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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: DCAF16 (ImmuneEditome ID:54876)

1. Gene summary of enriched editing regions for DCAF16

check button Gene summary
Gene informationGene symbol

DCAF16

Gene ID

54876

GeneSynonymsC4orf30
GeneCytomap

4p15.31

GeneTypeprotein-coding
GeneDescriptionDDB1- and CUL4-associated factor 16
GeneModificationdate20230517
UniprotIDQ9NXF7
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr4:17801097-17803305:-ENST00000382247.4ENSG00000163257.9DCAF16UTR3AluSx,AluSz,(A)n,AluYchr4:17801097-17803305:-.alignment


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2. Tumor-specific enriched editing regions for DCAF16


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chr4:17801097-17803305:-BRCAEER1.6448e-06image
ENSG00000163257.9,DCAF16BRCAEAG1.6777e-06image
chr4:17801097-17803305:-COADEER1.1904e-04image
ENSG00000163257.9,DCAF16COADEAG1.1951e-04image
chr4:17801097-17803305:-HNSCEER8.7472e-05image
ENSG00000163257.9,DCAF16HNSCEAG8.7472e-05image
chr4:17801097-17803305:-KIRCEER2.7173e-02image
ENSG00000163257.9,DCAF16KIRCEAG2.7349e-02image
chr4:17801097-17803305:-KIRPEER1.5660e-05image
ENSG00000163257.9,DCAF16KIRPEAG1.5616e-05image
chr4:17801097-17803305:-LIHCEER2.2133e-02image
ENSG00000163257.9,DCAF16LIHCEAG2.2133e-02image
chr4:17801097-17803305:-LUSCEER9.9401e-06image
ENSG00000163257.9,DCAF16LUSCEAG9.9401e-06image
chr4:17801097-17803305:-PRADEER6.5281e-03image
ENSG00000163257.9,DCAF16PRADEAG6.5696e-03image
chr4:17801097-17803305:-STADEER4.2664e-02image
ENSG00000163257.9,DCAF16STADEAG4.3875e-02image
chr4:17801097-17803305:-THCAEER2.0292e-09image
ENSG00000163257.9,DCAF16THCAEAG2.0292e-09image
chr4:17801097-17803305:-UCECEER7.5261e-08image
ENSG00000163257.9,DCAF16UCECEAG7.5261e-08image


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
ENSG00000163257.9,DCAF16ESCAPathEAG2.4421e-032.3815e-020.1890image
chr4:17801097-17803305:-ESCAPathEER2.3634e-032.4664e-020.1878image
ENSG00000163257.9,DCAF16KIRCPathEAG1.4105e-033.3367e-040.1554image
chr4:17801097-17803305:-KIRCPathEER1.3742e-033.3268e-040.1554image


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
chr4:17801097-17803305:-LGGEER1.3858e-034.3189e-042.9231e+04image
ENSG00000163257.9,DCAF16LGGEAG1.3858e-034.3189e-042.9231e+04image

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3. Enriched editing regions and immune related genes for DCAF16


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr4:17801097-17803305:-COADEERENSG00000162545,CAMK2N10.21551.1772e-024.9575e-300.6170imageNAUH;BCCIP;CNBP;CSTF2T;DDX54;DGCR8;EIF4A3;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;LARP4B;LIN28;LIN28A;LIN28B;MBNL2;MOV10;NONO;NOP56;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM47;SF3A3;SLTM;SMNDC1;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TRA2A;U2AF1;U2AF2;UPF1;ZNF184NADendritic_cells_activatedGSVA_HALLMARK_MYC_TARGETS_V2
chr4:17801097-17803305:-COADEERENSG00000181222,POLR2A-0.17964.3151e-022.0529e-210.5327imageNAUH;BCCIP;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHSRP;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM22;RBM27;SAFB2;SBDS;SF3A3;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YWHAG;ZNF184NADendritic_cells_activatedGSVA_HALLMARK_APICAL_SURFACE
chr4:17801097-17803305:-UCECEERENSG00000116350,SRSF4-0.32015.6454e-031.7073e-08-0.4114imageNADAR;AUH;BCCIP;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM22;RBM27;RBM47;SAFB2;SF3A3;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;ZNF184NAGSVA_HALLMARK_MITOTIC_SPINDLE
chr4:17801097-17803305:-UCECEERENSG00000189171,S100A130.25404.0833e-023.0778e-090.4304imageNAUH;BCCIP;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;EIF4A3;EIF4G1;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHSRP;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM22;RBM27;RNF219;SAFB2;SBDS;SF3A3;SLTM;SMNDC1;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;ZNF184S100A13T_cells_CD4_memory_restingGSVA_HALLMARK_MITOTIC_SPINDLE
chr4:17801097-17803305:-UCECEERENSG00000222041,LINC001520.25354.1864e-021.7904e-080.4108imageNADAR;AUH;BCCIP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;LARP4B;LIN28B;MOV10;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RBFOX2;RBM47;SF3A3;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2NAT_cells_CD8GSVA_HALLMARK_PROTEIN_SECRETION
chr4:17801097-17803305:-UVMEERENSG00000142327,RNPEPL10.58016.6126e-051.0246e-070.5562imageNADAR;AUH;BCCIP;CELF2;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHSRP;LIN28;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM27;RNF219;SAFB2;SF3A3;SLTM;SMNDC1;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YWHAG;ZNF184NAT_cells_CD4_memory_restingGSVA_HALLMARK_KRAS_SIGNALING_DN
chr4:17801097-17803305:-UVMEERENSG00000197989,SNHG12-0.57909.0152e-052.3900e-07-0.5427imageNADAR;AUH;BCCIP;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM22;RBM27;RBM47;RNF219;SAFB2;SBDS;SF3A3;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YWHAG;ZNF184NAT_cells_CD4_memory_restingGSVA_HALLMARK_KRAS_SIGNALING_DN
chr4:17801097-17803305:-UVMEERENSG00000039650,PNKP0.54661.0566e-041.0673e-090.6205imageNAUH;BCCIP;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHSRP;LARP4B;LIN28;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM22;RBM27;RNF219;SAFB2;SBDS;SF3A3;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YWHAG;ZNF184NAT_cells_CD4_memory_restingGSVA_HALLMARK_COAGULATION
chr4:17801097-17803305:-UVMEERENSG00000188785,ZNF548-0.56811.1555e-047.8938e-08-0.5603imageNADAR;AUH;BCCIP;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DHX9;EIF4A3;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM22;SAFB2;SF3A3;SLTM;SMNDC1;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TNRC6A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;ZNF184NANeutrophilsGSVA_HALLMARK_XENOBIOTIC_METABOLISM
chr4:17801097-17803305:-UVMEERENSG00000265458,RP13-20L14.60.56911.1624e-044.9915e-080.5673imageNDDX3X;EIF4A3;NOP56;SRSF1;SRSF7;U2AF1;U2AF2;UPF1NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_KRAS_SIGNALING_UP

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4. Enriched editing regions and immune related splicing for DCAF16


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr4:17801097-17803305:-
COADEERESENSG00000103121.4chr1680976116:80976179:80981805:80981877:80997313:809973720.23941.3166e-025.7805e-13-0.4186imageNADAR;BCCIP;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM22;RBM27;RBM47;SBDS;SF3A3;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YWHAG;ZNF184NADendritic_cells_activatedGSVA_HALLMARK_PEROXISOME
chr4:17801097-17803305:-
COADEERMEXENSG00000170266.11chr333053490:33053549:33058088:33058269:33068229:33068290:33068819:330689700.21694.8038e-026.4209e-150.4493imageNADAR;AUH;BCCIP;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM22;RBM27;RBM47;RNF219;SAFB2;SBDS;SF3A3;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YWHAG;ZNF184NAEosinophilsGSVA_HALLMARK_HEME_METABOLISM
ENSG00000163257.9,DCAF16
COADEAGESENSG00000103121.4chr1680976116:80976179:80981805:80981877:80997313:809973720.23941.5338e-025.7805e-13-0.4186imageNACIN1;ADAR;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NADendritic_cells_activatedGSVA_HALLMARK_PEROXISOME
chr4:17801097-17803305:-
UVMEERIRENSG00000141258.8chr172362837:2362905:2362988:2363045-0.52841.5825e-049.7026e-07-0.5608imageNADAR;AUH;BCCIP;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;EIF4A3;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM22;RNF219;SAFB2;SF3A3;SLTM;SMNDC1;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;ZNF184NAMacrophages_M0GSVA_HALLMARK_XENOBIOTIC_METABOLISM
chr4:17801097-17803305:-
UVMEERIRENSG00000156976.10chr3186784202:186784513:186785882:1867859130.42652.0559e-022.5006e-040.4034imageNADAR;AUH;BCCIP;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM22;RBM27;RBM47;RNF219;SAFB2;SBDS;SF3A3;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YWHAG;ZNF184NAB_cells_naiveGSVA_HALLMARK_KRAS_SIGNALING_UP
chr4:17801097-17803305:-
UVMEERA3ENSG00000162298.12chr1165133469:65133548:65133159:65133252:65133159:651332690.41882.9659e-042.9356e-060.5013imageNAUH;BCCIP;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;EIF4A3;EIF4G1;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;RANGAP1;RBFOX2;RBM22;RBM27;RBM47;RNF219;SAFB2;SF3A3;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YWHAG;ZNF184SYVN1B_cells_naiveGSVA_HALLMARK_KRAS_SIGNALING_UP
chr4:17801097-17803305:-
UVMEERA3ENSG00000171552.8chr2031723863:31723989:31721654:31722330:31721654:317223480.42366.6290e-031.8661e-070.6135imageNADAR;AUH;BCCIP;CELF2;CNBP;CSTF2T;DDX3X;DDX54;DGCR8;DHX9;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPC;HNRNPK;HNRNPM;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;MBNL2;MOV10;MSI2;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM22;RBM27;RBM47;SF3A3;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1BCL2L1GSVA_HALLMARK_XENOBIOTIC_METABOLISM
chr4:17801097-17803305:-
UVMEERIRENSG00000135596.13chr6109451599:109451700:109452245:109452401-0.47817.7291e-031.6683e-04-0.4137imageNADAR;AUH;BCCIP;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;EIF4A3;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM22;RBM27;RBM47;SAFB2;SF3A3;SLTM;SMNDC1;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;ZNF184NAMacrophages_M2GSVA_HALLMARK_KRAS_SIGNALING_DN
chr4:17801097-17803305:-
UVMEERA3ENSG00000109065.7chr1774771959:74771977:74771727:74771844:74771727:74771858-0.35901.0912e-029.7727e-06-0.4749imageNADAR;AUH;BCCIP;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM22;RBM27;RNF219;SAFB2;SF3A3;SLTM;SMNDC1;SND1;SRSF1;SRSF7;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YWHAG;ZNF184NAT_cells_CD8GSVA_HALLMARK_XENOBIOTIC_METABOLISM
chr4:17801097-17803305:-
UVMEERIRENSG00000183889.8chr1616327735:16328198:16328650:16328807-0.40524.7095e-021.2371e-04-0.4288imageNADAR;ELAVL1;FUS;HNRNPA1;HNRNPC;IGF2BP2;IGF2BP3;MBNL2;NUMA1;SRSF1;TAF15;TARDBP;TIA1;TROVE2;U2AF2NAT_cells_CD4_memory_restingGSVA_HALLMARK_ESTROGEN_RESPONSE_EARLY

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5. Enriched editing regions and immune infiltration for DCAF16


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chr4:17801097-17803305:-BLCAEERMacrophages_M12.3696e-040.1817image
ENSG00000163257.9,DCAF16BLCAEAGMacrophages_M12.3701e-040.1817image
chr4:17801097-17803305:-BRCAEERT_cells_CD4_memory_activated4.6254e-060.1386image
ENSG00000163257.9,DCAF16BRCAEAGT_cells_CD4_memory_activated4.2981e-060.1391image
chr4:17801097-17803305:-CESCEERMonocytes4.6232e-030.1623image
ENSG00000163257.9,DCAF16CESCEAGMonocytes4.6232e-030.1623image
chr4:17801097-17803305:-COADEERDendritic_cells_activated7.9912e-070.2935image
ENSG00000163257.9,DCAF16COADEAGDendritic_cells_activated7.9912e-070.2935image
chr4:17801097-17803305:-DLBCEERMast_cells_resting8.3766e-030.3764image
ENSG00000163257.9,DCAF16DLBCEAGMast_cells_resting8.3766e-030.3764image
chr4:17801097-17803305:-ESCAEERMonocytes1.7163e-02-0.1876image
ENSG00000163257.9,DCAF16ESCAEAGNK_cells_activated1.5951e-020.1897image
chr4:17801097-17803305:-GBMEERT_cells_gamma_delta1.5858e-020.1870image
ENSG00000163257.9,DCAF16GBMEAGT_cells_gamma_delta1.5858e-020.1870image
chr4:17801097-17803305:-HNSCEERT_cells_regulatory_(Tregs)8.5637e-03-0.1176image
ENSG00000163257.9,DCAF16HNSCEAGT_cells_regulatory_(Tregs)8.5637e-03-0.1176image
chr4:17801097-17803305:-KICHEERNeutrophils2.9301e-02-0.2705image
ENSG00000163257.9,DCAF16KICHEAGNeutrophils2.9301e-02-0.2705image
chr4:17801097-17803305:-KIRCEERT_cells_regulatory_(Tregs)1.6051e-020.1230image
ENSG00000163257.9,DCAF16KIRCEAGT_cells_regulatory_(Tregs)1.6051e-020.1230image
chr4:17801097-17803305:-LAMLEERT_cells_CD4_memory_activated1.5661e-02-0.2100image
ENSG00000163257.9,DCAF16LAMLEAGT_cells_CD4_memory_activated1.6368e-02-0.2086image
chr4:17801097-17803305:-LGGEERMacrophages_M12.1343e-050.1837image
ENSG00000163257.9,DCAF16LGGEAGMacrophages_M12.1352e-050.1836image
chr4:17801097-17803305:-LIHCEERMonocytes8.4535e-030.1488image
ENSG00000163257.9,DCAF16LIHCEAGMonocytes8.4535e-030.1488image
chr4:17801097-17803305:-LUADEERT_cells_CD4_naive9.6231e-040.1459image
ENSG00000163257.9,DCAF16LUADEAGT_cells_CD4_naive9.6231e-040.1459image
chr4:17801097-17803305:-LUSCEERT_cells_CD4_memory_activated4.6048e-050.1819image
ENSG00000163257.9,DCAF16LUSCEAGT_cells_CD4_memory_activated4.6048e-050.1819image
chr4:17801097-17803305:-OVEERB_cells_memory5.3436e-030.1632image
ENSG00000163257.9,DCAF16OVEAGB_cells_memory5.6108e-030.1623image
chr4:17801097-17803305:-PCPGEERT_cells_regulatory_(Tregs)4.0770e-020.1514image
ENSG00000163257.9,DCAF16PCPGEAGT_cells_regulatory_(Tregs)4.0770e-020.1514image
chr4:17801097-17803305:-PRADEERMast_cells_activated1.9531e-03-0.1383image
ENSG00000163257.9,DCAF16PRADEAGMast_cells_activated1.9650e-03-0.1382image
chr4:17801097-17803305:-READEERT_cells_CD4_memory_activated7.9998e-03-0.2706image
ENSG00000163257.9,DCAF16READEAGT_cells_CD4_memory_activated7.9998e-03-0.2706image
chr4:17801097-17803305:-SARCEERMacrophages_M21.8645e-020.1472image
ENSG00000163257.9,DCAF16SARCEAGMacrophages_M21.8645e-020.1472image
chr4:17801097-17803305:-SKCMEERT_cells_CD81.8682e-070.2381image
ENSG00000163257.9,DCAF16SKCMEAGT_cells_CD81.8682e-070.2381image
chr4:17801097-17803305:-STADEEREosinophils2.7820e-05-0.2157image
ENSG00000163257.9,DCAF16STADEAGEosinophils2.7595e-05-0.2158image
chr4:17801097-17803305:-TGCTEERMacrophages_M24.1594e-09-0.4516image
ENSG00000163257.9,DCAF16TGCTEAGMacrophages_M24.1594e-09-0.4516image
chr4:17801097-17803305:-THCAEERT_cells_regulatory_(Tregs)1.0587e-030.1457image
ENSG00000163257.9,DCAF16THCAEAGT_cells_regulatory_(Tregs)1.0587e-030.1457image
chr4:17801097-17803305:-THYMEERMacrophages_M17.4723e-050.3578image
ENSG00000163257.9,DCAF16THYMEAGMacrophages_M17.4723e-050.3578image
chr4:17801097-17803305:-UCSEERMonocytes1.6488e-02-0.3192image
ENSG00000163257.9,DCAF16UCSEAGMonocytes1.6488e-02-0.3192image
chr4:17801097-17803305:-UVMEERT_cells_CD4_memory_resting4.0265e-03-0.3201image
ENSG00000163257.9,DCAF16UVMEAGT_cells_CD4_memory_resting4.0265e-03-0.3201image


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6. Enriched editing regions and immune gene sets for DCAF16


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot
chr4:17801097-17803305:-COADEER2.9630e-02-0.13178.1329e-03-0.15994.5407e-03-0.17134.6834e-02-0.1204image
ENSG00000163257.9,DCAF16COADEAG2.9630e-02-0.13178.1329e-03-0.15994.5407e-03-0.17134.6834e-02-0.1204image
chr4:17801097-17803305:-PCPGEER3.9806e-02-0.15214.1186e-02-0.15114.0787e-03-0.21144.6838e-02-0.1472image
ENSG00000163257.9,DCAF16PCPGEAG3.9806e-02-0.15214.1186e-02-0.15114.0787e-03-0.21144.6838e-02-0.1472image


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
ENSG00000163257.9,DCAF16ACCGSVA_HALLMARK_KRAS_SIGNALING_DNEAG3.7756e-02-0.2357image
chr4:17801097-17803305:-ACCGSVA_HALLMARK_KRAS_SIGNALING_DNEER3.7756e-02-0.2357image
chr4:17801097-17803305:-BLCAGSVA_HALLMARK_GLYCOLYSISEER1.4133e-040.1880image
ENSG00000163257.9,DCAF16BLCAGSVA_HALLMARK_GLYCOLYSISEAG1.4054e-040.1881image
ENSG00000163257.9,DCAF16BRCAGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG3.3147e-140.2276image
chr4:17801097-17803305:-BRCAGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER5.0737e-140.2260image
chr4:17801097-17803305:-CESCGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER1.9625e-05-0.2426image
ENSG00000163257.9,DCAF16CESCGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG1.9625e-05-0.2426image
ENSG00000163257.9,DCAF16CHOLGSVA_HALLMARK_IL2_STAT5_SIGNALINGEAG1.2592e-02-0.4175image
chr4:17801097-17803305:-CHOLGSVA_HALLMARK_IL2_STAT5_SIGNALINGEER1.2592e-02-0.4175image
chr4:17801097-17803305:-COADGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER8.4567e-03-0.1591image
ENSG00000163257.9,DCAF16COADGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG8.4567e-03-0.1591image
chr4:17801097-17803305:-DLBCGSVA_HALLMARK_HYPOXIAEER3.3509e-030.4151image
ENSG00000163257.9,DCAF16DLBCGSVA_HALLMARK_HYPOXIAEAG3.3509e-030.4151image
chr4:17801097-17803305:-ESCAGSVA_HALLMARK_ESTROGEN_RESPONSE_EARLYEER2.0882e-03-0.2408image
ENSG00000163257.9,DCAF16ESCAGSVA_HALLMARK_ESTROGEN_RESPONSE_EARLYEAG2.0485e-03-0.2413image
ENSG00000163257.9,DCAF16GBMGSVA_HALLMARK_HEDGEHOG_SIGNALINGEAG4.5214e-04-0.2692image
chr4:17801097-17803305:-GBMGSVA_HALLMARK_HEDGEHOG_SIGNALINGEER4.5214e-04-0.2692image
chr4:17801097-17803305:-HNSCGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER5.5932e-04-0.1539image
ENSG00000163257.9,DCAF16HNSCGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG5.5932e-04-0.1539image
ENSG00000163257.9,DCAF16KICHGSVA_HALLMARK_SPERMATOGENESISEAG8.0119e-030.3262image
chr4:17801097-17803305:-KICHGSVA_HALLMARK_SPERMATOGENESISEER8.0119e-030.3262image
ENSG00000163257.9,DCAF16KIRCGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG6.6484e-05-0.2024image
chr4:17801097-17803305:-KIRCGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER6.6484e-05-0.2024image
ENSG00000163257.9,DCAF16KIRPGSVA_HALLMARK_XENOBIOTIC_METABOLISMEAG5.1188e-060.2673image
chr4:17801097-17803305:-KIRPGSVA_HALLMARK_XENOBIOTIC_METABOLISMEER4.9668e-060.2676image
ENSG00000163257.9,DCAF16LAMLGSVA_HALLMARK_MYC_TARGETS_V1EAG2.2315e-030.2639image
chr4:17801097-17803305:-LAMLGSVA_HALLMARK_MYC_TARGETS_V1EER1.8545e-030.2685image
ENSG00000163257.9,DCAF16LGGGSVA_HALLMARK_MYOGENESISEAG2.5188e-150.3348image
chr4:17801097-17803305:-LGGGSVA_HALLMARK_MYOGENESISEER2.5052e-150.3349image
ENSG00000163257.9,DCAF16LIHCGSVA_HALLMARK_PEROXISOMEEAG8.6122e-080.2974image
chr4:17801097-17803305:-LIHCGSVA_HALLMARK_PEROXISOMEEER8.6122e-080.2974image
ENSG00000163257.9,DCAF16LUADGSVA_HALLMARK_APOPTOSISEAG1.3562e-070.2310image
chr4:17801097-17803305:-LUADGSVA_HALLMARK_APOPTOSISEER1.3562e-070.2310image
ENSG00000163257.9,DCAF16LUSCGSVA_HALLMARK_TGF_BETA_SIGNALINGEAG1.0546e-02-0.1147image
chr4:17801097-17803305:-LUSCGSVA_HALLMARK_TGF_BETA_SIGNALINGEER1.0546e-02-0.1147image
chr4:17801097-17803305:-MESOGSVA_HALLMARK_PROTEIN_SECRETIONEER2.3576e-020.2514image
ENSG00000163257.9,DCAF16MESOGSVA_HALLMARK_PROTEIN_SECRETIONEAG2.3576e-020.2514image
ENSG00000163257.9,DCAF16OVGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEAG1.6802e-090.3445image
chr4:17801097-17803305:-OVGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEER1.6921e-090.3444image
chr4:17801097-17803305:-PAADGSVA_HALLMARK_HEDGEHOG_SIGNALINGEER2.1626e-04-0.2739image
ENSG00000163257.9,DCAF16PAADGSVA_HALLMARK_HEDGEHOG_SIGNALINGEAG2.1626e-04-0.2739image
ENSG00000163257.9,DCAF16PCPGGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG1.0950e-03-0.2395image
chr4:17801097-17803305:-PCPGGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER1.0950e-03-0.2395image
chr4:17801097-17803305:-PRADGSVA_HALLMARK_MYC_TARGETS_V1EER4.8425e-050.1808image
ENSG00000163257.9,DCAF16PRADGSVA_HALLMARK_MYC_TARGETS_V1EAG4.7147e-050.1811image
chr4:17801097-17803305:-READGSVA_HALLMARK_MITOTIC_SPINDLEEER4.2676e-03-0.2907image
ENSG00000163257.9,DCAF16READGSVA_HALLMARK_MITOTIC_SPINDLEEAG4.2676e-03-0.2907image
chr4:17801097-17803305:-SARCGSVA_HALLMARK_FATTY_ACID_METABOLISMEER8.5142e-040.2076image
ENSG00000163257.9,DCAF16SARCGSVA_HALLMARK_FATTY_ACID_METABOLISMEAG8.5142e-040.2076image
chr4:17801097-17803305:-SKCMGSVA_HALLMARK_ANDROGEN_RESPONSEEER1.9152e-07-0.2379image
ENSG00000163257.9,DCAF16SKCMGSVA_HALLMARK_ANDROGEN_RESPONSEEAG1.9152e-07-0.2379image
chr4:17801097-17803305:-STADGSVA_HALLMARK_MYC_TARGETS_V2EER1.7422e-050.2210image
ENSG00000163257.9,DCAF16STADGSVA_HALLMARK_MYC_TARGETS_V2EAG1.5283e-050.2224image
chr4:17801097-17803305:-TGCTGSVA_HALLMARK_TGF_BETA_SIGNALINGEER1.2810e-05-0.3436image
ENSG00000163257.9,DCAF16TGCTGSVA_HALLMARK_TGF_BETA_SIGNALINGEAG1.2810e-05-0.3436image
chr4:17801097-17803305:-THCAGSVA_HALLMARK_MYC_TARGETS_V2EER5.8947e-050.1783image
ENSG00000163257.9,DCAF16THCAGSVA_HALLMARK_MYC_TARGETS_V2EAG5.8947e-050.1783image
chr4:17801097-17803305:-THYMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.7803e-050.3854image
ENSG00000163257.9,DCAF16THYMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG1.7803e-050.3854image
chr4:17801097-17803305:-UCECGSVA_HALLMARK_MITOTIC_SPINDLEEER3.1942e-03-0.2223image
ENSG00000163257.9,DCAF16UCECGSVA_HALLMARK_MITOTIC_SPINDLEEAG3.1942e-03-0.2223image
ENSG00000163257.9,DCAF16UCSGSVA_HALLMARK_MYOGENESISEAG1.6747e-03-0.4105image
chr4:17801097-17803305:-UCSGSVA_HALLMARK_MYOGENESISEER1.6747e-03-0.4105image
chr4:17801097-17803305:-UVMGSVA_HALLMARK_XENOBIOTIC_METABOLISMEER9.9238e-060.4746image
ENSG00000163257.9,DCAF16UVMGSVA_HALLMARK_XENOBIOTIC_METABOLISMEAG9.9238e-060.4746image


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7. Enriched editing regions and drugs for DCAF16


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
ENSG00000163257.9,DCAF16ACCGDC0941EAG5.5317e-040.3822image
chr4:17801097-17803305:-ACCGDC0941EER5.5317e-040.3822image
chr4:17801097-17803305:-BLCAEHT.1864EER1.0179e-050.2174image
ENSG00000163257.9,DCAF16BLCAEHT.1864EAG1.0131e-050.2174image
ENSG00000163257.9,DCAF16BRCACCT007093EAG7.1081e-130.2157image
chr4:17801097-17803305:-BRCACCT007093EER9.6888e-130.2144image
chr4:17801097-17803305:-CESCDasatinibEER2.0168e-06-0.2695image
ENSG00000163257.9,DCAF16CESCDasatinibEAG2.0168e-06-0.2695image
ENSG00000163257.9,DCAF16CHOLAZD7762EAG8.0094e-030.4410image
chr4:17801097-17803305:-CHOLAZD7762EER8.0094e-030.4410image
chr4:17801097-17803305:-COADGW843682XEER6.7905e-030.1635image
ENSG00000163257.9,DCAF16COADGW843682XEAG6.7905e-030.1635image
chr4:17801097-17803305:-DLBCEtoposideEER7.5700e-030.3809image
ENSG00000163257.9,DCAF16DLBCEtoposideEAG7.5700e-030.3809image
chr4:17801097-17803305:-ESCACamptothecinEER2.7517e-03-0.2345image
ENSG00000163257.9,DCAF16ESCACamptothecinEAG2.5337e-03-0.2364image
ENSG00000163257.9,DCAF16GBMJNK.Inhibitor.VIIIEAG1.2217e-050.3323image
chr4:17801097-17803305:-GBMJNK.Inhibitor.VIIIEER1.2217e-050.3323image
chr4:17801097-17803305:-HNSCMetforminEER5.2911e-06-0.2022image
ENSG00000163257.9,DCAF16HNSCMetforminEAG5.2911e-06-0.2022image
ENSG00000163257.9,DCAF16KICHCGP.082996EAG2.2346e-030.3727image
chr4:17801097-17803305:-KICHCGP.082996EER2.2346e-030.3727image
ENSG00000163257.9,DCAF16KIRCCI.1040EAG3.5346e-06-0.2344image
chr4:17801097-17803305:-KIRCCI.1040EER3.5346e-06-0.2344image
ENSG00000163257.9,DCAF16KIRPGSK.650394EAG5.8574e-080.3155image
chr4:17801097-17803305:-KIRPGSK.650394EER5.9869e-080.3153image
ENSG00000163257.9,DCAF16LAMLLFM.A13EAG6.6742e-030.2350image
chr4:17801097-17803305:-LAMLLFM.A13EER7.7773e-030.2307image
ENSG00000163257.9,DCAF16LGGMG.132EAG1.8313e-16-0.3475image
chr4:17801097-17803305:-LGGMG.132EER1.8343e-16-0.3475image
ENSG00000163257.9,DCAF16LIHCBMS.754807EAG1.1644e-090.3368image
chr4:17801097-17803305:-LIHCBMS.754807EER1.1644e-090.3368image
ENSG00000163257.9,DCAF16LUADBMS.509744EAG2.9856e-06-0.2054image
chr4:17801097-17803305:-LUADBMS.509744EER2.9856e-06-0.2054image
ENSG00000163257.9,DCAF16LUSCAP.24534EAG2.9546e-050.1864image
chr4:17801097-17803305:-LUSCAP.24534EER2.9546e-050.1864image
chr4:17801097-17803305:-MESOCEP.701EER1.7462e-030.3426image
ENSG00000163257.9,DCAF16MESOCEP.701EAG1.7462e-030.3426image
ENSG00000163257.9,DCAF16OVEmbelinEAG8.1417e-120.3873image
chr4:17801097-17803305:-OVEmbelinEER8.6660e-120.3869image
chr4:17801097-17803305:-PAADDMOGEER4.6992e-060.3410image
ENSG00000163257.9,DCAF16PAADDMOGEAG4.6992e-060.3410image
ENSG00000163257.9,DCAF16PCPGAxitinibEAG4.1657e-030.2109image
chr4:17801097-17803305:-PCPGAxitinibEER4.1657e-030.2109image
chr4:17801097-17803305:-PRADGDC0941EER1.6933e-060.2124image
ENSG00000163257.9,DCAF16PRADGDC0941EAG1.7879e-060.2119image
chr4:17801097-17803305:-READA.770041EER1.3791e-08-0.5447image
ENSG00000163257.9,DCAF16READA.770041EAG1.3791e-08-0.5447image
chr4:17801097-17803305:-SARCFTI.277EER3.5031e-040.2222image
ENSG00000163257.9,DCAF16SARCFTI.277EAG3.5031e-040.2222image
chr4:17801097-17803305:-SKCMGNF.2EER2.2523e-12-0.3168image
ENSG00000163257.9,DCAF16SKCMGNF.2EAG2.2523e-12-0.3168image
chr4:17801097-17803305:-STADBMS.708163EER1.8100e-060.2449image
ENSG00000163257.9,DCAF16STADBMS.708163EAG1.5656e-060.2463image
chr4:17801097-17803305:-TGCTBMS.754807EER3.8229e-060.3626image
ENSG00000163257.9,DCAF16TGCTBMS.754807EAG3.8229e-060.3626image
chr4:17801097-17803305:-THCAEmbelinEER2.4548e-070.2279image
ENSG00000163257.9,DCAF16THCAEmbelinEAG2.4548e-070.2279image
chr4:17801097-17803305:-THYMBX.795EER1.6664e-060.4261image
ENSG00000163257.9,DCAF16THYMBX.795EAG1.6664e-060.4261image
chr4:17801097-17803305:-UCECA.770041EER3.3552e-07-0.3753image
ENSG00000163257.9,DCAF16UCECA.770041EAG3.3552e-07-0.3753image
ENSG00000163257.9,DCAF16UCSCCT007093EAG1.5061e-040.4852image
chr4:17801097-17803305:-UCSCCT007093EER1.5061e-040.4852image
chr4:17801097-17803305:-UVMAG.014699EER4.5845e-040.3850image
ENSG00000163257.9,DCAF16UVMAG.014699EAG4.5845e-040.3850image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType