CAeditome Logo

Home

Download

Statistics

Landscape

Help

Contact
Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: RPS19 (ImmuneEditome ID:6223)

1. Gene summary of enriched editing regions for RPS19

check button Gene summary
Gene informationGene symbol

RPS19

Gene ID

6223

GeneSynonymsDBA|DBA1|LOH19CR1|S19|eS19
GeneCytomap

19q13.2

GeneTypeprotein-coding
GeneDescription40S ribosomal protein S19|loss of heterozygosity on chromosome 19, region 1|loss of heterozygosity, 19, chromosomal region 1|small ribosomal subunit protein eS19
GeneModificationdate20230409
UniprotIDP39019;B0ZBD0;M0R140;A0A075B6E2;M0R2L9;M0QYF7
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr19:41863014-41863992:+ENST00000598399.1ENSG00000105372.5RPS19exonicAluJo,AluSc,MIR3,MER58Bchr19:41863014-41863992:+.alignment
chr19:41865182-41867774:+ENST00000221975.5ENSG00000105372.5RPS19intronicMIRb,AluSx1,AluY,AluYm1,MER2,AluJb,AluSx3,AluSx,AluJochr19:41865182-41867774:+.alignment
chr19:41865182-41867774:+ENST00000593863.4ENSG00000105372.5RPS19intronicMIRb,AluSx1,AluY,AluYm1,MER2,AluJb,AluSx3,AluSx,AluJochr19:41865182-41867774:+.alignment
chr19:41865182-41867774:+ENST00000598261.1ENSG00000105372.5RPS19intronicMIRb,AluSx1,AluY,AluYm1,MER2,AluJb,AluSx3,AluSx,AluJochr19:41865182-41867774:+.alignment
chr19:41865182-41867774:+ENST00000598399.1ENSG00000105372.5RPS19intronicMIRb,AluSx1,AluY,AluYm1,MER2,AluJb,AluSx3,AluSx,AluJochr19:41865182-41867774:+.alignment
chr19:41865182-41867774:+ENST00000598742.4ENSG00000105372.5RPS19intronicMIRb,AluSx1,AluY,AluYm1,MER2,AluJb,AluSx3,AluSx,AluJochr19:41865182-41867774:+.alignment
chr19:41865182-41867774:+ENST00000600467.4ENSG00000105372.5RPS19intronicMIRb,AluSx1,AluY,AluYm1,MER2,AluJb,AluSx3,AluSx,AluJochr19:41865182-41867774:+.alignment
chr19:41865182-41867774:+ENST00000601492.4ENSG00000105372.5RPS19intronicMIRb,AluSx1,AluY,AluYm1,MER2,AluJb,AluSx3,AluSx,AluJochr19:41865182-41867774:+.alignment
chr19:41869984-41872900:+ENST00000221975.5ENSG00000105372.5RPS19exonicMIR3,AluSp,MIRb,AluSxchr19:41869984-41872900:+.alignment
chr19:41869984-41872900:+ENST00000593863.4ENSG00000105372.5RPS19exonicMIR3,AluSp,MIRb,AluSxchr19:41869984-41872900:+.alignment
chr19:41869984-41872900:+ENST00000598742.4ENSG00000105372.5RPS19exonicMIR3,AluSp,MIRb,AluSxchr19:41869984-41872900:+.alignment


Top

2. Tumor-specific enriched editing regions for RPS19


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chr19:41869984-41872900:+BRCAEER8.5737e-05image
ENSG00000105372.5,RPS19BRCAEAG8.3668e-05image
chr19:41869984-41872900:+HNSCEER5.3748e-05image
ENSG00000105372.5,RPS19HNSCEAG5.4255e-05image
ENSG00000105372.5,RPS19KICHEAG6.2267e-09image
chr19:41869984-41872900:+KIRCEER1.5598e-04image
ENSG00000105372.5,RPS19KIRCEAG1.4715e-04image
chr19:41869984-41872900:+KIRPEER8.1351e-04image
ENSG00000105372.5,RPS19KIRPEAG8.3042e-04image
chr19:41869984-41872900:+STADEER1.2966e-02image
ENSG00000105372.5,RPS19STADEAG9.8798e-03image
chr19:41869984-41872900:+UCECEER3.9120e-02image
ENSG00000105372.5,RPS19UCECEAG3.8966e-02image


Top

check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
ENSG00000105372.5,RPS19HNSCCliEAG1.5501e-021.6007e-020.1094image
chr19:41869984-41872900:+HNSCCliEER1.5504e-021.6200e-020.1092image
ENSG00000105372.5,RPS19KIRCPathEAG2.9392e-026.9791e-03-0.1170image
chr19:41869984-41872900:+KIRCPathEER3.2122e-027.6505e-03-0.1156image


Top

check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
chr19:41865182-41867774:+LAMLEER4.4180e-023.3679e-031.6777e-04image
chr19:41869984-41872900:+LUSCEER4.0143e-022.4049e-025.1737e-02image
ENSG00000105372.5,RPS19LUSCEAG3.0265e-021.9553e-024.5456e-02image

Top

3. Enriched editing regions and immune related genes for RPS19


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr19:41869984-41872900:+BLCAEERENSG00000160710,ADAR0.46235.1437e-192.5127e-180.4159imageNAIFM1;AUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FBL;FTO;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;NPM1;PTBP1;RBM10;RBM22;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1;VIMADARMacrophages_M1GSVA_HALLMARK_MITOTIC_SPINDLE
chr19:41869984-41872900:+LIHCEERENSG00000076321,KLHL200.51842.6238e-201.6589e-230.4883imageNAIFM1;AUH;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FBL;FUS;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;NPM1;PTBP1;RBM10;RBM22;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1;VIMKLHL20T_cells_regulatory_(Tregs)GSVA_HALLMARK_PROTEIN_SECRETION
chr19:41869984-41872900:+LIHCEERENSG00000198146,ZNF7700.48867.0833e-183.0226e-190.4439imageNAIFM1;AUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;EIF4A3;ELAVL1;ELAVL3;EWSR1;FBL;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;NPM1;PTBP1;RBM10;RBM22;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_PROTEIN_SECRETION
chr19:41869984-41872900:+LIHCEERENSG00000135100,HNF1A0.48697.0833e-188.5041e-220.4712imageNAUH;CSTF2T;DGCR8;DKC1;ELAVL1;EWSR1;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;LIN28B;NOP58;SRSF1;SRSF7;TAF15;U2AF2;UPF1HNF1AMacrophages_M1GSVA_HALLMARK_MITOTIC_SPINDLE
chr19:41869984-41872900:+LIHCEERENSG00000171100,MTM10.48667.0833e-182.4503e-180.4335imageNAIFM1;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DKC1;EIF4A3;ELAVL1;ELAVL3;FBL;FTO;FUS;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;PTBP1;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_PROTEIN_SECRETION
chr19:41869984-41872900:+LIHCEERENSG00000198690,FAN10.48687.0833e-189.3311e-200.4496imageNAIFM1;AUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FBL;FTO;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;PTBP1;RBM10;RBM22;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1;VIMFAN1Mast_cells_restingGSVA_HALLMARK_MITOTIC_SPINDLE
chr19:41869984-41872900:+LIHCEERENSG00000168653,NDUFS5-0.48129.4510e-182.3779e-19-0.4450imageNAIFM1;AUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;FBL;FTO;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;LIN28;LIN28B;NONO;NOP56;NOP58;PTBP1;RBM10;RBM22;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1NAT_cells_CD4_memory_restingGSVA_HALLMARK_ANDROGEN_RESPONSE
chr19:41869984-41872900:+LIHCEERENSG00000087299,L2HGDH0.47901.1135e-172.8489e-170.4208imageNAUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FBL;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;NPM1;PTBP1;RBM10;RBM22;SRSF1;TAF15;TARDBP;TROVE2;U2AF2;UPF1NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr19:41869984-41872900:+LIHCEERENSG00000179967,PPP1R14BP3-0.47562.1907e-171.3991e-16-0.4124imageNNNAMacrophages_M0GSVA_HALLMARK_BILE_ACID_METABOLISM
chr19:41869984-41872900:+LIHCEERENSG00000166337,TAF10-0.47683.2955e-179.5931e-21-0.4603imageNAIFM1;AUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;EIF4A3;FBL;FTO;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;NPM1;PTBP1;RBM10;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1;VIMNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_UV_RESPONSE_DN
chr19:41869984-41872900:+BLCAEERENSG00000160710,ADAR0.46235.1437e-192.5127e-180.4159imageNAIFM1;AUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FBL;FTO;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;NPM1;PTBP1;RBM10;RBM22;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1;VIMADARMacrophages_M1GSVA_HALLMARK_MITOTIC_SPINDLE
chr19:41869984-41872900:+LIHCEERENSG00000076321,KLHL200.51842.6238e-201.6589e-230.4883imageNAIFM1;AUH;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FBL;FUS;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;NPM1;PTBP1;RBM10;RBM22;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1;VIMKLHL20T_cells_regulatory_(Tregs)GSVA_HALLMARK_PROTEIN_SECRETION
chr19:41869984-41872900:+LIHCEERENSG00000198146,ZNF7700.48867.0833e-183.0226e-190.4439imageNAIFM1;AUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;EIF4A3;ELAVL1;ELAVL3;EWSR1;FBL;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;NPM1;PTBP1;RBM10;RBM22;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_PROTEIN_SECRETION
chr19:41869984-41872900:+LIHCEERENSG00000135100,HNF1A0.48697.0833e-188.5041e-220.4712imageNAUH;CSTF2T;DGCR8;DKC1;ELAVL1;EWSR1;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;LIN28B;NOP58;SRSF1;SRSF7;TAF15;U2AF2;UPF1HNF1AMacrophages_M1GSVA_HALLMARK_MITOTIC_SPINDLE
chr19:41869984-41872900:+LIHCEERENSG00000171100,MTM10.48667.0833e-182.4503e-180.4335imageNAIFM1;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DKC1;EIF4A3;ELAVL1;ELAVL3;FBL;FTO;FUS;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;PTBP1;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_PROTEIN_SECRETION
chr19:41869984-41872900:+LIHCEERENSG00000198690,FAN10.48687.0833e-189.3311e-200.4496imageNAIFM1;AUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FBL;FTO;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;PTBP1;RBM10;RBM22;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1;VIMFAN1Mast_cells_restingGSVA_HALLMARK_MITOTIC_SPINDLE
chr19:41869984-41872900:+LIHCEERENSG00000168653,NDUFS5-0.48129.4510e-182.3779e-19-0.4450imageNAIFM1;AUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;FBL;FTO;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;LIN28;LIN28B;NONO;NOP56;NOP58;PTBP1;RBM10;RBM22;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1NAT_cells_CD4_memory_restingGSVA_HALLMARK_ANDROGEN_RESPONSE
chr19:41869984-41872900:+LIHCEERENSG00000087299,L2HGDH0.47901.1135e-172.8489e-170.4208imageNAUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FBL;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;NPM1;PTBP1;RBM10;RBM22;SRSF1;TAF15;TARDBP;TROVE2;U2AF2;UPF1NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr19:41869984-41872900:+LIHCEERENSG00000179967,PPP1R14BP3-0.47562.1907e-171.3991e-16-0.4124imageNNNAMacrophages_M0GSVA_HALLMARK_BILE_ACID_METABOLISM
chr19:41869984-41872900:+LIHCEERENSG00000166337,TAF10-0.47683.2955e-179.5931e-21-0.4603imageNAIFM1;AUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;EIF4A3;FBL;FTO;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;NPM1;PTBP1;RBM10;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1;VIMNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_UV_RESPONSE_DN
chr19:41869984-41872900:+BLCAEERENSG00000160710,ADAR0.46235.1437e-192.5127e-180.4159imageNAIFM1;AUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FBL;FTO;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;NPM1;PTBP1;RBM10;RBM22;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1;VIMADARMacrophages_M1GSVA_HALLMARK_MITOTIC_SPINDLE
chr19:41869984-41872900:+LIHCEERENSG00000076321,KLHL200.51842.6238e-201.6589e-230.4883imageNAIFM1;AUH;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FBL;FUS;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;NPM1;PTBP1;RBM10;RBM22;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1;VIMKLHL20T_cells_regulatory_(Tregs)GSVA_HALLMARK_PROTEIN_SECRETION
chr19:41869984-41872900:+LIHCEERENSG00000198146,ZNF7700.48867.0833e-183.0226e-190.4439imageNAIFM1;AUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;EIF4A3;ELAVL1;ELAVL3;EWSR1;FBL;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;NPM1;PTBP1;RBM10;RBM22;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_PROTEIN_SECRETION
chr19:41869984-41872900:+LIHCEERENSG00000135100,HNF1A0.48697.0833e-188.5041e-220.4712imageNAUH;CSTF2T;DGCR8;DKC1;ELAVL1;EWSR1;FBL;FUS;HNRNPA1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;LIN28B;NOP58;SRSF1;SRSF7;TAF15;U2AF2;UPF1HNF1AMacrophages_M1GSVA_HALLMARK_MITOTIC_SPINDLE
chr19:41869984-41872900:+LIHCEERENSG00000171100,MTM10.48667.0833e-182.4503e-180.4335imageNAIFM1;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DKC1;EIF4A3;ELAVL1;ELAVL3;FBL;FTO;FUS;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;PTBP1;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_PROTEIN_SECRETION
chr19:41869984-41872900:+LIHCEERENSG00000198690,FAN10.48687.0833e-189.3311e-200.4496imageNAIFM1;AUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FBL;FTO;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;PTBP1;RBM10;RBM22;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1;VIMFAN1Mast_cells_restingGSVA_HALLMARK_MITOTIC_SPINDLE
chr19:41869984-41872900:+LIHCEERENSG00000168653,NDUFS5-0.48129.4510e-182.3779e-19-0.4450imageNAIFM1;AUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;FBL;FTO;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;LIN28;LIN28B;NONO;NOP56;NOP58;PTBP1;RBM10;RBM22;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1NAT_cells_CD4_memory_restingGSVA_HALLMARK_ANDROGEN_RESPONSE
chr19:41869984-41872900:+LIHCEERENSG00000087299,L2HGDH0.47901.1135e-172.8489e-170.4208imageNAUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FBL;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHDRBS3;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;NPM1;PTBP1;RBM10;RBM22;SRSF1;TAF15;TARDBP;TROVE2;U2AF2;UPF1NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr19:41869984-41872900:+LIHCEERENSG00000179967,PPP1R14BP3-0.47562.1907e-171.3991e-16-0.4124imageNNNAMacrophages_M0GSVA_HALLMARK_BILE_ACID_METABOLISM
chr19:41869984-41872900:+LIHCEERENSG00000166337,TAF10-0.47683.2955e-179.5931e-21-0.4603imageNAIFM1;AUH;CPSF6;CSTF2T;DDX3X;DDX54;DGCR8;EIF4A3;FBL;FTO;FUS;GNL3;HNRNPA1;HNRNPA2B1;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;KHDRBS2;KHSRP;LIN28;LIN28B;NONO;NOP56;NOP58;NPM1;PTBP1;RBM10;SRSF1;SRSF7;TAF15;TARDBP;TROVE2;U2AF2;UPF1;VIMNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_UV_RESPONSE_DN

More results



Top

4. Enriched editing regions and immune related splicing for RPS19


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000105372.5,RPS19
BLCAEAGMEXENSG00000147403.12chrX154399486:154399594:154399802:154399917:154400497:154400626:154400701:1544009170.41064.5480e-135.1687e-170.4007imageNACIN1;AIFM1;ALYREF;AUH;BCCIP;BUD13;CBX7;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RBM6;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NANK_cells_activatedGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000105372.5,RPS19
BLCAEAGMEXENSG00000147403.12chrX154399486:154399594:154399802:154399925:154400497:154400626:154400701:1544009170.41064.5480e-135.1687e-170.4007imageNACIN1;AIFM1;ALYREF;AUH;BCCIP;BUD13;CBX7;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RBM6;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NANK_cells_activatedGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000105372.5,RPS19
BLCAEAGMEXENSG00000147403.12chrX154399486:154399594:154399802:154399945:154400497:154400626:154400701:1544008110.41064.5480e-135.1698e-170.4007imageNACIN1;AIFM1;ALYREF;AUH;BCCIP;BUD13;CBX7;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RBM6;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NANK_cells_activatedGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000105372.5,RPS19
BLCAEAGMEXENSG00000147403.12chrX154399486:154399594:154399802:154400358:154400497:154400626:154400701:1544009130.41064.5480e-135.1687e-170.4007imageNACIN1;AIFM1;ALYREF;AUH;BCCIP;BUD13;CBX7;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RBM6;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NANK_cells_activatedGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000105372.5,RPS19
BLCAEAGMEXENSG00000147403.12chrX154399486:154399594:154399802:154399917:154400557:154400626:154400701:1544009170.41054.5480e-135.1622e-170.4007imageNACIN1;AIFM1;ALYREF;AUH;BCCIP;BUD13;CBX7;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RBM6;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NANK_cells_activatedGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000105372.5,RPS19
BLCAEAGMEXENSG00000147403.12chrX154399486:154399594:154399802:154399917:154400563:154400626:154400701:1544009170.41054.5480e-135.1622e-170.4007imageNACIN1;AIFM1;ALYREF;AUH;BCCIP;BUD13;CBX7;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RBM6;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NANK_cells_activatedGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000105372.5,RPS19
BLCAEAGMEXENSG00000147403.12chrX154399486:154399594:154399802:154399925:154400474:154400626:154400701:1544009170.41054.5480e-135.1622e-170.4007imageNACIN1;AIFM1;ALYREF;AUH;BCCIP;BUD13;CBX7;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RBM6;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NANK_cells_activatedGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000105372.5,RPS19
BLCAEAGMEXENSG00000147403.12chrX154399486:154399594:154399802:154399925:154400557:154400626:154400701:1544009170.41054.5480e-135.1622e-170.4007imageNACIN1;AIFM1;ALYREF;AUH;BCCIP;BUD13;CBX7;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RBM6;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NANK_cells_activatedGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000105372.5,RPS19
BLCAEAGMEXENSG00000147403.12chrX154399486:154399594:154399802:154399925:154400563:154400626:154400701:1544009170.41054.5480e-135.1622e-170.4007imageNACIN1;AIFM1;ALYREF;AUH;BCCIP;BUD13;CBX7;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RBM6;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NANK_cells_activatedGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000105372.5,RPS19
BLCAEAGMEXENSG00000147403.12chrX154399486:154399594:154399802:154399945:154400474:154400626:154400701:1544008110.41054.5480e-135.1633e-170.4007imageNACIN1;AIFM1;ALYREF;AUH;BCCIP;BUD13;CBX7;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RBM6;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NANK_cells_activatedGSVA_HALLMARK_MITOTIC_SPINDLE

More results



Top

5. Enriched editing regions and immune infiltration for RPS19


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chr19:41869984-41872900:+BLCAEERMacrophages_M11.1120e-070.2603image
ENSG00000105372.5,RPS19BLCAEAGMacrophages_M11.1000e-070.2604image
chr19:41869984-41872900:+BRCAEERT_cells_CD4_memory_resting1.9933e-090.1816image
ENSG00000105372.5,RPS19BRCAEAGT_cells_CD4_memory_resting2.3599e-090.1808image
chr19:41869984-41872900:+CESCEERNK_cells_resting3.3129e-030.1685image
ENSG00000105372.5,RPS19CESCEAGNK_cells_resting3.3168e-030.1685image
chr19:41869984-41872900:+COADEERMacrophages_M11.2784e-020.1530image
ENSG00000105372.5,RPS19COADEAGDendritic_cells_activated9.1970e-040.2009image
ENSG00000105372.5,RPS19DLBCEAGMacrophages_M15.4406e-050.5485image
chr19:41869984-41872900:+ESCAEERB_cells_naive1.6316e-02-0.1891image
ENSG00000105372.5,RPS19ESCAEAGB_cells_naive2.8491e-03-0.2337image
chr19:41869984-41872900:+GBMEERMacrophages_M01.2890e-08-0.4225image
ENSG00000105372.5,RPS19GBMEAGMacrophages_M01.2890e-08-0.4225image
chr19:41869984-41872900:+HNSCEERT_cells_CD4_memory_resting4.6618e-040.1564image
ENSG00000105372.5,RPS19HNSCEAGT_cells_CD4_memory_resting4.4845e-040.1569image
ENSG00000105372.5,RPS19KICHEAGT_cells_follicular_helper7.6156e-040.4133image
chr19:41869984-41872900:+KIRCEERMacrophages_M27.5977e-100.3078image
ENSG00000105372.5,RPS19KIRCEAGMacrophages_M27.5347e-100.3078image
chr19:41869984-41872900:+KIRPEERMast_cells_activated1.4391e-020.1443image
ENSG00000105372.5,RPS19KIRPEAGMast_cells_activated1.4479e-020.1442image
chr19:41869984-41872900:+LAMLEERMacrophages_M02.9766e-030.2476image
ENSG00000105372.5,RPS19LAMLEAGMacrophages_M03.7216e-030.2395image
ENSG00000105372.5,RPS19LGGEAGMacrophages_M11.9240e-040.1617image
chr19:41869984-41872900:+LIHCEERT_cells_regulatory_(Tregs)2.2195e-06-0.2435image
ENSG00000105372.5,RPS19LIHCEAGT_cells_regulatory_(Tregs)2.0915e-06-0.2441image
chr19:41869984-41872900:+LUADEERT_cells_regulatory_(Tregs)7.7422e-06-0.1985image
ENSG00000105372.5,RPS19LUADEAGT_cells_regulatory_(Tregs)8.3805e-06-0.1978image
chr19:41869984-41872900:+LUSCEERT_cells_CD4_memory_activated1.6957e-050.1914image
ENSG00000105372.5,RPS19LUSCEAGT_cells_CD4_memory_activated1.3906e-050.1934image
chr19:41869984-41872900:+MESOEERDendritic_cells_activated1.3695e-02-0.2713image
ENSG00000105372.5,RPS19MESOEAGDendritic_cells_activated1.3695e-02-0.2713image
chr19:41865182-41867774:+OVEERT_cells_CD4_memory_resting1.0375e-03-0.4098image
chr19:41869984-41872900:+OVEERMacrophages_M11.0356e-020.1498image
ENSG00000105372.5,RPS19OVEAGMacrophages_M19.7493e-030.1510image
chr19:41869984-41872900:+PCPGEERNeutrophils2.0408e-020.1742image
ENSG00000105372.5,RPS19PCPGEAGNeutrophils2.0408e-020.1742image
chr19:41869984-41872900:+PRADEERT_cells_CD4_memory_resting5.0558e-040.1556image
ENSG00000105372.5,RPS19PRADEAGDendritic_cells_resting7.4086e-040.1509image
chr19:41869984-41872900:+SARCEERMacrophages_M14.2171e-030.1783image
ENSG00000105372.5,RPS19SARCEAGMacrophages_M14.1843e-030.1784image
chr19:41869984-41872900:+SKCMEERT_cells_CD88.5663e-050.1804image
ENSG00000105372.5,RPS19SKCMEAGT_cells_CD88.4836e-050.1805image
chr19:41863014-41863992:+STADEERB_cells_naive1.1971e-030.4726image
chr19:41865182-41867774:+STADEERNK_cells_activated1.7983e-020.1990image
chr19:41869984-41872900:+STADEERMast_cells_activated3.9612e-02-0.1075image
ENSG00000105372.5,RPS19STADEAGMacrophages_M23.8297e-020.1082image
chr19:41869984-41872900:+TGCTEERB_cells_naive5.9248e-070.3872image
ENSG00000105372.5,RPS19TGCTEAGB_cells_naive6.7061e-070.3855image
chr19:41869984-41872900:+THCAEERT_cells_regulatory_(Tregs)1.0393e-04-0.1720image
ENSG00000105372.5,RPS19THCAEAGT_cells_regulatory_(Tregs)1.0699e-04-0.1717image
chr19:41869984-41872900:+THYMEERT_cells_regulatory_(Tregs)3.2234e-07-0.4498image
ENSG00000105372.5,RPS19THYMEAGT_cells_regulatory_(Tregs)3.0915e-07-0.4504image
chr19:41869984-41872900:+UCECEERT_cells_CD83.5865e-04-0.2683image
ENSG00000105372.5,RPS19UCECEAGT_cells_CD83.6598e-04-0.2679image
chr19:41869984-41872900:+UVMEERT_cells_regulatory_(Tregs)2.6673e-020.2478image
ENSG00000105372.5,RPS19UVMEAGT_cells_regulatory_(Tregs)2.6606e-020.2479image


Top

6. Enriched editing regions and immune gene sets for RPS19


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot
chr19:41869984-41872900:+BLCAEER3.2624e-02image3.7002e-040.1763image
ENSG00000105372.5,RPS19BLCAEAG3.3028e-02image3.9605e-040.1754image
chr19:41869984-41872900:+HNSCEER9.4560e-04image3.3699e-060.2067image
ENSG00000105372.5,RPS19HNSCEAG9.3406e-04image3.2201e-060.2071image
chr19:41869984-41872900:+LUSCEER1.6000e-03image1.4165e-030.1426image
ENSG00000105372.5,RPS19LUSCEAG1.7464e-03image1.3129e-030.1436image


Top

check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot
ENSG00000105372.5,RPS19BLCAEAG1.7022e-050.21226.2158e-060.22271.4561e-040.18792.8409e-050.2066image
chr19:41869984-41872900:+BLCAEER1.6895e-050.21237.3746e-060.22091.5989e-040.18682.4654e-050.2082image
ENSG00000105372.5,RPS19LGGEAG1.8180e-02-0.10298.0669e-05-0.17091.7759e-02-0.10324.2544e-020.0884image
ENSG00000105372.5,RPS19UCECEAG1.3199e-050.32461.6146e-040.28304.1020e-060.34217.4897e-040.2539image
chr19:41869984-41872900:+UCECEER1.2019e-050.32601.4745e-040.28463.8130e-060.34317.3988e-040.2542image


Top

check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
ENSG00000105372.5,RPS19ACCGSVA_HALLMARK_ADIPOGENESISEAG1.6034e-020.2849image
chr19:41869984-41872900:+ACCGSVA_HALLMARK_ADIPOGENESISEER1.6144e-020.2846image
ENSG00000105372.5,RPS19BLCAGSVA_HALLMARK_MITOTIC_SPINDLEEAG3.9677e-140.3644image
chr19:41869984-41872900:+BLCAGSVA_HALLMARK_MITOTIC_SPINDLEEER3.7327e-140.3647image
ENSG00000105372.5,RPS19BRCAGSVA_HALLMARK_UV_RESPONSE_DNEAG4.3120e-140.2276image
chr19:41869984-41872900:+BRCAGSVA_HALLMARK_UV_RESPONSE_DNEER5.6475e-140.2265image
ENSG00000105372.5,RPS19CESCGSVA_HALLMARK_PROTEIN_SECRETIONEAG1.4827e-140.4232image
chr19:41869984-41872900:+CESCGSVA_HALLMARK_PROTEIN_SECRETIONEER1.4306e-140.4235image
chr19:41869984-41872900:+CHOLGSVA_HALLMARK_PROTEIN_SECRETIONEER2.8962e-030.4887image
ENSG00000105372.5,RPS19CHOLGSVA_HALLMARK_PROTEIN_SECRETIONEAG2.8403e-030.4895image
chr19:41869984-41872900:+COADGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER6.2778e-050.2437image
ENSG00000105372.5,RPS19COADGSVA_HALLMARK_PEROXISOMEEAG3.2097e-03-0.1791image
ENSG00000105372.5,RPS19DLBCGSVA_HALLMARK_MITOTIC_SPINDLEEAG1.1944e-020.3601image
chr19:41863014-41863992:+ESCAGSVA_HALLMARK_UNFOLDED_PROTEIN_RESPONSEEER8.6527e-03-0.4371image
chr19:41869984-41872900:+ESCAGSVA_HALLMARK_HEME_METABOLISMEER9.9545e-040.2571image
ENSG00000105372.5,RPS19ESCAGSVA_HALLMARK_HEME_METABOLISMEAG2.3734e-040.2858image
chr19:41865182-41867774:+ESCAGSVA_HALLMARK_MYOGENESISEER9.8217e-060.4429image
chr19:41869984-41872900:+GBMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER2.4886e-150.5627image
ENSG00000105372.5,RPS19GBMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG2.4886e-150.5627image
chr19:41869984-41872900:+HNSCGSVA_HALLMARK_UV_RESPONSE_DNEER2.0376e-100.2802image
ENSG00000105372.5,RPS19HNSCGSVA_HALLMARK_UV_RESPONSE_DNEAG1.9061e-100.2806image
ENSG00000105372.5,RPS19KICHGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEAG1.3777e-020.3089image
chr19:41869984-41872900:+KIRCGSVA_HALLMARK_PROTEIN_SECRETIONEER2.2188e-070.2609image
ENSG00000105372.5,RPS19KIRCGSVA_HALLMARK_PROTEIN_SECRETIONEAG1.9617e-070.2620image
chr19:41869984-41872900:+KIRPGSVA_HALLMARK_PROTEIN_SECRETIONEER1.1278e-090.3496image
ENSG00000105372.5,RPS19KIRPGSVA_HALLMARK_PROTEIN_SECRETIONEAG1.2396e-090.3488image
chr19:41869984-41872900:+LAMLGSVA_HALLMARK_MYC_TARGETS_V2EER1.7428e-07-0.4216image
chr19:41865182-41867774:+LAMLGSVA_HALLMARK_MYC_TARGETS_V2EER8.3012e-03-0.2862image
ENSG00000105372.5,RPS19LAMLGSVA_HALLMARK_MYC_TARGETS_V2EAG1.3419e-06-0.3889image
ENSG00000105372.5,RPS19LGGGSVA_HALLMARK_MYC_TARGETS_V1EAG2.6911e-12-0.2984image
ENSG00000105372.5,RPS19LIHCGSVA_HALLMARK_HEME_METABOLISMEAG1.2097e-120.3587image
chr19:41869984-41872900:+LIHCGSVA_HALLMARK_HEME_METABOLISMEER1.2208e-120.3586image
chr19:41869984-41872900:+LUADGSVA_HALLMARK_PROTEIN_SECRETIONEER1.1330e-060.2156image
ENSG00000105372.5,RPS19LUADGSVA_HALLMARK_PROTEIN_SECRETIONEAG1.1403e-060.2156image
chr19:41869984-41872900:+LUSCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER3.3175e-100.2767image
ENSG00000105372.5,RPS19LUSCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG2.2131e-100.2794image
ENSG00000105372.5,RPS19MESOGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG5.3196e-03-0.3051image
chr19:41869984-41872900:+MESOGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER5.3196e-03-0.3051image
chr19:41865182-41867774:+OVGSVA_HALLMARK_UV_RESPONSE_DNEER4.3817e-03-0.3600image
ENSG00000105372.5,RPS19OVGSVA_HALLMARK_PROTEIN_SECRETIONEAG5.7822e-120.3886image
chr19:41869984-41872900:+OVGSVA_HALLMARK_PROTEIN_SECRETIONEER7.5959e-120.3866image
chr19:41869984-41872900:+PAADGSVA_HALLMARK_UV_RESPONSE_DNEER1.1405e-020.1892image
ENSG00000105372.5,RPS19PAADGSVA_HALLMARK_UV_RESPONSE_DNEAG1.1358e-020.1894image
ENSG00000105372.5,RPS19PCPGGSVA_HALLMARK_PROTEIN_SECRETIONEAG4.2670e-140.5280image
chr19:41869984-41872900:+PCPGGSVA_HALLMARK_PROTEIN_SECRETIONEER4.2670e-140.5280image
chr19:41869984-41872900:+PRADGSVA_HALLMARK_MITOTIC_SPINDLEEER6.4866e-170.3632image
ENSG00000105372.5,RPS19PRADGSVA_HALLMARK_PROTEIN_SECRETIONEAG1.2092e-170.3708image
chr19:41869984-41872900:+READGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER8.6090e-060.4389image
ENSG00000105372.5,RPS19READGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG8.2938e-060.4396image
ENSG00000105372.5,RPS19SARCGSVA_HALLMARK_MITOTIC_SPINDLEEAG2.9686e-100.3807image
chr19:41869984-41872900:+SARCGSVA_HALLMARK_MITOTIC_SPINDLEEER2.9610e-100.3807image
chr19:41869984-41872900:+SKCMGSVA_HALLMARK_HEME_METABOLISMEER9.1697e-070.2244image
ENSG00000105372.5,RPS19SKCMGSVA_HALLMARK_HEME_METABOLISMEAG8.4812e-070.2250image
chr19:41863014-41863992:+STADGSVA_HALLMARK_MYOGENESISEER4.5418e-020.3032image
ENSG00000105372.5,RPS19STADGSVA_HALLMARK_IL2_STAT5_SIGNALINGEAG2.2938e-090.3055image
chr19:41869984-41872900:+STADGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER4.5567e-090.3000image
ENSG00000105372.5,RPS19TGCTGSVA_HALLMARK_MITOTIC_SPINDLEEAG2.0065e-070.4018image
chr19:41869984-41872900:+TGCTGSVA_HALLMARK_MITOTIC_SPINDLEEER1.9040e-070.4025image
chr19:41869984-41872900:+THCAGSVA_HALLMARK_HEME_METABOLISMEER4.0160e-230.4215image
ENSG00000105372.5,RPS19THCAGSVA_HALLMARK_HEME_METABOLISMEAG3.8201e-230.4217image
chr19:41869984-41872900:+THYMGSVA_HALLMARK_PROTEIN_SECRETIONEER1.1550e-140.6349image
ENSG00000105372.5,RPS19THYMGSVA_HALLMARK_PROTEIN_SECRETIONEAG1.0421e-140.6357image
chr19:41869984-41872900:+UCECGSVA_HALLMARK_MITOTIC_SPINDLEEER7.9068e-140.5284image
ENSG00000105372.5,RPS19UCECGSVA_HALLMARK_MITOTIC_SPINDLEEAG8.4838e-140.5278image
ENSG00000105372.5,RPS19UCSGSVA_HALLMARK_MYOGENESISEAG7.1319e-05-0.5053image
chr19:41869984-41872900:+UCSGSVA_HALLMARK_MYOGENESISEER7.1494e-05-0.5052image


Top

7. Enriched editing regions and drugs for RPS19


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
chr19:41869984-41872900:+ACCCI.1040EER1.6010e-02-0.2850image
ENSG00000105372.5,RPS19ACCCI.1040EAG1.5974e-02-0.2851image
ENSG00000105372.5,RPS19BLCAEmbelinEAG4.9513e-09-0.2858image
chr19:41869984-41872900:+BLCAEmbelinEER7.0105e-09-0.2831image
ENSG00000105372.5,RPS19BRCAAZD6482EAG1.9527e-20-0.2777image
chr19:41869984-41872900:+BRCAAZD6482EER1.9276e-20-0.2778image
ENSG00000105372.5,RPS19CESCAZD6482EAG2.5747e-09-0.3342image
chr19:41869984-41872900:+CESCAZD6482EER2.6757e-09-0.3339image
chr19:41869984-41872900:+CHOLAZD6482EER1.9073e-03-0.5064image
ENSG00000105372.5,RPS19CHOLAZD6482EAG1.9066e-03-0.5065image
chr19:41869984-41872900:+COADCI.1040EER8.5013e-03-0.1617image
ENSG00000105372.5,RPS19COADKIN001.135EAG1.2623e-02-0.1519image
ENSG00000105372.5,RPS19DLBCATRAEAG1.6607e-04-0.5174image
chr19:41865182-41867774:+ESCACGP.082996EER1.1450e-03-0.3338image
chr19:41869984-41872900:+ESCABMS.536924EER1.4767e-020.1918image
chr19:41863014-41863992:+ESCACyclopamineEER1.1716e-03-0.5260image
ENSG00000105372.5,RPS19ESCAAICAREAG2.2910e-03-0.2387image
chr19:41869984-41872900:+GBMBIBW2992EER1.8775e-09-0.4439image
ENSG00000105372.5,RPS19GBMBIBW2992EAG1.8775e-09-0.4439image
chr19:41869984-41872900:+HNSCAZD6482EER8.3616e-11-0.2859image
ENSG00000105372.5,RPS19HNSCAZD6482EAG7.4366e-11-0.2866image
ENSG00000105372.5,RPS19KICHBMS.754807EAG3.9686e-03-0.3580image
chr19:41869984-41872900:+KIRCGW843682XEER6.9070e-110.3252image
ENSG00000105372.5,RPS19KIRCGW843682XEAG6.0353e-110.3262image
ENSG00000105372.5,RPS19KIRPEmbelinEAG6.0672e-11-0.3737image
chr19:41869984-41872900:+KIRPEmbelinEER6.7977e-11-0.3728image
chr19:41869984-41872900:+LAMLBMS.509744EER6.0030e-060.3696image
chr19:41865182-41867774:+LAMLDMOGEER1.2925e-02-0.2702image
ENSG00000105372.5,RPS19LAMLBMS.509744EAG5.5675e-050.3282image
ENSG00000105372.5,RPS19LGGGemcitabineEAG6.9389e-180.3633image
ENSG00000105372.5,RPS19LIHCBortezomibEAG9.7632e-130.3610image
chr19:41869984-41872900:+LIHCBortezomibEER1.0250e-120.3607image
chr19:41869984-41872900:+LUADBI.D1870EER1.9705e-030.1381image
ENSG00000105372.5,RPS19LUADCCT007093EAG2.0475e-03-0.1376image
chr19:41869984-41872900:+LUSCAZD.2281EER7.3274e-06-0.1996image
ENSG00000105372.5,RPS19LUSCAZD.2281EAG6.2244e-06-0.2011image
ENSG00000105372.5,RPS19MESOBAY.61.3606EAG3.2125e-05-0.4421image
chr19:41869984-41872900:+MESOBAY.61.3606EER3.2125e-05-0.4421image
chr19:41865182-41867774:+OVAZD.0530EER2.4145e-030.3815image
chr19:41869984-41872900:+OVDMOGEER4.3488e-09-0.3350image
ENSG00000105372.5,RPS19OVDMOGEAG5.4989e-09-0.3329image
ENSG00000105372.5,RPS19PAADEmbelinEAG3.3894e-03-0.2185image
chr19:41869984-41872900:+PAADEmbelinEER3.3843e-03-0.2185image
ENSG00000105372.5,RPS19PCPGBMS.536924EAG1.7209e-060.3515image
chr19:41869984-41872900:+PCPGBMS.536924EER1.7209e-060.3515image
chr19:41869984-41872900:+PRADBMS.536924EER6.1456e-110.2890image
ENSG00000105372.5,RPS19PRADBMS.536924EAG6.3637e-100.2735image
chr19:41869984-41872900:+READJNK.9LEER4.2083e-05-0.4072image
ENSG00000105372.5,RPS19READJNK.9LEAG4.1951e-05-0.4073image
chr19:41869984-41872900:+SARCBMS.509744EER2.7169e-110.4007image
ENSG00000105372.5,RPS19SARCBMS.509744EAG2.4934e-110.4014image
ENSG00000105372.5,RPS19SKCMDocetaxelEAG5.2560e-060.2085image
chr19:41869984-41872900:+SKCMDocetaxelEER4.5639e-060.2099image
chr19:41863014-41863992:+STADAZD6482EER9.6009e-03-0.3863image
chr19:41865182-41867774:+STADAZD8055EER2.7045e-020.1862image
ENSG00000105372.5,RPS19STADAZD7762EAG1.1704e-03-0.1688image
chr19:41869984-41872900:+STADAZD7762EER8.8956e-04-0.1728image
ENSG00000105372.5,RPS19TGCTBAY.61.3606EAG1.0171e-05-0.3452image
chr19:41869984-41872900:+TGCTBAY.61.3606EER1.0266e-05-0.3451image
chr19:41869984-41872900:+THCAEmbelinEER4.4270e-23-0.4211image
ENSG00000105372.5,RPS19THCAEmbelinEAG4.3288e-23-0.4212image
chr19:41869984-41872900:+THYMGW843682XEER1.0808e-170.6856image
ENSG00000105372.5,RPS19THYMGW843682XEAG9.9678e-180.6861image
chr19:41869984-41872900:+UCECBMS.536924EER4.5568e-120.4947image
ENSG00000105372.5,RPS19UCECBMS.536924EAG4.6593e-120.4946image
ENSG00000105372.5,RPS19UCSEHT.1864EAG3.5416e-040.4606image
chr19:41869984-41872900:+UCSEHT.1864EER3.5794e-040.4603image
chr19:41869984-41872900:+UVMCCT018159EER2.9547e-020.2435image
ENSG00000105372.5,RPS19UVMCCT018159EAG2.8944e-020.2443image


Top

check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType
chr19:41865182-41867774:+ENST00000593863.4P39019DB11638ArtenimolSmallMoleculeDrug
chr19:41865182-41867774:+ENST00000598742.4P39019DB11638ArtenimolSmallMoleculeDrug
chr19:41869984-41872900:+ENST00000593863.4P39019DB11638ArtenimolSmallMoleculeDrug
chr19:41869984-41872900:+ENST00000598742.4P39019DB11638ArtenimolSmallMoleculeDrug