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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: SDHC (ImmuneEditome ID:6391)

1. Gene summary of enriched editing regions for SDHC

check button Gene summary
Gene informationGene symbol

SDHC

Gene ID

6391

GeneSynonymsCYB560|CYBL|PGL3|QPS1|SDH3
GeneCytomap

1q23.3

GeneTypeprotein-coding
GeneDescriptionsuccinate dehydrogenase cytochrome b560 subunit, mitochondrial|cytochrome B large subunit of complex II|integral membrane protein CII-3b|large subunit of cytochrome b|succinate dehydrgenase cytochrome b|succinate dehydrogenase 3, integral membrane subunit|succinate dehydrogenase complex subunit C integral membrane protein 15kDa|succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD|succinate-ubiquinone oxidoreductase cytochrome B large subunit
GeneModificationdate20230329
UniprotIDQ99643;A0A0S2Z4B7;D6RBX6;A0A0S2Z4C9
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr1:161348525-161349361:+ENST00000342751.7ENSG00000143252.13SDHCintronicAluSx,AluSz6,A-richchr1:161348525-161349361:+.alignment
chr1:161348525-161349361:+ENST00000367975.5ENSG00000143252.13SDHCintronicAluSx,AluSz6,A-richchr1:161348525-161349361:+.alignment
chr1:161348525-161349361:+ENST00000392169.5ENSG00000143252.13SDHCintronicAluSx,AluSz6,A-richchr1:161348525-161349361:+.alignment
chr1:161348525-161349361:+ENST00000432287.5ENSG00000143252.13SDHCintronicAluSx,AluSz6,A-richchr1:161348525-161349361:+.alignment
chr1:161348525-161349361:+ENST00000470743.4ENSG00000143252.13SDHCintronicAluSx,AluSz6,A-richchr1:161348525-161349361:+.alignment
chr1:161348525-161349361:+ENST00000504963.4ENSG00000143252.13SDHCintronicAluSx,AluSz6,A-richchr1:161348525-161349361:+.alignment
chr1:161348525-161349361:+ENST00000513009.4ENSG00000143252.13SDHCintronicAluSx,AluSz6,A-richchr1:161348525-161349361:+.alignment
chr1:161354897-161355902:+ENST00000342751.7ENSG00000143252.13SDHCintronicAluSz,L1M4,AluSz6,(TCTTATT)nchr1:161354897-161355902:+.alignment
chr1:161354897-161355902:+ENST00000367975.5ENSG00000143252.13SDHCintronicAluSz,L1M4,AluSz6,(TCTTATT)nchr1:161354897-161355902:+.alignment
chr1:161354897-161355902:+ENST00000392169.5ENSG00000143252.13SDHCintronicAluSz,L1M4,AluSz6,(TCTTATT)nchr1:161354897-161355902:+.alignment
chr1:161354897-161355902:+ENST00000432287.5ENSG00000143252.13SDHCintronicAluSz,L1M4,AluSz6,(TCTTATT)nchr1:161354897-161355902:+.alignment
chr1:161354897-161355902:+ENST00000470743.4ENSG00000143252.13SDHCintronicAluSz,L1M4,AluSz6,(TCTTATT)nchr1:161354897-161355902:+.alignment
chr1:161354897-161355902:+ENST00000504963.4ENSG00000143252.13SDHCintronicAluSz,L1M4,AluSz6,(TCTTATT)nchr1:161354897-161355902:+.alignment
chr1:161354897-161355902:+ENST00000513009.4ENSG00000143252.13SDHCintronicAluSz,L1M4,AluSz6,(TCTTATT)nchr1:161354897-161355902:+.alignment
chr1:161368932-161372960:+ENST00000437833.2ENSG00000143252.13SDHCncRNA_exonicAluY,MIRb,AluYm1,L1M5,MIRc,AluSz,AluSx3,L1ME4b,AluSc,(T)n,AluJr,AluJbchr1:161368932-161372960:+.alignment
chr1:161373918-161375074:+ENST00000367975.5ENSG00000143252.13SDHCUTR3AluSx,AluSpchr1:161373918-161375074:+.alignment


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2. Tumor-specific enriched editing regions for SDHC


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chr1:161368932-161372960:+KIRCEER1.8352e-03image
ENSG00000143252.13,SDHCKIRCEAG2.8825e-03image
chr1:161368932-161372960:+KIRPEER1.4311e-02image
ENSG00000143252.13,SDHCKIRPEAG1.7242e-02image


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
chr1:161368932-161372960:+MESOEER2.3700e-023.6639e-021.2166e-04image
ENSG00000143252.13,SDHCMESOEAG2.3700e-023.6705e-021.2215e-04image

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3. Enriched editing regions and immune related genes for SDHC


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr1:161368932-161372960:+ESCAEERENSG00000247271,ZBED5-AS10.36679.6053e-032.1577e-060.4154imageNEIF4A3;ELAVL1;FBL;FUS;IGF2BP2;NOP58;UPF1NANK_cells_activatedGSVA_HALLMARK_KRAS_SIGNALING_UP

More results



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4. Enriched editing regions and immune related splicing for SDHC


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr1:161368932-161372960:+
ESCAEERA5ENSG00000125459.10chr1155747128:155747183:155746795:155746871:155746795:155746935-0.41669.5974e-035.0130e-08-0.4744imageNEIF4A3;ELAVL1;FBL;FUS;IGF2BP2;NOP58;UPF1NAT_cells_CD8GSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALING
ENSG00000143252.13,SDHC
ESCAEAGA5ENSG00000125459.10chr1155747128:155747183:155746795:155746871:155746795:155746935-0.39911.6415e-022.7536e-07-0.4453imageNACIN1;ADAR;AIFM1;BCCIP;BUD13;CELF2;CNBP;CSTF2T;DDX42;DDX54;EIF4A3;ELAVL1;FBL;FMR1;FTO;FUS;HNRNPA2B1;HNRNPK;IGF2BP2;IGF2BP3;LIN28;NOP56;NOP58;PCBP2;PRPF8;PTBP1;RANGAP1;RBM10;RBM22;SF3A3;SF3B4;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;TAF15;TARDBP;TIA1;TIAL1;U2AF1;U2AF2;UPF1;YTHDC1;YTHDF1;YWHAGNAT_cells_CD8GSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALING

More results



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5. Enriched editing regions and immune infiltration for SDHC


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chr1:161368932-161372960:+BLCAEERT_cells_CD4_memory_activated3.4664e-03-0.3809image
ENSG00000143252.13,SDHCBLCAEAGT_cells_CD4_memory_activated3.0174e-03-0.3736image
chr1:161368932-161372960:+BRCAEERT_cells_CD4_naive2.9190e-020.1053image
ENSG00000143252.13,SDHCBRCAEAGT_cells_CD4_naive2.9010e-020.1046image
chr1:161368932-161372960:+CESCEERB_cells_memory3.2750e-030.4003image
ENSG00000143252.13,SDHCCESCEAGB_cells_memory1.9496e-030.4087image
chr1:161368932-161372960:+CHOLEERT_cells_CD85.0220e-030.5760image
ENSG00000143252.13,SDHCCHOLEAGT_cells_CD84.8404e-030.5780image
ENSG00000143252.13,SDHCCOADEAGMast_cells_activated2.2667e-020.5065image
chr1:161368932-161372960:+ESCAEERDendritic_cells_activated1.9664e-02-0.2118image
ENSG00000143252.13,SDHCESCAEAGDendritic_cells_activated4.1926e-02-0.1830image
chr1:161368932-161372960:+GBMEERMacrophages_M01.8372e-020.2773image
ENSG00000143252.13,SDHCGBMEAGMacrophages_M02.3887e-020.2642image
chr1:161368932-161372960:+KIRCEERB_cells_naive2.8435e-02-0.1478image
ENSG00000143252.13,SDHCKIRCEAGB_cells_naive4.7305e-02-0.1333image
ENSG00000143252.13,SDHCLAMLEAGB_cells_naive3.5390e-030.5609image
chr1:161368932-161372960:+LGGEERNeutrophils1.7246e-030.1527image
ENSG00000143252.13,SDHCLGGEAGNeutrophils1.7161e-030.1522image
chr1:161368932-161372960:+LIHCEERT_cells_gamma_delta9.7635e-040.2838image
ENSG00000143252.13,SDHCLIHCEAGT_cells_gamma_delta4.5256e-040.2988image
chr1:161368932-161372960:+LUADEERB_cells_naive1.6549e-020.2357image
ENSG00000143252.13,SDHCLUADEAGB_cells_naive4.6693e-020.1937image
chr1:161368932-161372960:+LUSCEERT_cells_CD4_memory_activated5.9670e-030.3482image
ENSG00000143252.13,SDHCLUSCEAGT_cells_CD4_memory_activated2.7965e-030.3677image
chr1:161368932-161372960:+MESOEERT_cells_CD4_memory_resting4.0326e-02-0.4402image
ENSG00000143252.13,SDHCMESOEAGT_cells_CD4_memory_resting4.0254e-02-0.4404image
chr1:161368932-161372960:+OVEERDendritic_cells_activated9.0408e-050.2726image
chr1:161373918-161375074:+OVEERMacrophages_M04.9651e-02-0.4138image
ENSG00000143252.13,SDHCOVEAGDendritic_cells_activated5.9579e-040.2395image
chr1:161368932-161372960:+PCPGEERB_cells_memory1.4301e-020.2407image
ENSG00000143252.13,SDHCPRADEAGDendritic_cells_activated5.5497e-03-0.2796image
chr1:161368932-161372960:+SARCEERMacrophages_M09.8310e-03-0.3230image
ENSG00000143252.13,SDHCSARCEAGMacrophages_M01.0051e-02-0.3196image
chr1:161348525-161349361:+STADEERMacrophages_M21.1079e-020.4432image
chr1:161368932-161372960:+STADEERT_cells_gamma_delta7.2294e-030.1819image
ENSG00000143252.13,SDHCSTADEAGDendritic_cells_activated1.1573e-020.1666image
chr1:161368932-161372960:+TGCTEERT_cells_CD4_memory_activated3.4500e-020.2648image
chr1:161368932-161372960:+THCAEERMacrophages_M11.0352e-02-0.1649image
chr1:161373918-161375074:+THCAEERNK_cells_activated2.0777e-02-0.3690image
ENSG00000143252.13,SDHCTHCAEAGMacrophages_M17.8105e-03-0.1682image
chr1:161368932-161372960:+THYMEERT_cells_CD83.5608e-020.3564image
chr1:161368932-161372960:+UCECEERT_cells_CD84.0072e-020.3707image


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6. Enriched editing regions and immune gene sets for SDHC


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
ENSG00000143252.13,SDHCBLCAGSVA_HALLMARK_ALLOGRAFT_REJECTIONEAG1.4313e-02-0.3122image
chr1:161368932-161372960:+BLCAGSVA_HALLMARK_ALLOGRAFT_REJECTIONEER5.9628e-03-0.3599image
chr1:161368932-161372960:+BRCAGSVA_HALLMARK_MITOTIC_SPINDLEEER3.0623e-04-0.1735image
ENSG00000143252.13,SDHCBRCAGSVA_HALLMARK_MITOTIC_SPINDLEEAG1.3822e-04-0.1815image
ENSG00000143252.13,SDHCCHOLGSVA_HALLMARK_PROTEIN_SECRETIONEAG2.6266e-03-0.6090image
chr1:161368932-161372960:+CHOLGSVA_HALLMARK_PROTEIN_SECRETIONEER2.8495e-03-0.6051image
chr1:161368932-161372960:+ESCAGSVA_HALLMARK_ESTROGEN_RESPONSE_EARLYEER9.1103e-03-0.2362image
ENSG00000143252.13,SDHCESCAGSVA_HALLMARK_ESTROGEN_RESPONSE_EARLYEAG6.4382e-03-0.2435image
ENSG00000143252.13,SDHCHNSCGSVA_HALLMARK_TGF_BETA_SIGNALINGEAG1.5802e-02-0.5195image
chr1:161368932-161372960:+KIRCGSVA_HALLMARK_MYOGENESISEER1.5390e-02-0.1632image
ENSG00000143252.13,SDHCKIRCGSVA_HALLMARK_MYOGENESISEAG1.2847e-02-0.1667image
ENSG00000143252.13,SDHCLAMLGSVA_HALLMARK_PROTEIN_SECRETIONEAG4.8764e-03-0.5447image
ENSG00000143252.13,SDHCLGGGSVA_HALLMARK_ALLOGRAFT_REJECTIONEAG1.0969e-02-0.1237image
chr1:161373918-161375074:+LGGGSVA_HALLMARK_APICAL_SURFACEEER1.9048e-030.6122image
chr1:161368932-161372960:+LGGGSVA_HALLMARK_ALLOGRAFT_REJECTIONEER8.9797e-03-0.1275image
ENSG00000143252.13,SDHCLIHCGSVA_HALLMARK_ANDROGEN_RESPONSEEAG2.0207e-05-0.3592image
chr1:161368932-161372960:+LIHCGSVA_HALLMARK_ANDROGEN_RESPONSEEER5.6058e-05-0.3432image
ENSG00000143252.13,SDHCLUADGSVA_HALLMARK_HEDGEHOG_SIGNALINGEAG9.2767e-03-0.2516image
chr1:161368932-161372960:+LUADGSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALINGEER4.7706e-03-0.2760image
ENSG00000143252.13,SDHCLUSCGSVA_HALLMARK_APICAL_JUNCTIONEAG2.1684e-04-0.4465image
chr1:161368932-161372960:+LUSCGSVA_HALLMARK_APICAL_JUNCTIONEER3.3705e-04-0.4441image
chr1:161368932-161372960:+MESOGSVA_HALLMARK_TGF_BETA_SIGNALINGEER1.9648e-03-0.6228image
ENSG00000143252.13,SDHCMESOGSVA_HALLMARK_TGF_BETA_SIGNALINGEAG1.9607e-03-0.6228image
ENSG00000143252.13,SDHCOVGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG3.1587e-04-0.2509image
chr1:161373918-161375074:+OVGSVA_HALLMARK_ANDROGEN_RESPONSEEER4.6317e-020.4195image
chr1:161368932-161372960:+OVGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER1.1344e-04-0.2689image
ENSG00000143252.13,SDHCPCPGGSVA_HALLMARK_COAGULATIONEAG2.9211e-02-0.2090image
chr1:161368932-161372960:+PCPGGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER4.1745e-02-0.2010image
ENSG00000143252.13,SDHCPRADGSVA_HALLMARK_GLYCOLYSISEAG1.9876e-03-0.3102image
chr1:161368932-161372960:+SARCGSVA_HALLMARK_TGF_BETA_SIGNALINGEER2.1720e-030.3793image
ENSG00000143252.13,SDHCSARCGSVA_HALLMARK_TGF_BETA_SIGNALINGEAG8.9896e-030.3241image
ENSG00000143252.13,SDHCSKCMGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEAG7.9688e-06-0.4404image
chr1:161368932-161372960:+SKCMGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEER1.8840e-05-0.4279image
ENSG00000143252.13,SDHCSTADGSVA_HALLMARK_MITOTIC_SPINDLEEAG3.1678e-05-0.2713image
chr1:161373918-161375074:+STADGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER8.6986e-030.5700image
chr1:161348525-161349361:+STADGSVA_HALLMARK_ANGIOGENESISEER1.7249e-020.4181image
chr1:161368932-161372960:+STADGSVA_HALLMARK_MITOTIC_SPINDLEEER7.2596e-04-0.2277image
chr1:161368932-161372960:+TGCTGSVA_HALLMARK_PROTEIN_SECRETIONEER1.6125e-02-0.2997image
ENSG00000143252.13,SDHCTGCTGSVA_HALLMARK_BILE_ACID_METABOLISMEAG2.5091e-02-0.2799image
chr1:161373918-161375074:+THCAGSVA_HALLMARK_UV_RESPONSE_DNEER3.5089e-020.3384image
ENSG00000143252.13,SDHCTHYMGSVA_HALLMARK_PANCREAS_BETA_CELLSEAG2.6992e-02-0.3497image
chr1:161368932-161372960:+UCECGSVA_HALLMARK_NOTCH_SIGNALINGEER2.0961e-02-0.4129image


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7. Enriched editing regions and drugs for SDHC


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
ENSG00000143252.13,SDHCBLCAKU.55933EAG1.7747e-020.3027image
chr1:161368932-161372960:+BLCAKU.55933EER5.8756e-030.3605image
chr1:161368932-161372960:+BRCAEHT.1864EER1.7597e-02-0.1146image
ENSG00000143252.13,SDHCBRCAEHT.1864EAG1.9662e-02-0.1117image
ENSG00000143252.13,SDHCCESCElesclomolEAG2.0934e-03-0.4061image
chr1:161368932-161372960:+CESCElesclomolEER1.5927e-03-0.4270image
ENSG00000143252.13,SDHCCHOLA.770041EAG3.2308e-03-0.5989image
chr1:161368932-161372960:+CHOLA.770041EER3.1348e-03-0.6004image
ENSG00000143252.13,SDHCCOADDocetaxelEAG3.3371e-020.4772image
ENSG00000143252.13,SDHCESCAAZD.2281EAG5.4342e-04-0.3062image
chr1:161368932-161372960:+ESCAATRAEER1.7241e-03-0.2820image
ENSG00000143252.13,SDHCHNSCEpothilone.BEAG3.9206e-02-0.4530image
chr1:161368932-161372960:+KIRCFH535EER9.7068e-040.2209image
ENSG00000143252.13,SDHCKIRCFH535EAG1.3407e-030.2140image
chr1:161373918-161375074:+KIRPCamptothecinEER4.2476e-02-0.3553image
ENSG00000143252.13,SDHCLAMLAZD7762EAG7.9407e-04-0.6271image
chr1:161373918-161375074:+LGGATRAEER4.6893e-030.5680image
ENSG00000143252.13,SDHCLGGGDC0941EAG1.5741e-02-0.1175image
chr1:161368932-161372960:+LGGGDC0941EER1.6360e-02-0.1172image
ENSG00000143252.13,SDHCLIHCFH535EAG1.0533e-020.2203image
chr1:161368932-161372960:+LIHCFH535EER2.1443e-020.2001image
ENSG00000143252.13,SDHCLUADBryostatin.1EAG2.9706e-02-0.2113image
chr1:161368932-161372960:+LUADBryostatin.1EER3.1849e-02-0.2117image
chr1:161368932-161372960:+LUSCAZD6482EER1.0466e-040.4762image
ENSG00000143252.13,SDHCLUSCAZD6482EAG2.7420e-040.4400image
ENSG00000143252.13,SDHCMESOJNK.9LEAG5.4033e-03-0.5721image
chr1:161368932-161372960:+MESOJNK.9LEER5.3820e-03-0.5723image
ENSG00000143252.13,SDHCOVBexaroteneEAG4.6597e-050.2824image
chr1:161368932-161372960:+OVBexaroteneEER8.6082e-060.3081image
chr1:161368932-161372960:+PCPGFH535EER4.4234e-030.2783image
ENSG00000143252.13,SDHCPCPGCGP.60474EAG2.9891e-030.2818image
ENSG00000143252.13,SDHCPRADCytarabineEAG6.1821e-03-0.2762image
chr1:161368932-161372960:+SARCEtoposideEER3.4386e-02-0.2670image
ENSG00000143252.13,SDHCSKCMEpothilone.BEAG2.6086e-03-0.3055image
chr1:161368932-161372960:+SKCMEpothilone.BEER7.9816e-03-0.2735image
chr1:161368932-161372960:+STADEHT.1864EER9.2691e-04-0.2233image
ENSG00000143252.13,SDHCSTADFTI.277EAG1.6244e-02-0.1587image
chr1:161373918-161375074:+STADCEP.701EER7.8952e-03-0.5758image
chr1:161348525-161349361:+STADAxitinibEER2.6115e-02-0.3929image
chr1:161368932-161372960:+THCABI.D1870EER1.2961e-02-0.1599image
ENSG00000143252.13,SDHCTHCABI.D1870EAG1.6995e-02-0.1512image
chr1:161373918-161375074:+THCAAP.24534EER2.9638e-02-0.3486image
ENSG00000143252.13,SDHCUCECAZD6244EAG1.2623e-02-0.4116image
chr1:161368932-161372960:+UCECAZD6244EER1.6666e-02-0.4336image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType