CAeditome Logo

Home

Download

Statistics

Landscape

Help

Contact
Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: MBD3 (ImmuneEditome ID:53615)

1. Gene summary of enriched editing regions for MBD3

check button Gene summary
Gene informationGene symbol

MBD3

Gene ID

53615

GeneSynonyms-
GeneCytomap

19p13.3

GeneTypeprotein-coding
GeneDescriptionmethyl-CpG-binding domain protein 3
GeneModificationdate20230517
UniprotIDO95983;K7EIE8;A0A087WZ12;A0A0A0MTS6;A0A087WT34;A0A087X1H1
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr19:1573809-1574239:-ENST00000156825.4ENSG00000071655.16MBD3UTR3AluSq2chr19:1573809-1574239:-.alignment
chr19:1586549-1590644:-ENST00000156825.4ENSG00000071655.16MBD3intronicAluSx1,AluSq,L1MB7,AluSx3,AluYh3,AluJb,AluJr4,AluJr,L1MB8,AluSq2chr19:1586549-1590644:-.alignment
chr19:1586549-1590644:-ENST00000434436.6ENSG00000071655.16MBD3intronicAluSx1,AluSq,L1MB7,AluSx3,AluYh3,AluJb,AluJr4,AluJr,L1MB8,AluSq2chr19:1586549-1590644:-.alignment
chr19:1586549-1590644:-ENST00000585967.4ENSG00000071655.16MBD3intronicAluSx1,AluSq,L1MB7,AluSx3,AluYh3,AluJb,AluJr4,AluJr,L1MB8,AluSq2chr19:1586549-1590644:-.alignment
chr19:1586549-1590644:-ENST00000592965.2ENSG00000071655.16MBD3intronicAluSx1,AluSq,L1MB7,AluSx3,AluYh3,AluJb,AluJr4,AluJr,L1MB8,AluSq2chr19:1586549-1590644:-.alignment


Top

2. Tumor-specific enriched editing regions for MBD3


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chr19:1586549-1590644:-BRCAEER4.3176e-02image
ENSG00000071655.16,MBD3BRCAEAG3.1758e-02image


Top

check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
ENSG00000071655.16,MBD3CESCCliEAG2.7558e-022.6064e-03-0.2640image
chr19:1586549-1590644:-CESCCliEER1.9707e-021.8205e-03-0.2751image
chr19:1586549-1590644:-KIRCPathEER1.2428e-031.2031e-030.2141image
ENSG00000071655.16,MBD3KIRCPathEAG1.2500e-031.5376e-030.2091image
ENSG00000071655.16,MBD3LUSCPathEAG3.9749e-029.8938e-030.1531image
chr19:1586549-1590644:-LUSCPathEER3.5153e-028.8480e-030.1554image


Top

check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
chr19:1586549-1590644:-KIRCEER2.3933e-023.5136e-032.4448e+02image

Top

3. Enriched editing regions and immune related genes for MBD3


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr19:1586549-1590644:-ESCAEERENSG00000256745,RP11-680H20.10.38796.7066e-043.9400e-080.4212imageNNNAGSVA_HALLMARK_MITOTIC_SPINDLE
chr19:1586549-1590644:-ESCAEERENSG00000132963,POMP0.34783.7343e-036.7667e-090.4421imageNAUH;CNBP;CSTF2T;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FTO;HNRNPA1;HNRNPC;HNRNPK;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHDRBS2;KHDRBS3;LARP7;LIN28;LIN28A;LIN28B;MOV10;MSI1;NOP56;NOP58;PTBP1;QKI;RBFOX2;RBM10;RBM22;RNF219;SLBP;SMNDC1;SND1;SRSF1;TAF15;TARDBP;TROVE2;U2AF2;UPF1;ZC3H7B;AIFM1;DDX3X;ELAVL3;FUS;FXR1;GNL3;GTF2F1;HNRNPL;NONO;NPM1;NUMA1;PCBP2;RBM27;SLTM;TIA1;TNRC6A;U2AF1POMPMacrophages_M1GSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr19:1586549-1590644:-ESCAEERENSG00000135211,TMEM600.30711.5911e-021.1424e-070.4079imageNCNBP;CSTF2T;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;FBL;FMR1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS2;LIN28;LIN28A;LIN28B;MOV10;NOP58;PTBP1;RBFOX2;SMNDC1;SND1;SRSF1;TAF15;TROVE2;U2AF2;UPF1;DDX3X;ELAVL3;FUS;FXR1;GNL3;GTF2F1;NUMA1;PCBP2;TIA1;TNRC6A;U2AF1;YTHDF1NAT_cells_gamma_deltaGSVA_HALLMARK_DNA_REPAIR
chr19:1586549-1590644:-ESCAEERENSG00000101608,MYL12A0.29722.1065e-022.1917e-120.5227imageNAUH;CNBP;CSTF2T;DDX42;DDX54;DGCR8;DICER1;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;LARP7;LIN28;LIN28A;LIN28B;MOV10;MSI1;NOP56;NOP58;PTBP1;QKI;RBFOX2;RBM22;RNF219;SBDS;SLBP;SMNDC1;SND1;SRSF1;TAF15;TARDBP;TROVE2;U2AF2;UPF1;ZC3H7B;AIFM1;DDX3X;FUS;FXR1;GNL3;GTF2F1;HNRNPL;NONO;NPM1;NUMA1;PCBP2;RBM27;SLTM;TIA1;TNRC6A;U2AF1;YTHDF1NAT_cells_CD8GSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr19:1586549-1590644:-ESCAEERENSG00000241511,RPS15AP240.29372.3503e-026.3556e-090.4428imageNNNAT_cells_CD8GSVA_HALLMARK_PROTEIN_SECRETION
chr19:1586549-1590644:-ESCAEERENSG00000256745,RP11-680H20.10.38796.7066e-043.9400e-080.4212imageNNNAGSVA_HALLMARK_MITOTIC_SPINDLE
chr19:1586549-1590644:-ESCAEERENSG00000132963,POMP0.34783.7343e-036.7667e-090.4421imageNAUH;CNBP;CSTF2T;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FTO;HNRNPA1;HNRNPC;HNRNPK;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHDRBS2;KHDRBS3;LARP7;LIN28;LIN28A;LIN28B;MOV10;MSI1;NOP56;NOP58;PTBP1;QKI;RBFOX2;RBM10;RBM22;RNF219;SLBP;SMNDC1;SND1;SRSF1;TAF15;TARDBP;TROVE2;U2AF2;UPF1;ZC3H7B;AIFM1;DDX3X;ELAVL3;FUS;FXR1;GNL3;GTF2F1;HNRNPL;NONO;NPM1;NUMA1;PCBP2;RBM27;SLTM;TIA1;TNRC6A;U2AF1POMPMacrophages_M1GSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr19:1586549-1590644:-ESCAEERENSG00000135211,TMEM600.30711.5911e-021.1424e-070.4079imageNCNBP;CSTF2T;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;FBL;FMR1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS2;LIN28;LIN28A;LIN28B;MOV10;NOP58;PTBP1;RBFOX2;SMNDC1;SND1;SRSF1;TAF15;TROVE2;U2AF2;UPF1;DDX3X;ELAVL3;FUS;FXR1;GNL3;GTF2F1;NUMA1;PCBP2;TIA1;TNRC6A;U2AF1;YTHDF1NAT_cells_gamma_deltaGSVA_HALLMARK_DNA_REPAIR
chr19:1586549-1590644:-ESCAEERENSG00000101608,MYL12A0.29722.1065e-022.1917e-120.5227imageNAUH;CNBP;CSTF2T;DDX42;DDX54;DGCR8;DICER1;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;LARP7;LIN28;LIN28A;LIN28B;MOV10;MSI1;NOP56;NOP58;PTBP1;QKI;RBFOX2;RBM22;RNF219;SBDS;SLBP;SMNDC1;SND1;SRSF1;TAF15;TARDBP;TROVE2;U2AF2;UPF1;ZC3H7B;AIFM1;DDX3X;FUS;FXR1;GNL3;GTF2F1;HNRNPL;NONO;NPM1;NUMA1;PCBP2;RBM27;SLTM;TIA1;TNRC6A;U2AF1;YTHDF1NAT_cells_CD8GSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr19:1586549-1590644:-ESCAEERENSG00000241511,RPS15AP240.29372.3503e-026.3556e-090.4428imageNNNAT_cells_CD8GSVA_HALLMARK_PROTEIN_SECRETION
chr19:1586549-1590644:-ESCAEERENSG00000256745,RP11-680H20.10.38796.7066e-043.9400e-080.4212imageNNNAGSVA_HALLMARK_MITOTIC_SPINDLE
chr19:1586549-1590644:-ESCAEERENSG00000132963,POMP0.34783.7343e-036.7667e-090.4421imageNAUH;CNBP;CSTF2T;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FTO;HNRNPA1;HNRNPC;HNRNPK;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHDRBS2;KHDRBS3;LARP7;LIN28;LIN28A;LIN28B;MOV10;MSI1;NOP56;NOP58;PTBP1;QKI;RBFOX2;RBM10;RBM22;RNF219;SLBP;SMNDC1;SND1;SRSF1;TAF15;TARDBP;TROVE2;U2AF2;UPF1;ZC3H7B;AIFM1;DDX3X;ELAVL3;FUS;FXR1;GNL3;GTF2F1;HNRNPL;NONO;NPM1;NUMA1;PCBP2;RBM27;SLTM;TIA1;TNRC6A;U2AF1POMPMacrophages_M1GSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr19:1586549-1590644:-ESCAEERENSG00000135211,TMEM600.30711.5911e-021.1424e-070.4079imageNCNBP;CSTF2T;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;FBL;FMR1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS2;LIN28;LIN28A;LIN28B;MOV10;NOP58;PTBP1;RBFOX2;SMNDC1;SND1;SRSF1;TAF15;TROVE2;U2AF2;UPF1;DDX3X;ELAVL3;FUS;FXR1;GNL3;GTF2F1;NUMA1;PCBP2;TIA1;TNRC6A;U2AF1;YTHDF1NAT_cells_gamma_deltaGSVA_HALLMARK_DNA_REPAIR
chr19:1586549-1590644:-ESCAEERENSG00000101608,MYL12A0.29722.1065e-022.1917e-120.5227imageNAUH;CNBP;CSTF2T;DDX42;DDX54;DGCR8;DICER1;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;LARP7;LIN28;LIN28A;LIN28B;MOV10;MSI1;NOP56;NOP58;PTBP1;QKI;RBFOX2;RBM22;RNF219;SBDS;SLBP;SMNDC1;SND1;SRSF1;TAF15;TARDBP;TROVE2;U2AF2;UPF1;ZC3H7B;AIFM1;DDX3X;FUS;FXR1;GNL3;GTF2F1;HNRNPL;NONO;NPM1;NUMA1;PCBP2;RBM27;SLTM;TIA1;TNRC6A;U2AF1;YTHDF1NAT_cells_CD8GSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr19:1586549-1590644:-ESCAEERENSG00000241511,RPS15AP240.29372.3503e-026.3556e-090.4428imageNNNAT_cells_CD8GSVA_HALLMARK_PROTEIN_SECRETION
chr19:1586549-1590644:-ESCAEERENSG00000256745,RP11-680H20.10.38796.7066e-043.9400e-080.4212imageNNNAGSVA_HALLMARK_MITOTIC_SPINDLE
chr19:1586549-1590644:-ESCAEERENSG00000132963,POMP0.34783.7343e-036.7667e-090.4421imageNAUH;CNBP;CSTF2T;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FTO;HNRNPA1;HNRNPC;HNRNPK;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHDRBS2;KHDRBS3;LARP7;LIN28;LIN28A;LIN28B;MOV10;MSI1;NOP56;NOP58;PTBP1;QKI;RBFOX2;RBM10;RBM22;RNF219;SLBP;SMNDC1;SND1;SRSF1;TAF15;TARDBP;TROVE2;U2AF2;UPF1;ZC3H7B;AIFM1;DDX3X;ELAVL3;FUS;FXR1;GNL3;GTF2F1;HNRNPL;NONO;NPM1;NUMA1;PCBP2;RBM27;SLTM;TIA1;TNRC6A;U2AF1POMPMacrophages_M1GSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chr19:1586549-1590644:-ESCAEERENSG00000135211,TMEM600.30711.5911e-021.1424e-070.4079imageNCNBP;CSTF2T;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;ELAVL1;FBL;FMR1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS2;LIN28;LIN28A;LIN28B;MOV10;NOP58;PTBP1;RBFOX2;SMNDC1;SND1;SRSF1;TAF15;TROVE2;U2AF2;UPF1;DDX3X;ELAVL3;FUS;FXR1;GNL3;GTF2F1;NUMA1;PCBP2;TIA1;TNRC6A;U2AF1;YTHDF1NAT_cells_gamma_deltaGSVA_HALLMARK_DNA_REPAIR
chr19:1586549-1590644:-ESCAEERENSG00000101608,MYL12A0.29722.1065e-022.1917e-120.5227imageNAUH;CNBP;CSTF2T;DDX42;DDX54;DGCR8;DICER1;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;LARP7;LIN28;LIN28A;LIN28B;MOV10;MSI1;NOP56;NOP58;PTBP1;QKI;RBFOX2;RBM22;RNF219;SBDS;SLBP;SMNDC1;SND1;SRSF1;TAF15;TARDBP;TROVE2;U2AF2;UPF1;ZC3H7B;AIFM1;DDX3X;FUS;FXR1;GNL3;GTF2F1;HNRNPL;NONO;NPM1;NUMA1;PCBP2;RBM27;SLTM;TIA1;TNRC6A;U2AF1;YTHDF1NAT_cells_CD8GSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr19:1586549-1590644:-ESCAEERENSG00000241511,RPS15AP240.29372.3503e-026.3556e-090.4428imageNNNAT_cells_CD8GSVA_HALLMARK_PROTEIN_SECRETION

More results



Top

4. Enriched editing regions and immune related splicing for MBD3


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000071655.16,MBD3
ESCAEAGIRENSG00000185252.13chr2220394114:20394662:20395332:20395418-0.35601.1130e-031.4228e-06-0.4356imageNADAR;AIFM1;BCCIP;BUD13;CAPRIN1;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS3;KHSRP;LARP7;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RNF219;RTCB;SAFB2;SBDS;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDF1;YWHAG;ZNF184NAT_cells_CD4_memory_restingGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
ENSG00000071655.16,MBD3
ESCAEAGIRENSG00000149532.11chr1161419921:61420573:61421191:61421257-0.30691.4314e-022.8240e-06-0.4175imageNACIN1;ADAR;AIFM1;ALKBH5;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YTHDF2;YWHAG;ZC3H7B;ZNF184NAT_cells_CD4_memory_restingGSVA_HALLMARK_HYPOXIA
ENSG00000071655.16,MBD3
ESCAEAGIRENSG00000205531.8chr112952837:2954410:2954526:2954646-0.27982.8067e-022.0010e-06-0.4166imageNACIN1;ADAR;AIFM1;ALKBH5;ALYREF;AUH;BCCIP;BUD13;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YTHDF2;YWHAG;ZC3H7B;ZNF184NAT_cells_CD4_naiveGSVA_HALLMARK_HYPOXIA
chr19:1586549-1590644:-
ESCAEERIRENSG00000185252.13chr2220394114:20394662:20395332:20395418-0.35231.2344e-031.4728e-06-0.4350imageNCNBP;CSTF2T;DDX42;DDX54;DGCR8;DICER1;DKC1;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS3;LARP7;LIN28;LIN28A;LIN28B;MOV10;MSI1;NOP56;NOP58;PTBP1;RBFOX2;RBM10;RBM22;RNF219;SBDS;SLBP;SMNDC1;SND1;SRSF1;TAF15;TARDBP;TROVE2;U2AF2;UPF1;AIFM1;DDX3X;FUS;FXR1;GNL3;GTF2F1;HNRNPL;NONO;NUMA1;PCBP2;RBM27;SLTM;TIA1;TNRC6A;U2AF1;YTHDF1NAT_cells_CD4_memory_restingGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr19:1586549-1590644:-
ESCAEERIRENSG00000205531.8chr112952837:2954410:2954526:2954646-0.27752.5764e-022.1839e-06-0.4152imageNAUH;CBX7;CNBP;CSTF2T;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FTO;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;LARP7;LIN28;LIN28A;LIN28B;MOV10;MSI1;NOP56;NOP58;PTBP1;QKI;RBFOX2;RBM10;RBM22;RNF219;SBDS;SLBP;SMNDC1;SND1;SRSF1;TAF15;TARBP2;TARDBP;TROVE2;U2AF2;UPF1;ZC3H7B;AIFM1;DDX3X;ELAVL3;FUS;FXR1;GNL3;GTF2F1;HNRNPL;NONO;NPM1;NUMA1;PCBP2;RBM27;SLTM;TIA1;TNRC6A;U2AF1;YTHDF1NAT_cells_CD4_naiveGSVA_HALLMARK_HYPOXIA
chr19:1586549-1590644:-
ESCAEERIRENSG00000149532.11chr1161419921:61420573:61421191:61421257-0.30601.2516e-022.6817e-06-0.4184imageNAUH;CBX7;CNBP;CSTF2T;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;ELAVL1;FAM120A;FBL;FMR1;FTO;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;LARP7;LIN28;LIN28A;LIN28B;MOV10;MSI1;NOP56;NOP58;PTBP1;QKI;RBFOX2;RBM10;RBM22;RNF219;SBDS;SLBP;SMNDC1;SND1;SRSF1;TAF15;TARBP2;TARDBP;TROVE2;U2AF2;UPF1;ZC3H7B;AIFM1;DDX3X;ELAVL3;FUS;FXR1;GNL3;GTF2F1;HNRNPL;NONO;NPM1;NUMA1;PCBP2;RBM27;SLTM;TIA1;TNRC6A;U2AF1;YTHDF1NAT_cells_CD4_memory_restingGSVA_HALLMARK_HYPOXIA
ENSG00000071655.16,MBD3
OVEAGIRENSG00000120963.7chr8101202332:101202447:101204649:101204693-0.23388.3651e-036.4825e-08-0.4034imageNADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LARP7;LIN28;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM5;RNF219;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDF1;YWHAG;ZC3H7B;ZNF184NAMacrophages_M1GSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION

More results



Top

5. Enriched editing regions and immune infiltration for MBD3


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chr19:1586549-1590644:-BLCAEERT_cells_CD4_memory_resting2.6416e-030.2479image
ENSG00000071655.16,MBD3BLCAEAGT_cells_CD4_memory_resting2.3451e-030.2500image
chr19:1586549-1590644:-BRCAEERMast_cells_activated3.3342e-02-0.0832image
ENSG00000071655.16,MBD3BRCAEAGMast_cells_activated4.7220e-02-0.0769image
chr19:1586549-1590644:-CESCEERDendritic_cells_activated4.9686e-020.1718image
ENSG00000071655.16,MBD3CESCEAGDendritic_cells_activated3.1904e-020.1862image
chr19:1586549-1590644:-COADEERNeutrophils1.7750e-040.3054image
ENSG00000071655.16,MBD3COADEAGMast_cells_activated1.5856e-030.2592image
chr19:1586549-1590644:-ESCAEERT_cells_CD81.5515e-030.2506image
ENSG00000071655.16,MBD3ESCAEAGT_cells_CD81.3912e-030.2530image
chr19:1586549-1590644:-GBMEERT_cells_follicular_helper9.4854e-03-0.2452image
ENSG00000071655.16,MBD3GBMEAGT_cells_follicular_helper6.9041e-03-0.2550image
ENSG00000071655.16,MBD3KICHEAGPlasma_cells8.5725e-030.4712image
ENSG00000071655.16,MBD3KIRCEAGMacrophages_M24.6028e-02-0.1570image
chr19:1586549-1590644:-KIRPEERDendritic_cells_activated2.1275e-030.2861image
ENSG00000071655.16,MBD3KIRPEAGDendritic_cells_activated1.7805e-030.2895image
chr19:1586549-1590644:-LAMLEERMacrophages_M11.3459e-030.2594image
ENSG00000071655.16,MBD3LAMLEAGMacrophages_M11.0946e-030.2640image
chr19:1586549-1590644:-LGGEERMacrophages_M02.8037e-02-0.1075image
ENSG00000071655.16,MBD3LGGEAGMacrophages_M02.8919e-02-0.1067image
chr19:1586549-1590644:-LIHCEERNK_cells_resting4.7306e-020.2712image
ENSG00000071655.16,MBD3LIHCEAGNK_cells_resting3.7294e-020.2816image
chr19:1586549-1590644:-LUADEERB_cells_naive8.1290e-03-0.1895image
ENSG00000071655.16,MBD3LUADEAGB_cells_naive1.5808e-02-0.1709image
chr19:1586549-1590644:-LUSCEERDendritic_cells_activated1.4939e-02-0.1446image
ENSG00000071655.16,MBD3LUSCEAGDendritic_cells_activated1.8341e-02-0.1401image
chr19:1586549-1590644:-MESOEERB_cells_naive9.9435e-030.4131image
ENSG00000071655.16,MBD3MESOEAGB_cells_naive6.3858e-030.4293image
chr19:1586549-1590644:-OVEERT_cells_regulatory_(Tregs)1.1135e-020.1778image
ENSG00000071655.16,MBD3OVEAGT_cells_regulatory_(Tregs)4.6459e-030.1951image
chr19:1586549-1590644:-PAADEERNK_cells_activated7.6914e-03-0.4430image
ENSG00000071655.16,MBD3PAADEAGNK_cells_activated9.5625e-03-0.4320image
chr19:1586549-1590644:-READEERPlasma_cells1.0244e-020.3435image
ENSG00000071655.16,MBD3READEAGPlasma_cells1.0244e-020.3435image
chr19:1586549-1590644:-SARCEERMonocytes2.2335e-02-0.2272image
ENSG00000071655.16,MBD3SARCEAGPlasma_cells2.8694e-020.2146image
chr19:1586549-1590644:-SKCMEERT_cells_CD81.4921e-040.2344image
ENSG00000071655.16,MBD3SKCMEAGT_cells_CD81.5302e-040.2340image
chr19:1586549-1590644:-STADEERNK_cells_activated2.2597e-020.1253image
ENSG00000071655.16,MBD3STADEAGMacrophages_M02.5976e-02-0.1222image
chr19:1586549-1590644:-TGCTEERB_cells_memory9.4790e-060.5154image
ENSG00000071655.16,MBD3TGCTEAGB_cells_memory1.9061e-040.4375image
chr19:1586549-1590644:-THCAEERNK_cells_resting7.6388e-070.4253image
ENSG00000071655.16,MBD3THCAEAGNK_cells_resting6.7998e-070.4255image
chr19:1586549-1590644:-THYMEERT_cells_follicular_helper2.9663e-02-0.3048image
ENSG00000071655.16,MBD3THYMEAGT_cells_follicular_helper2.5551e-02-0.3066image
ENSG00000071655.16,MBD3UCECEAGT_cells_CD4_memory_resting1.7671e-020.3188image
chr19:1586549-1590644:-UVMEERB_cells_naive4.1610e-020.3807image
ENSG00000071655.16,MBD3UVMEAGB_cells_naive4.1610e-020.3807image


Top

6. Enriched editing regions and immune gene sets for MBD3


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot


Top

check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot


Top

check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
ENSG00000071655.16,MBD3BLCAGSVA_HALLMARK_P53_PATHWAYEAG4.9032e-040.2850image
chr19:1586549-1590644:-BLCAGSVA_HALLMARK_P53_PATHWAYEER6.0901e-040.2813image
chr19:1586549-1590644:-BRCAGSVA_HALLMARK_XENOBIOTIC_METABOLISMEER2.4083e-070.2001image
ENSG00000071655.16,MBD3BRCAGSVA_HALLMARK_XENOBIOTIC_METABOLISMEAG3.1065e-060.1794image
chr19:1586549-1590644:-CESCGSVA_HALLMARK_G2M_CHECKPOINTEER2.4283e-02-0.1968image
ENSG00000071655.16,MBD3CESCGSVA_HALLMARK_G2M_CHECKPOINTEAG3.4598e-02-0.1834image
ENSG00000071655.16,MBD3COADGSVA_HALLMARK_MYC_TARGETS_V2EAG3.1691e-04-0.2939image
chr19:1586549-1590644:-COADGSVA_HALLMARK_MYC_TARGETS_V2EER2.0592e-04-0.3026image
chr19:1586549-1590644:-ESCAGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER3.2447e-020.1708image
ENSG00000071655.16,MBD3ESCAGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG3.0463e-020.1728image
ENSG00000071655.16,MBD3GBMGSVA_HALLMARK_XENOBIOTIC_METABOLISMEAG3.4907e-070.4612image
chr19:1586549-1590644:-GBMGSVA_HALLMARK_XENOBIOTIC_METABOLISMEER1.0233e-070.4794image
ENSG00000071655.16,MBD3HNSCGSVA_HALLMARK_E2F_TARGETSEAG1.3729e-03-0.2254image
chr19:1586549-1590644:-HNSCGSVA_HALLMARK_E2F_TARGETSEER1.2087e-03-0.2279image
ENSG00000071655.16,MBD3KICHGSVA_HALLMARK_APICAL_SURFACEEAG3.7998e-02-0.3806image
ENSG00000071655.16,MBD3KIRCGSVA_HALLMARK_DNA_REPAIREAG6.2144e-040.2661image
chr19:1586549-1590644:-KIRCGSVA_HALLMARK_DNA_REPAIREER3.7840e-040.2760image
chr19:1586549-1590644:-LAMLGSVA_HALLMARK_G2M_CHECKPOINTEER1.1015e-03-0.2639image
ENSG00000071655.16,MBD3LAMLGSVA_HALLMARK_G2M_CHECKPOINTEAG1.8203e-03-0.2526image
chr19:1586549-1590644:-LGGGSVA_HALLMARK_BILE_ACID_METABOLISMEER4.9566e-060.2212image
ENSG00000071655.16,MBD3LGGGSVA_HALLMARK_BILE_ACID_METABOLISMEAG6.0420e-060.2190image
ENSG00000071655.16,MBD3LIHCGSVA_HALLMARK_BILE_ACID_METABOLISMEAG2.6347e-020.2995image
chr19:1586549-1590644:-LIHCGSVA_HALLMARK_NOTCH_SIGNALINGEER1.5174e-02-0.3289image
chr19:1586549-1590644:-LUADGSVA_HALLMARK_APICAL_SURFACEEER2.6179e-020.1596image
ENSG00000071655.16,MBD3LUADGSVA_HALLMARK_APICAL_SURFACEEAG3.4377e-020.1501image
chr19:1586549-1590644:-LUSCGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER1.5451e-020.1438image
ENSG00000071655.16,MBD3LUSCGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG1.0949e-020.1510image
chr19:1586549-1590644:-MESOGSVA_HALLMARK_KRAS_SIGNALING_UPEER1.4145e-020.3949image
ENSG00000071655.16,MBD3MESOGSVA_HALLMARK_KRAS_SIGNALING_UPEAG2.3128e-020.3630image
chr19:1586549-1590644:-OVGSVA_HALLMARK_P53_PATHWAYEER3.0332e-040.2510image
ENSG00000071655.16,MBD3OVGSVA_HALLMARK_P53_PATHWAYEAG3.5484e-040.2448image
chr19:1573809-1574239:-OVGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKBEER2.0224e-03-0.5981image
chr19:1586549-1590644:-PAADGSVA_HALLMARK_ESTROGEN_RESPONSE_EARLYEER3.0931e-020.3653image
ENSG00000071655.16,MBD3PAADGSVA_HALLMARK_ESTROGEN_RESPONSE_EARLYEAG3.2311e-020.3626image
ENSG00000071655.16,MBD3PCPGGSVA_HALLMARK_ADIPOGENESISEAG8.9945e-030.4412image
chr19:1586549-1590644:-PCPGGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEER1.3990e-020.4238image
chr19:1586549-1590644:-PRADGSVA_HALLMARK_MYOGENESISEER1.6397e-020.1418image
ENSG00000071655.16,MBD3PRADGSVA_HALLMARK_MYOGENESISEAG2.1370e-020.1353image
ENSG00000071655.16,MBD3READGSVA_HALLMARK_APICAL_JUNCTIONEAG3.6261e-04-0.4637image
chr19:1586549-1590644:-READGSVA_HALLMARK_APICAL_JUNCTIONEER3.6261e-04-0.4637image
chr19:1586549-1590644:-SARCGSVA_HALLMARK_HEME_METABOLISMEER4.2350e-030.2823image
ENSG00000071655.16,MBD3SARCGSVA_HALLMARK_HEME_METABOLISMEAG5.5673e-030.2700image
ENSG00000071655.16,MBD3SKCMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG3.1003e-030.1838image
chr19:1586549-1590644:-SKCMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER2.9746e-030.1846image
chr19:1586549-1590644:-STADGSVA_HALLMARK_COAGULATIONEER5.8187e-030.1513image
ENSG00000071655.16,MBD3STADGSVA_HALLMARK_COAGULATIONEAG5.9453e-030.1507image
ENSG00000071655.16,MBD3TGCTGSVA_HALLMARK_UNFOLDED_PROTEIN_RESPONSEEAG8.3712e-03-0.3173image
chr19:1586549-1590644:-TGCTGSVA_HALLMARK_UNFOLDED_PROTEIN_RESPONSEEER9.9605e-03-0.3151image
ENSG00000071655.16,MBD3THCAGSVA_HALLMARK_MTORC1_SIGNALINGEAG5.4465e-030.2462image
chr19:1586549-1590644:-THCAGSVA_HALLMARK_MTORC1_SIGNALINGEER5.7166e-030.2458image


Top

7. Enriched editing regions and drugs for MBD3


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
ENSG00000071655.16,MBD3ACCBI.2536EAG1.5023e-020.5352image
ENSG00000071655.16,MBD3BLCABIRB.0796EAG1.1159e-030.2671image
chr19:1586549-1590644:-BLCABIRB.0796EER1.4090e-030.2628image
ENSG00000071655.16,MBD3BRCAMG.132EAG7.7231e-03-0.1031image
chr19:1586549-1590644:-BRCAMG.132EER2.5710e-03-0.1177image
chr19:1586549-1590644:-CESCDasatinibEER5.6812e-07-0.4206image
ENSG00000071655.16,MBD3CESCDasatinibEAG8.7624e-07-0.4113image
ENSG00000071655.16,MBD3COADCCT007093EAG4.5517e-04-0.2865image
chr19:1586549-1590644:-COADCCT007093EER6.4263e-05-0.3246image
chr19:1586549-1590644:-ESCAGDC.0449EER2.6254e-03-0.2393image
ENSG00000071655.16,MBD3ESCAGDC.0449EAG2.5810e-03-0.2397image
chr19:1586549-1590644:-GBMGNF.2EER1.7155e-08-0.5040image
ENSG00000071655.16,MBD3GBMGNF.2EAG1.0497e-08-0.5104image
chr19:1586549-1590644:-HNSCAZD.0530EER1.2442e-02-0.1769image
ENSG00000071655.16,MBD3HNSCAZD.0530EAG1.3888e-02-0.1742image
ENSG00000071655.16,MBD3KICHCMKEAG2.4419e-02-0.4100image
chr19:1586549-1590644:-KIRCMG.132EER1.8355e-02-0.1851image
ENSG00000071655.16,MBD3KIRCEtoposideEAG2.1360e-020.1807image
ENSG00000071655.16,MBD3KIRPA.770041EAG7.6583e-03-0.2486image
chr19:1586549-1590644:-KIRPA.770041EER1.0160e-02-0.2409image
chr19:1586549-1590644:-LAMLErlotinibEER2.6081e-03-0.2441image
ENSG00000071655.16,MBD3LAMLBicalutamideEAG1.1201e-03-0.2635image
chr19:1586549-1590644:-LGGABT.888EER4.6332e-050.1979image
ENSG00000071655.16,MBD3LGGABT.888EAG5.0543e-050.1967image
ENSG00000071655.16,MBD3LIHCDMOGEAG5.7636e-04-0.4495image
chr19:1586549-1590644:-LIHCBAY.61.3606EER8.9892e-050.5074image
ENSG00000071655.16,MBD3LUSCAZD7762EAG2.8193e-02-0.1305image
chr19:1586549-1590644:-LUSCAZD7762EER2.8258e-02-0.1304image
ENSG00000071655.16,MBD3MESOBX.795EAG4.7314e-02-0.3196image
ENSG00000071655.16,MBD3OVCisplatinEAG2.1896e-030.2108image
chr19:1586549-1590644:-OVAxitinibEER1.1394e-020.1773image
chr19:1573809-1574239:-OVAZD8055EER1.0698e-02-0.5111image
chr19:1586549-1590644:-PAADAZD.2281EER1.8698e-020.3955image
ENSG00000071655.16,MBD3PAADAZD.2281EAG1.8563e-020.3959image
chr19:1586549-1590644:-PRADCytarabineEER4.0746e-040.2077image
ENSG00000071655.16,MBD3PRADCytarabineEAG4.4644e-040.2052image
chr19:1586549-1590644:-READMetforminEER5.4545e-04-0.4512image
ENSG00000071655.16,MBD3READMetforminEAG5.4545e-04-0.4512image
chr19:1586549-1590644:-SARCJW.7.52.1EER1.6702e-03-0.3089image
ENSG00000071655.16,MBD3SARCJW.7.52.1EAG1.5758e-03-0.3061image
chr19:1586549-1590644:-SKCMEpothilone.BEER4.7920e-030.1754image
ENSG00000071655.16,MBD3SKCMBI.D1870EAG4.8244e-030.1753image
ENSG00000071655.16,MBD3STADCisplatinEAG1.1759e-02-0.1381image
chr19:1586549-1590644:-STADCisplatinEER1.2208e-02-0.1376image
ENSG00000071655.16,MBD3TGCTCisplatinEAG1.5039e-020.2938image
chr19:1586549-1590644:-TGCTEHT.1864EER1.9807e-03-0.3740image
ENSG00000071655.16,MBD3THYMBMS.536924EAG3.5106e-04-0.4727image
ENSG00000071655.16,MBD3UCECBMS.708163EAG3.0879e-02-0.2914image
chr19:1586549-1590644:-UVMDMOGEER4.2243e-02-0.3796image
ENSG00000071655.16,MBD3UVMDMOGEAG4.2243e-02-0.3796image


Top

check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType