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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: ZNF789 (ImmuneEditome ID:285989)

1. Gene summary of enriched editing regions for ZNF789

check button Gene summary
Gene informationGene symbol

ZNF789

Gene ID

285989

GeneSynonyms-
GeneCytomap

7q22.1

GeneTypeprotein-coding
GeneDescriptionzinc finger protein 789
GeneModificationdate20230518
UniprotIDQ5FWF6;C9JUE3;C9J487;F8WEN0;C9J3R7
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr7:99473597-99475947:+ENST00000465438.1ENSG00000198556.12ZNF789ncRNA_intronicMER95,AluJo,MER89,AluSg,AluSq2,MER30,AluSc8,AluYchr7:99473597-99475947:+.alignment
chr7:99473597-99475947:+ENST00000481472.4ENSG00000198556.12ZNF789ncRNA_intronicMER95,AluJo,MER89,AluSg,AluSq2,MER30,AluSc8,AluYchr7:99473597-99475947:+.alignment
chr7:99473597-99475947:+ENST00000488485.4ENSG00000198556.12ZNF789ncRNA_intronicMER95,AluJo,MER89,AluSg,AluSq2,MER30,AluSc8,AluYchr7:99473597-99475947:+.alignment
chr7:99477094-99477918:+ENST00000465438.1ENSG00000198556.12ZNF789ncRNA_intronicAluSq2,AluSc,AluJbchr7:99477094-99477918:+.alignment
chr7:99477094-99477918:+ENST00000468705.1ENSG00000198556.12ZNF789ncRNA_intronicAluSq2,AluSc,AluJbchr7:99477094-99477918:+.alignment
chr7:99477094-99477918:+ENST00000481472.4ENSG00000198556.12ZNF789ncRNA_intronicAluSq2,AluSc,AluJbchr7:99477094-99477918:+.alignment
chr7:99477094-99477918:+ENST00000488485.4ENSG00000198556.12ZNF789ncRNA_intronicAluSq2,AluSc,AluJbchr7:99477094-99477918:+.alignment
chr7:99481431-99483621:+ENST00000379724.3ENSG00000198556.12ZNF789exonicL1ME4a,Tigger4,Tigger4b,AluSp,(AAAT)n,AluSq2,(AC)n,AluSxchr7:99481431-99483621:+.alignment


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2. Tumor-specific enriched editing regions for ZNF789


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
ENSG00000198556.12,ZNF789KIRCEAG1.1490e-02image
ENSG00000198556.12,ZNF789THCAEAG1.4422e-02image


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
ENSG00000198556.12,ZNF789KIRCPathEAG7.4707e-036.3663e-030.1900image
chr7:99477094-99477918:+OVCliEER3.6498e-021.4316e-020.4932image


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot

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3. Enriched editing regions and immune related genes for ZNF789


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark

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4. Enriched editing regions and immune related splicing for ZNF789


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000198556.12,ZNF789
GBMEAGIRENSG00000100650.11chr1469769745:69770042:69770466:697705400.40812.8868e-036.5662e-080.4477imageNADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FKBP4;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP7;LIN28;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RNF219;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAT_cells_CD8GSVA_HALLMARK_ADIPOGENESIS
ENSG00000198556.12,ZNF789
GBMEAGIRENSG00000115204.10chr227311898:27312246:27312405:273124530.29993.1340e-021.2371e-050.4001imageNADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FKBP4;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP7;LIN28;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RNF219;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZNF184NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_ADIPOGENESIS

More results



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5. Enriched editing regions and immune infiltration for ZNF789


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
ENSG00000198556.12,ZNF789BLCAEAGPlasma_cells4.7681e-020.1985image
chr7:99481431-99483621:+BRCAEERMacrophages_M02.7988e-02-0.1382image
ENSG00000198556.12,ZNF789BRCAEAGT_cells_gamma_delta2.6106e-020.1038image
ENSG00000198556.12,ZNF789CESCEAGT_cells_gamma_delta1.3200e-020.3237image
chr7:99481431-99483621:+COADEERMast_cells_activated2.7177e-030.3213image
ENSG00000198556.12,ZNF789COADEAGMast_cells_activated2.2903e-040.3264image
chr7:99481431-99483621:+ESCAEERB_cells_naive1.3054e-02-0.2462image
ENSG00000198556.12,ZNF789ESCAEAGT_cells_CD83.5627e-020.1904image
ENSG00000198556.12,ZNF789GBMEAGMacrophages_M21.1996e-02-0.2173image
ENSG00000198556.12,ZNF789KICHEAGT_cells_regulatory_(Tregs)3.8763e-020.4652image
chr7:99481431-99483621:+KIRCEERNK_cells_resting9.3633e-030.2725image
ENSG00000198556.12,ZNF789KIRCEAGDendritic_cells_activated3.6506e-030.2459image
chr7:99481431-99483621:+KIRPEEREosinophils3.5864e-020.1942image
ENSG00000198556.12,ZNF789KIRPEAGT_cells_CD4_memory_activated3.6475e-030.2329image
ENSG00000198556.12,ZNF789LAMLEAGNeutrophils2.7898e-020.2793image
ENSG00000198556.12,ZNF789LGGEAGMacrophages_M13.6219e-02-0.1208image
ENSG00000198556.12,ZNF789LIHCEAGNK_cells_resting3.5546e-020.4309image
chr7:99481431-99483621:+LUADEERMast_cells_activated2.8593e-02-0.2127image
chr7:99473597-99475947:+LUSCEERNeutrophils4.4916e-020.3890image
chr7:99477094-99477918:+LUSCEERT_cells_follicular_helper3.4520e-030.5521image
ENSG00000198556.12,ZNF789LUSCEAGT_cells_gamma_delta3.1065e-03-0.2262image
chr7:99477094-99477918:+OVEERNeutrophils2.5946e-02-0.4965image
chr7:99481431-99483621:+OVEERPlasma_cells6.8200e-050.3006image
chr7:99481431-99483621:+PAADEERMacrophages_M11.5348e-02-0.3856image
chr7:99481431-99483621:+PCPGEERMacrophages_M12.0726e-020.3477image
ENSG00000198556.12,ZNF789PRADEAGDendritic_cells_resting6.3281e-03-0.1455image
ENSG00000198556.12,ZNF789READEAGNK_cells_resting6.9484e-050.5575image
chr7:99481431-99483621:+SKCMEERT_cells_CD82.1520e-020.1621image
ENSG00000198556.12,ZNF789SKCMEAGMacrophages_M09.8840e-03-0.1582image
chr7:99477094-99477918:+STADEERMast_cells_activated4.2181e-02-0.2509image
chr7:99481431-99483621:+STADEERMacrophages_M27.2147e-040.2438image
ENSG00000198556.12,ZNF789STADEAGMacrophages_M22.0320e-020.1467image
ENSG00000198556.12,ZNF789TGCTEAGNeutrophils4.0552e-020.2878image
chr7:99481431-99483621:+THCAEERMacrophages_M25.2387e-030.2034image
chr7:99481431-99483621:+THYMEERMacrophages_M18.6839e-030.3747image
ENSG00000198556.12,ZNF789THYMEAGT_cells_CD81.6875e-020.3269image
chr7:99481431-99483621:+UCECEERB_cells_memory4.2881e-020.3660image
chr7:99481431-99483621:+UVMEERDendritic_cells_activated4.9769e-020.3964image
ENSG00000198556.12,ZNF789UVMEAGDendritic_cells_activated2.1878e-020.4170image


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6. Enriched editing regions and immune gene sets for ZNF789


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
chr7:99481431-99483621:+BLCAGSVA_HALLMARK_PROTEIN_SECRETIONEER2.5812e-030.3305image
ENSG00000198556.12,ZNF789BLCAGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG1.7096e-020.2380image
ENSG00000198556.12,ZNF789BRCAGSVA_HALLMARK_UV_RESPONSE_DNEAG2.7253e-030.1396image
chr7:99481431-99483621:+BRCAGSVA_HALLMARK_PROTEIN_SECRETIONEER2.3263e-050.2626image
ENSG00000198556.12,ZNF789CESCGSVA_HALLMARK_PEROXISOMEEAG2.5630e-02-0.2930image
ENSG00000198556.12,ZNF789COADGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEAG1.7789e-04-0.3318image
chr7:99481431-99483621:+COADGSVA_HALLMARK_INFLAMMATORY_RESPONSEEER1.2101e-020.2711image
chr7:99477094-99477918:+ESCAGSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITIONEER6.8918e-030.3571image
chr7:99473597-99475947:+ESCAGSVA_HALLMARK_HEDGEHOG_SIGNALINGEER1.2533e-020.3013image
chr7:99481431-99483621:+ESCAGSVA_HALLMARK_P53_PATHWAYEER1.4041e-030.3136image
chr7:99481431-99483621:+GBMGSVA_HALLMARK_IL2_STAT5_SIGNALINGEER9.2423e-050.3791image
ENSG00000198556.12,ZNF789GBMGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEAG1.8675e-03-0.2673image
ENSG00000198556.12,ZNF789KIRCGSVA_HALLMARK_HEME_METABOLISMEAG1.9846e-02-0.1981image
chr7:99481431-99483621:+KIRCGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEER4.0687e-020.2162image
ENSG00000198556.12,ZNF789KIRPGSVA_HALLMARK_ANDROGEN_RESPONSEEAG1.5515e-02-0.1947image
chr7:99481431-99483621:+KIRPGSVA_HALLMARK_PANCREAS_BETA_CELLSEER5.9584e-030.2528image
ENSG00000198556.12,ZNF789LGGGSVA_HALLMARK_APICAL_JUNCTIONEAG9.0327e-04-0.1904image
chr7:99481431-99483621:+LGGGSVA_HALLMARK_HEME_METABOLISMEER4.1767e-050.2628image
ENSG00000198556.12,ZNF789LIHCGSVA_HALLMARK_G2M_CHECKPOINTEAG8.6600e-04-0.6346image
chr7:99481431-99483621:+LUADGSVA_HALLMARK_ANDROGEN_RESPONSEEER2.6319e-030.2893image
ENSG00000198556.12,ZNF789LUSCGSVA_HALLMARK_BILE_ACID_METABOLISMEAG1.3707e-04-0.2892image
chr7:99481431-99483621:+LUSCGSVA_HALLMARK_IL2_STAT5_SIGNALINGEER2.0063e-020.2225image
chr7:99477094-99477918:+OVGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEER2.8544e-020.4893image
chr7:99481431-99483621:+OVGSVA_HALLMARK_PANCREAS_BETA_CELLSEER2.2850e-050.3187image
ENSG00000198556.12,ZNF789OVGSVA_HALLMARK_PANCREAS_BETA_CELLSEAG3.1119e-030.2129image
chr7:99481431-99483621:+PAADGSVA_HALLMARK_PANCREAS_BETA_CELLSEER9.7163e-03-0.4091image
ENSG00000198556.12,ZNF789PAADGSVA_HALLMARK_ANGIOGENESISEAG7.4078e-03-0.3605image
ENSG00000198556.12,ZNF789PCPGGSVA_HALLMARK_PEROXISOMEEAG1.3975e-020.3035image
chr7:99481431-99483621:+PCPGGSVA_HALLMARK_UV_RESPONSE_DNEER1.0025e-040.5527image
ENSG00000198556.12,ZNF789PRADGSVA_HALLMARK_MITOTIC_SPINDLEEAG6.3169e-04-0.1816image
chr7:99481431-99483621:+PRADGSVA_HALLMARK_NOTCH_SIGNALINGEER1.3872e-050.2674image
ENSG00000198556.12,ZNF789READGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG4.6043e-02-0.2990image
chr7:99481431-99483621:+SARCGSVA_HALLMARK_UV_RESPONSE_UPEER8.6580e-030.4784image
chr7:99481431-99483621:+SKCMGSVA_HALLMARK_APOPTOSISEER1.4093e-050.3010image
chr7:99477094-99477918:+STADGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEER1.8005e-020.2904image
ENSG00000198556.12,ZNF789STADGSVA_HALLMARK_ESTROGEN_RESPONSE_EARLYEAG5.0929e-04-0.2183image
chr7:99481431-99483621:+STADGSVA_HALLMARK_MYC_TARGETS_V1EER3.7415e-030.2099image
ENSG00000198556.12,ZNF789TGCTGSVA_HALLMARK_MITOTIC_SPINDLEEAG2.7016e-02-0.3097image
chr7:99481431-99483621:+THCAGSVA_HALLMARK_HYPOXIAEER9.5608e-050.2814image
ENSG00000198556.12,ZNF789THCAGSVA_HALLMARK_DNA_REPAIREAG1.7779e-020.1444image
ENSG00000198556.12,ZNF789THYMGSVA_HALLMARK_APOPTOSISEAG1.3001e-030.4303image
chr7:99481431-99483621:+THYMGSVA_HALLMARK_HYPOXIAEER3.7782e-040.4924image
ENSG00000198556.12,ZNF789UCECGSVA_HALLMARK_MITOTIC_SPINDLEEAG1.4541e-02-0.3745image
chr7:99481431-99483621:+UVMGSVA_HALLMARK_UV_RESPONSE_UPEER4.0318e-030.5544image
ENSG00000198556.12,ZNF789UVMGSVA_HALLMARK_E2F_TARGETSEAG9.8279e-030.4638image


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7. Enriched editing regions and drugs for ZNF789


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
ENSG00000198556.12,ZNF789BLCABMS.708163EAG6.4722e-03-0.2706image
ENSG00000198556.12,ZNF789BRCAImatinibEAG1.8494e-03-0.1450image
chr7:99481431-99483621:+BRCALapatinibEER2.6233e-04-0.2285image
ENSG00000198556.12,ZNF789CESCGSK269962AEAG1.0563e-03-0.4192image
chr7:99481431-99483621:+COADGSK.650394EER1.7237e-040.3965image
ENSG00000198556.12,ZNF789COADBMS.509744EAG2.8099e-060.4080image
chr7:99477094-99477918:+ESCABMS.509744EER1.0825e-02-0.3381image
chr7:99473597-99475947:+ESCAImatinibEER2.0715e-03-0.3671image
ENSG00000198556.12,ZNF789ESCAErlotinibEAG1.1499e-03-0.2909image
chr7:99481431-99483621:+ESCAErlotinibEER3.4829e-05-0.3996image
chr7:99481431-99483621:+GBMBicalutamideEER1.8542e-03-0.3061image
ENSG00000198556.12,ZNF789GBMBIRB.0796EAG1.0664e-02-0.2208image
ENSG00000198556.12,ZNF789KICHEmbelinEAG3.2169e-020.4801image
ENSG00000198556.12,ZNF789KIRCCHIR.99021EAG4.7764e-030.2389image
chr7:99481431-99483621:+KIRCFH535EER1.3218e-02-0.2603image
chr7:99481431-99483621:+KIRPDMOGEER1.4407e-03-0.2913image
ENSG00000198556.12,ZNF789KIRPKU.55933EAG7.3943e-03-0.2151image
chr7:99481431-99483621:+LGGABT.888EER1.0888e-030.2109image
ENSG00000198556.12,ZNF789LGGBexaroteneEAG5.7179e-030.1589image
ENSG00000198556.12,ZNF789LIHCGSK.650394EAG1.3943e-030.6146image
chr7:99481431-99483621:+LUADFH535EER4.2139e-020.1978image
ENSG00000198556.12,ZNF789LUADFH535EAG3.8846e-020.1748image
chr7:99473597-99475947:+LUSCBIBW2992EER8.2726e-03-0.4976image
chr7:99481431-99483621:+LUSCAZD.0530EER1.6153e-02-0.2300image
chr7:99477094-99477918:+LUSCMidostaurinEER1.7966e-020.4603image
ENSG00000198556.12,ZNF789LUSCBortezomibEAG9.0756e-040.2529image
chr7:99477094-99477918:+OVAZD6482EER7.2932e-030.5804image
chr7:99481431-99483621:+OVMG.132EER1.2334e-07-0.3921image
ENSG00000198556.12,ZNF789OVJNK.9LEAG7.9205e-040.2408image
ENSG00000198556.12,ZNF789PAADDocetaxelEAG3.6674e-030.3888image
chr7:99481431-99483621:+PAADDocetaxelEER7.6593e-030.4207image
chr7:99481431-99483621:+PCPGMetforminEER3.0169e-020.3272image
chr7:99481431-99483621:+PRADImatinibEER2.6234e-03-0.1869image
ENSG00000198556.12,ZNF789PRADBMS.536924EAG2.6662e-05-0.2225image
ENSG00000198556.12,ZNF789READCMKEAG6.6963e-040.4882image
chr7:99481431-99483621:+SARCCyclopamineEER3.3892e-02-0.3951image
ENSG00000198556.12,ZNF789SARCA.770041EAG2.4684e-02-0.3309image
chr7:99481431-99483621:+SKCMJNK.9LEER5.0415e-03-0.1971image
chr7:99481431-99483621:+STADGemcitabineEER2.8106e-03-0.2162image
ENSG00000198556.12,ZNF789STADGemcitabineEAG1.3864e-04-0.2387image
chr7:99477094-99477918:+STADAICAREER1.0453e-020.3132image
chr7:99473597-99475947:+STADBMS.536924EER8.8099e-03-0.2372image
ENSG00000198556.12,ZNF789TGCTEtoposideEAG3.1822e-020.3010image
chr7:99481431-99483621:+TGCTCMKEER4.0685e-02-0.3134image
chr7:99481431-99483621:+THCABexaroteneEER8.5650e-04-0.2418image
ENSG00000198556.12,ZNF789THCAA.770041EAG6.7275e-04-0.2061image
chr7:99481431-99483621:+THYMGNF.2EER1.0541e-03-0.4583image
ENSG00000198556.12,ZNF789THYMA.770041EAG1.8575e-03-0.4177image
chr7:99481431-99483621:+UCECJNK.Inhibitor.VIIIEER4.6350e-050.6641image
ENSG00000198556.12,ZNF789UCECJNK.Inhibitor.VIIIEAG4.2048e-040.5197image
chr7:99481431-99483621:+UVMBI.2536EER2.6846e-03-0.5742image
ENSG00000198556.12,ZNF789UVMBI.D1870EAG4.9281e-02-0.3621image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType