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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: XPNPEP3 (ImmuneEditome ID:63929)

1. Gene summary of enriched editing regions for XPNPEP3

check button Gene summary
Gene informationGene symbol

XPNPEP3

Gene ID

63929

GeneSynonymsAPP3|ICP55|NPHPL1
GeneCytomap

22q13.2

GeneTypeprotein-coding
GeneDescriptionxaa-Pro aminopeptidase 3|Intermediate Cleaving Peptidase 55|X-Pro aminopeptidase 3|X-prolyl aminopeptidase 3, mitochondrial|probable Xaa-Pro aminopeptidase 3
GeneModificationdate20230518
UniprotIDQ9NQH7;A0A087X0Z2;F2Z316
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr22:40888269-40891172:+ENST00000357137.7ENSG00000196236.11XPNPEP3intronicAluJb,AluJr4,L1MB4chr22:40888269-40891172:+.alignment
chr22:40888269-40891172:+ENST00000428799.1ENSG00000196236.11XPNPEP3intronicAluJb,AluJr4,L1MB4chr22:40888269-40891172:+.alignment
chr22:40927169-40931738:+ENST00000357137.7ENSG00000196236.11XPNPEP3UTR3AluJr,AluSz6,AluSx3,AluSg7,AluSc5,AluYm1,L1MA5A,AluSc8chr22:40927169-40931738:+.alignment
chr22:40927169-40931738:+ENST00000428799.1ENSG00000196236.11XPNPEP3UTR3AluJr,AluSz6,AluSx3,AluSg7,AluSc5,AluYm1,L1MA5A,AluSc8chr22:40927169-40931738:+.alignment


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2. Tumor-specific enriched editing regions for XPNPEP3


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chr22:40927169-40931738:+BRCAEER1.6457e-02image
ENSG00000196236.11,XPNPEP3BRCAEAG1.5626e-02image
chr22:40927169-40931738:+KICHEER1.8233e-04image
ENSG00000196236.11,XPNPEP3KICHEAG2.0300e-04image
ENSG00000196236.11,XPNPEP3KIRCEAG3.0760e-02image
chr22:40927169-40931738:+KIRPEER4.7700e-02image
ENSG00000196236.11,XPNPEP3KIRPEAG4.7700e-02image
chr22:40927169-40931738:+LIHCEER3.6635e-02image
ENSG00000196236.11,XPNPEP3LIHCEAG3.6693e-02image
chr22:40927169-40931738:+THCAEER7.3145e-08image
ENSG00000196236.11,XPNPEP3THCAEAG7.0131e-08image


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
chr22:40927169-40931738:+ESCAPathEER4.9888e-021.3160e-020.2069image
ENSG00000196236.11,XPNPEP3ESCAPathEAG4.7943e-021.2404e-020.2086image
chr22:40888269-40891172:+STADPathEER3.5598e-034.5424e-020.3356image


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
chr22:40927169-40931738:+KIRCEER2.6395e-023.7106e-021.0630e+01image
ENSG00000196236.11,XPNPEP3KIRCEAG2.6395e-023.7089e-021.0632e+01image
chr22:40927169-40931738:+STADEER1.4623e-023.0007e-021.2779e+01image

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3. Enriched editing regions and immune related genes for XPNPEP3


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr22:40927169-40931738:+GBMEERENSG00000102096,PIM20.44871.7252e-051.6245e-090.4661imageNTARDBP;ADAR;CELF2;CSTF2T;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TIA1;U2AF2PIM2Plasma_cellsGSVA_HALLMARK_BILE_ACID_METABOLISM
chr22:40927169-40931738:+GBMEERENSG00000196236,XPNPEP3-0.38674.2843e-041.2578e-07-0.4141imageNTARDBP;ADAR;CELF2;CSTF2T;DHX9;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TARBP2;TIA1;U2AF2NAMonocytesGSVA_HALLMARK_UV_RESPONSE_UP
chr22:40927169-40931738:+STADEERENSG00000196236,XPNPEP3-0.44155.4602e-142.0069e-17-0.4307imageNTARDBP;ADAR;CELF2;CSTF2T;DHX9;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TARBP2;TIA1;U2AF2NAMonocytesGSVA_HALLMARK_PANCREAS_BETA_CELLS
chr22:40927169-40931738:+UCECEERENSG00000168216,LMBRD10.34823.5427e-035.8779e-080.4127imageNTARDBP;ADAR;CELF2;CSTF2T;DHX9;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TIA1;U2AF2NAT_cells_CD4_memory_restingGSVA_HALLMARK_PROTEIN_SECRETION
chr22:40927169-40931738:+TGCTEERENSG00000164182,NDUFAF20.39111.7242e-049.9950e-070.4079imageNTARDBP;ADAR;CELF2;CSTF2T;DHX9;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;MSI1;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TARBP2;TIA1;U2AF2NAB_cells_naiveGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr22:40927169-40931738:+TGCTEERENSG00000137944,CCBL20.39402.3201e-049.9064e-070.4080imageNTARDBP;ADAR;CELF2;CSTF2T;DHX9;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;MSI1;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TARBP2;TIA1;U2AF2NAB_cells_naiveGSVA_HALLMARK_ESTROGEN_RESPONSE_EARLY
chr22:40927169-40931738:+TGCTEERENSG00000184481,FOXO40.38143.4006e-043.0925e-070.4250imageNTARDBP;ADAR;CELF2;CSTF2T;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;IGF2BP2;MOV10;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TIA1;U2AF2NAMacrophages_M2GSVA_HALLMARK_ESTROGEN_RESPONSE_EARLY
chr22:40927169-40931738:+TGCTEERENSG00000090013,BLVRB0.31115.1874e-031.6192e-060.4006imageNTARDBP;ADAR;CSTF2T;DHX9;EIF4A3;ELAVL1;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;MSI1;NOP56;NOP58;PTBP1;RBFOX2;TAF15;TARBP2;U2AF2NAB_cells_naiveGSVA_HALLMARK_COAGULATION
chr22:40927169-40931738:+TGCTEERENSG00000170469,SPATA240.30305.4692e-038.2433e-080.4431imageNTARDBP;CSTF2T;DHX9;EIF4A3;ELAVL1;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;IGF2BP2;MOV10;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TARBP2;TIA1;U2AF2NADendritic_cells_restingGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr22:40927169-40931738:+TGCTEERENSG00000118245,TNP10.27627.8384e-031.0500e-070.4399imageNTAF15NADendritic_cells_restingGSVA_HALLMARK_SPERMATOGENESIS
chr22:40927169-40931738:+GBMEERENSG00000102096,PIM20.44871.7252e-051.6245e-090.4661imageNTARDBP;ADAR;CELF2;CSTF2T;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TIA1;U2AF2PIM2Plasma_cellsGSVA_HALLMARK_BILE_ACID_METABOLISM
chr22:40927169-40931738:+GBMEERENSG00000196236,XPNPEP3-0.38674.2843e-041.2578e-07-0.4141imageNTARDBP;ADAR;CELF2;CSTF2T;DHX9;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TARBP2;TIA1;U2AF2NAMonocytesGSVA_HALLMARK_UV_RESPONSE_UP
chr22:40927169-40931738:+STADEERENSG00000196236,XPNPEP3-0.44155.4602e-142.0069e-17-0.4307imageNTARDBP;ADAR;CELF2;CSTF2T;DHX9;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TARBP2;TIA1;U2AF2NAMonocytesGSVA_HALLMARK_PANCREAS_BETA_CELLS
chr22:40927169-40931738:+UCECEERENSG00000168216,LMBRD10.34823.5427e-035.8779e-080.4127imageNTARDBP;ADAR;CELF2;CSTF2T;DHX9;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TIA1;U2AF2NAT_cells_CD4_memory_restingGSVA_HALLMARK_PROTEIN_SECRETION
chr22:40927169-40931738:+TGCTEERENSG00000164182,NDUFAF20.39111.7242e-049.9950e-070.4079imageNTARDBP;ADAR;CELF2;CSTF2T;DHX9;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;MSI1;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TARBP2;TIA1;U2AF2NAB_cells_naiveGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr22:40927169-40931738:+TGCTEERENSG00000137944,CCBL20.39402.3201e-049.9064e-070.4080imageNTARDBP;ADAR;CELF2;CSTF2T;DHX9;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;MSI1;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TARBP2;TIA1;U2AF2NAB_cells_naiveGSVA_HALLMARK_ESTROGEN_RESPONSE_EARLY
chr22:40927169-40931738:+TGCTEERENSG00000184481,FOXO40.38143.4006e-043.0925e-070.4250imageNTARDBP;ADAR;CELF2;CSTF2T;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;IGF2BP2;MOV10;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TIA1;U2AF2NAMacrophages_M2GSVA_HALLMARK_ESTROGEN_RESPONSE_EARLY
chr22:40927169-40931738:+TGCTEERENSG00000090013,BLVRB0.31115.1874e-031.6192e-060.4006imageNTARDBP;ADAR;CSTF2T;DHX9;EIF4A3;ELAVL1;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;MSI1;NOP56;NOP58;PTBP1;RBFOX2;TAF15;TARBP2;U2AF2NAB_cells_naiveGSVA_HALLMARK_COAGULATION
chr22:40927169-40931738:+TGCTEERENSG00000170469,SPATA240.30305.4692e-038.2433e-080.4431imageNTARDBP;CSTF2T;DHX9;EIF4A3;ELAVL1;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;IGF2BP2;MOV10;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TARBP2;TIA1;U2AF2NADendritic_cells_restingGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr22:40927169-40931738:+TGCTEERENSG00000118245,TNP10.27627.8384e-031.0500e-070.4399imageNTAF15NADendritic_cells_restingGSVA_HALLMARK_SPERMATOGENESIS

More results



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4. Enriched editing regions and immune related splicing for XPNPEP3


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000196236.11,XPNPEP3
COADEAGESENSG00000138641.11chr488676333:88676423:88677963:88678134:88680092:88680236-0.17971.9423e-024.0937e-08-0.4124imageNADAR;ALYREF;AUH;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM47;RC3H1;SAFB2;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDF1;ZNF184NAEosinophilsGSVA_HALLMARK_PEROXISOME
chr22:40927169-40931738:+
COADEERESENSG00000138641.11chr488676333:88676423:88677963:88678134:88680092:88680236-0.18601.1542e-023.3431e-08-0.4160imageNTARDBP;ADAR;CELF2;CSTF2T;DHX9;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;MSI1;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TIA1;U2AF2NAEosinophilsGSVA_HALLMARK_PEROXISOME
chr22:40927169-40931738:+
GBMEERIRENSG00000171962.13chr1718004362:18004494:18006182:18006253-0.31894.3515e-038.7862e-07-0.4380imageNTARDBP;ADAR;EIF4A3;ELAVL1;FBL;FUS;HNRNPA1;HNRNPC;HNRNPL;IGF2BP2;NOP56;NOP58;RBFOX2;TAF15;U2AF2NAMacrophages_M0GSVA_HALLMARK_BILE_ACID_METABOLISM
ENSG00000196236.11,XPNPEP3
GBMEAGIRENSG00000171962.13chr1718004362:18004494:18006182:18006253-0.31964.8883e-038.4157e-07-0.4387imageNADAR;DGCR8;DKC1;EIF4A3;ELAVL1;EWSR1;FBL;FMR1;FUS;HNRNPA1;HNRNPC;HNRNPL;IGF2BP1;IGF2BP2;KHDRBS1;LIN28;LIN28B;NOP56;NOP58;RANGAP1;RBFOX2;RBM10;SMNDC1;SND1;SRSF1;TAF15;TARDBP;TROVE2;U2AF1;U2AF2;UPF1;YTHDF1;ZNF184NAMacrophages_M0GSVA_HALLMARK_BILE_ACID_METABOLISM
ENSG00000196236.11,XPNPEP3
TGCTEAGIRENSG00000104218.9chr867190649:67190759:67193463:67193577-0.37142.4064e-031.4397e-06-0.4125imageNACIN1;ADAR;ALYREF;AUH;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FUS;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM47;RBM5;SAFB2;SF3A3;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;ZC3H7B;ZNF184NAB_cells_naiveGSVA_HALLMARK_UV_RESPONSE_UP
chr22:40927169-40931738:+
TGCTEERESENSG00000123562.12chrX103676978:103677051:103678498:103678620:103685170:103685260-0.33994.3647e-033.5765e-06-0.4119imageNTARDBP;ADAR;CELF2;CSTF2T;DHX9;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;MSI1;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TIA1;U2AF2NAMacrophages_M2GSVA_HALLMARK_ESTROGEN_RESPONSE_LATE
ENSG00000196236.11,XPNPEP3
TGCTEAGIRENSG00000100429.13chr2250247889:50248472:50249102:50249168-0.24542.9423e-028.7785e-06-0.4133imageNADAR;ALYREF;AUH;BUD13;CELF2;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DICER1;EIF4A3;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHSRP;LARP4B;LIN28;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM27;SAFB2;SF3A3;SLTM;SMNDC1;SND1;SRSF1;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TNRC6A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;ZNF184NAT_cells_CD4_naiveGSVA_HALLMARK_GLYCOLYSIS
chr22:40927169-40931738:+
TGCTEERIRENSG00000104218.9chr867190649:67190759:67193463:67193577-0.37222.7969e-031.3961e-06-0.4130imageNTARDBP;ADAR;CELF2;CSTF2T;DHX9;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;IGF2BP2;MOV10;MSI1;NOP56;NOP58;PTBP1;RBFOX2;SRSF3;TAF15;TARBP2;TIA1;U2AF2NAB_cells_naiveGSVA_HALLMARK_UV_RESPONSE_UP
chr22:40927169-40931738:+
TGCTEERESENSG00000162976.8chr211172011:11172045:11174967:11175009:11177736:11177904-0.34361.3448e-021.4113e-07-0.4374imageNTARDBP;ADAR;CELF2;CSTF2T;DHX9;EIF4A3;ELAVL1;ELAVL3;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;IGF2BP2;NOP58;PTBP1;RBFOX2;TAF15;U2AF2NAB_cells_naiveGSVA_HALLMARK_PANCREAS_BETA_CELLS
ENSG00000196236.11,XPNPEP3
TGCTEAGESENSG00000162976.8chr211172011:11172045:11174967:11175009:11177736:11177904-0.34381.2198e-021.3850e-07-0.4376imageNACIN1;ADAR;CELF2;CNBP;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;FAM120A;FBL;FUS;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;ILF3;KHDRBS1;KHDRBS2;KHSRP;LIN28B;MSI2;NONO;NOP58;PRPF8;PTBP1;RBFOX2;RBM47;SMNDC1;SND1;SRSF1;TAF15;TARDBP;TIAL1;U2AF1;U2AF2;UPF1NAB_cells_naiveGSVA_HALLMARK_PANCREAS_BETA_CELLS

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5. Enriched editing regions and immune infiltration for XPNPEP3


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chr22:40927169-40931738:+BLCAEERMacrophages_M12.8317e-020.1171image
ENSG00000196236.11,XPNPEP3BLCAEAGMacrophages_M12.8317e-020.1171image
chr22:40927169-40931738:+BRCAEEREosinophils6.9029e-030.0828image
ENSG00000196236.11,XPNPEP3BRCAEAGEosinophils6.5602e-030.0833image
chr22:40927169-40931738:+CHOLEERT_cells_CD4_memory_activated6.7661e-040.5468image
ENSG00000196236.11,XPNPEP3CHOLEAGT_cells_CD4_memory_activated7.1196e-040.5449image
chr22:40927169-40931738:+COADEERDendritic_cells_activated3.4646e-020.1403image
ENSG00000196236.11,XPNPEP3COADEAGDendritic_cells_activated3.8519e-020.1372image
chr22:40927169-40931738:+DLBCEERNK_cells_resting1.9476e-020.3680image
ENSG00000196236.11,XPNPEP3DLBCEAGNK_cells_resting1.9476e-020.3680image
chr22:40927169-40931738:+ESCAEERMacrophages_M28.1685e-040.2612image
ENSG00000196236.11,XPNPEP3ESCAEAGMacrophages_M28.9000e-040.2594image
chr22:40927169-40931738:+GBMEERMonocytes1.8613e-030.2512image
ENSG00000196236.11,XPNPEP3GBMEAGMonocytes1.7924e-030.2521image
chr22:40927169-40931738:+HNSCEERNK_cells_activated1.9821e-02-0.1134image
ENSG00000196236.11,XPNPEP3HNSCEAGNK_cells_activated1.9821e-02-0.1134image
chr22:40927169-40931738:+KICHEERMonocytes1.5063e-030.3886image
ENSG00000196236.11,XPNPEP3KICHEAGMonocytes1.5063e-030.3886image
chr22:40927169-40931738:+KIRCEERT_cells_follicular_helper3.3977e-030.1527image
ENSG00000196236.11,XPNPEP3KIRCEAGT_cells_follicular_helper3.4023e-030.1527image
chr22:40927169-40931738:+KIRPEERT_cells_CD4_memory_activated1.5776e-030.1894image
ENSG00000196236.11,XPNPEP3KIRPEAGT_cells_CD4_memory_activated1.5776e-030.1894image
chr22:40927169-40931738:+LGGEERMacrophages_M01.4097e-03-0.1417image
ENSG00000196236.11,XPNPEP3LGGEAGMacrophages_M01.4288e-03-0.1415image
chr22:40927169-40931738:+LIHCEERNK_cells_activated1.7610e-03-0.1676image
ENSG00000196236.11,XPNPEP3LIHCEAGNK_cells_activated1.7687e-03-0.1675image
chr22:40927169-40931738:+LUADEERPlasma_cells4.4906e-03-0.1348image
ENSG00000196236.11,XPNPEP3LUADEAGPlasma_cells4.0787e-03-0.1360image
chr22:40927169-40931738:+LUSCEERPlasma_cells7.7063e-030.1236image
ENSG00000196236.11,XPNPEP3LUSCEAGPlasma_cells7.6104e-030.1238image
chr22:40888269-40891172:+OVEERMonocytes1.3461e-020.4971image
chr22:40927169-40931738:+OVEERT_cells_CD81.1109e-030.1915image
ENSG00000196236.11,XPNPEP3OVEAGT_cells_CD81.1063e-030.1916image
chr22:40927169-40931738:+PAADEERMacrophages_M02.0807e-020.1905image
ENSG00000196236.11,XPNPEP3PAADEAGMacrophages_M02.0807e-020.1905image
chr22:40927169-40931738:+PRADEEREosinophils4.6326e-020.0912image
ENSG00000196236.11,XPNPEP3PRADEAGEosinophils4.6362e-020.0912image
chr22:40927169-40931738:+SARCEERNK_cells_resting5.9832e-03-0.1784image
ENSG00000196236.11,XPNPEP3SARCEAGNK_cells_resting5.9832e-03-0.1784image
chr22:40927169-40931738:+SKCMEERT_cells_CD87.4413e-050.1916image
ENSG00000196236.11,XPNPEP3SKCMEAGT_cells_CD87.0056e-050.1923image
chr22:40888269-40891172:+STADEERT_cells_CD4_memory_resting1.9395e-020.3729image
chr22:40927169-40931738:+STADEERT_cells_CD4_memory_activated3.4512e-020.1124image
ENSG00000196236.11,XPNPEP3STADEAGT_cells_CD4_memory_activated4.1560e-020.1084image
chr22:40927169-40931738:+TGCTEERMonocytes2.6378e-030.2578image
ENSG00000196236.11,XPNPEP3TGCTEAGMonocytes2.6273e-030.2579image
chr22:40927169-40931738:+THCAEERDendritic_cells_resting3.0428e-050.2013image
ENSG00000196236.11,XPNPEP3THCAEAGDendritic_cells_resting2.8592e-050.2020image
chr22:40927169-40931738:+THYMEERMacrophages_M18.3826e-030.2513image
ENSG00000196236.11,XPNPEP3THYMEAGMacrophages_M18.3826e-030.2513image
ENSG00000196236.11,XPNPEP3UCSEAGNK_cells_resting1.7736e-040.5155image


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6. Enriched editing regions and immune gene sets for XPNPEP3


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot
chr22:40927169-40931738:+LIHCEER4.5309e-020.10772.8213e-020.11802.8625e-020.11773.3761e-020.1142image
ENSG00000196236.11,XPNPEP3LIHCEAG4.5106e-020.10782.8282e-020.11792.8340e-020.11793.3746e-020.1142image


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
ENSG00000196236.11,XPNPEP3ACCGSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALINGEAG3.6922e-020.2447image
chr22:40927169-40931738:+ACCGSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALINGEER3.6922e-020.2447image
ENSG00000196236.11,XPNPEP3BLCAGSVA_HALLMARK_HYPOXIAEAG2.2091e-030.1628image
chr22:40927169-40931738:+BLCAGSVA_HALLMARK_HYPOXIAEER2.2091e-030.1628image
ENSG00000196236.11,XPNPEP3BRCAGSVA_HALLMARK_APOPTOSISEAG4.5235e-080.1668image
chr22:40927169-40931738:+BRCAGSVA_HALLMARK_APOPTOSISEER2.2260e-080.1705image
chr22:40927169-40931738:+CESCGSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALINGEER1.3764e-030.1948image
ENSG00000196236.11,XPNPEP3CESCGSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALINGEAG1.3957e-030.1946image
ENSG00000196236.11,XPNPEP3CHOLGSVA_HALLMARK_SPERMATOGENESISEAG1.7345e-020.3998image
chr22:40927169-40931738:+CHOLGSVA_HALLMARK_SPERMATOGENESISEER1.5424e-020.4064image
chr22:40927169-40931738:+COADGSVA_HALLMARK_INFLAMMATORY_RESPONSEEER1.4364e-030.2103image
ENSG00000196236.11,XPNPEP3COADGSVA_HALLMARK_INFLAMMATORY_RESPONSEEAG1.2745e-030.2121image
chr22:40927169-40931738:+ESCAGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER1.1171e-050.3386image
ENSG00000196236.11,XPNPEP3ESCAGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG1.1089e-050.3387image
chr22:40927169-40931738:+GBMGSVA_HALLMARK_XENOBIOTIC_METABOLISMEER2.5524e-030.2438image
ENSG00000196236.11,XPNPEP3GBMGSVA_HALLMARK_XENOBIOTIC_METABOLISMEAG2.5087e-030.2442image
chr22:40927169-40931738:+HNSCGSVA_HALLMARK_APOPTOSISEER1.5502e-050.2087image
ENSG00000196236.11,XPNPEP3HNSCGSVA_HALLMARK_APOPTOSISEAG1.5502e-050.2087image
chr22:40927169-40931738:+KICHGSVA_HALLMARK_MYC_TARGETS_V2EER5.4247e-03-0.3437image
ENSG00000196236.11,XPNPEP3KICHGSVA_HALLMARK_MYC_TARGETS_V2EAG5.4247e-03-0.3437image
ENSG00000196236.11,XPNPEP3KIRCGSVA_HALLMARK_ALLOGRAFT_REJECTIONEAG2.3804e-040.1910image
chr22:40927169-40931738:+KIRCGSVA_HALLMARK_ALLOGRAFT_REJECTIONEER2.3698e-040.1910image
chr22:40927169-40931738:+KIRPGSVA_HALLMARK_ALLOGRAFT_REJECTIONEER1.5405e-030.1898image
ENSG00000196236.11,XPNPEP3KIRPGSVA_HALLMARK_ALLOGRAFT_REJECTIONEAG1.5405e-030.1898image
chr22:40927169-40931738:+LGGGSVA_HALLMARK_MYOGENESISEER2.2188e-060.2088image
ENSG00000196236.11,XPNPEP3LGGGSVA_HALLMARK_MYOGENESISEAG2.4568e-060.2079image
ENSG00000196236.11,XPNPEP3LIHCGSVA_HALLMARK_PROTEIN_SECRETIONEAG8.4377e-060.2369image
chr22:40927169-40931738:+LIHCGSVA_HALLMARK_PROTEIN_SECRETIONEER8.5716e-060.2367image
ENSG00000196236.11,XPNPEP3LUADGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKBEAG1.2195e-040.1813image
chr22:40927169-40931738:+LUADGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKBEER1.7868e-040.1771image
chr22:40927169-40931738:+LUSCGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER4.7884e-060.2105image
ENSG00000196236.11,XPNPEP3LUSCGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG4.8778e-060.2104image
ENSG00000196236.11,XPNPEP3MESOGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG1.7955e-020.2863image
chr22:40927169-40931738:+OVGSVA_HALLMARK_DNA_REPAIREER8.0922e-040.1966image
ENSG00000196236.11,XPNPEP3OVGSVA_HALLMARK_DNA_REPAIREAG8.5617e-040.1957image
ENSG00000196236.11,XPNPEP3PAADGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG3.9032e-020.1704image
chr22:40927169-40931738:+PAADGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER3.9032e-020.1704image
chr22:40927169-40931738:+PCPGGSVA_HALLMARK_PROTEIN_SECRETIONEER8.7269e-030.2156image
ENSG00000196236.11,XPNPEP3PCPGGSVA_HALLMARK_PROTEIN_SECRETIONEAG8.7269e-030.2156image
chr22:40927169-40931738:+PRADGSVA_HALLMARK_UNFOLDED_PROTEIN_RESPONSEEER2.0919e-04-0.1688image
ENSG00000196236.11,XPNPEP3PRADGSVA_HALLMARK_UNFOLDED_PROTEIN_RESPONSEEAG1.9494e-04-0.1696image
ENSG00000196236.11,XPNPEP3READGSVA_HALLMARK_TGF_BETA_SIGNALINGEAG3.1226e-030.3188image
chr22:40927169-40931738:+READGSVA_HALLMARK_TGF_BETA_SIGNALINGEER3.1226e-030.3188image
ENSG00000196236.11,XPNPEP3SARCGSVA_HALLMARK_APOPTOSISEAG1.4209e-040.2452image
chr22:40927169-40931738:+SARCGSVA_HALLMARK_APOPTOSISEER1.4209e-040.2452image
chr22:40927169-40931738:+SKCMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.3734e-050.2099image
ENSG00000196236.11,XPNPEP3SKCMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG1.2650e-050.2108image
ENSG00000196236.11,XPNPEP3STADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG4.5438e-040.1854image
chr22:40927169-40931738:+STADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER3.2305e-040.1901image
chr22:40888269-40891172:+STADGSVA_HALLMARK_HEDGEHOG_SIGNALINGEER2.9344e-030.4639image
ENSG00000196236.11,XPNPEP3TGCTGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEAG6.7646e-060.3778image
chr22:40927169-40931738:+TGCTGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEER6.6919e-060.3780image
chr22:40927169-40931738:+THCAGSVA_HALLMARK_APOPTOSISEER4.7849e-070.2419image
ENSG00000196236.11,XPNPEP3THCAGSVA_HALLMARK_APOPTOSISEAG4.4155e-070.2426image
ENSG00000196236.11,XPNPEP3THYMGSVA_HALLMARK_P53_PATHWAYEAG1.5375e-020.2316image
chr22:40927169-40931738:+THYMGSVA_HALLMARK_P53_PATHWAYEER1.5375e-020.2316image
ENSG00000196236.11,XPNPEP3UCECGSVA_HALLMARK_PROTEIN_SECRETIONEAG3.9268e-060.3556image
chr22:40927169-40931738:+UCECGSVA_HALLMARK_PROTEIN_SECRETIONEER7.9116e-070.3787image
ENSG00000196236.11,XPNPEP3UCSGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG3.5563e-040.4943image
ENSG00000196236.11,XPNPEP3UVMGSVA_HALLMARK_P53_PATHWAYEAG6.8239e-040.4687image


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7. Enriched editing regions and drugs for XPNPEP3


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
ENSG00000196236.11,XPNPEP3ACCABT.888EAG3.0554e-030.3421image
chr22:40927169-40931738:+ACCABT.888EER3.0554e-030.3421image
chr22:40927169-40931738:+BLCADocetaxelEER2.0000e-03-0.1644image
ENSG00000196236.11,XPNPEP3BLCADocetaxelEAG2.0000e-03-0.1644image
ENSG00000196236.11,XPNPEP3BRCAEHT.1864EAG7.9473e-040.1027image
chr22:40927169-40931738:+BRCAEHT.1864EER9.4195e-040.1013image
ENSG00000196236.11,XPNPEP3CESCATRAEAG2.7313e-03-0.1827image
chr22:40927169-40931738:+CESCATRAEER2.6331e-03-0.1834image
chr22:40927169-40931738:+CHOLCEP.701EER2.1522e-020.3873image
ENSG00000196236.11,XPNPEP3CHOLCEP.701EAG2.1072e-020.3886image
ENSG00000196236.11,XPNPEP3COADJNJ.26854165EAG1.7642e-02-0.1571image
chr22:40927169-40931738:+COADJNJ.26854165EER2.0129e-02-0.1542image
ENSG00000196236.11,XPNPEP3DLBCCCT018159EAG2.8887e-02-0.3457image
chr22:40927169-40931738:+DLBCCCT018159EER2.8887e-02-0.3457image
ENSG00000196236.11,XPNPEP3ESCAAZD.2281EAG4.7222e-05-0.3159image
chr22:40927169-40931738:+ESCAAZD.2281EER4.3153e-05-0.3174image
chr22:40927169-40931738:+GBMBAY.61.3606EER3.5369e-040.2870image
ENSG00000196236.11,XPNPEP3GBMBAY.61.3606EAG3.4573e-040.2874image
ENSG00000196236.11,XPNPEP3HNSCBMS.708163EAG2.3351e-05-0.2044image
chr22:40927169-40931738:+HNSCBMS.708163EER2.3351e-05-0.2044image
chr22:40927169-40931738:+KICHGW843682XEER1.1867e-030.3963image
ENSG00000196236.11,XPNPEP3KICHGW843682XEAG1.1867e-030.3963image
ENSG00000196236.11,XPNPEP3KIRCCGP.60474EAG4.1903e-05-0.2124image
chr22:40927169-40931738:+KIRCCGP.60474EER4.1925e-05-0.2124image
chr22:40927169-40931738:+KIRPCI.1040EER6.6022e-05-0.2378image
ENSG00000196236.11,XPNPEP3KIRPCI.1040EAG6.6024e-05-0.2378image
chr22:40927169-40931738:+LGGDoxorubicinEER5.5091e-060.2007image
ENSG00000196236.11,XPNPEP3LGGDoxorubicinEAG5.7851e-060.2002image
ENSG00000196236.11,XPNPEP3LIHCBAY.61.3606EAG1.3271e-07-0.2790image
chr22:40927169-40931738:+LIHCBAY.61.3606EER1.3354e-07-0.2789image
chr22:40927169-40931738:+LUADFH535EER2.5045e-030.1433image
ENSG00000196236.11,XPNPEP3LUADFH535EAG2.5687e-030.1428image
chr22:40927169-40931738:+LUSCGDC.0449EER1.2438e-08-0.2604image
ENSG00000196236.11,XPNPEP3LUSCGDC.0449EAG1.3101e-08-0.2600image
ENSG00000196236.11,XPNPEP3MESOAS601245EAG9.3288e-03-0.3131image
chr22:40888269-40891172:+OVCamptothecinEER8.5713e-030.5241image
ENSG00000196236.11,XPNPEP3OVEmbelinEAG6.8447e-040.1993image
chr22:40927169-40931738:+OVEmbelinEER6.9570e-040.1990image
ENSG00000196236.11,XPNPEP3PAADAUY922EAG2.2307e-02-0.1884image
chr22:40927169-40931738:+PAADAUY922EER2.2307e-02-0.1884image
chr22:40927169-40931738:+PCPGBIBW2992EER3.4265e-030.2399image
ENSG00000196236.11,XPNPEP3PCPGBIBW2992EAG3.4265e-030.2399image
chr22:40927169-40931738:+PRADGSK269962AEER2.5837e-03-0.1375image
ENSG00000196236.11,XPNPEP3PRADGSK269962AEAG2.5272e-03-0.1378image
ENSG00000196236.11,XPNPEP3READImatinibEAG2.0008e-02-0.2534image
chr22:40927169-40931738:+READImatinibEER2.0008e-02-0.2534image
chr22:40927169-40931738:+SARCAP.24534EER1.5646e-04-0.2437image
ENSG00000196236.11,XPNPEP3SARCAP.24534EAG1.5646e-04-0.2437image
ENSG00000196236.11,XPNPEP3SKCMABT.888EAG1.3527e-03-0.1555image
chr22:40927169-40931738:+SKCMABT.888EER1.4359e-03-0.1547image
ENSG00000196236.11,XPNPEP3STADCI.1040EAG3.4493e-03-0.1551image
chr22:40927169-40931738:+STADCI.1040EER3.5359e-03-0.1546image
chr22:40927169-40931738:+TGCTDocetaxelEER1.9304e-04-0.3167image
ENSG00000196236.11,XPNPEP3TGCTDocetaxelEAG1.9024e-04-0.3170image
ENSG00000196236.11,XPNPEP3THCAMetforminEAG6.9376e-060.2166image
chr22:40927169-40931738:+THCAMetforminEER7.5624e-060.2158image
ENSG00000196236.11,XPNPEP3THYMJNK.9LEAG1.1536e-02-0.2411image
chr22:40927169-40931738:+THYMJNK.9LEER1.1536e-02-0.2411image
ENSG00000196236.11,XPNPEP3UCECBMS.536924EAG9.5431e-040.2587image
chr22:40927169-40931738:+UCECBMS.536924EER1.9042e-040.2909image
ENSG00000196236.11,XPNPEP3UCSCCT007093EAG1.4807e-030.4462image
ENSG00000196236.11,XPNPEP3UVMBexaroteneEAG3.0505e-05-0.5584image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType