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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: ACOT9 (ImmuneEditome ID:23597)

1. Gene summary of enriched editing regions for ACOT9

check button Gene summary
Gene informationGene symbol

ACOT9

Gene ID

23597

GeneSynonymsACATE2|CGI-16|MT-ACT48|MTACT48
GeneCytomap

Xp22.11

GeneTypeprotein-coding
GeneDescriptionacyl-coenzyme A thioesterase 9, mitochondrial|acyl-CoA thioester hydrolase 9|acyl-Coenzyme A thioesterase 2, mitochondrial|mitochondrial Acyl-CoA Thioesterase
GeneModificationdate20230409
UniprotIDQ9Y305;C9J7L8;F8WDI2;H7C5Q2
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chrX:23702315-23703634:-ENST00000379303.8ENSG00000123130.15ACOT9UTR3AluSc8,MIR,(AATT)n,AluSg7chrX:23702315-23703634:-.alignment
chrX:23726749-23726893:-ENST00000336430.10ENSG00000123130.15ACOT9intronicAluSz6,AluSc8chrX:23726749-23726893:-.alignment
chrX:23726749-23726893:-ENST00000379295.4ENSG00000123130.15ACOT9intronicAluSz6,AluSc8chrX:23726749-23726893:-.alignment
chrX:23726749-23726893:-ENST00000379303.8ENSG00000123130.15ACOT9intronicAluSz6,AluSc8chrX:23726749-23726893:-.alignment
chrX:23726749-23726893:-ENST00000473710.4ENSG00000123130.15ACOT9intronicAluSz6,AluSc8chrX:23726749-23726893:-.alignment
chrX:23726749-23726893:-ENST00000492081.1ENSG00000123130.15ACOT9intronicAluSz6,AluSc8chrX:23726749-23726893:-.alignment
chrX:23726749-23726893:-ENST00000494361.4ENSG00000123130.15ACOT9intronicAluSz6,AluSc8chrX:23726749-23726893:-.alignment
chrX:23761509-23762027:-ENST00000379295.4ENSG00000123130.15ACOT9intronicAluSc5,AluSx,(AT)nchrX:23761509-23762027:-.alignment


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2. Tumor-specific enriched editing regions for ACOT9


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chrX:23702315-23703634:-BRCAEER6.8733e-03image
ENSG00000123130.15,ACOT9BRCAEAG5.9517e-03image
chrX:23702315-23703634:-KIRCEER1.7588e-02image
ENSG00000123130.15,ACOT9KIRCEAG1.0109e-02image
chrX:23702315-23703634:-LUSCEER5.9799e-04image
ENSG00000123130.15,ACOT9LUSCEAG6.2662e-04image
chrX:23702315-23703634:-PRADEER4.2555e-03image
ENSG00000123130.15,ACOT9PRADEAG2.5601e-03image


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
ENSG00000123130.15,ACOT9HNSCCliEAG1.0939e-023.7703e-02-0.2272image
chrX:23702315-23703634:-HNSCCliEER9.9379e-033.4865e-02-0.2306image
chrX:23702315-23703634:-LUSCPathEER4.9165e-027.4636e-030.2635image


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
chrX:23702315-23703634:-CESCEER4.2922e-024.4460e-022.1623e-03image
ENSG00000123130.15,ACOT9CESCEAG4.1979e-024.6442e-022.5395e-03image

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3. Enriched editing regions and immune related genes for ACOT9


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chrX:23702315-23703634:-GBMEERENSG00000230409,TCEA1P20.40005.6479e-044.1493e-070.4208imageNNNAMast_cells_restingGSVA_HALLMARK_PROTEIN_SECRETION
chrX:23702315-23703634:-GBMEERENSG00000268412,TRMT112P60.35832.3297e-032.7578e-080.4574imageNNNAT_cells_CD4_memory_activatedGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATION
chrX:23702315-23703634:-GBMEERENSG00000124596,OARD10.34993.9418e-034.6583e-070.4191imageNEIF4A3;ELAVL1;FBL;HNRNPA1;HNRNPC;IGF2BP2;NOP56;NOP58;RBM10;TAF15NAMast_cells_restingGSVA_HALLMARK_ANGIOGENESIS
chrX:23702315-23703634:-GBMEERENSG00000236264,RPL26P300.32241.0137e-021.5120e-070.4349imageNNNANK_cells_restingGSVA_HALLMARK_UV_RESPONSE_DN
chrX:23702315-23703634:-GBMEERENSG00000267390,RP11-635N19.10.31241.4253e-024.9852e-070.4181imageNEIF4A3;FBL;IGF2BP2NANK_cells_restingGSVA_HALLMARK_UV_RESPONSE_DN
chrX:23702315-23703634:-GBMEERENSG00000174276,ZNHIT20.30131.6577e-022.4826e-080.4588imageNEIF4A3;ELAVL1;FBL;IGF2BP2;NOP56NAMast_cells_restingGSVA_HALLMARK_DNA_REPAIR
chrX:23702315-23703634:-GBMEERENSG00000215221,UBA52P60.28202.8031e-026.0273e-080.4473imageNNNAT_cells_CD4_memory_restingGSVA_HALLMARK_MYC_TARGETS_V1

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4. Enriched editing regions and immune related splicing for ACOT9


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000123130.15,ACOT9
GBMEAGIRENSG00000148362.6chr9136992417:136992704:136992924:136992974-0.37945.7026e-038.9783e-07-0.4095imageNACIN1;AUH;BCCIP;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RNF219;SAFB2;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZNF184NAB_cells_naiveGSVA_HALLMARK_BILE_ACID_METABOLISM
chrX:23702315-23703634:-
GBMEERIRENSG00000148362.6chr9136992417:136992704:136992924:136992974-0.37934.9198e-038.9891e-07-0.4095imageNEIF4A3;ELAVL1;FBL;HNRNPA1;HNRNPC;IGF2BP2;NOP56;NOP58;RBM10;TAF15NAB_cells_naiveGSVA_HALLMARK_BILE_ACID_METABOLISM
ENSG00000123130.15,ACOT9
GBMEAGIRENSG00000099783.7chr198465323:8465362:8465479:8465515-0.40084.2004e-035.4570e-07-0.4168imageNACIN1;ADAR;ALYREF;AUH;BCCIP;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RNF219;SAFB2;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAB_cells_memory
chrX:23702315-23703634:-
GBMEERIRENSG00000161526.10chr1775704755:75705693:75706007:75706092-0.39007.3951e-042.1775e-06-0.4340imageNEIF4A3;ELAVL1;FBL;HNRNPA1;HNRNPC;IGF2BP2;NOP56;NOP58;RBM10;TAF15SAP30BPT_cells_CD8GSVA_HALLMARK_ADIPOGENESIS
ENSG00000123130.15,ACOT9
GBMEAGIRENSG00000161526.10chr1775704755:75705693:75706007:75706092-0.39018.2922e-042.1740e-06-0.4340imageNACIN1;ADAR;AUH;BCCIP;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;KHDRBS1;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI1;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;SAFB2;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZNF184SAP30BPT_cells_CD8GSVA_HALLMARK_ADIPOGENESIS
chrX:23702315-23703634:-
GBMEERIRENSG00000099783.7chr198465323:8465362:8465479:8465515-0.40083.5971e-035.4602e-07-0.4168imageNEIF4A3;ELAVL1;FBL;HNRNPA1;HNRNPC;IGF2BP2;NOP56;NOP58;RBM10;TAF15NAB_cells_memory

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5. Enriched editing regions and immune infiltration for ACOT9


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chrX:23702315-23703634:-BRCAEERT_cells_follicular_helper4.4596e-020.1362image
chrX:23702315-23703634:-CESCEERT_cells_follicular_helper3.9100e-030.3360image
ENSG00000123130.15,ACOT9CESCEAGT_cells_follicular_helper3.4150e-030.3383image
ENSG00000123130.15,ACOT9COADEAGDendritic_cells_activated1.3243e-040.5559image
chrX:23702315-23703634:-HNSCEERMacrophages_M07.6482e-03-0.2891image
ENSG00000123130.15,ACOT9HNSCEAGMacrophages_M09.9463e-03-0.2798image
chrX:23702315-23703634:-KIRCEERT_cells_regulatory_(Tregs)2.4218e-020.2209image
ENSG00000123130.15,ACOT9KIRCEAGDendritic_cells_activated2.5561e-130.6377image
chrX:23702315-23703634:-LGGEERT_cells_CD81.8848e-02-0.1620image
ENSG00000123130.15,ACOT9LGGEAGT_cells_CD81.8848e-02-0.1620image
chrX:23702315-23703634:-LUADEERT_cells_follicular_helper2.3113e-020.2127image
ENSG00000123130.15,ACOT9LUADEAGT_cells_follicular_helper2.4739e-020.2067image
chrX:23702315-23703634:-PAADEERDendritic_cells_activated4.0061e-02-0.3108image
ENSG00000123130.15,ACOT9PAADEAGDendritic_cells_activated4.0061e-02-0.3108image
ENSG00000123130.15,ACOT9PCPGEAGT_cells_CD4_memory_resting8.1387e-030.5740image
chrX:23702315-23703634:-PRADEERNK_cells_activated4.9282e-02-0.1807image
ENSG00000123130.15,ACOT9PRADEAGDendritic_cells_activated5.2969e-050.3575image
chrX:23702315-23703634:-SARCEERNK_cells_resting3.0695e-02-0.1795image
ENSG00000123130.15,ACOT9SARCEAGNK_cells_resting3.1450e-02-0.1788image
chrX:23702315-23703634:-SKCMEERT_cells_CD4_memory_activated1.5257e-020.1978image
ENSG00000123130.15,ACOT9SKCMEAGT_cells_CD4_memory_activated2.4192e-020.1840image
chrX:23702315-23703634:-STADEERT_cells_CD4_memory_resting8.0306e-04-0.2290image
ENSG00000123130.15,ACOT9STADEAGT_cells_CD4_memory_resting6.0902e-05-0.2675image
chrX:23702315-23703634:-THCAEERMonocytes3.6546e-020.1318image
ENSG00000123130.15,ACOT9THCAEAGMonocytes3.6952e-020.1312image


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6. Enriched editing regions and immune gene sets for ACOT9


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
chrX:23702315-23703634:-BRCAGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEER3.0319e-030.1999image
ENSG00000123130.15,ACOT9BRCAGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEAG1.8171e-030.2091image
ENSG00000123130.15,ACOT9CESCGSVA_HALLMARK_MYOGENESISEAG1.1632e-02-0.2938image
chrX:23702315-23703634:-CESCGSVA_HALLMARK_MYOGENESISEER1.0674e-02-0.2992image
ENSG00000123130.15,ACOT9COADGSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALINGEAG4.4496e-03-0.4303image
chrX:23702315-23703634:-ESCAGSVA_HALLMARK_KRAS_SIGNALING_DNEER4.7068e-020.1943image
ENSG00000123130.15,ACOT9GBMGSVA_HALLMARK_APICAL_JUNCTIONEAG1.7185e-03-0.2684image
chrX:23702315-23703634:-GBMGSVA_HALLMARK_APICAL_JUNCTIONEER1.7178e-03-0.2684image
ENSG00000123130.15,ACOT9HNSCGSVA_HALLMARK_PANCREAS_BETA_CELLSEAG3.4787e-020.2306image
chrX:23702315-23703634:-HNSCGSVA_HALLMARK_PANCREAS_BETA_CELLSEER3.6582e-020.2285image
chrX:23702315-23703634:-KIRCGSVA_HALLMARK_HYPOXIAEER2.3950e-030.2947image
ENSG00000123130.15,ACOT9KIRPGSVA_HALLMARK_MITOTIC_SPINDLEEAG3.2592e-03-0.3355image
ENSG00000123130.15,ACOT9LUADGSVA_HALLMARK_FATTY_ACID_METABOLISMEAG1.2992e-020.2281image
chrX:23702315-23703634:-LUADGSVA_HALLMARK_FATTY_ACID_METABOLISMEER1.3910e-020.2298image
ENSG00000123130.15,ACOT9LUSCGSVA_HALLMARK_UNFOLDED_PROTEIN_RESPONSEEAG3.3032e-020.2092image
chrX:23702315-23703634:-LUSCGSVA_HALLMARK_UNFOLDED_PROTEIN_RESPONSEEER3.1287e-020.2124image
ENSG00000123130.15,ACOT9OVGSVA_HALLMARK_KRAS_SIGNALING_UPEAG2.0798e-030.2432image
chrX:23702315-23703634:-OVGSVA_HALLMARK_KRAS_SIGNALING_UPEER2.2436e-030.2422image
ENSG00000123130.15,ACOT9PAADGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKBEAG5.2628e-03-0.4136image
chrX:23702315-23703634:-PAADGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKBEER5.2628e-03-0.4136image
ENSG00000123130.15,ACOT9PCPGGSVA_HALLMARK_XENOBIOTIC_METABOLISMEAG4.7911e-04-0.7079image
ENSG00000123130.15,ACOT9PRADGSVA_HALLMARK_BILE_ACID_METABOLISMEAG3.6607e-03-0.2612image
ENSG00000123130.15,ACOT9SARCGSVA_HALLMARK_UV_RESPONSE_DNEAG2.8217e-030.2463image
chrX:23702315-23703634:-SARCGSVA_HALLMARK_UV_RESPONSE_DNEER3.2139e-030.2431image
ENSG00000123130.15,ACOT9SKCMGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEAG7.2117e-030.2186image
chrX:23702315-23703634:-SKCMGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEER8.2335e-030.2150image
ENSG00000123130.15,ACOT9STADGSVA_HALLMARK_DNA_REPAIREAG2.3682e-050.2814image
chrX:23702315-23703634:-STADGSVA_HALLMARK_DNA_REPAIREER7.5369e-060.3028image
ENSG00000123130.15,ACOT9THCAGSVA_HALLMARK_P53_PATHWAYEAG7.8298e-03-0.1668image
chrX:23702315-23703634:-THCAGSVA_HALLMARK_P53_PATHWAYEER7.7651e-03-0.1674image


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7. Enriched editing regions and drugs for ACOT9


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
chrX:23702315-23703634:-BLCAGDC0941EER2.9405e-030.4334image
ENSG00000123130.15,ACOT9BLCAGDC0941EAG3.3927e-030.4231image
chrX:23702315-23703634:-BRCABX.795EER1.6140e-040.2534image
ENSG00000123130.15,ACOT9BRCABX.795EAG8.2406e-050.2629image
ENSG00000123130.15,ACOT9CESCFTI.277EAG1.1588e-020.2940image
chrX:23702315-23703634:-CESCFTI.277EER1.5617e-020.2840image
ENSG00000123130.15,ACOT9COADMG.132EAG9.5832e-030.3952image
ENSG00000123130.15,ACOT9ESCAAICAREAG5.5431e-05-0.3778image
chrX:23702315-23703634:-ESCAAICAREER1.8683e-04-0.3568image
ENSG00000123130.15,ACOT9GBMMetforminEAG2.5148e-02-0.1934image
chrX:23702315-23703634:-GBMMetforminEER2.5124e-02-0.1934image
chrX:23702315-23703634:-HNSCLapatinibEER4.9225e-02-0.2179image
chrX:23702315-23703634:-KIRCBIRB.0796EER2.4661e-030.2938image
ENSG00000123130.15,ACOT9KIRCJNK.9LEAG2.8931e-070.4758image
ENSG00000123130.15,ACOT9KIRPGW.441756EAG1.7204e-020.2744image
ENSG00000123130.15,ACOT9LGGMethotrexateEAG4.1066e-040.2416image
chrX:23702315-23703634:-LGGMethotrexateEER4.1066e-040.2416image
ENSG00000123130.15,ACOT9LUSCAG.014699EAG2.0874e-020.2263image
chrX:23702315-23703634:-LUSCCI.1040EER1.5066e-02-0.2390image
ENSG00000123130.15,ACOT9MESOJNK.Inhibitor.VIIIEAG2.8695e-020.3598image
ENSG00000123130.15,ACOT9OVAZ628EAG1.6289e-03-0.2487image
chrX:23702315-23703634:-OVAZ628EER1.3065e-03-0.2543image
ENSG00000123130.15,ACOT9PCPGBIBW2992EAG4.2158e-030.6109image
ENSG00000123130.15,ACOT9PRADBicalutamideEAG4.0820e-040.3151image
chrX:23702315-23703634:-PRADJNJ.26854165EER5.7932e-030.2515image
ENSG00000123130.15,ACOT9SARCJNK.Inhibitor.VIIIEAG1.7465e-030.2578image
chrX:23702315-23703634:-SARCJNK.Inhibitor.VIIIEER2.0819e-030.2536image
ENSG00000123130.15,ACOT9SKCMCI.1040EAG2.4543e-02-0.1836image
chrX:23702315-23703634:-SKCMCI.1040EER2.4234e-02-0.1840image
ENSG00000123130.15,ACOT9STADCI.1040EAG8.1149e-05-0.2631image
chrX:23702315-23703634:-STADCI.1040EER3.2442e-04-0.2452image
chrX:23702315-23703634:-THCAAS601245EER2.4457e-040.2291image
ENSG00000123130.15,ACOT9THCAAS601245EAG2.5434e-040.2281image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType