CAeditome Logo

Home

Download

Statistics

Landscape

Help

Contact
Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: RPL37 (ImmuneEditome ID:6167)

1. Gene summary of enriched editing regions for RPL37

check button Gene summary
Gene informationGene symbol

RPL37

Gene ID

6167

GeneSynonymsL37|eL37
GeneCytomap

5p13.1

GeneTypeprotein-coding
GeneDescription60S ribosomal protein L37|60S ribosomal protein L37a|G1.16|large ribosomal subunit protein eL37
GeneModificationdate20230329
UniprotIDP61927;D6R9X9;D6RG19
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr5:40825778-40826975:-ENST00000274242.8ENSG00000145592.12RPL37UTR3AluSx,AluJb,LTR78chr5:40825778-40826975:-.alignment
chr5:40829752-40831277:-ENST00000511787.1ENSG00000145592.12RPL37ncRNA_intronicAluSp,AluSx3,AluJb,AluScchr5:40829752-40831277:-.alignment


Top

2. Tumor-specific enriched editing regions for RPL37


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chr5:40825778-40826975:-BRCAEER2.6811e-08image
chr5:40829752-40831277:-BRCAEER4.6449e-02image
ENSG00000145592.12,RPL37BRCAEAG3.8268e-02image
ENSG00000145592.12,RPL37KIRCEAG6.4622e-03image
chr5:40829752-40831277:-KIRPEER1.1864e-02image
ENSG00000145592.12,RPL37KIRPEAG4.1741e-04image
ENSG00000145592.12,RPL37LIHCEAG9.3070e-03image
ENSG00000145592.12,RPL37LUADEAG3.4689e-03image
chr5:40829752-40831277:-LUSCEER7.2313e-05image
ENSG00000145592.12,RPL37THCAEAG1.0033e-09image


Top

check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
ENSG00000145592.12,RPL37THCAPathEAG1.0073e-024.9859e-03-0.1281image


Top

check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
ENSG00000145592.12,RPL37CESCEAG3.3123e-021.4283e-021.3111e+07image

Top

3. Enriched editing regions and immune related genes for RPL37


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr5:40829752-40831277:-LGGEERENSG00000149639,SOGA1-0.45441.5504e-211.5908e-20-0.4042imageNAUH;CSTF2T;DDX42;DDX54;DGCR8;DHX9;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LIN28A;LIN28B;LSM11;MOV10;MSI2;NOP56;NOP58;NUMA1;PCBP2;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RNF219;SLTM;SRSF1;SRSF3;SRSF7;TAF15;TARBP2;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YWHAGNAMonocytesGSVA_HALLMARK_MITOTIC_SPINDLE
chr5:40829752-40831277:-LGGEERENSG00000158636,C11orf30-0.44123.4026e-202.5859e-22-0.4211imageNAUH;CSTF2T;DDX42;DDX54;DGCR8;DHX9;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LIN28A;LIN28B;LSM11;MOV10;MSI2;NOP56;NOP58;NUMA1;PCBP2;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RNF219;SLTM;SRSF1;SRSF3;SRSF7;TAF15;TARBP2;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YWHAGNAT_cells_follicular_helperGSVA_HALLMARK_MYOGENESIS
chr5:40829752-40831277:-LGGEERENSG00000171316,CHD7-0.42961.8566e-192.4788e-20-0.4023imageNAUH;CSTF2T;DDX42;DDX54;DGCR8;DHX9;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LIN28A;LIN28B;LSM11;MOV10;MSI2;NOP56;NOP58;NUMA1;PCBP2;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;SLTM;SRSF1;SRSF3;SRSF7;TAF15;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YWHAGCHD7Macrophages_M1GSVA_HALLMARK_MYOGENESIS
chr5:40829752-40831277:-LGGEERENSG00000108771,DHX580.41404.6717e-192.1272e-210.4126imageNCSTF2T;DDX42;DGCR8;EIF4A3;ELAVL1;FBL;FUS;FXR1;HNRNPA1;HNRNPC;HNRNPK;HNRNPU;LSM11;PCBP2;RBFOX2;RBM10;SRSF1;TAF15;U2AF1;U2AF2;UPF1DHX58Macrophages_M1GSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr5:40829752-40831277:-LGGEERENSG00000175414,ARL10-0.42511.0228e-187.6342e-22-0.4168imageNAUH;CSTF2T;DDX42;DDX54;DGCR8;DHX9;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LIN28A;LIN28B;LSM11;MOV10;NOP56;NOP58;NUMA1;PCBP2;RANGAP1;RBFOX2;RBM22;RBM27;RBM5;RNF219;SLTM;SRSF1;SRSF3;SRSF7;TAF15;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YWHAGNAT_cells_follicular_helperGSVA_HALLMARK_XENOBIOTIC_METABOLISM
chr5:40829752-40831277:-LGGEERENSG00000118058,KMT2A-0.42032.4237e-186.0245e-23-0.4269imageNAUH;CSTF2T;DDX42;DDX54;DGCR8;DHX9;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LIN28A;LIN28B;LSM11;MOV10;MSI2;NOP56;NOP58;NUMA1;PCBP2;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RNF219;SLTM;SRSF1;SRSF3;SRSF7;TAF15;TARBP2;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YWHAGNANeutrophilsGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr5:40829752-40831277:-LGGEERENSG00000048649,RSF1-0.41051.9331e-172.2102e-22-0.4218imageNAUH;CSTF2T;DDX42;DDX54;DGCR8;DHX9;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LIN28A;LIN28B;LSM11;MOV10;MSI2;NOP56;NOP58;NUMA1;PCBP2;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RNF219;SLTM;SRSF1;SRSF3;SRSF7;TAF15;TARBP2;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YWHAGNAT_cells_CD8GSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr5:40829752-40831277:-LGGEERENSG00000068796,KIF2A-0.40454.2024e-172.5464e-22-0.4212imageNAUH;CSTF2T;DDX54;DGCR8;DHX9;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;HNRNPA1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LIN28A;LIN28B;LSM11;MOV10;MSI2;NOP56;NOP58;PCBP2;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;SLTM;SRSF1;SRSF3;SRSF7;TAF15;TARBP2;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2NANeutrophilsGSVA_HALLMARK_MITOTIC_SPINDLE
chr5:40829752-40831277:-LGGEERENSG00000100393,EP300-0.40664.4906e-171.9440e-21-0.4130imageNAUH;CSTF2T;DDX42;DDX54;DGCR8;DHX9;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LIN28A;LIN28B;LSM11;MOV10;MSI2;NOP56;NOP58;NUMA1;PCBP2;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RNF219;SLTM;SRSF1;SRSF3;SRSF7;TAF15;TARBP2;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YWHAGEP300T_cells_follicular_helperGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr5:40829752-40831277:-LGGEERENSG00000243156,MICAL3-0.40475.2049e-171.6907e-21-0.4135imageNAUH;CSTF2T;DDX42;DDX54;DGCR8;DHX9;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LIN28A;LIN28B;LSM11;MOV10;MSI2;NOP56;NOP58;NUMA1;PCBP2;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RNF219;SLTM;SRSF1;SRSF3;SRSF7;TAF15;TARBP2;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YWHAGNAMacrophages_M1GSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY

More results



Top

4. Enriched editing regions and immune related splicing for RPL37


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000145592.12,RPL37
GBMEAGIRENSG00000145592.9chr540827702:40827951:40832441:408325130.51016.3033e-075.6953e-110.4967imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;METTL14;METTL3;MOV10;MSI1;MSI2;NCBP3;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM39;RBM47;RBM5;RBM6;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAT_cells_CD8GSVA_HALLMARK_MYC_TARGETS_V1
chr5:40829752-40831277:-
LGGEERA3ENSG00000115355.11chr255291675:55291775:55288177:55288355:55288177:552911640.37705.0397e-131.4993e-200.4044imageNAUH;CSTF2T;DDX42;DDX54;DGCR8;DHX9;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;GNL3;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LIN28A;LIN28B;LSM11;MOV10;MSI2;NOP56;NOP58;NUMA1;PCBP2;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RNF219;SLTM;SRSF1;SRSF3;SRSF7;TAF15;TARBP2;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YWHAGCCDC88AMacrophages_M2GSVA_HALLMARK_HEDGEHOG_SIGNALING
ENSG00000145592.12,RPL37
THYMEAGIRENSG00000105058.7chr1916185417:16185516:16185627:16185765-0.12414.9609e-024.2077e-06-0.5032imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CAPRIN1;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM27;RBM47;RTCB;SAFB2;SF3A3;SF3B4;SLTM;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;ZC3H7B;ZNF184NAEosinophils
ENSG00000145592.12,RPL37
THYMEAGA5ENSG00000167895.10chr1778132358:78132465:78130777:78132030:78130777:78132214-0.28774.3080e-027.6517e-06-0.4972imageNADAR;AUH;BUD13;CELF2;CSTF2T;DDX3X;DDX42;DGCR8;DKC1;EIF4A3;EIF4G2;FAM120A;FBL;FUS;GNL3;GTF2F1;HNRNPA1;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHSRP;LIN28B;LSM11;NONO;NOP56;NOP58;PRPF8;PTBP1;RBFOX2;RBM27;RBM5;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;XRN2NADendritic_cells_activatedGSVA_HALLMARK_ESTROGEN_RESPONSE_LATE
ENSG00000145592.12,RPL37
THYMEAGMEXENSG00000162522.6chr132769672:32769786:32769879:32770110:32772356:32772441:32772864:327749700.34892.0954e-023.3964e-050.4408imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CAPRIN1;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP7;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZNF184NANK_cells_activatedGSVA_HALLMARK_PROTEIN_SECRETION
ENSG00000145592.12,RPL37
THYMEAGIRENSG00000122257.14chr1624548944:24553557:24555614:24555703-0.37701.3453e-025.0236e-05-0.4182imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI1;MSI2;NCBP3;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM5;RBM6;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAMacrophages_M0GSVA_HALLMARK_ESTROGEN_RESPONSE_EARLY
ENSG00000145592.12,RPL37
THYMEAGMEXENSG00000174718.7chr1231970188:31970356:31980877:31986007:31987244:31987322:31992377:319929410.40508.6922e-035.1780e-090.5529imageNADAR;ALYREF;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;METTL14;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;RTCB;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAMast_cells_restingGSVA_HALLMARK_PEROXISOME
ENSG00000145592.12,RPL37
THYMEAGIRENSG00000185658.9chr2139296264:39296363:39298431:39298582-0.31844.2150e-025.4596e-08-0.5229imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI1;MSI2;NCBP3;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM5;RBM6;RC3H1;RNF219;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YWHAG;ZC3H7B;ZNF184NANK_cells_activatedGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
ENSG00000145592.12,RPL37
THYMEAGIRENSG00000185404.12chr2230400954:230401063:230401365:2304014430.32823.3118e-022.2135e-040.4115imageNACIN1;ADAR;AUH;BCCIP;BUD13;CELF2;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DKC1;EIF4A3;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHSRP;LIN28B;LSM11;MSI1;MSI2;NONO;NOP56;NPM1;PCBP2;PRPF8;PTBP1;RBFOX2;RBM22;RBM27;RBM47;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1NANK_cells_activatedGSVA_HALLMARK_FATTY_ACID_METABOLISM
ENSG00000145592.12,RPL37
THYMEAGA5ENSG00000108848.11chr1750752199:50752282:50750500:50750852:50750500:50751375-0.26192.9995e-022.5011e-05-0.4354imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI1;MSI2;NCBP3;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM39;RBM47;RBM5;RBM6;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YWHAG;ZC3H7B;ZNF184LUC7L3Dendritic_cells_restingGSVA_HALLMARK_PEROXISOME

More results



Top

5. Enriched editing regions and immune infiltration for RPL37


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
ENSG00000145592.12,RPL37ACCEAGMonocytes8.1468e-030.3666image
chr5:40829752-40831277:-BLCAEEREosinophils8.6739e-03-0.5573image
chr5:40825778-40826975:-BRCAEERT_cells_CD89.6446e-03-0.0967image
ENSG00000145592.12,RPL37BRCAEAGT_cells_regulatory_(Tregs)1.7372e-04-0.1320image
chr5:40829752-40831277:-COADEERMast_cells_activated8.3549e-030.5724image
ENSG00000145592.12,RPL37COADEAGDendritic_cells_activated7.6693e-030.3383image
ENSG00000145592.12,RPL37DLBCEAGDendritic_cells_activated1.8789e-020.3952image
chr5:40829752-40831277:-ESCAEERMonocytes2.7483e-03-0.2881image
ENSG00000145592.12,RPL37ESCAEAGMacrophages_M09.3911e-040.2857image
chr5:40829752-40831277:-GBMEERDendritic_cells_activated4.6589e-040.3757image
ENSG00000145592.12,RPL37GBMEAGT_cells_CD4_memory_resting1.4438e-020.1925image
ENSG00000145592.12,RPL37KICHEAGB_cells_memory1.5264e-020.3286image
chr5:40829752-40831277:-KIRCEERT_cells_gamma_delta2.4261e-02-0.1991image
ENSG00000145592.12,RPL37KIRCEAGT_cells_regulatory_(Tregs)1.2178e-04-0.2416image
chr5:40829752-40831277:-KIRPEERNK_cells_activated1.5492e-02-0.4530image
ENSG00000145592.12,RPL37KIRPEAGPlasma_cells3.6767e-040.2693image
ENSG00000145592.12,RPL37LAMLEAGMacrophages_M02.4259e-040.3881image
chr5:40829752-40831277:-LGGEERMacrophages_M12.1287e-050.1915image
ENSG00000145592.12,RPL37LGGEAGMacrophages_M11.9671e-040.1615image
ENSG00000145592.12,RPL37LIHCEAGMacrophages_M03.7948e-03-0.2290image
ENSG00000145592.12,RPL37LUADEAGT_cells_follicular_helper1.0842e-02-0.1767image
chr5:40829752-40831277:-LUSCEERT_cells_CD4_memory_activated2.4123e-030.3094image
ENSG00000145592.12,RPL37LUSCEAGT_cells_CD4_memory_activated3.9450e-030.2045image
ENSG00000145592.12,RPL37MESOEAGT_cells_CD4_memory_activated9.1946e-030.3800image
chr5:40829752-40831277:-OVEERT_cells_CD81.5593e-030.2668image
ENSG00000145592.12,RPL37PAADEAGMonocytes9.2825e-030.2743image
chr5:40829752-40831277:-PCPGEERMacrophages_M24.8821e-020.2954image
ENSG00000145592.12,RPL37PCPGEAGNeutrophils3.0911e-030.2616image
chr5:40829752-40831277:-PRADEEREosinophils2.9062e-020.1449image
ENSG00000145592.12,RPL37PRADEAGDendritic_cells_resting6.4403e-050.1846image
ENSG00000145592.12,RPL37SARCEAGMacrophages_M06.2670e-03-0.2187image
chr5:40829752-40831277:-SKCMEERPlasma_cells6.8731e-030.2455image
chr5:40825778-40826975:-STADEEREosinophils1.4951e-020.1797image
chr5:40829752-40831277:-STADEERMonocytes1.2536e-020.1700image
ENSG00000145592.12,RPL37STADEAGMacrophages_M01.8867e-02-0.1413image
ENSG00000145592.12,RPL37TGCTEAGMonocytes3.4985e-050.5318image
chr5:40829752-40831277:-THCAEERT_cells_CD4_memory_resting4.9751e-020.1200image
ENSG00000145592.12,RPL37THCAEAGT_cells_regulatory_(Tregs)1.3335e-04-0.1733image
ENSG00000145592.12,RPL37THYMEAGEosinophils2.9674e-050.4105image
ENSG00000145592.12,RPL37UCECEAGB_cells_naive2.9815e-020.2185image
ENSG00000145592.12,RPL37UVMEAGPlasma_cells9.5857e-030.3215image


Top

6. Enriched editing regions and immune gene sets for RPL37


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot
ENSG00000145592.12,RPL37LIHCEAG2.7494e-02image4.3054e-020.1612image


Top

check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot
ENSG00000145592.12,RPL37LUADEAG1.8098e-030.21561.5752e-030.21832.0309e-030.21333.1457e-030.2043image


Top

check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
ENSG00000145592.12,RPL37ACCGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG1.6453e-02-0.3344image
ENSG00000145592.12,RPL37BLCAGSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALINGEAG9.0630e-030.2090image
chr5:40829752-40831277:-BLCAGSVA_HALLMARK_KRAS_SIGNALING_DNEER8.7703e-030.5566image
chr5:40825778-40826975:-BRCAGSVA_HALLMARK_PROTEIN_SECRETIONEER1.2562e-030.1204image
chr5:40829752-40831277:-BRCAGSVA_HALLMARK_APOPTOSISEER4.0452e-050.2146image
ENSG00000145592.12,RPL37BRCAGSVA_HALLMARK_PROTEIN_SECRETIONEAG9.7558e-090.2005image
chr5:40829752-40831277:-COADGSVA_HALLMARK_FATTY_ACID_METABOLISMEER2.7315e-02-0.4927image
ENSG00000145592.12,RPL37COADGSVA_HALLMARK_P53_PATHWAYEAG8.1003e-04-0.4177image
chr5:40829752-40831277:-ESCAGSVA_HALLMARK_ADIPOGENESISEER6.3276e-030.2636image
ENSG00000145592.12,RPL37GBMGSVA_HALLMARK_NOTCH_SIGNALINGEAG1.2358e-040.2980image
chr5:40829752-40831277:-GBMGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER1.8993e-040.3986image
ENSG00000145592.12,RPL37HNSCGSVA_HALLMARK_DNA_REPAIREAG3.3039e-02-0.1742image
ENSG00000145592.12,RPL37KICHGSVA_HALLMARK_HEME_METABOLISMEAG4.4089e-030.3816image
ENSG00000145592.12,RPL37KIRCGSVA_HALLMARK_MITOTIC_SPINDLEEAG1.1906e-050.2741image
chr5:40829752-40831277:-KIRCGSVA_HALLMARK_PANCREAS_BETA_CELLSEER8.2608e-100.5094image
ENSG00000145592.12,RPL37KIRPGSVA_HALLMARK_DNA_REPAIREAG2.9646e-03-0.2259image
chr5:40829752-40831277:-KIRPGSVA_HALLMARK_KRAS_SIGNALING_DNEER2.6509e-050.7065image
ENSG00000145592.12,RPL37LAMLGSVA_HALLMARK_MYC_TARGETS_V2EAG1.2907e-02-0.2687image
chr5:40829752-40831277:-LGGGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER3.2275e-190.3912image
ENSG00000145592.12,RPL37LGGGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG1.0540e-250.4347image
ENSG00000145592.12,RPL37LIHCGSVA_HALLMARK_COAGULATIONEAG1.3319e-040.2993image
ENSG00000145592.12,RPL37LUADGSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALINGEAG3.4753e-040.2463image
ENSG00000145592.12,RPL37LUSCGSVA_HALLMARK_UNFOLDED_PROTEIN_RESPONSEEAG2.9064e-020.1556image
chr5:40829752-40831277:-LUSCGSVA_HALLMARK_PEROXISOMEEER1.1523e-030.3302image
ENSG00000145592.12,RPL37MESOGSVA_HALLMARK_UNFOLDED_PROTEIN_RESPONSEEAG9.7585e-03-0.3772image
chr5:40829752-40831277:-OVGSVA_HALLMARK_PANCREAS_BETA_CELLSEER2.1234e-060.3910image
ENSG00000145592.12,RPL37OVGSVA_HALLMARK_SPERMATOGENESISEAG4.1887e-02-0.1444image
ENSG00000145592.12,RPL37PAADGSVA_HALLMARK_SPERMATOGENESISEAG3.1756e-020.2278image
ENSG00000145592.12,RPL37PCPGGSVA_HALLMARK_MITOTIC_SPINDLEEAG6.7170e-040.2990image
chr5:40829752-40831277:-PRADGSVA_HALLMARK_G2M_CHECKPOINTEER1.9166e-03-0.2049image
ENSG00000145592.12,RPL37PRADGSVA_HALLMARK_MITOTIC_SPINDLEEAG7.1296e-100.2814image
ENSG00000145592.12,RPL37READGSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALINGEAG2.2134e-030.6172image
ENSG00000145592.12,RPL37SARCGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG6.1127e-03-0.2193image
chr5:40829752-40831277:-SARCGSVA_HALLMARK_UV_RESPONSE_UPEER4.1344e-030.5005image
chr5:40829752-40831277:-SKCMGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER4.3282e-040.3163image
ENSG00000145592.12,RPL37SKCMGSVA_HALLMARK_ANGIOGENESISEAG3.1030e-02-0.1318image
ENSG00000145592.12,RPL37STADGSVA_HALLMARK_ALLOGRAFT_REJECTIONEAG6.5525e-030.1633image
chr5:40829752-40831277:-STADGSVA_HALLMARK_ALLOGRAFT_REJECTIONEER1.8195e-030.2115image
chr5:40825778-40826975:-STADGSVA_HALLMARK_MITOTIC_SPINDLEEER2.7718e-03-0.2200image
ENSG00000145592.12,RPL37TGCTGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG8.0385e-03-0.3571image
chr5:40829752-40831277:-THCAGSVA_HALLMARK_GLYCOLYSISEER7.1528e-050.2401image
ENSG00000145592.12,RPL37THCAGSVA_HALLMARK_UV_RESPONSE_DNEAG8.2906e-090.2589image
ENSG00000145592.12,RPL37THYMGSVA_HALLMARK_FATTY_ACID_METABOLISMEAG2.2413e-03-0.3068image
ENSG00000145592.12,RPL37UCECGSVA_HALLMARK_ANDROGEN_RESPONSEEAG1.0468e-03-0.3246image
ENSG00000145592.12,RPL37UCSGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEAG1.3145e-02-0.5198image
ENSG00000145592.12,RPL37UVMGSVA_HALLMARK_DNA_REPAIREAG2.0832e-02-0.2884image


Top

7. Enriched editing regions and drugs for RPL37


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
ENSG00000145592.12,RPL37ACCAICAREAG3.6575e-040.4799image
chr5:40829752-40831277:-BLCAMetforminEER1.0653e-02-0.5448image
chr5:40825778-40826975:-BRCACyclopamineEER1.2975e-040.1430image
ENSG00000145592.12,RPL37BRCAGW843682XEAG1.5152e-110.2350image
chr5:40829752-40831277:-BRCALapatinibEER2.0420e-04-0.1956image
ENSG00000145592.12,RPL37CESCDMOGEAG6.4012e-030.2750image
chr5:40829752-40831277:-COADJNK.Inhibitor.VIIIEER2.2866e-02-0.5059image
ENSG00000145592.12,RPL37COADJNK.Inhibitor.VIIIEAG3.5516e-03-0.3677image
chr5:40829752-40831277:-ESCAJW.7.52.1EER4.7652e-03-0.2722image
ENSG00000145592.12,RPL37ESCABexaroteneEAG3.2689e-02-0.1868image
chr5:40829752-40831277:-GBMBAY.61.3606EER2.5841e-040.3909image
ENSG00000145592.12,RPL37GBMAZD6482EAG4.1405e-06-0.3538image
ENSG00000145592.12,RPL37HNSCCGP.60474EAG7.9946e-030.2158image
ENSG00000145592.12,RPL37KICHEmbelinEAG2.8677e-03-0.3981image
ENSG00000145592.12,RPL37KIRCBMS.536924EAG1.2949e-080.3520image
chr5:40829752-40831277:-KIRCLenalidomideEER3.6866e-060.3961image
chr5:40829752-40831277:-KIRPGDC0941EER1.5380e-02-0.4534image
ENSG00000145592.12,RPL37KIRPMetforminEAG2.9324e-030.2262image
ENSG00000145592.12,RPL37LAMLATRAEAG3.1524e-020.2335image
ENSG00000145592.12,RPL37LGGLapatinibEAG3.7110e-29-0.4615image
chr5:40829752-40831277:-LGGBAY.61.3606EER4.6718e-160.3570image
ENSG00000145592.12,RPL37LIHCBleomycinEAG8.3249e-080.4119image
ENSG00000145592.12,RPL37LUADKIN001.135EAG2.0958e-02-0.1604image
ENSG00000145592.12,RPL37LUSCCyclopamineEAG1.7803e-02-0.1687image
chr5:40829752-40831277:-LUSCImatinibEER6.2742e-030.2800image
ENSG00000145592.12,RPL37MESOBMS.536924EAG1.6689e-020.3512image
chr5:40829752-40831277:-OVA.770041EER8.1091e-08-0.4374image
ENSG00000145592.12,RPL37OVAZ628EAG2.6887e-03-0.2117image
ENSG00000145592.12,RPL37PAADMG.132EAG6.3153e-040.3573image
chr5:40829752-40831277:-PCPGAKT.inhibitor.VIIIEER2.1001e-02-0.3432image
ENSG00000145592.12,RPL37PCPGBIRB.0796EAG5.6667e-04-0.3029image
chr5:40829752-40831277:-PRADBryostatin.1EER6.2983e-04-0.2252image
ENSG00000145592.12,RPL37PRADBMS.509744EAG7.4028e-100.2811image
ENSG00000145592.12,RPL37SARCDMOGEAG2.0365e-04-0.2941image
chr5:40829752-40831277:-SARCDMOGEER1.9893e-02-0.4161image
chr5:40829752-40831277:-SKCMBI.D1870EER4.5623e-040.3151image
ENSG00000145592.12,RPL37SKCMGDC.0449EAG7.7429e-040.2041image
ENSG00000145592.12,RPL37STADAZD8055EAG4.6451e-03-0.1699image
chr5:40829752-40831277:-STADEHT.1864EER2.7103e-03-0.2036image
chr5:40825778-40826975:-STADBosutinibEER1.8042e-020.1747image
ENSG00000145592.12,RPL37TGCTBortezomibEAG1.8694e-020.3191image
chr5:40829752-40831277:-THCABicalutamideEER4.7279e-04-0.2121image
ENSG00000145592.12,RPL37THCABMS.536924EAG3.3869e-140.3375image
ENSG00000145592.12,RPL37THYMLapatinibEAG9.4982e-04-0.3304image
ENSG00000145592.12,RPL37UCECAP.24534EAG3.8079e-03-0.2883image
ENSG00000145592.12,RPL37UCSGW843682XEAG2.2717e-020.4832image
ENSG00000145592.12,RPL37UVMABT.263EAG5.9542e-03-0.3402image


Top

check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType