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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: YIPF4 (ImmuneEditome ID:84272)

1. Gene summary of enriched editing regions for YIPF4

check button Gene summary
Gene informationGene symbol

YIPF4

Gene ID

84272

GeneSynonymsFinGER4|Nbla11189
GeneCytomap

2p22.3

GeneTypeprotein-coding
GeneDescriptionprotein YIPF4|YIP1 family member 4|putative protein product of Nbla11189
GeneModificationdate20230329
UniprotIDQ9BSR8;H7C0D5
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr2:32281293-32282238:+ENST00000495355.1ENSG00000119820.9YIPF4ncRNA_intronicAluSz6,AluJb,FLAM_Achr2:32281293-32282238:+.alignment
chr2:32295624-32297404:+ENST00000238831.7ENSG00000119820.9YIPF4intronicAluSg7,AluSq2,L1MC4a,AluSp,MLT1D,Charlie15achr2:32295624-32297404:+.alignment
chr2:32295624-32297404:+ENST00000437765.1ENSG00000119820.9YIPF4intronicAluSg7,AluSq2,L1MC4a,AluSp,MLT1D,Charlie15achr2:32295624-32297404:+.alignment
chr2:32298699-32299060:+ENST00000238831.7ENSG00000119820.9YIPF4intronicAluSx1,AluSzchr2:32298699-32299060:+.alignment
chr2:32298699-32299060:+ENST00000437765.1ENSG00000119820.9YIPF4intronicAluSx1,AluSzchr2:32298699-32299060:+.alignment
chr2:32307584-32310882:+ENST00000238831.7ENSG00000119820.9YIPF4UTR3MER8,FLAM_C,AluJb,AluY,AluSp,AluSx1,Tigger4a,AluYcchr2:32307584-32310882:+.alignment
chr2:32312184-32315951:+ENST00000238831.7ENSG00000119820.9YIPF4UTR3FLAM_C,L1ME3B,AluSx1,AluSp,AluY,MLT1J,L2bchr2:32312184-32315951:+.alignment


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2. Tumor-specific enriched editing regions for YIPF4


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chr2:32307584-32310882:+BRCAEER5.3555e-31image
chr2:32312184-32315951:+BRCAEER2.0784e-06image
ENSG00000119820.9,YIPF4BRCAEAG5.1804e-31image
chr2:32307584-32310882:+COADEER1.5445e-15image
ENSG00000119820.9,YIPF4COADEAG1.0987e-15image
chr2:32307584-32310882:+HNSCEER3.1308e-11image
ENSG00000119820.9,YIPF4HNSCEAG3.1083e-11image
chr2:32307584-32310882:+KIRCEER1.4267e-02image
ENSG00000119820.9,YIPF4KIRCEAG1.5348e-02image
chr2:32307584-32310882:+KIRPEER7.8954e-07image
ENSG00000119820.9,YIPF4KIRPEAG5.7055e-06image
chr2:32307584-32310882:+LUADEER2.4035e-03image
ENSG00000119820.9,YIPF4LUADEAG2.0077e-03image
chr2:32307584-32310882:+LUSCEER4.5031e-14image
chr2:32312184-32315951:+LUSCEER8.1552e-03image
ENSG00000119820.9,YIPF4LUSCEAG2.2865e-14image
chr2:32307584-32310882:+PRADEER2.9879e-04image
chr2:32312184-32315951:+PRADEER2.6187e-02image
ENSG00000119820.9,YIPF4PRADEAG4.3853e-04image
chr2:32307584-32310882:+THCAEER1.7697e-04image
chr2:32312184-32315951:+THCAEER1.3296e-04image
ENSG00000119820.9,YIPF4THCAEAG6.1670e-05image
chr2:32307584-32310882:+UCECEER3.5448e-19image
ENSG00000119820.9,YIPF4UCECEAG4.0862e-17image


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
ENSG00000119820.9,YIPF4BRCAPathEAG3.1061e-023.8757e-020.0629image
chr2:32307584-32310882:+BRCAPathEER3.6243e-022.7799e-020.0671image
ENSG00000119820.9,YIPF4KIRPCliEAG2.9621e-035.1043e-040.2472image
chr2:32312184-32315951:+KIRPCliEER1.0847e-026.0127e-030.2859image
chr2:32307584-32310882:+KIRPCliEER2.3066e-026.5903e-030.1950image
chr2:32307584-32310882:+LUADPathEER2.2636e-021.5754e-020.1062image
ENSG00000119820.9,YIPF4LUADPathEAG2.7759e-021.8550e-020.1034image


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
chr2:32307584-32310882:+LGGEER3.6353e-022.5549e-021.7310e+03image
ENSG00000119820.9,YIPF4LGGEAG3.6353e-022.1292e-022.9829e+03image
chr2:32281293-32282238:+OVEER4.6448e-031.2240e-022.9407e+08image

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3. Enriched editing regions and immune related genes for YIPF4


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr2:32307584-32310882:+COADEERENSG00000267523,CTD-2537I9.12-0.22018.6032e-039.6262e-280.5952imageNELAVL1;NOP56;UPF1NADendritic_cells_activatedGSVA_HALLMARK_ADIPOGENESIS
chr2:32307584-32310882:+COADEERENSG00000207129,RNA5SP187-0.21279.9259e-031.5927e-150.4560imageNNNADendritic_cells_activatedGSVA_HALLMARK_UV_RESPONSE_UP
chr2:32307584-32310882:+COADEERENSG00000263050,RP11-667K14.30.21461.0827e-025.4437e-150.4482imageNHNRNPC;EIF4A3NANeutrophilsGSVA_HALLMARK_PEROXISOME
chr2:32307584-32310882:+COADEERENSG00000162545,CAMK2N1-0.20131.9803e-022.2048e-160.4681imageNELAVL1;HNRNPC;IGF2BP2;NOP56;RBFOX2;UPF1;CSTF2T;EIF4A3;U2AF2NADendritic_cells_activatedGSVA_HALLMARK_MYC_TARGETS_V2
chr2:32307584-32310882:+COADEERENSG00000144504,ANKMY1-0.17843.9498e-029.8664e-170.4729imageNELAVL1;HNRNPC;IGF2BP2;NOP56;NOP58;RBFOX2;UPF1;CSTF2T;EIF4A3;U2AF2NADendritic_cells_activatedGSVA_HALLMARK_XENOBIOTIC_METABOLISM
chr2:32307584-32310882:+UCECEERENSG00000277358,RP11-321C24.40.34322.6680e-036.7562e-130.5176imageNNNANeutrophilsGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING
chr2:32307584-32310882:+UCECEERENSG00000137767,SQRDL0.27442.3571e-023.9482e-100.4589imageNELAVL1;HNRNPC;IGF2BP2;NOP56;NOP58;RBFOX2;UPF1;CSTF2T;EIF4A3;U2AF2NAT_cells_CD8GSVA_HALLMARK_XENOBIOTIC_METABOLISM
chr2:32307584-32310882:+DLBCEERENSG00000270015,RP11-540B6.6-0.66521.3606e-028.0766e-04-0.5205imageNELAVL1;HNRNPC;IGF2BP2;NOP56;NOP58;RBFOX2;UPF1;CSTF2T;EIF4A3;U2AF2NAMast_cells_activatedGSVA_HALLMARK_PANCREAS_BETA_CELLS
chr2:32307584-32310882:+DLBCEERENSG00000005882,PDK2-0.67791.5887e-024.4759e-04-0.5414imageNELAVL1;HNRNPC;IGF2BP2;NOP56;NOP58;RBFOX2;UPF1;CSTF2T;EIF4A3;U2AF2NAB_cells_naiveGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING
chr2:32307584-32310882:+DLBCEERENSG00000147813,NAPRT0.68181.8171e-022.9683e-040.5552imageNELAVL1;IGF2BP2;NOP56;NOP58;RBFOX2;UPF1;CSTF2T;EIF4A3;U2AF2NAGSVA_HALLMARK_KRAS_SIGNALING_DN
chr2:32312184-32315951:+ESCAEERENSG00000121417,ZNF211-0.43722.0470e-042.9517e-07-0.4213imageNCNBP;CSTF2T;DDX54;EIF4A3;ELAVL1;FMR1;FXR1;GTF2F1;HNRNPC;HNRNPK;HNRNPL;IGF2BP2;KHSRP;MOV10;NOP56;NOP58;PRPF8;PTBP1;RBFOX2;RBM10;RNF219;SF3B4;SRSF1;TAF15;TIA1;U2AF1;U2AF2;UPF1;XRN2;ZNF184NADendritic_cells_activatedGSVA_HALLMARK_MTORC1_SIGNALING

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4. Enriched editing regions and immune related splicing for YIPF4


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr2:32307584-32310882:+
COADEERESENSG00000151092.12chr325719410:25719635:25720013:25720191:25729132:25729316-0.24311.2190e-021.4786e-12-0.4118imageNELAVL1;HNRNPC;IGF2BP2;NOP56;NOP58;RBFOX2;UPF1;CSTF2T;EIF4A3;U2AF2NAMast_cells_activatedGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING
ENSG00000119820.9,YIPF4
COADEAGESENSG00000152620.8chr536207169:36207265:36208624:36208690:36211843:362119220.24737.3673e-031.6248e-230.5565imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM22;RBM27;RBM47;RNF219;RTCB;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NADendritic_cells_activatedGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING
ENSG00000119820.9,YIPF4
COADEAGESENSG00000029363.11chr6136261300:136261477:136267028:136267175:136268161:136268273-0.24961.1750e-023.9136e-13-0.4193imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;RTCB;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZFP36;ZNF184BCLAF1Dendritic_cells_activatedGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSE
ENSG00000119820.9,YIPF4
COADEAGA3ENSG00000152620.8chr536211843:36211922:36207169:36207265:36207169:36208690-0.21893.6236e-021.0474e-17-0.4883imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM22;RBM27;RBM47;RNF219;RTCB;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NANK_cells_activatedGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSE
ENSG00000119820.9,YIPF4
COADEAGESENSG00000176731.7chr885214555:85214631:85214920:85215037:85217385:85217502-0.25618.4807e-031.6239e-21-0.5322imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;EIF4A3;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;FXR1;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MOV10;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YWHAG;ZNF184NANK_cells_restingGSVA_HALLMARK_BILE_ACID_METABOLISM
chr2:32307584-32310882:+
COADEERESENSG00000117143.9chr1162590326:162590511:162592731:162592782:162597791:162597858-0.23631.6516e-027.8527e-14-0.4312imageNELAVL1;HNRNPC;IGF2BP2;NOP56;NOP58;RBFOX2;UPF1;CSTF2T;EIF4A3;U2AF2NADendritic_cells_activatedGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING
chr2:32307584-32310882:+
COADEERESENSG00000147050.10chrX45061323:45061419:45062646:45062748:45063421:45063676-0.28961.3205e-051.2208e-09-0.4169imageNELAVL1;HNRNPC;IGF2BP2;NOP56;NOP58;RBFOX2;UPF1;CSTF2T;EIF4A3;U2AF2NAMast_cells_activatedGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING
chr2:32307584-32310882:+
COADEERESENSG00000029363.11chr6136261300:136261477:136267028:136267175:136268161:136268273-0.22662.9623e-023.6221e-12-0.4031imageNELAVL1;HNRNPC;IGF2BP2;NOP56;NOP58;RBFOX2;UPF1;CSTF2T;EIF4A3;U2AF2BCLAF1Dendritic_cells_activatedGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSE
ENSG00000119820.9,YIPF4
COADEAGESENSG00000147050.10chrX45061323:45061419:45062646:45062748:45063421:45063676-0.29161.7134e-051.0454e-09-0.4184imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CELF2;CNBP;CSTF2T;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR2;GTF2F1;HNRNPA1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHDRBS2;KHDRBS3;LARP7;LIN28;LIN28A;LIN28B;MBNL2;METTL3;MOV10;MSI2;NONO;NOP56;NOP58;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM47;RC3H1;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;ZC3H7B;ZNF184NAMast_cells_activatedGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING
chr2:32307584-32310882:+
COADEERESENSG00000152620.8chr536207169:36207265:36208624:36208690:36211843:362119220.26042.7662e-033.1005e-240.5639imageNELAVL1;HNRNPC;IGF2BP2;NOP56;NOP58;RBFOX2;UPF1;CSTF2T;EIF4A3;U2AF2NADendritic_cells_activatedGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING

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5. Enriched editing regions and immune infiltration for YIPF4


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chr2:32307584-32310882:+ACCEERDendritic_cells_resting4.1044e-020.2365image
ENSG00000119820.9,YIPF4ACCEAGDendritic_cells_resting4.2871e-020.2345image
chr2:32307584-32310882:+BLCAEERMacrophages_M12.1833e-090.2953image
chr2:32312184-32315951:+BLCAEERT_cells_CD4_memory_resting4.3715e-020.2155image
ENSG00000119820.9,YIPF4BLCAEAGMacrophages_M19.1023e-100.3008image
chr2:32307584-32310882:+BRCAEERB_cells_naive3.4127e-05-0.1258image
chr2:32312184-32315951:+BRCAEERB_cells_naive2.3958e-02-0.1270image
ENSG00000119820.9,YIPF4BRCAEAGB_cells_naive5.2281e-06-0.1380image
chr2:32307584-32310882:+CESCEERB_cells_naive3.2197e-03-0.1716image
ENSG00000119820.9,YIPF4CESCEAGB_cells_naive1.7867e-03-0.1811image
chr2:32307584-32310882:+CHOLEERNeutrophils3.7683e-020.3527image
ENSG00000119820.9,YIPF4CHOLEAGNeutrophils4.4942e-020.3411image
chr2:32307584-32310882:+COADEERDendritic_cells_activated9.6098e-040.1980image
chr2:32312184-32315951:+COADEERNeutrophils2.3956e-030.4781image
ENSG00000119820.9,YIPF4COADEAGDendritic_cells_activated3.4113e-040.2144image
chr2:32307584-32310882:+DLBCEERB_cells_naive1.8046e-02-0.3817image
ENSG00000119820.9,YIPF4DLBCEAGB_cells_naive2.2662e-02-0.3689image
chr2:32295624-32297404:+ESCAEERMacrophages_M03.5973e-020.2737image
chr2:32307584-32310882:+ESCAEERT_cells_regulatory_(Tregs)4.1457e-05-0.3181image
chr2:32312184-32315951:+ESCAEERMonocytes2.5237e-02-0.1912image
ENSG00000119820.9,YIPF4ESCAEAGT_cells_regulatory_(Tregs)5.7779e-05-0.3124image
chr2:32307584-32310882:+GBMEERMacrophages_M16.3326e-030.2111image
ENSG00000119820.9,YIPF4GBMEAGT_cells_CD4_memory_resting6.4159e-030.2108image
chr2:32307584-32310882:+HNSCEERT_cells_regulatory_(Tregs)1.7055e-05-0.1971image
ENSG00000119820.9,YIPF4HNSCEAGT_cells_regulatory_(Tregs)1.3176e-04-0.1753image
chr2:32307584-32310882:+KICHEERT_cells_regulatory_(Tregs)7.6543e-03-0.3330image
ENSG00000119820.9,YIPF4KICHEAGT_cells_regulatory_(Tregs)7.8361e-03-0.3321image
chr2:32307584-32310882:+KIRCEERT_cells_CD4_memory_activated1.4664e-060.2432image
chr2:32312184-32315951:+KIRCEERT_cells_CD4_memory_activated3.2542e-020.1432image
ENSG00000119820.9,YIPF4KIRCEAGT_cells_CD4_memory_activated3.5683e-060.2340image
chr2:32307584-32310882:+KIRPEERNK_cells_resting1.7283e-030.1871image
chr2:32312184-32315951:+KIRPEERMacrophages_M16.5639e-030.2373image
ENSG00000119820.9,YIPF4KIRPEAGNK_cells_resting1.1325e-040.2279image
chr2:32295624-32297404:+LAMLEERMacrophages_M21.6535e-02-0.3136image
chr2:32307584-32310882:+LAMLEERT_cells_CD4_naive1.0595e-02-0.2088image
ENSG00000119820.9,YIPF4LAMLEAGT_cells_CD4_naive4.2468e-03-0.2330image
chr2:32307584-32310882:+LGGEERT_cells_gamma_delta2.2482e-02-0.0993image
chr2:32312184-32315951:+LGGEERMacrophages_M22.3220e-020.1080image
ENSG00000119820.9,YIPF4LGGEAGT_cells_CD4_naive5.4273e-03-0.1209image
chr2:32312184-32315951:+LIHCEERDendritic_cells_activated9.9511e-040.3228image
chr2:32307584-32310882:+LUADEERT_cells_follicular_helper4.1657e-04-0.1548image
ENSG00000119820.9,YIPF4LUADEAGT_cells_follicular_helper3.9574e-04-0.1554image
chr2:32307584-32310882:+LUSCEERMast_cells_resting3.1608e-03-0.1324image
ENSG00000119820.9,YIPF4LUSCEAGMast_cells_resting3.6349e-03-0.1305image
chr2:32307584-32310882:+MESOEERDendritic_cells_activated8.1502e-030.2921image
ENSG00000119820.9,YIPF4MESOEAGDendritic_cells_activated9.2774e-030.2857image
chr2:32307584-32310882:+OVEERMacrophages_M12.9750e-030.1741image
chr2:32312184-32315951:+OVEERT_cells_regulatory_(Tregs)3.7506e-020.1388image
ENSG00000119820.9,YIPF4OVEAGMacrophages_M16.5923e-030.1595image
chr2:32307584-32310882:+PCPGEERMast_cells_resting4.5070e-03-0.2091image
chr2:32312184-32315951:+PCPGEERMast_cells_resting5.2310e-03-0.2340image
ENSG00000119820.9,YIPF4PCPGEAGMast_cells_resting8.4797e-03-0.1941image
chr2:32307584-32310882:+PRADEERB_cells_memory1.6326e-050.1922image
chr2:32312184-32315951:+PRADEERNK_cells_resting2.1389e-020.1544image
ENSG00000119820.9,YIPF4PRADEAGT_cells_regulatory_(Tregs)4.5780e-050.1816image
chr2:32307584-32310882:+READEERNK_cells_resting9.4411e-03-0.2650image
ENSG00000119820.9,YIPF4READEAGMacrophages_M13.8915e-020.2123image
chr2:32307584-32310882:+SARCEERDendritic_cells_activated4.9108e-030.1777image
chr2:32312184-32315951:+SARCEERMast_cells_resting4.2591e-02-0.2380image
ENSG00000119820.9,YIPF4SARCEAGT_cells_CD4_memory_activated2.2302e-030.1918image
chr2:32307584-32310882:+SKCMEERT_cells_CD4_memory_resting2.3256e-02-0.1074image
chr2:32312184-32315951:+SKCMEERNK_cells_activated7.5000e-030.2362image
ENSG00000119820.9,YIPF4SKCMEAGT_cells_CD4_memory_resting2.2137e-02-0.1082image
chr2:32295624-32297404:+STADEERMast_cells_activated1.6705e-030.2731image
chr2:32307584-32310882:+STADEERB_cells_naive3.9225e-05-0.2123image
chr2:32312184-32315951:+STADEERB_cells_memory1.3457e-02-0.1525image
ENSG00000119820.9,YIPF4STADEAGB_cells_naive3.2031e-05-0.2147image
chr2:32307584-32310882:+TGCTEERT_cells_CD4_memory_activated1.3804e-020.2007image
chr2:32312184-32315951:+TGCTEERPlasma_cells4.4886e-02-0.3688image
ENSG00000119820.9,YIPF4TGCTEAGT_cells_CD4_memory_activated1.0343e-020.2081image
chr2:32307584-32310882:+THCAEERDendritic_cells_activated5.7382e-040.1530image
ENSG00000119820.9,YIPF4THCAEAGDendritic_cells_activated1.7446e-030.1391image
chr2:32307584-32310882:+THYMEERT_cells_CD4_naive4.1182e-02-0.1968image
chr2:32312184-32315951:+THYMEERT_cells_gamma_delta1.7547e-030.4399image
ENSG00000119820.9,YIPF4THYMEAGT_cells_CD4_naive2.1214e-02-0.2166image
chr2:32307584-32310882:+UCECEERNeutrophils2.2053e-020.1766image
ENSG00000119820.9,YIPF4UCECEAGNeutrophils2.0321e-020.1778image
chr2:32307584-32310882:+UCSEERB_cells_naive6.1906e-03-0.3647image
ENSG00000119820.9,YIPF4UCSEAGB_cells_naive7.2051e-03-0.3585image
chr2:32307584-32310882:+UVMEERT_cells_CD4_memory_resting2.8913e-02-0.2799image
ENSG00000119820.9,YIPF4UVMEAGT_cells_CD4_memory_resting2.8572e-02-0.2805image


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6. Enriched editing regions and immune gene sets for YIPF4


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot
ENSG00000119820.9,YIPF4BRCAEAG1.9389e-090.18123.2263e-080.16718.2125e-050.11941.5464e-020.0736image
chr2:32307584-32310882:+BRCAEER1.2141e-070.16021.0668e-060.14792.6808e-030.09134.3356e-020.0615image
ENSG00000119820.9,YIPF4HNSCEAG1.1131e-050.20092.1181e-03-0.14131.1006e-040.17722.5583e-070.2348image
chr2:32307584-32310882:+HNSCEER4.0481e-060.21102.9126e-03-0.13726.6825e-050.18308.2509e-080.2445image
ENSG00000119820.9,YIPF4LUADEAG1.9535e-040.16339.4027e-040.14521.0522e-030.14383.8309e-050.1802image
chr2:32307584-32310882:+LUADEER1.5311e-040.16599.3771e-040.14529.7177e-040.14482.2980e-050.1852image
ENSG00000119820.9,YIPF4LUSCEAG1.0533e-060.21731.3992e-030.14322.3036e-040.16481.0202e-040.1738image
chr2:32307584-32310882:+LUSCEER1.5002e-060.21431.8373e-030.13972.7434e-040.16287.6537e-050.1768image
ENSG00000119820.9,YIPF4PAADEAG2.2356e-040.27332.0630e-030.22959.5935e-030.19371.8512e-040.2767image
chr2:32307584-32310882:+PAADEER2.0688e-040.27621.7341e-030.23458.5434e-030.19771.6496e-040.2803image
ENSG00000119820.9,YIPF4SARCEAG1.0206e-050.27404.6939e-030.17761.5170e-030.19881.2969e-040.2388image
chr2:32307584-32310882:+SARCEER3.3235e-070.31671.2346e-040.24091.7200e-040.23592.3989e-040.2308image
chr2:32312184-32315951:+STADEER7.6266e-050.24191.8096e-020.14594.2661e-030.17602.2682e-030.1878image
chr2:32307584-32310882:+STADEER5.2826e-170.41761.8444e-040.19352.0415e-120.35527.3513e-090.2953image
ENSG00000119820.9,YIPF4STADEAG4.2483e-180.43072.4029e-050.21801.4645e-120.35743.7683e-090.3007image


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
chr2:32307584-32310882:+ACCGSVA_HALLMARK_KRAS_SIGNALING_UPEER1.5780e-030.3587image
ENSG00000119820.9,YIPF4ACCGSVA_HALLMARK_INFLAMMATORY_RESPONSEEAG1.6504e-030.3573image
chr2:32307584-32310882:+BLCAGSVA_HALLMARK_HYPOXIAEER9.6928e-110.3181image
chr2:32312184-32315951:+BLCAGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEER2.0425e-030.3244image
ENSG00000119820.9,YIPF4BLCAGSVA_HALLMARK_HYPOXIAEAG4.8317e-110.3218image
chr2:32312184-32315951:+BRCAGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER2.2467e-060.2624image
chr2:32307584-32310882:+BRCAGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER3.0700e-190.2682image
ENSG00000119820.9,YIPF4BRCAGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG8.1271e-220.2860image
chr2:32307584-32310882:+CESCGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER1.4669e-060.2770image
ENSG00000119820.9,YIPF4CESCGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG2.0700e-070.2968image
chr2:32307584-32310882:+CHOLGSVA_HALLMARK_HEDGEHOG_SIGNALINGEER3.8885e-02-0.3507image
ENSG00000119820.9,YIPF4CHOLGSVA_HALLMARK_HEDGEHOG_SIGNALINGEAG4.6347e-02-0.3390image
chr2:32307584-32310882:+COADGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER7.3262e-04-0.2025image
ENSG00000119820.9,YIPF4COADGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG1.5683e-04-0.2260image
chr2:32312184-32315951:+COADGSVA_HALLMARK_BILE_ACID_METABOLISMEER4.9493e-02-0.3209image
ENSG00000119820.9,YIPF4DLBCGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG1.1405e-020.4061image
chr2:32307584-32310882:+DLBCGSVA_HALLMARK_MITOTIC_SPINDLEEER6.4986e-03-0.4339image
ENSG00000119820.9,YIPF4ESCAGSVA_HALLMARK_MTORC1_SIGNALINGEAG3.6235e-060.3568image
chr2:32312184-32315951:+ESCAGSVA_HALLMARK_MTORC1_SIGNALINGEER2.9753e-040.3045image
chr2:32307584-32310882:+ESCAGSVA_HALLMARK_MTORC1_SIGNALINGEER5.2487e-060.3513image
chr2:32307584-32310882:+GBMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.1766e-080.4247image
chr2:32312184-32315951:+GBMGSVA_HALLMARK_MTORC1_SIGNALINGEER4.7139e-030.2676image
ENSG00000119820.9,YIPF4GBMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG1.5793e-080.4213image
ENSG00000119820.9,YIPF4HNSCGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKBEAG6.8871e-090.2629image
chr2:32307584-32310882:+HNSCGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKBEER2.0732e-090.2722image
chr2:32307584-32310882:+KICHGSVA_HALLMARK_DNA_REPAIREER4.2104e-02-0.2569image
chr2:32307584-32310882:+KIRCGSVA_HALLMARK_SPERMATOGENESISEER2.3584e-070.2604image
chr2:32312184-32315951:+KIRCGSVA_HALLMARK_GLYCOLYSISEER1.0915e-050.2898image
ENSG00000119820.9,YIPF4KIRCGSVA_HALLMARK_SPERMATOGENESISEAG3.9893e-070.2552image
chr2:32307584-32310882:+KIRPGSVA_HALLMARK_MITOTIC_SPINDLEEER1.5639e-08-0.3310image
chr2:32312184-32315951:+KIRPGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEER1.6732e-020.2095image
ENSG00000119820.9,YIPF4KIRPGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG1.0817e-070.3099image
ENSG00000119820.9,YIPF4LAMLGSVA_HALLMARK_UNFOLDED_PROTEIN_RESPONSEEAG2.1402e-02-0.1884image
chr2:32312184-32315951:+LGGGSVA_HALLMARK_XENOBIOTIC_METABOLISMEER3.7136e-080.2581image
chr2:32307584-32310882:+LGGGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.5977e-080.2428image
ENSG00000119820.9,YIPF4LGGGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG4.9152e-120.2946image
chr2:32312184-32315951:+LIHCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER2.0276e-020.2307image
ENSG00000119820.9,YIPF4LIHCGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG1.9799e-120.3601image
chr2:32307584-32310882:+LIHCGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER1.2382e-120.3660image
chr2:32312184-32315951:+LUADGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER3.2449e-020.1954image
chr2:32307584-32310882:+LUADGSVA_HALLMARK_PROTEIN_SECRETIONEER4.2647e-070.2204image
ENSG00000119820.9,YIPF4LUADGSVA_HALLMARK_PROTEIN_SECRETIONEAG8.2303e-070.2150image
ENSG00000119820.9,YIPF4LUSCGSVA_HALLMARK_MTORC1_SIGNALINGEAG1.8700e-110.2958image
chr2:32307584-32310882:+LUSCGSVA_HALLMARK_MTORC1_SIGNALINGEER2.4426e-110.2942image
chr2:32312184-32315951:+LUSCGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEER2.9166e-020.2647image
chr2:32307584-32310882:+MESOGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKBEER5.2847e-050.4335image
ENSG00000119820.9,YIPF4MESOGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKBEAG1.1026e-040.4140image
chr2:32307584-32310882:+OVGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER5.7837e-190.4913image
chr2:32312184-32315951:+OVGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEER1.1903e-030.2148image
ENSG00000119820.9,YIPF4OVGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG5.5713e-190.4915image
ENSG00000119820.9,YIPF4PAADGSVA_HALLMARK_GLYCOLYSISEAG1.5970e-070.3806image
chr2:32307584-32310882:+PAADGSVA_HALLMARK_GLYCOLYSISEER1.5657e-070.3829image
chr2:32312184-32315951:+PCPGGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER1.4300e-02-0.2059image
chr2:32307584-32310882:+PCPGGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEER1.1851e-030.2379image
ENSG00000119820.9,YIPF4PCPGGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG4.9613e-03-0.2068image
chr2:32312184-32315951:+PRADGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER1.6021e-020.1615image
chr2:32307584-32310882:+PRADGSVA_HALLMARK_DNA_REPAIREER8.3814e-060.1986image
ENSG00000119820.9,YIPF4PRADGSVA_HALLMARK_DNA_REPAIREAG3.1392e-060.2071image
ENSG00000119820.9,YIPF4READGSVA_HALLMARK_ANDROGEN_RESPONSEEAG1.3526e-020.2526image
chr2:32307584-32310882:+READGSVA_HALLMARK_ANDROGEN_RESPONSEEER4.9600e-030.2860image
chr2:32307584-32310882:+SARCGSVA_HALLMARK_MTORC1_SIGNALINGEER1.1146e-070.3286image
ENSG00000119820.9,YIPF4SARCGSVA_HALLMARK_COMPLEMENTEAG3.9286e-070.3130image
ENSG00000119820.9,YIPF4SKCMGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG3.6553e-130.3347image
chr2:32307584-32310882:+SKCMGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER3.6910e-130.3350image
chr2:32295624-32297404:+STADGSVA_HALLMARK_TGF_BETA_SIGNALINGEER1.4752e-040.3268image
chr2:32281293-32282238:+STADGSVA_HALLMARK_PEROXISOMEEER1.2446e-040.4234image
chr2:32307584-32310882:+STADGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER7.8183e-190.4392image
ENSG00000119820.9,YIPF4STADGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG2.1550e-200.4565image
chr2:32312184-32315951:+STADGSVA_HALLMARK_P53_PATHWAYEER6.1013e-080.3269image
chr2:32312184-32315951:+TGCTGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKBEER1.1431e-030.5649image
chr2:32307584-32310882:+TGCTGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.2615e-020.2032image
ENSG00000119820.9,YIPF4TGCTGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG7.7668e-030.2159image
ENSG00000119820.9,YIPF4THCAGSVA_HALLMARK_GLYCOLYSISEAG7.1198e-090.2542image
chr2:32307584-32310882:+THCAGSVA_HALLMARK_GLYCOLYSISEER3.1066e-090.2603image
chr2:32312184-32315951:+THYMGSVA_HALLMARK_IL2_STAT5_SIGNALINGEER2.0875e-030.4334image
ENSG00000119820.9,YIPF4THYMGSVA_HALLMARK_KRAS_SIGNALING_DNEAG6.3568e-030.2553image
chr2:32307584-32310882:+THYMGSVA_HALLMARK_PROTEIN_SECRETIONEER2.1710e-03-0.2920image
chr2:32307584-32310882:+UCECGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER6.4640e-03-0.2093image
ENSG00000119820.9,YIPF4UCECGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG6.4489e-03-0.2082image
chr2:32312184-32315951:+UCECGSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALINGEER1.0336e-020.4469image
ENSG00000119820.9,YIPF4UCSGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG4.0253e-040.4606image
chr2:32307584-32310882:+UCSGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER1.2351e-040.4947image
ENSG00000119820.9,YIPF4UVMGSVA_HALLMARK_KRAS_SIGNALING_DNEAG1.0406e-060.5786image
chr2:32307584-32310882:+UVMGSVA_HALLMARK_KRAS_SIGNALING_DNEER9.6080e-070.5801image


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7. Enriched editing regions and drugs for YIPF4


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
chr2:32307584-32310882:+ACCBAY.61.3606EER1.2697e-020.2865image
ENSG00000119820.9,YIPF4ACCBAY.61.3606EAG1.0108e-020.2953image
chr2:32307584-32310882:+BLCACMKEER1.0630e-11-0.3333image
ENSG00000119820.9,YIPF4BLCACMKEAG4.5824e-11-0.3222image
chr2:32307584-32310882:+BRCAAS601245EER2.1328e-070.1571image
chr2:32312184-32315951:+BRCAAS601245EER1.6737e-030.1761image
ENSG00000119820.9,YIPF4BRCAAS601245EAG4.9145e-080.1649image
ENSG00000119820.9,YIPF4CESCCI.1040EAG8.2331e-07-0.2824image
chr2:32307584-32310882:+CESCCI.1040EER2.2627e-07-0.2968image
ENSG00000119820.9,YIPF4CHOLAP.24534EAG3.9854e-030.4744image
chr2:32307584-32310882:+CHOLAP.24534EER8.0288e-030.4409image
ENSG00000119820.9,YIPF4COADBI.D1870EAG3.5205e-04-0.2140image
chr2:32307584-32310882:+COADBI.D1870EER2.3211e-04-0.2203image
chr2:32312184-32315951:+COADGefitinibEER1.7126e-02-0.3846image
ENSG00000119820.9,YIPF4DLBCA.770041EAG8.4973e-05-0.5938image
chr2:32307584-32310882:+DLBCAZ628EER5.4806e-05-0.6062image
ENSG00000119820.9,YIPF4ESCABI.D1870EAG3.2044e-04-0.2809image
chr2:32307584-32310882:+ESCABI.D1870EER5.6864e-04-0.2695image
chr2:32312184-32315951:+ESCABI.D1870EER2.4362e-03-0.2570image
chr2:32295624-32297404:+ESCACyclopamineEER3.8718e-030.3705image
chr2:32307584-32310882:+GBMBIBW2992EER2.2404e-07-0.3889image
chr2:32312184-32315951:+GBMCMKEER6.3565e-03-0.2587image
ENSG00000119820.9,YIPF4GBMBIBW2992EAG2.4415e-07-0.3878image
ENSG00000119820.9,YIPF4HNSCAZD6244EAG9.3954e-14-0.3345image
chr2:32307584-32310882:+HNSCAZD6244EER4.7411e-12-0.3124image
ENSG00000119820.9,YIPF4KICHEHT.1864EAG2.7645e-020.2775image
chr2:32307584-32310882:+KICHEHT.1864EER3.5062e-020.2661image
chr2:32307584-32310882:+KIRCCHIR.99021EER7.0308e-060.2273image
chr2:32312184-32315951:+KIRCCCT007093EER3.8330e-050.2720image
ENSG00000119820.9,YIPF4KIRCCHIR.99021EAG1.5738e-060.2422image
chr2:32312184-32315951:+KIRPBIBW2992EER1.2091e-020.2195image
chr2:32307584-32310882:+KIRPBryostatin.1EER9.1272e-11-0.3760image
ENSG00000119820.9,YIPF4KIRPBryostatin.1EAG1.9278e-09-0.3478image
ENSG00000119820.9,YIPF4LAMLBleomycinEAG1.3725e-02-0.2015image
chr2:32307584-32310882:+LAMLBleomycinEER1.6162e-02-0.1968image
chr2:32295624-32297404:+LAMLAMG.706EER5.7267e-04-0.4386image
chr2:32307584-32310882:+LGGBexaroteneEER5.2197e-13-0.3073image
ENSG00000119820.9,YIPF4LGGBexaroteneEAG1.4531e-15-0.3379image
chr2:32312184-32315951:+LGGGNF.2EER1.3095e-05-0.2057image
chr2:32312184-32315951:+LIHCEHT.1864EER2.2575e-020.2268image
ENSG00000119820.9,YIPF4LIHCGSK.650394EAG3.9391e-070.2638image
chr2:32307584-32310882:+LIHCBAY.61.3606EER3.9938e-110.3421image
ENSG00000119820.9,YIPF4LUADBMS.708163EAG3.2748e-04-0.1575image
chr2:32312184-32315951:+LUADFTI.277EER4.7573e-03-0.2561image
chr2:32307584-32310882:+LUADBMS.708163EER4.0561e-04-0.1551image
ENSG00000119820.9,YIPF4LUSCCCT007093EAG1.7125e-090.2665image
chr2:32307584-32310882:+LUSCCCT007093EER2.4149e-090.2641image
chr2:32312184-32315951:+LUSCAKT.inhibitor.VIIIEER4.4456e-02-0.2445image
chr2:32307584-32310882:+MESODasatinibEER1.5175e-04-0.4087image
ENSG00000119820.9,YIPF4MESODasatinibEAG1.2673e-04-0.4107image
chr2:32312184-32315951:+OVEtoposideEER3.1917e-040.2378image
ENSG00000119820.9,YIPF4OVCCT007093EAG1.1750e-120.4021image
chr2:32307584-32310882:+OVCCT007093EER6.7985e-120.3893image
chr2:32307584-32310882:+PAADBIBW2992EER1.6698e-03-0.2353image
ENSG00000119820.9,YIPF4PAADBIBW2992EAG2.0079e-03-0.2300image
chr2:32312184-32315951:+PAADCyclopamineEER7.0434e-03-0.4247image
chr2:32312184-32315951:+PCPGEmbelinEER1.2187e-040.3180image
chr2:32307584-32310882:+PCPGBosutinibEER8.9213e-050.2855image
ENSG00000119820.9,YIPF4PCPGBosutinibEAG7.0264e-050.2895image
chr2:32312184-32315951:+PRADAxitinibEER1.5552e-020.1622image
ENSG00000119820.9,YIPF4PRADLFM.A13EAG1.9000e-060.2116image
chr2:32307584-32310882:+PRADLFM.A13EER4.0526e-060.2052image
ENSG00000119820.9,YIPF4READAMG.706EAG4.1075e-030.2934image
chr2:32307584-32310882:+READAMG.706EER2.5703e-030.3075image
chr2:32312184-32315951:+SARCBicalutamideEER1.2633e-02-0.2906image
chr2:32307584-32310882:+SARCBortezomibEER4.1615e-09-0.3616image
ENSG00000119820.9,YIPF4SARCBortezomibEAG1.6553e-11-0.4076image
ENSG00000119820.9,YIPF4SKCMGNF.2EAG1.3113e-08-0.2648image
chr2:32307584-32310882:+SKCMMG.132EER1.0226e-08-0.2679image
chr2:32312184-32315951:+SKCMAICAREER1.8151e-02-0.2094image
ENSG00000119820.9,YIPF4STADCCT007093EAG5.4780e-120.3487image
chr2:32281293-32282238:+STADMethotrexateEER2.2025e-02-0.2641image
chr2:32312184-32315951:+STADCCT007093EER3.7549e-050.2517image
chr2:32298699-32299060:+STADDasatinibEER1.3252e-020.4545image
chr2:32307584-32310882:+STADCCT007093EER1.2425e-100.3268image
chr2:32295624-32297404:+STADBexaroteneEER5.1221e-04-0.3005image
chr2:32307584-32310882:+TGCTJNJ.26854165EER6.0758e-03-0.2231image
chr2:32312184-32315951:+TGCTBortezomibEER9.7023e-03-0.4646image
ENSG00000119820.9,YIPF4TGCTJNJ.26854165EAG2.9732e-03-0.2402image
ENSG00000119820.9,YIPF4THCAAG.014699EAG8.6355e-060.1967image
chr2:32307584-32310882:+THCAAG.014699EER7.1497e-060.1987image
chr2:32312184-32315951:+THCACI.1040EER2.5604e-02-0.1238image
chr2:32312184-32315951:+THYMKIN001.135EER9.5391e-04-0.4618image
ENSG00000119820.9,YIPF4THYMCCT018159EAG3.5063e-04-0.3305image
chr2:32307584-32310882:+THYMEmbelinEER8.1716e-050.3698image
chr2:32312184-32315951:+UCECAUY922EER2.3903e-03-0.5180image
chr2:32307584-32310882:+UCECBIRB.0796EER7.7305e-060.3374image
ENSG00000119820.9,YIPF4UCECBIRB.0796EAG2.8716e-060.3501image
chr2:32307584-32310882:+UCSCCT007093EER1.0932e-040.4980image
ENSG00000119820.9,YIPF4UCSCCT007093EAG3.7242e-040.4629image
chr2:32307584-32310882:+UVMBexaroteneEER2.7137e-07-0.6030image
ENSG00000119820.9,YIPF4UVMBexaroteneEAG2.8714e-07-0.6020image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType