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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: SLC35F5 (ImmuneEditome ID:80255)

1. Gene summary of enriched editing regions for SLC35F5

check button Gene summary
Gene informationGene symbol

SLC35F5

Gene ID

80255

GeneSynonyms-
GeneCytomap

2q14.1

GeneTypeprotein-coding
GeneDescriptionsolute carrier family 35 member F5|HCV NS5A-transactivated protein 3|hepatitis C virus NS5A-transactivated protein 3
GeneModificationdate20230517
UniprotIDQ8WV83;B8ZZV6;B8ZZY4;A0A024RAD4
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr2:113707519-113708753:-ENST00000469702.4ENSG00000115084.11SLC35F5ncRNA_intronicAluSx3,AluSzchr2:113707519-113708753:-.alignment
chr2:113709801-113710797:-ENST00000469702.4ENSG00000115084.11SLC35F5ncRNA_intronicMER5A,AluJo,AluSzchr2:113709801-113710797:-.alignment
chr2:113712283-113712631:-ENST00000469702.4ENSG00000115084.11SLC35F5ncRNA_intronicAluYe5chr2:113712283-113712631:-.alignment
chr2:113740444-113741867:-ENST00000245680.5ENSG00000115084.11SLC35F5intronicL1MB3,AluSc,AluSpchr2:113740444-113741867:-.alignment
chr2:113740444-113741867:-ENST00000409106.4ENSG00000115084.11SLC35F5intronicL1MB3,AluSc,AluSpchr2:113740444-113741867:-.alignment
chr2:113753226-113754217:-ENST00000498768.1ENSG00000115084.11SLC35F5ncRNA_intronicL1MA9,AluSg,AluSq2chr2:113753226-113754217:-.alignment


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2. Tumor-specific enriched editing regions for SLC35F5


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chr2:113707519-113708753:-BRCAEER3.4179e-12image
chr2:113709801-113710797:-BRCAEER9.2735e-11image
ENSG00000115084.11,SLC35F5BRCAEAG1.9105e-09image
chr2:113707519-113708753:-COADEER1.1112e-07image
chr2:113709801-113710797:-COADEER3.3323e-04image
ENSG00000115084.11,SLC35F5COADEAG9.8082e-09image
chr2:113707519-113708753:-HNSCEER6.9327e-05image
chr2:113709801-113710797:-HNSCEER3.5738e-07image
ENSG00000115084.11,SLC35F5HNSCEAG4.1323e-08image
chr2:113707519-113708753:-KICHEER6.3366e-06image
chr2:113709801-113710797:-KICHEER2.1681e-07image
ENSG00000115084.11,SLC35F5KICHEAG4.3596e-08image
chr2:113707519-113708753:-KIRCEER3.8332e-03image
chr2:113709801-113710797:-KIRCEER7.4830e-13image
ENSG00000115084.11,SLC35F5KIRCEAG1.7126e-06image
chr2:113707519-113708753:-KIRPEER3.7647e-04image
ENSG00000115084.11,SLC35F5KIRPEAG7.7788e-03image
chr2:113707519-113708753:-LIHCEER5.6486e-04image
ENSG00000115084.11,SLC35F5LIHCEAG9.1621e-04image
chr2:113707519-113708753:-LUSCEER2.1437e-08image
chr2:113709801-113710797:-LUSCEER6.7004e-08image
ENSG00000115084.11,SLC35F5LUSCEAG1.2648e-10image
chr2:113707519-113708753:-THCAEER5.8477e-05image
chr2:113709801-113710797:-THCAEER1.4835e-12image
ENSG00000115084.11,SLC35F5THCAEAG4.9559e-10image


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
ENSG00000115084.11,SLC35F5KIRCPathEAG1.0183e-021.2453e-030.1399image
chr2:113709801-113710797:-KIRCPathEER7.6198e-045.2664e-040.1531image
chr2:113707519-113708753:-KIRPPathEER2.9913e-023.4403e-030.1818image
chr2:113707519-113708753:-LIHCPathEER2.7893e-025.7748e-03-0.1538image
ENSG00000115084.11,SLC35F5LIHCPathEAG9.9517e-031.0350e-03-0.1817image
chr2:113707519-113708753:-LUADPathEER3.9999e-022.0778e-020.1025image
ENSG00000115084.11,SLC35F5THCAPathEAG1.3798e-045.2705e-040.1546image
chr2:113709801-113710797:-THCAPathEER1.5599e-041.5285e-040.1751image
chr2:113709801-113710797:-UCECCliEER1.6474e-021.5128e-03-0.1836image


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
chr2:113709801-113710797:-CHOLEER2.0427e-022.8090e-022.2383e+04image
chr2:113712283-113712631:-KIRPEER4.0334e-031.7926e-022.2211e+05image
chr2:113709801-113710797:-STADEER3.5367e-032.6260e-023.2554e+01image

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3. Enriched editing regions and immune related genes for SLC35F5


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr2:113707519-113708753:-LUADEERENSG00000173209,AHSA2-0.41842.5678e-192.5911e-21-0.4035imageNNNAT_cells_CD4_memory_restingGSVA_HALLMARK_UV_RESPONSE_UP
chr2:113707519-113708753:-LUADEERENSG00000273271,AP000254.8-0.40751.8749e-189.5607e-22-0.4075imageNNNAEosinophilsGSVA_HALLMARK_MTORC1_SIGNALING
chr2:113707519-113708753:-LAMLEERENSG00000279841,RP11-274A11.40.39513.9633e-026.9925e-060.4104imageNNNAT_cells_CD4_memory_activatedGSVA_HALLMARK_DNA_REPAIR
chr2:113707519-113708753:-UCSEERENSG00000185418,TARSL2-0.57574.9523e-022.9174e-03-0.4011imageNNNAB_cells_naiveGSVA_HALLMARK_MYOGENESIS
chr2:113707519-113708753:-UCSEERENSG00000054116,TRAPPC30.61304.9523e-027.0876e-090.6963imageNNNAGSVA_HALLMARK_DNA_REPAIR
chr2:113707519-113708753:-THYMEERENSG00000104231,ZFAND1-0.32011.6753e-027.1166e-05-0.4020imageNNNANK_cells_activatedGSVA_HALLMARK_PROTEIN_SECRETION
chr2:113709801-113710797:-CESCEERENSG00000174775,HRAS0.28052.4757e-035.2506e-120.4442imageNNHRAST_cells_CD4_memory_restingGSVA_HALLMARK_PROTEIN_SECRETION
chr2:113709801-113710797:-CESCEERENSG00000034510,TMSB100.21902.6947e-023.9631e-130.4647imageNNNAB_cells_memoryGSVA_HALLMARK_MITOTIC_SPINDLE
chr2:113709801-113710797:-GBMEERENSG00000160613,PCSK7-0.52631.8386e-072.8290e-11-0.5123imageNNNAMacrophages_M0GSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr2:113709801-113710797:-GBMEERENSG00000157106,SMG1-0.51354.2326e-071.6048e-09-0.4705imageNNNAMacrophages_M2GSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr2:113709801-113710797:-GBMEERENSG00000102908,NFAT5-0.49879.9566e-071.6493e-09-0.4702imageNNNFAT5Macrophages_M2GSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr2:113709801-113710797:-GBMEERENSG00000198265,HELZ-0.49681.1921e-063.1928e-09-0.4627imageNNNAMonocytesGSVA_HALLMARK_MITOTIC_SPINDLE
chr2:113709801-113710797:-GBMEERENSG00000281896,RP11-274B21.13-0.49411.5150e-061.5906e-08-0.4439imageNNNAMonocytesGSVA_HALLMARK_FATTY_ACID_METABOLISM
chr2:113709801-113710797:-GBMEERENSG00000136731,UGGT1-0.49201.7203e-063.4740e-09-0.4618imageNNNAMacrophages_M0GSVA_HALLMARK_MITOTIC_SPINDLE
chr2:113709801-113710797:-GBMEERENSG00000055609,KMT2C-0.47913.7643e-061.4097e-07-0.4164imageNNNAMacrophages_M2GSVA_HALLMARK_MITOTIC_SPINDLE
chr2:113709801-113710797:-GBMEERENSG00000115760,BIRC6-0.47644.3670e-065.1011e-08-0.4295imageNNBIRC6MonocytesGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY

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4. Enriched editing regions and immune related splicing for SLC35F5


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr2:113709801-113710797:-
CESCEERA3ENSG00000182179.6chr349813061:49813168:49812647:49812734:49812647:498127380.13474.0171e-023.6102e-110.4411imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_PROTEIN_SECRETION
ENSG00000115084.11,SLC35F5
CESCEAGMEXENSG00000175215.5chr1257823652:57823727:57823903:57824005:57824028:57824089:57824226:57824319-0.23861.9514e-021.3709e-15-0.4461imageNADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM5;RC3H1;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;U2AF1;U2AF2;UPF1;WTAP;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAMacrophages_M2GSVA_HALLMARK_MITOTIC_SPINDLE
chr2:113707519-113708753:-
COADEERIRENSG00000131748.11chr1739657972:39658026:39658412:39658522-0.28846.9499e-056.9211e-10-0.4102imageNNNAMast_cells_activatedGSVA_HALLMARK_ANDROGEN_RESPONSE
chr2:113707519-113708753:-
GBMEERIRENSG00000155366.12chr1112705099:112705168:112705604:112705733-0.35285.8846e-041.6487e-07-0.4429imageNNNAMonocytesGSVA_HALLMARK_ADIPOGENESIS
ENSG00000115084.11,SLC35F5
GBMEAGIRENSG00000007392.12chr16227241:227336:229278:229374-0.41172.8327e-044.8968e-08-0.4125imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RC3H1;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;U2AF1;U2AF2;UPF1;XRN2;YWHAG;ZC3H7B;ZNF184NAT_cells_follicular_helperGSVA_HALLMARK_ESTROGEN_RESPONSE_LATE
chr2:113709801-113710797:-
GBMEERIRENSG00000205581.6chr2139345145:39347483:39348291:39348339-0.34278.8752e-031.9569e-07-0.4186imageNNNANK_cells_restingGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
ENSG00000115084.11,SLC35F5
GBMEAGIRENSG00000213398.3chr1667939749:67940478:67940736:67940825-0.33181.0092e-031.1367e-08-0.4922imageNACIN1;AUH;BCCIP;BUD13;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;EIF4A3;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FKBP4;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHSRP;LARP7;LIN28A;LIN28B;LSM11;MOV10;MSI1;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM22;RBM27;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZNF184NAMacrophages_M0GSVA_HALLMARK_PEROXISOME
chr2:113707519-113708753:-
GBMEERIRENSG00000132680.6chr1155913042:155914320:155915872:155915964-0.45684.1966e-056.1885e-08-0.4085imageNNNAGSVA_HALLMARK_ADIPOGENESIS
chr2:113707519-113708753:-
GBMEERIRENSG00000104863.7chr1949117854:49118018:49118351:49118460-0.41152.3353e-041.7001e-07-0.4052imageNNLIN7BT_cells_regulatory_(Tregs)GSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
ENSG00000115084.11,SLC35F5
GBMEAGIRENSG00000124357.8chr271072640:71073594:71075561:71075642-0.39832.8654e-041.0937e-07-0.4172imageNADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DKC1;EIF4A3;ELAVL1;EWSR1;FAM120A;FBL;FKBP4;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHSRP;LARP4B;LIN28;LIN28B;LSM11;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TRA2A;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;ZNF184NAMacrophages_M0GSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION

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5. Enriched editing regions and immune infiltration for SLC35F5


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chr2:113709801-113710797:-ACCEERPlasma_cells2.6102e-020.2921image
ENSG00000115084.11,SLC35F5ACCEAGDendritic_cells_activated3.9163e-02-0.2356image
chr2:113707519-113708753:-BLCAEERDendritic_cells_resting2.7144e-03-0.1572image
chr2:113709801-113710797:-BLCAEERT_cells_CD4_memory_activated1.4545e-020.1514image
ENSG00000115084.11,SLC35F5BLCAEAGT_cells_CD4_memory_resting6.0569e-04-0.1779image
chr2:113707519-113708753:-BRCAEERT_cells_CD4_memory_activated3.8574e-130.2203image
chr2:113709801-113710797:-BRCAEERNK_cells_activated5.9208e-070.1575image
chr2:113712283-113712631:-BRCAEERB_cells_naive3.4393e-02-0.0995image
ENSG00000115084.11,SLC35F5BRCAEAGT_cells_CD4_memory_activated4.2658e-120.2100image
chr2:113707519-113708753:-CESCEERMacrophages_M11.1609e-020.1496image
chr2:113709801-113710797:-CESCEERB_cells_naive3.0463e-03-0.1994image
ENSG00000115084.11,SLC35F5CESCEAGNK_cells_resting3.8366e-030.1693image
chr2:113707519-113708753:-CHOLEERT_cells_regulatory_(Tregs)3.9143e-040.5735image
chr2:113709801-113710797:-CHOLEERT_cells_CD81.9420e-040.6208image
ENSG00000115084.11,SLC35F5CHOLEAGMonocytes1.4817e-03-0.5168image
chr2:113707519-113708753:-COADEERMacrophages_M11.3189e-040.2306image
chr2:113709801-113710797:-COADEERNK_cells_activated1.5280e-020.1486image
ENSG00000115084.11,SLC35F5COADEAGMacrophages_M12.0550e-020.1401image
chr2:113707519-113708753:-DLBCEERMacrophages_M12.6987e-020.4105image
chr2:113707519-113708753:-ESCAEERB_cells_naive3.9951e-04-0.2766image
chr2:113709801-113710797:-ESCAEERT_cells_CD81.1372e-040.3004image
chr2:113740444-113741867:-ESCAEERNK_cells_activated2.1561e-020.3093image
ENSG00000115084.11,SLC35F5ESCAEAGMacrophages_M27.8939e-050.3060image
chr2:113707519-113708753:-GBMEERNeutrophils2.1614e-02-0.1798image
chr2:113709801-113710797:-GBMEERMacrophages_M23.6091e-030.2378image
ENSG00000115084.11,SLC35F5GBMEAGT_cells_regulatory_(Tregs)5.5518e-03-0.2156image
chr2:113707519-113708753:-HNSCEERT_cells_CD4_memory_activated3.1988e-020.1013image
chr2:113709801-113710797:-HNSCEERB_cells_naive1.1485e-03-0.1604image
ENSG00000115084.11,SLC35F5HNSCEAGMast_cells_activated7.2936e-030.1251image
chr2:113707519-113708753:-KICHEERT_cells_CD82.0011e-04-0.4487image
ENSG00000115084.11,SLC35F5KICHEAGB_cells_naive1.1295e-02-0.3124image
chr2:113707519-113708753:-KIRCEERT_cells_CD4_memory_resting2.3116e-04-0.1873image
chr2:113709801-113710797:-KIRCEERT_cells_regulatory_(Tregs)6.8019e-050.2053image
chr2:113712283-113712631:-KIRCEERT_cells_CD4_memory_activated2.9718e-030.1963image
ENSG00000115084.11,SLC35F5KIRCEAGT_cells_gamma_delta8.2106e-040.1703image
chr2:113707519-113708753:-KIRPEERT_cells_CD4_memory_resting9.2643e-05-0.2295image
chr2:113709801-113710797:-KIRPEERT_cells_CD82.1916e-030.1895image
ENSG00000115084.11,SLC35F5KIRPEAGT_cells_CD4_memory_resting9.7824e-05-0.2287image
chr2:113740444-113741867:-LAMLEEREosinophils1.5376e-020.4792image
chr2:113707519-113708753:-LGGEERDendritic_cells_resting2.8262e-020.0969image
chr2:113709801-113710797:-LGGEERNK_cells_activated2.3181e-020.1033image
ENSG00000115084.11,SLC35F5LGGEAGNK_cells_activated2.6512e-020.0972image
chr2:113707519-113708753:-LIHCEERMacrophages_M01.2784e-03-0.1732image
chr2:113709801-113710797:-LIHCEERPlasma_cells1.3093e-020.1561image
ENSG00000115084.11,SLC35F5LIHCEAGMacrophages_M01.2561e-03-0.1730image
chr2:113707519-113708753:-LUADEERB_cells_naive3.9337e-05-0.1813image
chr2:113709801-113710797:-LUADEERT_cells_CD4_memory_resting7.9675e-03-0.1193image
ENSG00000115084.11,SLC35F5LUADEAGT_cells_CD4_memory_activated5.0718e-050.1778image
chr2:113707519-113708753:-LUSCEERMast_cells_resting3.7391e-03-0.1325image
chr2:113709801-113710797:-LUSCEERMacrophages_M21.3636e-03-0.1509image
ENSG00000115084.11,SLC35F5LUSCEAGMast_cells_resting9.1086e-03-0.1188image
chr2:113709801-113710797:-MESOEERMacrophages_M01.3426e-040.4378image
ENSG00000115084.11,SLC35F5MESOEAGMonocytes3.8303e-02-0.2306image
chr2:113707519-113708753:-OVEERNeutrophils7.5207e-030.1586image
chr2:113709801-113710797:-OVEERT_cells_CD4_memory_activated5.5520e-040.2274image
chr2:113712283-113712631:-OVEERB_cells_memory5.7281e-03-0.2529image
ENSG00000115084.11,SLC35F5OVEAGNeutrophils9.0337e-030.1547image
chr2:113709801-113710797:-PAADEERT_cells_CD4_memory_resting6.7343e-03-0.2102image
chr2:113709801-113710797:-PCPGEERNK_cells_resting9.9474e-050.3134image
chr2:113707519-113708753:-PRADEERDendritic_cells_activated5.5773e-030.1250image
chr2:113709801-113710797:-PRADEERDendritic_cells_resting4.8290e-04-0.1653image
ENSG00000115084.11,SLC35F5PRADEAGT_cells_regulatory_(Tregs)1.4669e-040.1700image
chr2:113707519-113708753:-READEERMast_cells_activated5.6814e-030.2832image
chr2:113709801-113710797:-READEERT_cells_CD4_naive1.7105e-030.3226image
chr2:113709801-113710797:-SARCEERT_cells_CD4_memory_activated2.5227e-040.2599image
chr2:113707519-113708753:-SKCMEERPlasma_cells4.4618e-030.1372image
chr2:113709801-113710797:-SKCMEERNK_cells_activated3.4863e-050.2077image
ENSG00000115084.11,SLC35F5SKCMEAGT_cells_CD4_memory_resting6.4282e-04-0.1624image
chr2:113709801-113710797:-STADEERMacrophages_M25.2803e-030.1475image
chr2:113712283-113712631:-STADEERNeutrophils6.0710e-030.1619image
chr2:113740444-113741867:-STADEERNK_cells_activated1.9246e-020.2361image
chr2:113753226-113754217:-STADEERDendritic_cells_activated1.8206e-020.3396image
ENSG00000115084.11,SLC35F5STADEAGT_cells_CD4_memory_activated8.8337e-040.1736image
chr2:113707519-113708753:-TGCTEERMacrophages_M21.9923e-03-0.3086image
chr2:113709801-113710797:-TGCTEERPlasma_cells5.2160e-050.4196image
ENSG00000115084.11,SLC35F5TGCTEAGB_cells_naive2.0085e-050.3961image
chr2:113707519-113708753:-THCAEERMacrophages_M29.8063e-030.1156image
chr2:113709801-113710797:-THCAEERDendritic_cells_resting2.4763e-020.1042image
ENSG00000115084.11,SLC35F5THCAEAGDendritic_cells_activated3.8428e-030.1291image
chr2:113709801-113710797:-THYMEERT_cells_regulatory_(Tregs)3.9829e-040.4426image
chr2:113707519-113708753:-UCECEERT_cells_CD4_naive3.7322e-020.1696image
chr2:113709801-113710797:-UCECEERT_cells_follicular_helper1.6411e-030.3036image
chr2:113707519-113708753:-UCSEERB_cells_naive1.8913e-02-0.3215image
ENSG00000115084.11,SLC35F5UCSEAGB_cells_naive3.5346e-02-0.2897image
chr2:113707519-113708753:-UVMEERT_cells_CD4_naive2.3859e-020.3100image
chr2:113709801-113710797:-UVMEERDendritic_cells_resting6.5198e-040.5221image
ENSG00000115084.11,SLC35F5UVMEAGT_cells_follicular_helper2.1206e-02-0.3130image


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6. Enriched editing regions and immune gene sets for SLC35F5


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot
chr2:113707519-113708753:-KIRPEER3.1174e-02image1.8950e-020.1389image
ENSG00000115084.11,SLC35F5KIRPEAG3.8531e-03image4.0809e-020.1212image
chr2:113707519-113708753:-LUSCEER2.3299e-02image5.1281e-030.1280image


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot
chr2:113707519-113708753:-BRCAEER2.7694e-130.22162.1064e-080.17093.7777e-050.12611.0337e-020.0787image
chr2:113712283-113712631:-BRCAEER3.9275e-070.23593.1494e-030.13868.0277e-040.15711.5368e-020.1139image
ENSG00000115084.11,SLC35F5BRCAEAG2.3238e-140.23073.5189e-070.15523.7872e-060.14104.3450e-040.1075image
chr2:113707519-113708753:-LUADEER1.5951e-080.24747.0515e-050.17542.2784e-050.18677.6941e-150.3356image
ENSG00000115084.11,SLC35F5LUADEAG4.3357e-090.25537.8208e-050.17331.1035e-050.19255.6481e-160.3468image


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
chr2:113709801-113710797:-ACCGSVA_HALLMARK_TGF_BETA_SIGNALINGEER1.1214e-02-0.3308image
ENSG00000115084.11,SLC35F5ACCGSVA_HALLMARK_PEROXISOMEEAG9.0963e-03-0.2954image
chr2:113707519-113708753:-ACCGSVA_HALLMARK_PEROXISOMEEER4.9416e-03-0.3172image
chr2:113709801-113710797:-BLCAGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER5.2332e-050.2481image
ENSG00000115084.11,SLC35F5BLCAGSVA_HALLMARK_KRAS_SIGNALING_DNEAG2.4964e-040.1898image
chr2:113707519-113708753:-BLCAGSVA_HALLMARK_KRAS_SIGNALING_DNEER1.5965e-030.1653image
chr2:113709801-113710797:-BRCAGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER7.6798e-210.2908image
ENSG00000115084.11,SLC35F5BRCAGSVA_HALLMARK_UV_RESPONSE_UPEAG4.9044e-240.3026image
chr2:113707519-113708753:-BRCAGSVA_HALLMARK_MTORC1_SIGNALINGEER3.7341e-190.2697image
chr2:113712283-113712631:-BRCAGSVA_HALLMARK_MYC_TARGETS_V1EER1.2292e-070.2456image
chr2:113709801-113710797:-CESCGSVA_HALLMARK_PROTEIN_SECRETIONEER8.6735e-05-0.2621image
ENSG00000115084.11,SLC35F5CESCGSVA_HALLMARK_P53_PATHWAYEAG1.2617e-040.2232image
chr2:113707519-113708753:-CESCGSVA_HALLMARK_IL6_JAK_STAT3_SIGNALINGEER8.2100e-050.2315image
chr2:113709801-113710797:-CHOLGSVA_HALLMARK_DNA_REPAIREER1.5342e-020.4316image
ENSG00000115084.11,SLC35F5CHOLGSVA_HALLMARK_BILE_ACID_METABOLISMEAG2.9254e-02-0.3688image
chr2:113707519-113708753:-CHOLGSVA_HALLMARK_BILE_ACID_METABOLISMEER9.3504e-03-0.4392image
chr2:113707519-113708753:-COADGSVA_HALLMARK_ALLOGRAFT_REJECTIONEER1.1363e-070.3159image
chr2:113709801-113710797:-COADGSVA_HALLMARK_DNA_REPAIREER6.7356e-030.1658image
ENSG00000115084.11,SLC35F5COADGSVA_HALLMARK_ALLOGRAFT_REJECTIONEAG2.2213e-040.2217image
chr2:113707519-113708753:-DLBCGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER3.9586e-030.5185image
chr2:113707519-113708753:-ESCAGSVA_HALLMARK_HYPOXIAEER2.7605e-030.2352image
chr2:113709801-113710797:-ESCAGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.2492e-030.2530image
ENSG00000115084.11,SLC35F5ESCAGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG3.8721e-050.3183image
chr2:113709801-113710797:-GBMGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEER1.6887e-080.4432image
ENSG00000115084.11,SLC35F5GBMGSVA_HALLMARK_FATTY_ACID_METABOLISMEAG1.2746e-070.3983image
chr2:113707519-113708753:-GBMGSVA_HALLMARK_FATTY_ACID_METABOLISMEER5.7356e-070.3798image
chr2:113709801-113710797:-HNSCGSVA_HALLMARK_DNA_REPAIREER6.9758e-080.2630image
ENSG00000115084.11,SLC35F5HNSCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG3.0122e-050.1934image
chr2:113707519-113708753:-HNSCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER4.9758e-030.1325image
chr2:113709801-113710797:-KICHGSVA_HALLMARK_MITOTIC_SPINDLEEER2.4713e-05-0.5318image
ENSG00000115084.11,SLC35F5KIRCGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG4.7970e-110.3278image
chr2:113712283-113712631:-KIRCGSVA_HALLMARK_MITOTIC_SPINDLEEER2.4837e-04-0.2409image
chr2:113707519-113708753:-KIRCGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER2.6753e-100.3159image
chr2:113709801-113710797:-KIRCGSVA_HALLMARK_MITOTIC_SPINDLEEER5.8939e-09-0.2963image
chr2:113709801-113710797:-KIRPGSVA_HALLMARK_MITOTIC_SPINDLEEER2.4974e-13-0.4341image
ENSG00000115084.11,SLC35F5KIRPGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG9.0243e-090.3322image
chr2:113707519-113708753:-KIRPGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER4.6766e-070.2932image
chr2:113712283-113712631:-KIRPGSVA_HALLMARK_XENOBIOTIC_METABOLISMEER8.1998e-050.3634image
chr2:113707519-113708753:-LAMLGSVA_HALLMARK_UV_RESPONSE_DNEER1.7997e-020.2232image
ENSG00000115084.11,SLC35F5LAMLGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG3.6402e-02-0.1722image
chr2:113740444-113741867:-LAMLGSVA_HALLMARK_DNA_REPAIREER1.0870e-030.6143image
chr2:113709801-113710797:-LGGGSVA_HALLMARK_MITOTIC_SPINDLEEER6.7569e-10-0.2761image
ENSG00000115084.11,SLC35F5LGGGSVA_HALLMARK_KRAS_SIGNALING_DNEAG1.2509e-110.2910image
chr2:113707519-113708753:-LGGGSVA_HALLMARK_MYOGENESISEER9.8179e-070.2141image
chr2:113707519-113708753:-LIHCGSVA_HALLMARK_XENOBIOTIC_METABOLISMEER4.7843e-130.3773image
chr2:113709801-113710797:-LIHCGSVA_HALLMARK_TGF_BETA_SIGNALINGEER3.7447e-05-0.2566image
ENSG00000115084.11,SLC35F5LIHCGSVA_HALLMARK_XENOBIOTIC_METABOLISMEAG2.6110e-140.3947image
chr2:113709801-113710797:-LUADGSVA_HALLMARK_HYPOXIAEER7.7030e-070.2202image
ENSG00000115084.11,SLC35F5LUADGSVA_HALLMARK_HYPOXIAEAG5.6481e-160.3468image
chr2:113707519-113708753:-LUADGSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALINGEER6.2743e-200.3903image
chr2:113709801-113710797:-LUSCGSVA_HALLMARK_XENOBIOTIC_METABOLISMEER3.8255e-05-0.1933image
ENSG00000115084.11,SLC35F5LUSCGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKBEAG2.6858e-030.1366image
chr2:113707519-113708753:-LUSCGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKBEER1.1900e-040.1753image
chr2:113707519-113708753:-MESOGSVA_HALLMARK_IL2_STAT5_SIGNALINGEER7.9738e-030.2929image
chr2:113709801-113710797:-MESOGSVA_HALLMARK_MITOTIC_SPINDLEEER1.1792e-03-0.3773image
ENSG00000115084.11,SLC35F5MESOGSVA_HALLMARK_COAGULATIONEAG1.3636e-020.2731image
chr2:113709801-113710797:-OVGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEER6.8617e-060.2936image
ENSG00000115084.11,SLC35F5OVGSVA_HALLMARK_DNA_REPAIREAG2.2260e-070.3015image
chr2:113712283-113712631:-OVGSVA_HALLMARK_SPERMATOGENESISEER2.5705e-02-0.2053image
chr2:113707519-113708753:-OVGSVA_HALLMARK_MYC_TARGETS_V1EER3.7956e-070.2964image
chr2:113709801-113710797:-PAADGSVA_HALLMARK_PROTEIN_SECRETIONEER4.4271e-05-0.3123image
ENSG00000115084.11,SLC35F5PAADGSVA_HALLMARK_MYOGENESISEAG2.5327e-030.2269image
chr2:113707519-113708753:-PAADGSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITIONEER5.4100e-030.2094image
chr2:113709801-113710797:-PCPGGSVA_HALLMARK_ANDROGEN_RESPONSEEER3.1506e-04-0.2912image
ENSG00000115084.11,SLC35F5PCPGGSVA_HALLMARK_MYC_TARGETS_V2EAG9.1740e-03-0.1959image
chr2:113707519-113708753:-PCPGGSVA_HALLMARK_MYC_TARGETS_V2EER3.1338e-02-0.1628image
chr2:113709801-113710797:-PRADGSVA_HALLMARK_MITOTIC_SPINDLEEER2.3315e-14-0.3523image
ENSG00000115084.11,SLC35F5PRADGSVA_HALLMARK_PROTEIN_SECRETIONEAG2.1879e-06-0.2112image
chr2:113707519-113708753:-PRADGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER9.1830e-05-0.1758image
chr2:113707519-113708753:-READGSVA_HALLMARK_ALLOGRAFT_REJECTIONEER1.4490e-030.3239image
chr2:113709801-113710797:-READGSVA_HALLMARK_UV_RESPONSE_DNEER3.1398e-03-0.3047image
ENSG00000115084.11,SLC35F5READGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG9.8962e-040.3326image
chr2:113709801-113710797:-SARCGSVA_HALLMARK_P53_PATHWAYEER2.4191e-080.3873image
ENSG00000115084.11,SLC35F5SARCGSVA_HALLMARK_APICAL_SURFACEEAG9.0359e-040.2151image
chr2:113707519-113708753:-SARCGSVA_HALLMARK_UNFOLDED_PROTEIN_RESPONSEEER2.5571e-020.1463image
chr2:113709801-113710797:-SKCMGSVA_HALLMARK_ANDROGEN_RESPONSEEER2.4065e-05-0.2118image
ENSG00000115084.11,SLC35F5SKCMGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG4.5195e-050.1936image
chr2:113707519-113708753:-SKCMGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER1.9115e-030.1496image
chr2:113709801-113710797:-STADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER7.8353e-060.2344image
chr2:113753226-113754217:-STADGSVA_HALLMARK_GLYCOLYSISEER1.3846e-020.3530image
ENSG00000115084.11,SLC35F5STADGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG5.2890e-080.2804image
chr2:113740444-113741867:-STADGSVA_HALLMARK_KRAS_SIGNALING_DNEER7.4264e-030.2689image
chr2:113712283-113712631:-STADGSVA_HALLMARK_MYC_TARGETS_V1EER5.7091e-030.1631image
chr2:113707519-113708753:-STADGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER9.7717e-050.2100image
chr2:113709801-113710797:-TGCTGSVA_HALLMARK_NOTCH_SIGNALINGEER1.5619e-04-0.3945image
ENSG00000115084.11,SLC35F5TGCTGSVA_HALLMARK_SPERMATOGENESISEAG3.2361e-050.3869image
chr2:113707519-113708753:-TGCTGSVA_HALLMARK_SPERMATOGENESISEER2.0940e-040.3661image
chr2:113707519-113708753:-THCAGSVA_HALLMARK_GLYCOLYSISEER1.3720e-030.1430image
chr2:113709801-113710797:-THCAGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER3.7683e-130.3287image
ENSG00000115084.11,SLC35F5THCAGSVA_HALLMARK_GLYCOLYSISEAG6.2305e-120.3010image
chr2:113707519-113708753:-THYMGSVA_HALLMARK_MYC_TARGETS_V2EER1.9655e-020.2429image
chr2:113709801-113710797:-THYMGSVA_HALLMARK_ALLOGRAFT_REJECTIONEER1.2001e-030.4083image
ENSG00000115084.11,SLC35F5THYMGSVA_HALLMARK_MTORC1_SIGNALINGEAG1.4181e-020.2509image
chr2:113707519-113708753:-UCECGSVA_HALLMARK_PEROXISOMEEER4.8402e-030.2282image
chr2:113709801-113710797:-UCECGSVA_HALLMARK_PANCREAS_BETA_CELLSEER1.0007e-030.3166image
ENSG00000115084.11,SLC35F5UCECGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEAG2.1916e-030.2383image
chr2:113709801-113710797:-UCSGSVA_HALLMARK_DNA_REPAIREER7.4518e-030.4446image
ENSG00000115084.11,SLC35F5UCSGSVA_HALLMARK_DNA_REPAIREAG6.6765e-030.3682image
chr2:113707519-113708753:-UCSGSVA_HALLMARK_DNA_REPAIREER3.3157e-030.3962image
chr2:113707519-113708753:-UVMGSVA_HALLMARK_DNA_REPAIREER1.5134e-020.3321image
ENSG00000115084.11,SLC35F5UVMGSVA_HALLMARK_KRAS_SIGNALING_DNEAG2.8516e-020.2982image


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7. Enriched editing regions and drugs for SLC35F5


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
chr2:113709801-113710797:-ACCJNK.Inhibitor.VIIIEER2.0649e-03-0.3964image
ENSG00000115084.11,SLC35F5ACCJNK.Inhibitor.VIIIEAG2.2920e-03-0.3426image
chr2:113707519-113708753:-ACCJNK.Inhibitor.VIIIEER7.5222e-03-0.3024image
chr2:113709801-113710797:-BLCABMS.509744EER3.0564e-03-0.1830image
ENSG00000115084.11,SLC35F5BLCACGP.60474EAG6.8207e-04-0.1763image
chr2:113707519-113708753:-BLCACGP.082996EER1.7727e-03-0.1637image
chr2:113709801-113710797:-BRCAA.770041EER2.5083e-11-0.2097image
ENSG00000115084.11,SLC35F5BRCACCT007093EAG2.5319e-110.2024image
chr2:113707519-113708753:-BRCACCT007093EER1.2419e-080.1736image
chr2:113712283-113712631:-BRCACCT007093EER3.2825e-040.1682image
chr2:113709801-113710797:-CESCGW843682XEER3.2488e-05-0.2769image
ENSG00000115084.11,SLC35F5CESCCGP.082996EAG1.5412e-06-0.2778image
chr2:113707519-113708753:-CESCJNK.Inhibitor.VIIIEER1.7702e-06-0.2791image
chr2:113709801-113710797:-CHOLBortezomibEER2.1305e-03-0.5307image
ENSG00000115084.11,SLC35F5CHOLBAY.61.3606EAG2.1480e-02-0.3874image
chr2:113707519-113708753:-CHOLBleomycinEER2.3892e-02-0.3867image
chr2:113707519-113708753:-COADKU.55933EER4.1220e-08-0.3262image
chr2:113709801-113710797:-COADKU.55933EER4.4482e-04-0.2138image
ENSG00000115084.11,SLC35F5COADKU.55933EAG1.2572e-05-0.2609image
chr2:113707519-113708753:-DLBCJNK.9LEER4.2584e-03-0.5149image
ENSG00000115084.11,SLC35F5DLBCATRAEAG1.0580e-02-0.4674image
chr2:113707519-113708753:-ESCACGP.60474EER2.3597e-04-0.2868image
chr2:113709801-113710797:-ESCACGP.60474EER2.1808e-05-0.3288image
ENSG00000115084.11,SLC35F5ESCACGP.60474EAG2.0425e-06-0.3642image
chr2:113709801-113710797:-GBMAZD6482EER1.4285e-070.4162image
ENSG00000115084.11,SLC35F5GBMAZD6482EAG9.1707e-070.3723image
chr2:113707519-113708753:-GBMFTI.277EER1.0460e-030.2545image
chr2:113709801-113710797:-HNSCDocetaxelEER2.3544e-08-0.2720image
ENSG00000115084.11,SLC35F5HNSCCI.1040EAG6.5298e-06-0.2087image
chr2:113707519-113708753:-HNSCBosutinibEER4.9911e-04-0.1640image
chr2:113709801-113710797:-KICHBryostatin.1EER3.7900e-05-0.5213image
ENSG00000115084.11,SLC35F5KICHLFM.A13EAG1.6235e-02-0.2971image
ENSG00000115084.11,SLC35F5KIRCBMS.536924EAG7.9866e-10-0.3085image
chr2:113712283-113712631:-KIRCBIBW2992EER2.2944e-050.2776image
chr2:113707519-113708753:-KIRCCI.1040EER1.0376e-08-0.2876image
chr2:113709801-113710797:-KIRCBMS.536924EER4.2039e-08-0.2806image
chr2:113709801-113710797:-KIRPAZD6482EER9.2152e-100.3687image
ENSG00000115084.11,SLC35F5KIRPBAY.61.3606EAG5.5661e-120.3933image
chr2:113707519-113708753:-KIRPGefitinibEER1.3922e-080.3282image
chr2:113712283-113712631:-KIRPBosutinibEER1.6346e-050.3950image
chr2:113707519-113708753:-LAMLBicalutamideEER4.9451e-02-0.1861image
ENSG00000115084.11,SLC35F5LAMLErlotinibEAG1.6154e-02-0.1975image
chr2:113740444-113741867:-LAMLCCT007093EER1.0659e-030.6151image
chr2:113709801-113710797:-LGGAP.24534EER1.8940e-060.2148image
ENSG00000115084.11,SLC35F5LGGGemcitabineEAG1.6057e-100.2754image
chr2:113707519-113708753:-LGGBMS.708163EER4.2869e-06-0.2014image
chr2:113707519-113708753:-LIHCBMS.754807EER5.2418e-130.3777image
chr2:113709801-113710797:-LIHCBMS.536924EER7.3586e-05-0.2471image
ENSG00000115084.11,SLC35F5LIHCBMS.754807EAG3.0374e-130.3803image
chr2:113709801-113710797:-LUADCGP.60474EER1.1772e-06-0.2166image
ENSG00000115084.11,SLC35F5LUADGemcitabineEAG1.8938e-10-0.2762image
chr2:113707519-113708753:-LUADBMS.509744EER1.2465e-11-0.2946image
chr2:113709801-113710797:-LUSCGDC.0449EER3.0818e-04-0.1697image
ENSG00000115084.11,SLC35F5LUSCAUY922EAG3.4467e-06-0.2098image
chr2:113707519-113708753:-LUSCAUY922EER6.4793e-06-0.2048image
chr2:113707519-113708753:-MESOGSK269962AEER2.5141e-04-0.3961image
chr2:113709801-113710797:-MESOBMS.536924EER2.6029e-05-0.4770image
ENSG00000115084.11,SLC35F5MESOA.770041EAG6.7451e-04-0.3700image
chr2:113709801-113710797:-OVBexaroteneEER4.4185e-070.3277image
ENSG00000115084.11,SLC35F5OVGW843682XEAG1.5703e-03-0.1868image
chr2:113712283-113712631:-OVAS601245EER1.2568e-03-0.2935image
chr2:113707519-113708753:-OVCCT007093EER1.1110e-030.1929image
chr2:113709801-113710797:-PAADA.770041EER2.5108e-03-0.2373image
ENSG00000115084.11,SLC35F5PAADCamptothecinEAG6.0904e-04-0.2595image
chr2:113707519-113708753:-PAADCamptothecinEER3.5934e-03-0.2215image
chr2:113709801-113710797:-PCPGAZD6482EER1.2590e-040.3090image
ENSG00000115084.11,SLC35F5PCPGDMOGEAG1.7451e-04-0.2793image
chr2:113707519-113708753:-PCPGDMOGEER1.7328e-02-0.1797image
chr2:113709801-113710797:-PRADEmbelinEER9.3288e-110.3017image
ENSG00000115084.11,SLC35F5PRADBAY.61.3606EAG4.2884e-060.2051image
chr2:113707519-113708753:-PRADGefitinibEER1.3943e-04-0.1713image
chr2:113707519-113708753:-READCCT018159EER2.8971e-03-0.3040image
chr2:113709801-113710797:-READEmbelinEER7.1059e-030.2789image
ENSG00000115084.11,SLC35F5READBMS.708163EAG1.5266e-03-0.3208image
chr2:113709801-113710797:-SARCCI.1040EER7.2333e-08-0.3749image
ENSG00000115084.11,SLC35F5SARCBortezomibEAG3.2167e-03-0.1914image
chr2:113707519-113708753:-SARCFH535EER1.6288e-020.1572image
chr2:113709801-113710797:-SKCMAZD6244EER1.4050e-05-0.2177image
ENSG00000115084.11,SLC35F5SKCMAZD6244EAG4.9830e-08-0.2568image
chr2:113707519-113708753:-SKCMAZD6244EER7.0157e-06-0.2153image
chr2:113709801-113710797:-STADBMS.509744EER3.0398e-04-0.1904image
ENSG00000115084.11,SLC35F5STADBMS.509744EAG1.0850e-05-0.2283image
chr2:113740444-113741867:-STADABT.263EER1.3265e-020.2494image
chr2:113712283-113712631:-STADGemcitabineEER9.2026e-03-0.1538image
chr2:113707519-113708753:-STADBMS.509744EER1.0896e-05-0.2364image
chr2:113709801-113710797:-TGCTBortezomibEER1.8483e-040.3905image
ENSG00000115084.11,SLC35F5TGCTBortezomibEAG2.1482e-040.3474image
chr2:113707519-113708753:-TGCTGSK269962AEER3.0621e-040.3571image
chr2:113707519-113708753:-THCABAY.61.3606EER3.5587e-070.2258image
chr2:113709801-113710797:-THCABMS.536924EER3.3995e-19-0.3994image
ENSG00000115084.11,SLC35F5THCAEmbelinEAG1.6965e-130.3216image
chr2:113707519-113708753:-THYMAKT.inhibitor.VIIIEER4.6037e-020.2086image
chr2:113709801-113710797:-THYMGDC.0449EER3.4885e-05-0.5075image
chr2:113707519-113708753:-UCECMetforminEER4.7889e-02-0.1613image
chr2:113709801-113710797:-UCECEmbelinEER3.1134e-040.3451image
ENSG00000115084.11,SLC35F5UCECA.770041EAG5.2509e-09-0.4375image
chr2:113709801-113710797:-UCSAICAREER4.8999e-040.5584image
ENSG00000115084.11,SLC35F5UCSBMS.708163EAG1.5073e-020.3322image
chr2:113707519-113708753:-UCSEmbelinEER2.1772e-040.4870image
chr2:113707519-113708753:-UVMEmbelinEER4.6593e-030.3829image
chr2:113709801-113710797:-UVMBX.795EER2.4277e-02-0.3602image
ENSG00000115084.11,SLC35F5UVMEmbelinEAG2.0871e-030.4098image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType