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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: SRD5A1 (ImmuneEditome ID:6715)

1. Gene summary of enriched editing regions for SRD5A1

check button Gene summary
Gene informationGene symbol

SRD5A1

Gene ID

6715

GeneSynonymsS5AR 1
GeneCytomap

5p15.31

GeneTypeprotein-coding
GeneDescription3-oxo-5-alpha-steroid 4-dehydrogenase 1|SR type 1|steroid 5-alpha-reductase type I|steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
GeneModificationdate20230518
UniprotIDP18405;D6RDL6;D6RG03
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr5:6663609-6664665:+ENST00000274192.6ENSG00000145545.10SRD5A1intronicMIR3,AluSx1,AluJbchr5:6663609-6664665:+.alignment
chr5:6663609-6664665:+ENST00000510531.4ENSG00000145545.10SRD5A1intronicMIR3,AluSx1,AluJbchr5:6663609-6664665:+.alignment
chr5:6663609-6664665:+ENST00000513117.1ENSG00000145545.10SRD5A1intronicMIR3,AluSx1,AluJbchr5:6663609-6664665:+.alignment
chr5:6673349-6673705:+ENST00000274192.6ENSG00000145545.10SRD5A1UTR3L1MC2chr5:6673349-6673705:+.alignment


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2. Tumor-specific enriched editing regions for SRD5A1


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chr5:6673349-6673705:+KIRCEER4.2773e-02image
chr5:6673349-6673705:+LIHCEER1.3133e-02image
ENSG00000145545.10,SRD5A1LIHCEAG1.6744e-05image


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
ENSG00000145545.10,SRD5A1KIRCPathEAG1.7652e-029.3645e-030.1217image
chr5:6673349-6673705:+KIRCPathEER2.5282e-031.8234e-030.1489image


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
ENSG00000145545.10,SRD5A1KIRCEAG4.1156e-022.6795e-021.0862e+01image
ENSG00000145545.10,SRD5A1LUSCEAG8.6853e-043.9528e-031.2635e-02image

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3. Enriched editing regions and immune related genes for SRD5A1


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr5:6673349-6673705:+PCPGEERENSG00000084463,WBP11-0.38433.5037e-046.2113e-08-0.4244imageNEIF4A3;FUS;HNRNPC;IGF2BP2;MOV10;NOP56;RBM10;RBM47;U2AF2NAT_cells_CD4_memory_restingGSVA_HALLMARK_PROTEIN_SECRETION
chr5:6673349-6673705:+PCPGEERENSG00000227081,RP11-543P15.10.36649.1100e-043.5523e-090.4587imageNNNANK_cells_restingGSVA_HALLMARK_PROTEIN_SECRETION
chr5:6673349-6673705:+PCPGEERENSG00000163156,SCNM10.35071.5238e-032.0094e-070.4092imageNEIF4A3;FUS;HNRNPC;IGF2BP2;MOV10;NOP56;RBM10;U2AF2NAMast_cells_activatedGSVA_HALLMARK_PROTEIN_SECRETION
chr5:6673349-6673705:+PCPGEERENSG00000169715,MT1E0.32245.1288e-033.2541e-070.4026imageNEIF4A3;FUS;HNRNPC;RBM47;U2AF2NAGSVA_HALLMARK_XENOBIOTIC_METABOLISM
chr5:6673349-6673705:+PCPGEERENSG00000167641,PPP1R14A0.31805.9380e-038.9094e-090.4481imageNEIF4A3;FUS;IGF2BP2;U2AF2NANK_cells_activatedGSVA_HALLMARK_SPERMATOGENESIS
chr5:6673349-6673705:+PCPGEERENSG00000175287,PHYHD10.31606.4339e-034.9374e-080.4273imageNEIF4A3;FUS;HNRNPC;IGF2BP2;NOP56;U2AF2NAMacrophages_M2GSVA_HALLMARK_SPERMATOGENESIS
chr5:6673349-6673705:+PCPGEERENSG00000198467,TPM20.30518.3111e-033.7105e-090.4582imageNEIF4A3;FUS;HNRNPC;IGF2BP2;NOP56;RBM10;U2AF2NANK_cells_activatedGSVA_HALLMARK_MYOGENESIS
chr5:6673349-6673705:+PCPGEERENSG00000204136,GGTA1P0.29691.1287e-029.1834e-090.4478imageNNNANK_cells_activatedGSVA_HALLMARK_MYOGENESIS
chr5:6673349-6673705:+PCPGEERENSG00000239697,TNFSF120.29311.3653e-025.9677e-090.4528imageNEIF4A3;FUS;IGF2BP2TNFSF12T_cells_CD4_memory_restingGSVA_HALLMARK_PROTEIN_SECRETION
chr5:6673349-6673705:+PCPGEERENSG00000162496,DHRS30.28941.5340e-023.0492e-080.4333imageNEIF4A3;FUS;HNRNPC;IGF2BP2;MOV10;NOP56;U2AF2NAPlasma_cellsGSVA_HALLMARK_MYOGENESIS

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4. Enriched editing regions and immune related splicing for SRD5A1


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000145545.10,SRD5A1
GBMEAGIRENSG00000129657.10chr1777213917:77215958:77216098:77216101-0.29443.4814e-026.6964e-07-0.4002imageNACIN1;ADAR;AIFM1;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;MBNL2;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RNF219;SLBP;SLTM;SMNDC1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7BNAPlasma_cellsGSVA_HALLMARK_NOTCH_SIGNALING
ENSG00000145545.10,SRD5A1
PCPGEAGIRENSG00000130066.12chrX23783507:23783709:23783808:23783883-0.11211.4780e-024.3030e-08-0.4399imageNACIN1;ADAR;AIFM1;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;MBNL2;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;PRPF8;PTBP1;PUM2;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RNF219;SLBP;SLTM;SMNDC1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7BNAMacrophages_M0GSVA_HALLMARK_SPERMATOGENESIS
chr5:6673349-6673705:+
PCPGEERIRENSG00000115556.9chr2218633385:218633761:218634104:2186342210.35069.8701e-031.7822e-070.4107imageNEIF4A3;FUS;IGF2BP2;NOP56;RBM10;U2AF2PLCD4T_cells_CD4_memory_restingGSVA_HALLMARK_PROTEIN_SECRETION
chr5:6673349-6673705:+
PCPGEERIRENSG00000157514.12chrX107713220:107715950:107716314:1077165450.37372.0734e-037.5541e-080.4272imageNEIF4A3;FUS;HNRNPC;IGF2BP2;MOV10;NOP56;RBM10;U2AF2TSC22D3T_cells_CD4_memory_activatedGSVA_HALLMARK_SPERMATOGENESIS
chr5:6673349-6673705:+
PCPGEERIRENSG00000100949.10chr1424270836:24271169:24271486:242715100.34921.1579e-021.0838e-070.4173imageNEIF4A3;FUS;HNRNPC;IGF2BP2;MOV10;RBM10;U2AF2NAPlasma_cellsGSVA_HALLMARK_PROTEIN_SECRETION
chr5:6673349-6673705:+
PCPGEERIRENSG00000130066.12chrX23783507:23783709:23783808:23783883-0.11831.1681e-022.8282e-08-0.4571imageNEIF4A3;FUS;HNRNPC;IGF2BP2;MOV10;NOP56;RBM10;RBM47;U2AF2NAMacrophages_M0GSVA_HALLMARK_SPERMATOGENESIS

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5. Enriched editing regions and immune infiltration for SRD5A1


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chr5:6673349-6673705:+BRCAEERMacrophages_M01.5465e-02-0.1145image
ENSG00000145545.10,SRD5A1BRCAEAGMast_cells_resting7.2985e-030.1222image
ENSG00000145545.10,SRD5A1CESCEAGMonocytes1.2068e-020.2248image
ENSG00000145545.10,SRD5A1ESCAEAGDendritic_cells_activated3.2915e-02-0.2114image
ENSG00000145545.10,SRD5A1GBMEAGPlasma_cells2.2600e-040.3027image
ENSG00000145545.10,SRD5A1HNSCEAGDendritic_cells_resting1.3183e-02-0.1844image
ENSG00000145545.10,SRD5A1KICHEAGT_cells_CD4_memory_activated3.5228e-020.3924image
chr5:6673349-6673705:+KIRCEERT_cells_CD4_memory_activated8.3822e-040.1878image
ENSG00000145545.10,SRD5A1KIRCEAGT_cells_CD4_memory_activated3.5666e-040.1960image
ENSG00000145545.10,SRD5A1KIRPEAGEosinophils2.2463e-040.3944image
chr5:6673349-6673705:+LGGEERT_cells_CD82.9041e-04-0.1629image
ENSG00000145545.10,SRD5A1LGGEAGT_cells_CD4_memory_activated8.7740e-040.1480image
ENSG00000145545.10,SRD5A1LUADEAGNK_cells_resting4.3703e-02-0.1518image
ENSG00000145545.10,SRD5A1LUSCEAGT_cells_CD4_memory_activated9.8304e-030.1975image
chr5:6673349-6673705:+PCPGEERNeutrophils4.0271e-02-0.1677image
ENSG00000145545.10,SRD5A1PCPGEAGMacrophages_M07.3500e-030.2125image
ENSG00000145545.10,SRD5A1SARCEAGPlasma_cells1.2297e-040.3677image
chr5:6673349-6673705:+STADEERT_cells_CD4_memory_resting5.7522e-04-0.2770image
ENSG00000145545.10,SRD5A1STADEAGT_cells_CD4_memory_resting1.3708e-03-0.2464image
ENSG00000145545.10,SRD5A1THCAEAGMacrophages_M21.5506e-020.4119image
ENSG00000145545.10,SRD5A1THYMEAGT_cells_CD4_memory_resting4.2997e-020.3998image


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6. Enriched editing regions and immune gene sets for SRD5A1


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot
ENSG00000145545.10,SRD5A1HNSCEAG1.3448e-02image5.3358e-030.2068image


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
ENSG00000145545.10,SRD5A1BLCAGSVA_HALLMARK_MYOGENESISEAG7.0891e-03-0.2988image
ENSG00000145545.10,SRD5A1BRCAGSVA_HALLMARK_MYOGENESISEAG1.5540e-030.1439image
chr5:6673349-6673705:+BRCAGSVA_HALLMARK_MYOGENESISEER1.2841e-030.1518image
ENSG00000145545.10,SRD5A1CHOLGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG3.4757e-030.5618image
ENSG00000145545.10,SRD5A1COADGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKBEAG3.0745e-020.4018image
ENSG00000145545.10,SRD5A1ESCAGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEAG1.3368e-02-0.2442image
ENSG00000145545.10,SRD5A1GBMGSVA_HALLMARK_HEDGEHOG_SIGNALINGEAG1.3143e-03-0.2652image
ENSG00000145545.10,SRD5A1HNSCGSVA_HALLMARK_HYPOXIAEAG1.2201e-040.2825image
ENSG00000145545.10,SRD5A1KICHGSVA_HALLMARK_MTORC1_SIGNALINGEAG1.9180e-03-0.5517image
chr5:6673349-6673705:+KIRCGSVA_HALLMARK_MYC_TARGETS_V2EER6.8753e-030.1525image
ENSG00000145545.10,SRD5A1KIRCGSVA_HALLMARK_E2F_TARGETSEAG7.6759e-030.1470image
chr5:6673349-6673705:+LGGGSVA_HALLMARK_HEDGEHOG_SIGNALINGEER7.6575e-04-0.1514image
ENSG00000145545.10,SRD5A1LGGGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG4.2323e-040.1568image
ENSG00000145545.10,SRD5A1LIHCGSVA_HALLMARK_MYC_TARGETS_V2EAG3.9803e-040.2084image
chr5:6673349-6673705:+LIHCGSVA_HALLMARK_MYC_TARGETS_V2EER5.2110e-040.2079image
chr5:6673349-6673705:+LUADGSVA_HALLMARK_MYOGENESISEER3.4426e-020.1643image
ENSG00000145545.10,SRD5A1LUSCGSVA_HALLMARK_P53_PATHWAYEAG1.1861e-02-0.1926image
ENSG00000145545.10,SRD5A1MESOGSVA_HALLMARK_PEROXISOMEEAG5.4610e-03-0.4661image
ENSG00000145545.10,SRD5A1OVGSVA_HALLMARK_KRAS_SIGNALING_UPEAG4.9739e-020.2135image
ENSG00000145545.10,SRD5A1PAADGSVA_HALLMARK_SPERMATOGENESISEAG3.5866e-03-0.3968image
ENSG00000145545.10,SRD5A1PCPGGSVA_HALLMARK_PROTEIN_SECRETIONEAG8.7665e-03-0.2079image
chr5:6673349-6673705:+PCPGGSVA_HALLMARK_PROTEIN_SECRETIONEER4.3542e-04-0.2837image
ENSG00000145545.10,SRD5A1SKCMGSVA_HALLMARK_UV_RESPONSE_UPEAG1.8212e-030.2493image
chr5:6673349-6673705:+STADGSVA_HALLMARK_ALLOGRAFT_REJECTIONEER5.0535e-040.2797image
ENSG00000145545.10,SRD5A1STADGSVA_HALLMARK_PROTEIN_SECRETIONEAG8.1212e-03-0.2048image
ENSG00000145545.10,SRD5A1THYMGSVA_HALLMARK_UV_RESPONSE_DNEAG2.4974e-030.5675image


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7. Enriched editing regions and drugs for SRD5A1


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
ENSG00000145545.10,SRD5A1BLCAA.770041EAG2.1603e-040.4023image
ENSG00000145545.10,SRD5A1BRCAABT.263EAG3.4049e-030.1336image
chr5:6673349-6673705:+BRCAABT.263EER6.2822e-040.1615image
ENSG00000145545.10,SRD5A1CHOLDoxorubicinEAG1.9693e-02-0.4633image
ENSG00000145545.10,SRD5A1COADGefitinibEAG1.9267e-02-0.4320image
ENSG00000145545.10,SRD5A1ESCABIBW2992EAG3.7348e-050.3963image
ENSG00000145545.10,SRD5A1GBMFTI.277EAG4.0517e-040.2909image
ENSG00000145545.10,SRD5A1HNSCAZD7762EAG2.1993e-03-0.2268image
chr5:6673349-6673705:+KIRCBI.D1870EER3.9876e-06-0.2573image
ENSG00000145545.10,SRD5A1KIRCCamptothecinEAG4.7414e-05-0.2226image
ENSG00000145545.10,SRD5A1KIRPDoxorubicinEAG1.7173e-02-0.2610image
chr5:6673349-6673705:+LGGErlotinibEER6.0298e-06-0.2026image
ENSG00000145545.10,SRD5A1LGGAKT.inhibitor.VIIIEAG1.2478e-04-0.1704image
ENSG00000145545.10,SRD5A1LIHCKU.55933EAG1.1700e-020.1497image
chr5:6673349-6673705:+LIHCBI.2536EER6.4865e-030.1638image
ENSG00000145545.10,SRD5A1LUADAG.014699EAG1.4226e-02-0.1840image
chr5:6673349-6673705:+LUADABT.888EER4.3428e-020.1570image
ENSG00000145545.10,SRD5A1LUSCLFM.A13EAG5.9342e-050.3029image
ENSG00000145545.10,SRD5A1MESOAZD.0530EAG2.8357e-06-0.7079image
ENSG00000145545.10,SRD5A1OVLapatinibEAG2.5215e-02-0.2427image
ENSG00000145545.10,SRD5A1PAADBryostatin.1EAG1.9769e-03-0.4231image
ENSG00000145545.10,SRD5A1PCPGA.770041EAG7.2951e-06-0.3494image
chr5:6673349-6673705:+PCPGA.770041EER3.0139e-05-0.3347image
ENSG00000145545.10,SRD5A1PRADEtoposideEAG1.4163e-02-0.2880image
ENSG00000145545.10,SRD5A1SARCAKT.inhibitor.VIIIEAG6.0646e-04-0.3307image
ENSG00000145545.10,SRD5A1SKCMJW.7.52.1EAG2.2569e-03-0.2444image
chr5:6673349-6673705:+STADGDC0941EER1.8560e-03-0.2513image
ENSG00000145545.10,SRD5A1STADGDC0941EAG9.5111e-03-0.2007image
ENSG00000145545.10,SRD5A1THCABexaroteneEAG3.1192e-04-0.5813image
ENSG00000145545.10,SRD5A1THYMBI.D1870EAG1.4589e-040.6770image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType
chr5:6663609-6664665:+ENST00000274192.6P18405DB00367LevonorgestrelSmallMoleculeDrug
chr5:6663609-6664665:+ENST00000274192.6P18405DB00421SpironolactoneSmallMoleculeDrug
chr5:6663609-6664665:+ENST00000274192.6P18405DB01126DutasterideSmallMoleculeDrug
chr5:6663609-6664665:+ENST00000274192.6P18405DB01216FinasterideSmallMoleculeDrug
chr5:6663609-6664665:+ENST00000274192.6P18405DB09389NorgestrelSmallMoleculeDrug
chr5:6673349-6673705:+ENST00000274192.6P18405DB00367LevonorgestrelSmallMoleculeDrug
chr5:6673349-6673705:+ENST00000274192.6P18405DB00421SpironolactoneSmallMoleculeDrug
chr5:6673349-6673705:+ENST00000274192.6P18405DB01126DutasterideSmallMoleculeDrug
chr5:6673349-6673705:+ENST00000274192.6P18405DB01216FinasterideSmallMoleculeDrug
chr5:6673349-6673705:+ENST00000274192.6P18405DB09389NorgestrelSmallMoleculeDrug