EAG2.9897e-03-0.1979image
chr7:90389402-90390108:+BRCACGP.082996EER7.1483e-07-0.1576image
ENSG00000105793.14,GTPBP10BRCACCT007093EAG1.3143e-090.1906image
chr7:90385857-90387264:+BRCAGNF.2EER1.9227e-05-0.1775image
ENSG00000105793.14,GTPBP10CESCBIRB.0796EAG1.2102e-03-0.2173image
chr7:90389402-90390108:+CESCDoxorubicinEER3.1359e-03-0.2020image
chr7:90389402-90390108:+CHOLBMS.536924EER7.6407e-030.5306image
chr7:90389402-90390108:+COADGefitinibEER1.4471e-03-0.2036image
ENSG00000105793.14,GTPBP10COADBortezomibEAG4.6060e-06-0.2814image
ENSG00000105793.14,GTPBP10DLBCAZD8055EAG2.5565e-03-0.5664image
chr7:90389402-90390108:+DLBCAZD8055EER1.1032e-03-0.6246image
ENSG00000105793.14,GTPBP10ESCAAUY922EAG1.1602e-03-0.2561image
chr7:90370122-90370799:+ESCABleomycinEER5.6516e-03-0.4350image
chr7:90389402-90390108:+ESCABI.D1870EER9.0387e-04-0.2674image
chr7:90389402-90390108:+GBMBMS.754807EER1.5626e-030.2561image
ENSG00000105793.14,GTPBP10GBMCGP.082996EAG1.6605e-04-0.3028image
chr7:90389402-90390108:+HNSCCytarabineEER6.0680e-030.1785image
ENSG00000105793.14,GTPBP10HNSCBIRB.0796EAG1.1069e-02-0.1558image
chr7:90389402-90390108:+KICHErlotinibEER6.9469e-05-0.5020image
ENSG00000105793.14,GTPBP10KICHGNF.2EAG5.5579e-05-0.5037image
ENSG00000105793.14,GTPBP10KIRCBMS.536924EAG2.5541e-03-0.1744image
chr7:90389402-90390108:+KIRCAZD8055EER2.0135e-02-0.1376image
chr7:90389402-90390108:+KIRPAS601245EER1.5065e-040.2522image
ENSG00000105793.14,GTPBP10KIRPAS601245EAG3.2860e-040.2373image
ENSG00000105793.14,GTPBP10LAMLBMS.536924EAG4.2274e-02-0.2195image
chr7:90358324-90359033:+LAMLFTI.277EER2.2064e-020.2976image
ENSG00000105793.14,GTPBP10LGGAG.014699EAG4.1901e-03-0.1291image
chr7:90389402-90390108:+LGGAG.014699EER8.7886e-04-0.1512image
chr7:90389402-90390108:+LIHCErlotinibEER1.7854e-02-0.1779image
ENSG00000105793.14,GTPBP10LIHCErlotinibEAG6.9561e-03-0.1978image
chr7:90389402-90390108:+LUADCCT018159EER1.0502e-02-0.1501image
ENSG00000105793.14,GTPBP10LUADBMS.509744EAG5.9162e-04-0.1890image
chr7:90389402-90390108:+LUSCCI.1040EER5.9033e-06-0.2509image
ENSG00000105793.14,GTPBP10LUSCJW.7.52.1EAG1.3343e-03-0.1733image
chr7:90389402-90390108:+MESOJW.7.52.1EER6.1906e-040.4811image
ENSG00000105793.14,GTPBP10MESOMG.132EAG3.6564e-030.3998image
ENSG00000105793.14,GTPBP10OVErlotinibEAG4.3682e-03-0.1730image
chr7:90389402-90390108:+OVCMKEER4.0280e-04-0.2158image
chr7:90389402-90390108:+PAADBortezomibEER1.3766e-02-0.2353image
chr7:90389402-90390108:+PCPGAZD.2281EER1.9598e-030.2788image
ENSG00000105793.14,GTPBP10PCPGAZD.2281EAG2.9481e-020.1918image
chr7:90389402-90390108:+PRADGW.441756EER3.2750e-040.1705image
ENSG00000105793.14,GTPBP10PRADAS601245EAG7.0293e-04-0.1595image
ENSG00000105793.14,GTPBP10READLapatinibEAG2.6634e-030.3114image
chr7:90389402-90390108:+READLapatinibEER1.0424e-030.3437image
chr7:90389402-90390108:+SARCAZ628EER1.8567e-030.2489image
ENSG00000105793.14,GTPBP10SARCLapatinibEAG7.2628e-040.2621image
chr7:90389402-90390108:+SKCMJNK.Inhibitor.VIIIEER2.1990e-02-0.1342image
ENSG00000105793.14,GTPBP10SKCMCGP.60474EAG1.1188e-02-0.1458image
chr7:90389402-90390108:+STADCI.1040EER2.7499e-02-0.1244image
ENSG00000105793.14,GTPBP10STADCHIR.99021EAG3.3529e-030.1582image
ENSG00000105793.14,GTPBP10TGCTBryostatin.1EAG4.9340e-040.3120image
chr7:90389402-90390108:+TGCTBryostatin.1EER4.2879e-070.4438image
ENSG00000105793.14,GTPBP10THCACI.1040EAG4.9442e-08-0.2482image
chr7:90389402-90390108:+THCACI.1040EER2.8308e-07-0.2346image
chr7:90389402-90390108:+THYMCEP.701EER1.0378e-050.4016image
ENSG00000105793.14,GTPBP10THYMAxitinibEAG1.4713e-030.2957image
chr7:90389402-90390108:+UCECLFM.A13EER2.4758e-02-0.2032image
ENSG00000105793.14,GTPBP10UCECBMS.708163EAG2.6846e-020.1949image
ENSG00000105793.14,GTPBP10UCSAUY922EAG2.0922e-03-0.4837image
chr7:90389402-90390108:+UCSBryostatin.1EER5.7713e-03-0.4571image
chr7:90389402-90390108:+UVMAUY922EER1.7804e-020.4793image
ENSG00000105793.14,GTPBP10UVMAP.24534EAG2.3905e-020.4503image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType