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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: RPL27A (ImmuneEditome ID:6157)

1. Gene summary of enriched editing regions for RPL27A

check button Gene summary
Gene informationGene symbol

RPL27A

Gene ID

6157

GeneSynonymsL27A|uL15
GeneCytomap

11p15.4

GeneTypeprotein-coding
GeneDescription60S ribosomal protein L27a|large ribosomal subunit protein uL15
GeneModificationdate20230409
UniprotIDP46776;E9PJD9;E9PLX7;E9PKT2;E9PLL6
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr11:8686238-8687804:+ENST00000314138.9ENSG00000166441.11RPL27AUTR3AluSq,AluSp,AluY,MER5A,MIRbchr11:8686238-8687804:+.alignment


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2. Tumor-specific enriched editing regions for RPL27A


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chr11:8686238-8687804:+HNSCEER4.9177e-03image
ENSG00000166441.11,RPL27AHNSCEAG4.9198e-03image


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
chr11:8686238-8687804:+PAADPathEER2.8644e-021.8444e-020.1780image
ENSG00000166441.11,RPL27APAADPathEAG2.8644e-021.8444e-020.1780image
chr11:8686238-8687804:+THCAPathEER1.1064e-021.0027e-020.1147image
ENSG00000166441.11,RPL27ATHCAPathEAG1.1064e-021.0027e-020.1147image


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
chr11:8686238-8687804:+KIRPEER3.5795e-032.1551e-021.8307e-03image
ENSG00000166441.11,RPL27AKIRPEAG3.5795e-032.1551e-021.8307e-03image
chr11:8686238-8687804:+LUSCEER1.5796e-024.8559e-021.5785e-01image
ENSG00000166441.11,RPL27ALUSCEAG1.5796e-024.8559e-021.5785e-01image
chr11:8686238-8687804:+UCECEER1.2232e-022.3836e-024.8084e-02image
ENSG00000166441.11,RPL27AUCECEAG1.2232e-022.3836e-024.8084e-02image

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3. Enriched editing regions and immune related genes for RPL27A


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr11:8686238-8687804:+UCECEERENSG00000234769,WASH4P0.28152.0561e-023.9263e-090.4300imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_PROTEIN_SECRETION
chr11:8686238-8687804:+UCECEERENSG00000155287,SLC25A280.26262.4368e-021.4008e-080.4159imageNBUD13;CPSF6;CSTF2T;DDX54;DGCR8;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;GNL3;GTF2F1;HNRNPA1;HNRNPC;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;ILF3;KHDRBS1;LIN28;LIN28B;LSM11;NOP56;NOP58;NUMA1;PTBP1;RANGAP1;RBFOX2;SAFB2;SLTM;SMNDC1;SND1;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;XRN2;ZNF184NAT_cells_CD8GSVA_HALLMARK_PROTEIN_SECRETION
chr11:8686238-8687804:+UCECEERENSG00000226396,RP5-1056L3.30.26503.0955e-021.6651e-110.4844imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_PROTEIN_SECRETION
chr11:8686238-8687804:+UCECEERENSG00000110719,TCIRG10.25234.1155e-022.8244e-080.4078imageNAUH;BUD13;CPSF6;CSTF2T;DDX54;DGCR8;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;GNL3;GTF2F1;HNRNPA1;HNRNPC;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;ILF3;KHDRBS1;KHSRP;LIN28;LIN28B;LSM11;NONO;NOP58;PTBP1;RBFOX2;SAFB2;SLTM;SMNDC1;SND1;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;XRN2;ZNF184TCIRG1T_cells_regulatory_(Tregs)GSVA_HALLMARK_ALLOGRAFT_REJECTION
chr11:8686238-8687804:+UCECEERENSG00000204305,AGER0.25294.1448e-027.0531e-100.4482imageNAUH;BUD13;CPSF6;CSTF2T;DGCR8;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;GTF2F1;HNRNPA1;HNRNPC;HNRNPU;IGF2BP2;KHSRP;LSM11;NOP58;NUMA1;PTBP1;RBFOX2;SAFB2;SLTM;SMNDC1;SND1;SRSF7;SRSF9;TAF15;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;XRN2AGERT_cells_regulatory_(Tregs)GSVA_HALLMARK_PROTEIN_SECRETION
chr11:8686238-8687804:+UCECEERENSG00000220201,ZGLP10.25064.6035e-026.4789e-100.4490imageNBUD13;CSTF2T;DDX54;DGCR8;EIF4A3;ELAVL1;FAM120A;FBL;GTF2F1;HNRNPA1;HNRNPC;HNRNPM;HNRNPU;IGF2BP1;ILF3;KHDRBS1;LSM11;NOP58;NUMA1;RANGAP1;RBFOX2;SLTM;SRSF7;SRSF9;TAF15;TIA1;U2AF1;U2AF2;ZNF184NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_PROTEIN_SECRETION
chr11:8686238-8687804:+THYMEERENSG00000141956,PRDM15-0.41741.6720e-045.4585e-06-0.4048imageNAUH;BUD13;CPSF6;CSTF2T;DDX54;DGCR8;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;GNL3;GTF2F1;HNRNPA1;HNRNPC;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;ILF3;KHDRBS1;KHSRP;LIN28;LIN28B;LSM11;NONO;NOP56;NOP58;NUMA1;PTBP1;RANGAP1;RBFOX2;RNF219;SAFB2;SLTM;SMNDC1;SND1;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;XRN2;ZNF184NAB_cells_memoryGSVA_HALLMARK_XENOBIOTIC_METABOLISM
chr11:8686238-8687804:+THYMEERENSG00000173473,SMARCC1-0.40083.7892e-047.0227e-06-0.4004imageNAUH;BUD13;CPSF6;CSTF2T;DDX54;DGCR8;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;GNL3;GTF2F1;HNRNPA1;HNRNPC;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;ILF3;KHDRBS1;KHSRP;LIN28;LIN28B;LSM11;NONO;NOP56;NOP58;NUMA1;PTBP1;RANGAP1;RBFOX2;RNF219;SAFB2;SLTM;SMNDC1;SND1;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;XRN2;ZNF184NAT_cells_CD4_naiveGSVA_HALLMARK_MITOTIC_SPINDLE
chr11:8686238-8687804:+THYMEERENSG00000010030,ETV70.39424.1840e-041.2950e-070.4630imageNDGCR8;EIF4A3;ELAVL1;FBL;IGF2BP2;NOP58;PTBP1;RBFOX2;TAF15;TARDBP;U2AF2NAT_cells_gamma_deltaGSVA_HALLMARK_ESTROGEN_RESPONSE_LATE
chr11:8686238-8687804:+THYMEERENSG00000203950,FAM127B0.33693.5284e-033.8351e-080.4799imageNCPSF6;CSTF2T;DDX54;DGCR8;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;GTF2F1;HNRNPC;HNRNPM;HNRNPUL1;IGF2BP1;IGF2BP2;ILF3;KHDRBS1;KHSRP;LIN28;LIN28B;LSM11;NONO;NOP56;NOP58;NUMA1;PTBP1;RANGAP1;RBFOX2;RNF219;SAFB2;SLTM;SMNDC1;SND1;SRSF7;TAF15;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;XRN2;ZNF184NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_G2M_CHECKPOINT

More results



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4. Enriched editing regions and immune related splicing for RPL27A


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr11:8686238-8687804:+
GBMEERMEXENSG00000109390.7chr4139295731:139295960:139297384:139297456:139300601:139300704:139300963:1393012040.24624.2295e-027.1425e-070.4202imageNAUH;BUD13;CPSF6;CSTF2T;DDX54;DGCR8;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;GNL3;GTF2F1;HNRNPA1;HNRNPC;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;ILF3;KHDRBS1;KHSRP;LIN28;LIN28B;LSM11;NONO;NOP56;NOP58;NUMA1;PTBP1;RANGAP1;RBFOX2;RNF219;SAFB2;SLTM;SMNDC1;SND1;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;XRN2;ZNF184NAT_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSE
ENSG00000166441.11,RPL27A
GBMEAGMEXENSG00000109390.7chr4139295731:139295960:139297384:139297456:139300601:139300704:139300963:1393012040.24644.8700e-026.9584e-070.4206imageNACIN1;ADAR;AUH;BCCIP;BUD13;CAPRIN1;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL3;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RNF219;RTCB;SAFB2;SBDS;SF3A3;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YWHAG;ZNF184NAT_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSE
ENSG00000166441.11,RPL27A
SKCMEAGMEXENSG00000129657.10chr1777215792:77215805:77215984:77216062:77216075:77216387:77216413:772168020.09109.5667e-032.7144e-160.4325imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM6;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;WTAP;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000166441.11,RPL27A
SKCMEAGMEXENSG00000129657.10chr1777215792:77215805:77215984:77216062:77216101:77216387:77216413:772168020.09099.6329e-032.8072e-160.4323imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM6;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;WTAP;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000166441.11,RPL27A
SKCMEAGMEXENSG00000129657.10chr1777215792:77215805:77215984:77216062:77216062:77216387:77216413:772168020.09099.7835e-031.5989e-160.4349imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM6;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;WTAP;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000166441.11,RPL27A
SKCMEAGMEXENSG00000129657.10chr1777215792:77215805:77215984:77216049:77216049:77216387:77216413:772168020.08063.4011e-022.5130e-150.4195imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM6;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;WTAP;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000166441.11,RPL27A
SKCMEAGMEXENSG00000129657.10chr1777215792:77215805:77215984:77216049:77216088:77216387:77216413:772168020.08043.5013e-022.7602e-150.4189imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM6;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;WTAP;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000166441.11,RPL27A
SKCMEAGMEXENSG00000129657.10chr1777215792:77215805:77215984:77216088:77216088:77216387:77216413:772168020.08043.5013e-022.7602e-150.4189imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM6;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;WTAP;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000166441.11,RPL27A
SKCMEAGMEXENSG00000129657.10chr1777215792:77215805:77215984:77216088:77216192:77216387:77216413:772168020.08043.5013e-023.3258e-150.4178imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM6;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;WTAP;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAGSVA_HALLMARK_MITOTIC_SPINDLE
ENSG00000166441.11,RPL27A
SKCMEAGMEXENSG00000129657.10chr1777215792:77215805:77215984:77216088:77216101:77216387:77216413:772168020.08043.5206e-023.3971e-150.4177imageNACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;METTL14;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM6;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;WTAP;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAGSVA_HALLMARK_MITOTIC_SPINDLE

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5. Enriched editing regions and immune infiltration for RPL27A


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chr11:8686238-8687804:+ACCEERNK_cells_activated3.6868e-030.3500image
ENSG00000166441.11,RPL27AACCEAGNK_cells_activated3.6868e-030.3500image
chr11:8686238-8687804:+BLCAEERMonocytes2.8385e-040.1847image
ENSG00000166441.11,RPL27ABLCAEAGMonocytes2.8351e-040.1847image
chr11:8686238-8687804:+BRCAEERMacrophages_M13.4312e-020.0654image
ENSG00000166441.11,RPL27ABRCAEAGMacrophages_M13.4312e-020.0654image
chr11:8686238-8687804:+CESCEERT_cells_regulatory_(Tregs)1.9145e-030.1837image
ENSG00000166441.11,RPL27ACESCEAGT_cells_regulatory_(Tregs)1.9145e-030.1837image
chr11:8686238-8687804:+CHOLEERMacrophages_M22.2919e-03-0.5055image
ENSG00000166441.11,RPL27ACHOLEAGMacrophages_M22.2919e-03-0.5055image
chr11:8686238-8687804:+COADEERT_cells_follicular_helper9.3732e-03-0.1584image
ENSG00000166441.11,RPL27ACOADEAGT_cells_follicular_helper2.0971e-02-0.1407image
chr11:8686238-8687804:+ESCAEERDendritic_cells_activated4.5808e-020.1581image
ENSG00000166441.11,RPL27AESCAEAGDendritic_cells_activated4.7531e-020.1569image
chr11:8686238-8687804:+KICHEERMacrophages_M02.5001e-020.2823image
ENSG00000166441.11,RPL27AKICHEAGMacrophages_M02.5001e-020.2823image
chr11:8686238-8687804:+KIRCEERMacrophages_M21.0499e-03-0.1679image
ENSG00000166441.11,RPL27AKIRCEAGMacrophages_M21.0499e-03-0.1679image
chr11:8686238-8687804:+KIRPEERT_cells_regulatory_(Tregs)2.3170e-02-0.1354image
ENSG00000166441.11,RPL27AKIRPEAGT_cells_regulatory_(Tregs)2.3170e-02-0.1354image
chr11:8686238-8687804:+LAMLEERMast_cells_resting2.9897e-020.1810image
ENSG00000166441.11,RPL27ALAMLEAGMast_cells_resting2.9897e-020.1810image
chr11:8686238-8687804:+LGGEERMast_cells_resting3.8761e-03-0.1256image
ENSG00000166441.11,RPL27ALGGEAGMast_cells_resting3.7869e-03-0.1259image
chr11:8686238-8687804:+LIHCEERT_cells_gamma_delta3.3694e-020.1175image
ENSG00000166441.11,RPL27ALIHCEAGT_cells_gamma_delta3.3694e-020.1175image
chr11:8686238-8687804:+LUADEERT_cells_gamma_delta1.2650e-040.1748image
ENSG00000166441.11,RPL27ALUADEAGT_cells_gamma_delta1.2687e-040.1748image
chr11:8686238-8687804:+LUSCEERMast_cells_resting3.8239e-02-0.0959image
ENSG00000166441.11,RPL27ALUSCEAGMast_cells_resting3.8284e-02-0.0959image
chr11:8686238-8687804:+MESOEERMast_cells_resting3.2559e-02-0.2363image
ENSG00000166441.11,RPL27AMESOEAGMast_cells_resting3.2559e-02-0.2363image
chr11:8686238-8687804:+OVEERT_cells_CD81.6738e-060.2764image
ENSG00000166441.11,RPL27AOVEAGT_cells_CD81.7626e-060.2759image
chr11:8686238-8687804:+PRADEERB_cells_memory1.2227e-020.1123image
ENSG00000166441.11,RPL27APRADEAGB_cells_memory1.2227e-020.1123image
chr11:8686238-8687804:+READEERT_cells_gamma_delta8.3023e-030.2708image
ENSG00000166441.11,RPL27AREADEAGT_cells_gamma_delta8.3023e-030.2708image
chr11:8686238-8687804:+SKCMEERT_cells_follicular_helper1.4259e-020.1155image
ENSG00000166441.11,RPL27ASKCMEAGT_cells_follicular_helper1.4952e-020.1147image
chr11:8686238-8687804:+STADEERNK_cells_activated4.5883e-040.1830image
ENSG00000166441.11,RPL27ASTADEAGNK_cells_activated4.4438e-040.1834image
chr11:8686238-8687804:+TGCTEERB_cells_naive3.1260e-02-0.1828image
ENSG00000166441.11,RPL27ATGCTEAGB_cells_naive3.1260e-02-0.1828image
chr11:8686238-8687804:+THCAEERB_cells_naive3.2494e-03-0.1309image
ENSG00000166441.11,RPL27ATHCAEAGB_cells_naive3.2494e-03-0.1309image
chr11:8686238-8687804:+THYMEERT_cells_gamma_delta1.8583e-040.3375image
ENSG00000166441.11,RPL27ATHYMEAGT_cells_gamma_delta1.8583e-040.3375image
chr11:8686238-8687804:+UCECEERMacrophages_M03.8832e-02-0.1577image
ENSG00000166441.11,RPL27AUCECEAGMacrophages_M03.9562e-02-0.1571image


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6. Enriched editing regions and immune gene sets for RPL27A


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot
chr11:8686238-8687804:+UCECEER3.8926e-03-0.21901.5066e-03-0.24023.4993e-03-0.22152.5245e-02-0.1706image
ENSG00000166441.11,RPL27AUCECEAG3.8445e-03-0.21931.5572e-03-0.23953.5539e-03-0.22112.4457e-02-0.1715image


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
chr11:8686238-8687804:+ACCGSVA_HALLMARK_PANCREAS_BETA_CELLSEER3.5120e-02-0.2579image
ENSG00000166441.11,RPL27AACCGSVA_HALLMARK_PANCREAS_BETA_CELLSEAG3.5120e-02-0.2579image
chr11:8686238-8687804:+BLCAGSVA_HALLMARK_UV_RESPONSE_DNEER2.4527e-02-0.1150image
ENSG00000166441.11,RPL27ABLCAGSVA_HALLMARK_UV_RESPONSE_DNEAG2.4483e-02-0.1151image
ENSG00000166441.11,RPL27ABRCAGSVA_HALLMARK_KRAS_SIGNALING_DNEAG1.7787e-020.0733image
chr11:8686238-8687804:+BRCAGSVA_HALLMARK_KRAS_SIGNALING_DNEER1.7787e-020.0733image
chr11:8686238-8687804:+CESCGSVA_HALLMARK_XENOBIOTIC_METABOLISMEER4.0207e-02-0.1220image
ENSG00000166441.11,RPL27ACESCGSVA_HALLMARK_XENOBIOTIC_METABOLISMEAG4.0207e-02-0.1220image
ENSG00000166441.11,RPL27ACOADGSVA_HALLMARK_DNA_REPAIREAG4.7014e-03-0.1719image
chr11:8686238-8687804:+COADGSVA_HALLMARK_MYC_TARGETS_V1EER3.5600e-02-0.1284image
ENSG00000166441.11,RPL27ADLBCGSVA_HALLMARK_SPERMATOGENESISEAG1.9168e-02-0.3370image
chr11:8686238-8687804:+DLBCGSVA_HALLMARK_SPERMATOGENESISEER1.9168e-02-0.3370image
chr11:8686238-8687804:+GBMGSVA_HALLMARK_MYOGENESISEER1.4604e-020.1898image
ENSG00000166441.11,RPL27AGBMGSVA_HALLMARK_MYOGENESISEAG1.4373e-020.1903image
chr11:8686238-8687804:+HNSCGSVA_HALLMARK_PROTEIN_SECRETIONEER1.4656e-02-0.1115image
ENSG00000166441.11,RPL27AHNSCGSVA_HALLMARK_PROTEIN_SECRETIONEAG1.4651e-02-0.1115image
chr11:8686238-8687804:+KICHGSVA_HALLMARK_APICAL_SURFACEEER1.7257e-02-0.2991image
ENSG00000166441.11,RPL27AKICHGSVA_HALLMARK_APICAL_SURFACEEAG1.7257e-02-0.2991image
ENSG00000166441.11,RPL27AKIRCGSVA_HALLMARK_HYPOXIAEAG2.4155e-04-0.1878image
chr11:8686238-8687804:+KIRCGSVA_HALLMARK_HYPOXIAEER2.4155e-04-0.1878image
chr11:8686238-8687804:+KIRPGSVA_HALLMARK_MYC_TARGETS_V2EER4.1094e-03-0.1707image
ENSG00000166441.11,RPL27AKIRPGSVA_HALLMARK_MYC_TARGETS_V2EAG4.1094e-03-0.1707image
ENSG00000166441.11,RPL27ALAMLGSVA_HALLMARK_G2M_CHECKPOINTEAG6.0379e-04-0.2824image
chr11:8686238-8687804:+LAMLGSVA_HALLMARK_G2M_CHECKPOINTEER6.0379e-04-0.2824image
ENSG00000166441.11,RPL27ALGGGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG5.5601e-050.1746image
chr11:8686238-8687804:+LGGGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER4.8363e-050.1760image
chr11:8686238-8687804:+LIHCGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEER7.4394e-030.1478image
ENSG00000166441.11,RPL27ALIHCGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEAG7.4394e-030.1478image
chr11:8686238-8687804:+LUSCGSVA_HALLMARK_BILE_ACID_METABOLISMEER5.1105e-03-0.1294image
ENSG00000166441.11,RPL27ALUSCGSVA_HALLMARK_BILE_ACID_METABOLISMEAG5.1095e-03-0.1294image
chr11:8686238-8687804:+MESOGSVA_HALLMARK_MYC_TARGETS_V1EER5.4182e-04-0.3738image
ENSG00000166441.11,RPL27AMESOGSVA_HALLMARK_MYC_TARGETS_V1EAG5.4182e-04-0.3738image
chr11:8686238-8687804:+OVGSVA_HALLMARK_MITOTIC_SPINDLEEER4.4955e-05-0.2368image
ENSG00000166441.11,RPL27AOVGSVA_HALLMARK_MITOTIC_SPINDLEEAG4.1808e-05-0.2378image
chr11:8686238-8687804:+PAADGSVA_HALLMARK_ADIPOGENESISEER1.4645e-03-0.2374image
ENSG00000166441.11,RPL27APAADGSVA_HALLMARK_ADIPOGENESISEAG1.4645e-03-0.2374image
ENSG00000166441.11,RPL27APCPGGSVA_HALLMARK_MITOTIC_SPINDLEEAG7.8051e-03-0.1994image
chr11:8686238-8687804:+PCPGGSVA_HALLMARK_MITOTIC_SPINDLEEER7.8051e-03-0.1994image
chr11:8686238-8687804:+PRADGSVA_HALLMARK_MITOTIC_SPINDLEEER2.8871e-04-0.1620image
ENSG00000166441.11,RPL27APRADGSVA_HALLMARK_MITOTIC_SPINDLEEAG2.8871e-04-0.1620image
chr11:8686238-8687804:+READGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER4.1172e-02-0.2110image
ENSG00000166441.11,RPL27AREADGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG4.1172e-02-0.2110image
chr11:8686238-8687804:+SKCMGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER9.7389e-030.1217image
ENSG00000166441.11,RPL27ASKCMGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG1.0302e-020.1208image
chr11:8686238-8687804:+STADGSVA_HALLMARK_PROTEIN_SECRETIONEER4.8186e-04-0.1823image
ENSG00000166441.11,RPL27ASTADGSVA_HALLMARK_PROTEIN_SECRETIONEAG4.6666e-04-0.1827image
ENSG00000166441.11,RPL27ATGCTGSVA_HALLMARK_IL2_STAT5_SIGNALINGEAG6.6740e-040.2852image
chr11:8686238-8687804:+TGCTGSVA_HALLMARK_IL2_STAT5_SIGNALINGEER6.6740e-040.2852image
chr11:8686238-8687804:+THCAGSVA_HALLMARK_G2M_CHECKPOINTEER1.4939e-07-0.2314image
ENSG00000166441.11,RPL27ATHCAGSVA_HALLMARK_G2M_CHECKPOINTEAG1.4939e-07-0.2314image
chr11:8686238-8687804:+THYMGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEER2.2124e-050.3798image
ENSG00000166441.11,RPL27ATHYMGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEAG2.2124e-050.3798image
chr11:8686238-8687804:+UCECGSVA_HALLMARK_PROTEIN_SECRETIONEER2.3433e-04-0.2770image
ENSG00000166441.11,RPL27AUCECGSVA_HALLMARK_PROTEIN_SECRETIONEAG2.5515e-04-0.2754image
chr11:8686238-8687804:+UCSGSVA_HALLMARK_COAGULATIONEER2.4571e-030.4003image
ENSG00000166441.11,RPL27AUCSGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKBEAG2.4787e-030.4000image
ENSG00000166441.11,RPL27AUVMGSVA_HALLMARK_KRAS_SIGNALING_DNEAG1.7016e-020.2662image
chr11:8686238-8687804:+UVMGSVA_HALLMARK_KRAS_SIGNALING_DNEER1.7016e-020.2662image


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7. Enriched editing regions and drugs for RPL27A


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
ENSG00000166441.11,RPL27AACCElesclomolEAG5.8626e-030.3332image
chr11:8686238-8687804:+ACCElesclomolEER5.8626e-030.3332image
chr11:8686238-8687804:+BRCACCT018159EER8.5450e-03-0.0813image
ENSG00000166441.11,RPL27ABRCACCT018159EAG8.5450e-03-0.0813image
chr11:8686238-8687804:+CESCMidostaurinEER1.6970e-030.1858image
ENSG00000166441.11,RPL27ACESCMidostaurinEAG1.6970e-030.1858image
ENSG00000166441.11,RPL27ACHOLMethotrexateEAG4.9550e-03-0.4775image
chr11:8686238-8687804:+CHOLMethotrexateEER4.9550e-03-0.4775image
ENSG00000166441.11,RPL27ACOADGW843682XEAG3.8936e-050.2480image
chr11:8686238-8687804:+COADGW843682XEER2.5268e-030.1838image
ENSG00000166441.11,RPL27ADLBCGNF.2EAG3.1208e-03-0.4179image
chr11:8686238-8687804:+DLBCGNF.2EER3.1208e-03-0.4179image
ENSG00000166441.11,RPL27AESCAGNF.2EAG1.0717e-02-0.2013image
chr11:8686238-8687804:+ESCAGNF.2EER1.0832e-02-0.2010image
chr11:8686238-8687804:+GBMCamptothecinEER4.5868e-020.1557image
ENSG00000166441.11,RPL27AGBMCamptothecinEAG4.5298e-020.1561image
ENSG00000166441.11,RPL27AHNSCCGP.60474EAG3.4457e-03-0.1334image
chr11:8686238-8687804:+HNSCCGP.60474EER3.4436e-03-0.1334image
ENSG00000166441.11,RPL27AKICHAZD.2281EAG2.9208e-02-0.2749image
chr11:8686238-8687804:+KICHAZD.2281EER2.9208e-02-0.2749image
ENSG00000166441.11,RPL27AKIRCCEP.701EAG1.4764e-030.1632image
chr11:8686238-8687804:+KIRCCEP.701EER1.4764e-030.1632image
chr11:8686238-8687804:+KIRPJW.7.52.1EER1.0299e-030.1948image
ENSG00000166441.11,RPL27AKIRPJW.7.52.1EAG1.0299e-030.1948image
ENSG00000166441.11,RPL27ALAMLAZD6244EAG1.6387e-07-0.4197image
chr11:8686238-8687804:+LAMLAZD6244EER1.6387e-07-0.4197image
chr11:8686238-8687804:+LGGBAY.61.3606EER1.2767e-060.2091image
ENSG00000166441.11,RPL27ALGGBAY.61.3606EAG1.4083e-060.2083image
chr11:8686238-8687804:+LIHCImatinibEER9.9008e-030.1424image
ENSG00000166441.11,RPL27ALIHCImatinibEAG9.9008e-030.1424image
ENSG00000166441.11,RPL27ALUADFH535EAG1.0731e-020.1168image
chr11:8686238-8687804:+LUADFH535EER1.0793e-020.1168image
ENSG00000166441.11,RPL27ALUSCBX.795EAG3.5475e-050.1901image
chr11:8686238-8687804:+LUSCBX.795EER3.5448e-050.1901image
ENSG00000166441.11,RPL27AMESOAZD.0530EAG7.3361e-04-0.3655image
chr11:8686238-8687804:+MESOAZD.0530EER7.3361e-04-0.3655image
chr11:8686238-8687804:+OVEmbelinEER3.6948e-070.2927image
ENSG00000166441.11,RPL27AOVEmbelinEAG3.1789e-070.2943image
ENSG00000166441.11,RPL27APAADFTI.277EAG2.8634e-03-0.2229image
chr11:8686238-8687804:+PAADFTI.277EER2.8634e-03-0.2229image
ENSG00000166441.11,RPL27APCPGAZD7762EAG1.8804e-03-0.2321image
chr11:8686238-8687804:+PCPGAZD7762EER1.8804e-03-0.2321image
ENSG00000166441.11,RPL27APRADDMOGEAG9.4637e-050.1742image
chr11:8686238-8687804:+PRADDMOGEER9.4637e-050.1742image
chr11:8686238-8687804:+SARCGSK.650394EER1.0152e-030.2104image
ENSG00000166441.11,RPL27ASARCGSK.650394EAG1.0152e-030.2104image
ENSG00000166441.11,RPL27ASKCMCGP.082996EAG5.0669e-07-0.2342image
chr11:8686238-8687804:+SKCMCGP.082996EER5.0420e-07-0.2342image
ENSG00000166441.11,RPL27ASTADBAY.61.3606EAG1.6420e-020.1259image
chr11:8686238-8687804:+STADBAY.61.3606EER1.5921e-020.1265image
ENSG00000166441.11,RPL27ATGCTAZ628EAG1.8101e-03-0.2623image
chr11:8686238-8687804:+TGCTAZ628EER1.8101e-03-0.2623image
chr11:8686238-8687804:+THCABryostatin.1EER2.2857e-07-0.2280image
ENSG00000166441.11,RPL27ATHCABryostatin.1EAG2.2857e-07-0.2280image
chr11:8686238-8687804:+THYMBX.795EER1.0342e-050.3936image
ENSG00000166441.11,RPL27ATHYMBX.795EAG1.0342e-050.3936image
chr11:8686238-8687804:+UCECABT.888EER7.5730e-05-0.2971image
ENSG00000166441.11,RPL27AUCECABT.888EAG7.6200e-05-0.2970image
ENSG00000166441.11,RPL27AUCSCisplatinEAG2.2257e-04-0.4781image
chr11:8686238-8687804:+UCSCisplatinEER2.0268e-04-0.4808image
chr11:8686238-8687804:+UVMCGP.60474EER5.8267e-04-0.3762image
ENSG00000166441.11,RPL27AUVMCGP.60474EAG5.8267e-04-0.3762image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType