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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: SMAD9 (ImmuneEditome ID:4093)

1. Gene summary of enriched editing regions for SMAD9

check button Gene summary
Gene informationGene symbol

SMAD9

Gene ID

4093

GeneSynonymsMADH6|MADH9|PPH2|SMAD8|SMAD8/9|SMAD8A|SMAD8B
GeneCytomap

13q13.3

GeneTypeprotein-coding
GeneDescriptionmothers against decapentaplegic homolog 9|MAD homolog 9|Mothers against decapentaplegic, drosophila, homolog of, 9|SMAD, mothers against DPP homolog 9
GeneModificationdate20230404
UniprotIDO15198;A0A7I2R5A4;A0A024RDR3
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr13:36845982-36846461:-ENST00000350148.8ENSG00000120693.12SMAD9UTR3AluSc,FRAMchr13:36845982-36846461:-.alignment
chr13:36845982-36846461:-ENST00000379826.4ENSG00000120693.12SMAD9UTR3AluSc,FRAMchr13:36845982-36846461:-.alignment
chr13:36845982-36846461:-ENST00000399275.5ENSG00000120693.12SMAD9UTR3AluSc,FRAMchr13:36845982-36846461:-.alignment


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2. Tumor-specific enriched editing regions for SMAD9


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chr13:36845982-36846461:-BRCAEER4.5440e-02image
chr13:36845982-36846461:-KIRCEER1.0713e-05image
ENSG00000120693.12,SMAD9KIRCEAG1.0661e-05image
chr13:36845982-36846461:-KIRPEER6.8072e-06image
ENSG00000120693.12,SMAD9KIRPEAG6.8072e-06image
chr13:36845982-36846461:-THCAEER2.6357e-06image
ENSG00000120693.12,SMAD9THCAEAG2.6313e-06image


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
ENSG00000120693.12,SMAD9THCAPathEAG2.1337e-025.1318e-030.1299image
chr13:36845982-36846461:-THCAPathEER2.1318e-025.1239e-030.1299image


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
chr13:36845982-36846461:-MESOEER1.6567e-021.8973e-024.8796e-04image
ENSG00000120693.12,SMAD9MESOEAG1.6567e-021.8973e-024.8796e-04image
chr13:36845982-36846461:-OVEER3.7154e-022.2564e-027.0897e-03image
ENSG00000120693.12,SMAD9OVEAG3.7154e-022.2564e-027.0897e-03image
chr13:36845982-36846461:-STADEER5.5256e-031.9584e-047.2911e+02image
ENSG00000120693.12,SMAD9STADEAG6.4813e-042.3959e-047.1200e+02image

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3. Enriched editing regions and immune related genes for SMAD9


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr13:36845982-36846461:-THCAEERENSG00000186866,POFUT2-0.41655.9362e-186.0810e-20-0.4070imageNELAVL1;RBFOX2NAB_cells_naiveGSVA_HALLMARK_ESTROGEN_RESPONSE_LATE
chr13:36845982-36846461:-THCAEERENSG00000186866,POFUT2-0.41655.9362e-186.0810e-20-0.4070imageNELAVL1;RBFOX2NAB_cells_naiveGSVA_HALLMARK_ESTROGEN_RESPONSE_LATE
chr13:36845982-36846461:-THCAEERENSG00000186866,POFUT2-0.41655.9362e-186.0810e-20-0.4070imageNELAVL1;RBFOX2NAB_cells_naiveGSVA_HALLMARK_ESTROGEN_RESPONSE_LATE

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4. Enriched editing regions and immune related splicing for SMAD9


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000120693.12,SMAD9
GBMEAGIRENSG00000130175.5chr1911449265:11449882:11450428:11450716-0.43821.1934e-043.2587e-09-0.4556imageNADAR;AIFM1;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CNBP;CSTF2T;DGCR8;DHX9;DICER1;EIF4A3;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;FXR2;GTF2F1;HNRNPA1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS2;KHDRBS3;LARP4B;LARP7;LIN28;LIN28A;LIN28B;MOV10;MSI1;MSI2;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM5;RNF219;SBDS;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;YTHDC1;YTHDF1;YWHAG;ZNF184PRKCSHMacrophages_M0GSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr13:36845982-36846461:-
GBMEERIRENSG00000130175.5chr1911449265:11449882:11450428:11450716-0.43821.1125e-043.2587e-09-0.4556imageNELAVL1;RBFOX2PRKCSHMacrophages_M0GSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE

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5. Enriched editing regions and immune infiltration for SMAD9


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chr13:36845982-36846461:-BLCAEERMacrophages_M11.5201e-030.4211image
ENSG00000120693.12,SMAD9BLCAEAGMacrophages_M11.5201e-030.4211image
chr13:36845982-36846461:-COADEERT_cells_regulatory_(Tregs)2.3281e-020.2326image
ENSG00000120693.12,SMAD9COADEAGPlasma_cells2.8239e-02-0.2228image
chr13:36845982-36846461:-GBMEERMacrophages_M05.2256e-03-0.2212image
ENSG00000120693.12,SMAD9GBMEAGMacrophages_M05.2256e-03-0.2212image
chr13:36845982-36846461:-KIRCEERT_cells_gamma_delta2.1576e-030.1673image
ENSG00000120693.12,SMAD9KIRCEAGT_cells_gamma_delta2.1576e-030.1673image
chr13:36845982-36846461:-KIRPEERMacrophages_M11.0972e-040.2708image
ENSG00000120693.12,SMAD9KIRPEAGMacrophages_M11.0972e-040.2708image
chr13:36845982-36846461:-LGGEERMonocytes1.2140e-050.1920image
ENSG00000120693.12,SMAD9LGGEAGMonocytes1.2140e-050.1920image
chr13:36845982-36846461:-LUADEERNK_cells_activated8.8744e-030.2322image
ENSG00000120693.12,SMAD9LUADEAGNK_cells_activated9.8770e-030.2291image
chr13:36845982-36846461:-LUSCEERDendritic_cells_activated5.0043e-040.4053image
ENSG00000120693.12,SMAD9LUSCEAGDendritic_cells_activated6.3918e-040.3982image
chr13:36845982-36846461:-OVEERB_cells_naive4.2204e-02-0.2453image
ENSG00000120693.12,SMAD9OVEAGB_cells_naive4.2204e-02-0.2453image
ENSG00000120693.12,SMAD9PAADEAGMacrophages_M23.7006e-03-0.3753image
chr13:36845982-36846461:-PCPGEERT_cells_CD4_memory_resting1.0423e-02-0.2350image
ENSG00000120693.12,SMAD9PCPGEAGT_cells_CD4_memory_resting1.0423e-02-0.2350image
chr13:36845982-36846461:-PRADEERT_cells_regulatory_(Tregs)5.2314e-030.1297image
ENSG00000120693.12,SMAD9PRADEAGT_cells_regulatory_(Tregs)8.5391e-030.1220image
chr13:36845982-36846461:-SARCEERMacrophages_M12.8352e-020.2422image
ENSG00000120693.12,SMAD9SARCEAGMacrophages_M12.8352e-020.2422image
chr13:36845982-36846461:-SKCMEERT_cells_CD82.2229e-020.3196image
ENSG00000120693.12,SMAD9SKCMEAGT_cells_CD82.2229e-020.3196image
chr13:36845982-36846461:-STADEERMacrophages_M16.2945e-030.2267image
ENSG00000120693.12,SMAD9STADEAGMacrophages_M16.7374e-030.2241image
chr13:36845982-36846461:-TGCTEERT_cells_CD4_memory_activated3.2745e-030.3310image
ENSG00000120693.12,SMAD9TGCTEAGT_cells_CD4_memory_activated3.2745e-030.3310image
chr13:36845982-36846461:-THCAEERB_cells_naive4.4326e-040.1624image
ENSG00000120693.12,SMAD9THCAEAGB_cells_naive4.4323e-040.1624image
chr13:36845982-36846461:-THYMEERT_cells_follicular_helper1.6395e-020.3921image
ENSG00000120693.12,SMAD9THYMEAGT_cells_follicular_helper1.6395e-020.3921image
chr13:36845982-36846461:-UCECEERDendritic_cells_activated3.5088e-040.4769image
ENSG00000120693.12,SMAD9UCECEAGDendritic_cells_activated3.5088e-040.4769image


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6. Enriched editing regions and immune gene sets for SMAD9


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
ENSG00000120693.12,SMAD9BLCAGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG1.8319e-050.5475image
chr13:36845982-36846461:-BLCAGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER1.8319e-050.5475image
ENSG00000120693.12,SMAD9BRCAGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEAG2.2867e-040.2664image
chr13:36845982-36846461:-BRCAGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEER4.9415e-040.2523image
ENSG00000120693.12,SMAD9CESCGSVA_HALLMARK_SPERMATOGENESISEAG2.8652e-02-0.4774image
chr13:36845982-36846461:-COADGSVA_HALLMARK_COMPLEMENTEER1.8938e-060.4665image
ENSG00000120693.12,SMAD9COADGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG4.2177e-050.4032image
ENSG00000120693.12,SMAD9GBMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG5.2872e-040.2726image
chr13:36845982-36846461:-GBMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER5.2872e-040.2726image
ENSG00000120693.12,SMAD9HNSCGSVA_HALLMARK_UV_RESPONSE_UPEAG1.5956e-040.6847image
chr13:36845982-36846461:-KIRCGSVA_HALLMARK_PANCREAS_BETA_CELLSEER1.9685e-060.2568image
ENSG00000120693.12,SMAD9KIRCGSVA_HALLMARK_PANCREAS_BETA_CELLSEAG1.9685e-060.2568image
chr13:36845982-36846461:-KIRPGSVA_HALLMARK_XENOBIOTIC_METABOLISMEER6.2414e-050.2799image
ENSG00000120693.12,SMAD9KIRPGSVA_HALLMARK_XENOBIOTIC_METABOLISMEAG6.2414e-050.2799image
ENSG00000120693.12,SMAD9LGGGSVA_HALLMARK_BILE_ACID_METABOLISMEAG4.3877e-100.2712image
chr13:36845982-36846461:-LGGGSVA_HALLMARK_BILE_ACID_METABOLISMEER4.3877e-100.2712image
chr13:36845982-36846461:-LUADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER4.4282e-040.3084image
ENSG00000120693.12,SMAD9LUADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG5.3663e-040.3041image
chr13:36845982-36846461:-LUSCGSVA_HALLMARK_HYPOXIAEER3.6698e-030.3428image
ENSG00000120693.12,SMAD9LUSCGSVA_HALLMARK_HYPOXIAEAG3.3434e-030.3460image
chr13:36845982-36846461:-MESOGSVA_HALLMARK_HEDGEHOG_SIGNALINGEER2.5341e-03-0.5988image
ENSG00000120693.12,SMAD9MESOGSVA_HALLMARK_HEDGEHOG_SIGNALINGEAG2.5341e-03-0.5988image
chr13:36845982-36846461:-OVGSVA_HALLMARK_HEDGEHOG_SIGNALINGEER1.1664e-02-0.3020image
ENSG00000120693.12,SMAD9OVGSVA_HALLMARK_HEDGEHOG_SIGNALINGEAG1.1664e-02-0.3020image
ENSG00000120693.12,SMAD9PAADGSVA_HALLMARK_PROTEIN_SECRETIONEAG1.8095e-02-0.3094image
chr13:36845982-36846461:-PCPGGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.8717e-040.3374image
ENSG00000120693.12,SMAD9PCPGGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG1.8717e-040.3374image
ENSG00000120693.12,SMAD9PRADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG2.4333e-070.2369image
chr13:36845982-36846461:-PRADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER2.8194e-070.2362image
ENSG00000120693.12,SMAD9READGSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALINGEAG3.4142e-03-0.4631image
ENSG00000120693.12,SMAD9SARCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG3.0012e-040.3893image
chr13:36845982-36846461:-SARCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER3.0012e-040.3893image
chr13:36845982-36846461:-SKCMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER2.6923e-040.4892image
ENSG00000120693.12,SMAD9SKCMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG2.6923e-040.4892image
ENSG00000120693.12,SMAD9STADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG8.9607e-060.3595image
chr13:36845982-36846461:-STADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER7.3451e-060.3639image
ENSG00000120693.12,SMAD9TGCTGSVA_HALLMARK_DNA_REPAIREAG1.8371e-030.3495image
chr13:36845982-36846461:-TGCTGSVA_HALLMARK_DNA_REPAIREER1.8371e-030.3495image
chr13:36845982-36846461:-THCAGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER1.3388e-140.3473image
ENSG00000120693.12,SMAD9THCAGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG1.3413e-140.3473image
chr13:36845982-36846461:-THYMGSVA_HALLMARK_TGF_BETA_SIGNALINGEER4.5447e-03-0.4562image
ENSG00000120693.12,SMAD9THYMGSVA_HALLMARK_TGF_BETA_SIGNALINGEAG4.5447e-03-0.4562image
chr13:36845982-36846461:-UCECGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.3741e-030.4322image
ENSG00000120693.12,SMAD9UCECGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG1.3741e-030.4322image


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7. Enriched editing regions and drugs for SMAD9


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
chr13:36845982-36846461:-BLCACGP.60474EER2.4305e-03-0.4043image
ENSG00000120693.12,SMAD9BLCACGP.60474EAG2.4305e-03-0.4043image
ENSG00000120693.12,SMAD9BRCAA.443654EAG3.8934e-02-0.1511image
chr13:36845982-36846461:-BRCABMS.754807EER3.3484e-020.1556image
ENSG00000120693.12,SMAD9CESCCI.1040EAG1.8088e-03-0.6393image
chr13:36845982-36846461:-COADBIRB.0796EER3.2241e-040.3612image
ENSG00000120693.12,SMAD9COADAICAREAG6.5225e-05-0.3940image
chr13:36845982-36846461:-ESCAGefitinibEER1.8116e-02-0.2798image
ENSG00000120693.12,SMAD9ESCAGefitinibEAG1.3909e-02-0.2907image
chr13:36845982-36846461:-GBMIPA.3EER1.1236e-030.2568image
ENSG00000120693.12,SMAD9GBMIPA.3EAG1.1236e-030.2568image
ENSG00000120693.12,SMAD9HNSCJNK.9LEAG1.8615e-020.4669image
ENSG00000120693.12,SMAD9KIRCAP.24534EAG3.1259e-060.2519image
chr13:36845982-36846461:-KIRCAP.24534EER3.1259e-060.2519image
chr13:36845982-36846461:-KIRPFTI.277EER9.0449e-060.3089image
ENSG00000120693.12,SMAD9KIRPFTI.277EAG9.0449e-060.3089image
ENSG00000120693.12,SMAD9LGGAxitinibEAG3.0635e-150.3391image
chr13:36845982-36846461:-LGGAxitinibEER3.0635e-150.3391image
ENSG00000120693.12,SMAD9LUSCCGP.60474EAG5.9670e-03-0.3255image
chr13:36845982-36846461:-LUSCCGP.60474EER5.0952e-03-0.3312image
chr13:36845982-36846461:-MESOErlotinibEER5.0166e-04-0.6675image
ENSG00000120693.12,SMAD9MESOErlotinibEAG5.0166e-04-0.6675image
chr13:36845982-36846461:-OVBMS.708163EER1.6060e-02-0.2889image
ENSG00000120693.12,SMAD9OVBMS.708163EAG1.6060e-02-0.2889image
ENSG00000120693.12,SMAD9PAADCI.1040EAG5.6210e-03-0.3592image
chr13:36845982-36846461:-PCPGBosutinibEER1.1019e-020.2333image
ENSG00000120693.12,SMAD9PCPGBosutinibEAG1.1019e-020.2333image
ENSG00000120693.12,SMAD9PRADFH535EAG1.9631e-060.2188image
chr13:36845982-36846461:-PRADFH535EER2.7861e-060.2160image
ENSG00000120693.12,SMAD9READCisplatinEAG1.4736e-020.3927image
chr13:36845982-36846461:-SARCAxitinibEER7.3978e-060.4725image
ENSG00000120693.12,SMAD9SARCAxitinibEAG7.3978e-060.4725image
chr13:36845982-36846461:-SKCMAxitinibEER2.1590e-030.4199image
ENSG00000120693.12,SMAD9SKCMAxitinibEAG2.1590e-030.4199image
ENSG00000120693.12,SMAD9STADGW.441756EAG5.4445e-04-0.2837image
chr13:36845982-36846461:-STADImatinibEER6.7839e-040.2799image
ENSG00000120693.12,SMAD9TGCTAZD6482EAG2.0676e-030.3458image
chr13:36845982-36846461:-TGCTAZD6482EER2.0676e-030.3458image
ENSG00000120693.12,SMAD9THCACI.1040EAG7.4285e-16-0.3625image
chr13:36845982-36846461:-THCACI.1040EER7.3819e-16-0.3625image
chr13:36845982-36846461:-THYMAKT.inhibitor.VIIIEER1.8832e-030.4941image
ENSG00000120693.12,SMAD9THYMAKT.inhibitor.VIIIEAG1.8832e-030.4941image
chr13:36845982-36846461:-UCECA.443654EER5.7941e-03-0.3775image
ENSG00000120693.12,SMAD9UCECA.443654EAG5.7941e-03-0.3775image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType