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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: ZNF346 (ImmuneEditome ID:23567)

1. Gene summary of enriched editing regions for ZNF346

check button Gene summary
Gene informationGene symbol

ZNF346

Gene ID

23567

GeneSynonymsJAZ|Zfp346
GeneCytomap

5q35.2

GeneTypeprotein-coding
GeneDescriptionzinc finger protein 346|double-stranded RNA-binding zinc finger protein JAZ|just another zinc finger protein
GeneModificationdate20230517
UniprotIDQ9UL40;B7Z6Q2;B7Z6B6;B7Z4J8;B7Z4N4;D6RJ07
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr5:177045380-177048899:+ENST00000504600.1ENSG00000113761.10ZNF346ncRNA_intronicMIRc,AluSz,L1ME4c,AluSq2,AluSx,AluJr,(ATTT)n,AluY,AluSp,AluSx1,L1ME4achr5:177045380-177048899:+.alignment
chr5:177055088-177056225:+ENST00000358149.6ENSG00000113761.10ZNF346intronicAluSx1,AluSz,AluSxchr5:177055088-177056225:+.alignment
chr5:177055088-177056225:+ENST00000503039.1ENSG00000113761.10ZNF346intronicAluSx1,AluSz,AluSxchr5:177055088-177056225:+.alignment
chr5:177055088-177056225:+ENST00000503425.4ENSG00000113761.10ZNF346intronicAluSx1,AluSz,AluSxchr5:177055088-177056225:+.alignment
chr5:177055088-177056225:+ENST00000506693.4ENSG00000113761.10ZNF346intronicAluSx1,AluSz,AluSxchr5:177055088-177056225:+.alignment
chr5:177055088-177056225:+ENST00000508155.4ENSG00000113761.10ZNF346intronicAluSx1,AluSz,AluSxchr5:177055088-177056225:+.alignment
chr5:177055088-177056225:+ENST00000511834.4ENSG00000113761.10ZNF346intronicAluSx1,AluSz,AluSxchr5:177055088-177056225:+.alignment
chr5:177055088-177056225:+ENST00000512315.4ENSG00000113761.10ZNF346intronicAluSx1,AluSz,AluSxchr5:177055088-177056225:+.alignment
chr5:177055088-177056225:+ENST00000513587.4ENSG00000113761.10ZNF346intronicAluSx1,AluSz,AluSxchr5:177055088-177056225:+.alignment
chr5:177066586-177067934:+ENST00000503039.1ENSG00000113761.10ZNF346intronicAluJo,AluSx,AluSzchr5:177066586-177067934:+.alignment
chr5:177066586-177067934:+ENST00000512315.4ENSG00000113761.10ZNF346intronicAluJo,AluSx,AluSzchr5:177066586-177067934:+.alignment
chr5:177069188-177069973:+ENST00000503039.1ENSG00000113761.10ZNF346intronicL1ME3,AluJb,AluJo,AluSx1chr5:177069188-177069973:+.alignment
chr5:177069188-177069973:+ENST00000512315.4ENSG00000113761.10ZNF346intronicL1ME3,AluJb,AluJo,AluSx1chr5:177069188-177069973:+.alignment
chr5:177071230-177073500:+ENST00000503039.1ENSG00000113761.10ZNF346intronicAluJb,AluSz,FLAM_A,MLT1K,L2c,MIRb,AluYchr5:177071230-177073500:+.alignment
chr5:177071230-177073500:+ENST00000512315.4ENSG00000113761.10ZNF346intronicAluJb,AluSz,FLAM_A,MLT1K,L2c,MIRb,AluYchr5:177071230-177073500:+.alignment
chr5:177074492-177076969:+ENST00000503039.1ENSG00000113761.10ZNF346intronicMLT1K,SVA_B,AluY,AluSx1,AluJr,MER31A,MLT1F1,AluSq2,FLAM_Achr5:177074492-177076969:+.alignment
chr5:177074492-177076969:+ENST00000512315.4ENSG00000113761.10ZNF346intronicMLT1K,SVA_B,AluY,AluSx1,AluJr,MER31A,MLT1F1,AluSq2,FLAM_Achr5:177074492-177076969:+.alignment


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2. Tumor-specific enriched editing regions for ZNF346


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
ENSG00000113761.10,ZNF346THCAEAG3.7307e-02image


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
chr5:177055088-177056225:+STADEER1.5702e-039.0108e-033.0048e+06image
chr5:177066586-177067934:+STADEER2.0496e-022.9677e-025.8934e+02image

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3. Enriched editing regions and immune related genes for ZNF346


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark

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4. Enriched editing regions and immune related splicing for ZNF346


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000113761.10,ZNF346
ESCAEAGMEXENSG00000122359.13chr1080170799:80170915:80171612:80171881:80172600:80172700:80172806:80172869-0.26862.7454e-021.4085e-09-0.5177imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28B;LSM11;MBNL2;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RNF219;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZNF184ANXA11MonocytesGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
ENSG00000113761.10,ZNF346
ESCAEAGA3ENSG00000021355.8chr62836107:2836250:2835855:2835990:2835855:28360190.17644.4524e-027.5997e-140.6605imageNACIN1;ADAR;AUH;BCCIP;BUD13;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DKC1;EIF4A3;EIF4G2;ELAVL1;FAM120A;FBL;FMR1;FUS;FXR1;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28A;LIN28B;LSM11;MOV10;NONO;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;XRN2;YTHDC1;YTHDF1;YWHAG;ZNF184NAT_cells_CD4_naiveGSVA_HALLMARK_ESTROGEN_RESPONSE_EARLY
ENSG00000113761.10,ZNF346
ESCAEAGMEXENSG00000122359.13chr1080170799:80170915:80171612:80171846:80172600:80172700:80172806:80172869-0.26932.5414e-021.5152e-09-0.5206imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP4B;LIN28;LIN28B;LSM11;MBNL2;METTL3;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RNF219;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZNF184ANXA11T_cells_CD4_naiveGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY

More results



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5. Enriched editing regions and immune infiltration for ZNF346


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chr5:177069188-177069973:+BRCAEERNK_cells_activated3.2402e-030.5552image
chr5:177074492-177076969:+BRCAEERNK_cells_activated2.3672e-020.3406image
chr5:177066586-177067934:+ESCAEERT_cells_regulatory_(Tregs)9.5812e-03-0.4319image
chr5:177071230-177073500:+ESCAEERNK_cells_resting6.4729e-040.3491image
ENSG00000113761.10,ZNF346ESCAEAGNK_cells_activated2.1371e-02-0.2091image
ENSG00000113761.10,ZNF346GBMEAGDendritic_cells_activated1.4106e-020.3385image
ENSG00000113761.10,ZNF346HNSCEAGT_cells_regulatory_(Tregs)3.5268e-02-0.3924image
chr5:177045380-177048899:+KIRCEERPlasma_cells3.1557e-020.4000image
ENSG00000113761.10,ZNF346KIRPEAGT_cells_CD4_memory_activated1.0874e-030.5432image
chr5:177071230-177073500:+LAMLEERMast_cells_activated9.6658e-030.2932image
ENSG00000113761.10,ZNF346LGGEAGT_cells_regulatory_(Tregs)3.5141e-02-0.1305image
chr5:177045380-177048899:+OVEERT_cells_follicular_helper4.3931e-02-0.2633image
chr5:177055088-177056225:+OVEERT_cells_gamma_delta2.5592e-030.5984image
chr5:177066586-177067934:+OVEERNK_cells_activated1.3673e-020.3432image
chr5:177071230-177073500:+OVEERMast_cells_activated9.5137e-030.2462image
chr5:177074492-177076969:+OVEERNK_cells_activated1.1463e-02-0.4971image
ENSG00000113761.10,ZNF346OVEAGMast_cells_activated2.1882e-030.2428image
chr5:177045380-177048899:+PCPGEERB_cells_memory1.6347e-02-0.2317image
ENSG00000113761.10,ZNF346PCPGEAGNK_cells_activated9.4666e-03-0.2350image
ENSG00000113761.10,ZNF346PRADEAGT_cells_regulatory_(Tregs)4.7402e-030.3754image
ENSG00000113761.10,ZNF346SARCEAGPlasma_cells1.2431e-040.4790image
chr5:177045380-177048899:+STADEERT_cells_CD4_memory_activated9.7919e-040.2776image
chr5:177066586-177067934:+STADEERT_cells_CD4_memory_activated6.5055e-030.2930image
chr5:177069188-177069973:+STADEERT_cells_follicular_helper1.4524e-02-0.3222image
chr5:177071230-177073500:+STADEERT_cells_CD4_memory_resting1.5510e-02-0.1905image
chr5:177074492-177076969:+STADEERMast_cells_activated3.3321e-020.3416image
ENSG00000113761.10,ZNF346STADEAGT_cells_CD4_memory_activated7.9749e-040.2235image
chr5:177069188-177069973:+THCAEERDendritic_cells_resting3.5392e-020.4725image
ENSG00000113761.10,ZNF346THCAEAGEosinophils1.4430e-02-0.2035image
ENSG00000113761.10,ZNF346THYMEAGMonocytes3.0481e-020.3266image


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6. Enriched editing regions and immune gene sets for ZNF346


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot
chr5:177045380-177048899:+STADEER7.8067e-040.28276.3227e-030.23146.5526e-030.23041.4595e-020.2075image
chr5:177071230-177073500:+STADEER3.1525e-030.23134.3382e-020.15942.2802e-040.28662.7859e-020.1734image
ENSG00000113761.10,ZNF346STADEAG6.7571e-060.29691.4192e-040.25264.0118e-070.33232.5997e-020.1494image


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
ENSG00000113761.10,ZNF346BRCAGSVA_HALLMARK_ANDROGEN_RESPONSEEAG5.2062e-040.2192image
chr5:177045380-177048899:+BRCAGSVA_HALLMARK_NOTCH_SIGNALINGEER3.9420e-050.4046image
chr5:177074492-177076969:+BRCAGSVA_HALLMARK_P53_PATHWAYEER7.7221e-030.3964image
chr5:177069188-177069973:+BRCAGSVA_HALLMARK_ALLOGRAFT_REJECTIONEER3.4252e-020.4166image
ENSG00000113761.10,ZNF346CESCGSVA_HALLMARK_HEME_METABOLISMEAG5.4275e-040.5694image
chr5:177045380-177048899:+ESCAGSVA_HALLMARK_P53_PATHWAYEER1.1884e-030.3721image
chr5:177066586-177067934:+ESCAGSVA_HALLMARK_HYPOXIAEER1.2843e-020.4164image
chr5:177071230-177073500:+ESCAGSVA_HALLMARK_DNA_REPAIREER9.5869e-03-0.2688image
ENSG00000113761.10,ZNF346ESCAGSVA_HALLMARK_XENOBIOTIC_METABOLISMEAG2.1517e-020.2088image
chr5:177069188-177069973:+ESCAGSVA_HALLMARK_G2M_CHECKPOINTEER1.8230e-02-0.4777image
chr5:177074492-177076969:+GBMGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER1.4660e-020.4821image
ENSG00000113761.10,ZNF346HNSCGSVA_HALLMARK_E2F_TARGETSEAG5.5361e-03-0.5019image
ENSG00000113761.10,ZNF346KIRPGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG1.8831e-03-0.5209image
ENSG00000113761.10,ZNF346LAMLGSVA_HALLMARK_ANDROGEN_RESPONSEEAG1.6016e-030.2988image
chr5:177071230-177073500:+LAMLGSVA_HALLMARK_ANDROGEN_RESPONSEEER2.8374e-020.2499image
ENSG00000113761.10,ZNF346LUADGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKBEAG3.7300e-020.2868image
chr5:177071230-177073500:+OVGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEER9.7041e-030.2456image
chr5:177074492-177076969:+OVGSVA_HALLMARK_PROTEIN_SECRETIONEER2.3303e-020.4520image
chr5:177066586-177067934:+OVGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEER3.3870e-020.2977image
ENSG00000113761.10,ZNF346OVGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEAG3.8191e-030.2296image
chr5:177045380-177048899:+PCPGGSVA_HALLMARK_UV_RESPONSE_DNEER2.2479e-030.2923image
ENSG00000113761.10,ZNF346PCPGGSVA_HALLMARK_UV_RESPONSE_DNEAG1.0125e-030.2952image
ENSG00000113761.10,ZNF346SARCGSVA_HALLMARK_P53_PATHWAYEAG3.9125e-030.3701image
ENSG00000113761.10,ZNF346STADGSVA_HALLMARK_UV_RESPONSE_UPEAG6.0105e-040.2285image
chr5:177045380-177048899:+STADGSVA_HALLMARK_SPERMATOGENESISEER9.9878e-040.2772image
chr5:177071230-177073500:+STADGSVA_HALLMARK_UV_RESPONSE_UPEER2.3094e-020.1790image
chr5:177055088-177056225:+STADGSVA_HALLMARK_IL6_JAK_STAT3_SIGNALINGEER3.8742e-020.3412image
chr5:177074492-177076969:+STADGSVA_HALLMARK_SPERMATOGENESISEER2.5477e-020.3575image
chr5:177066586-177067934:+STADGSVA_HALLMARK_G2M_CHECKPOINTEER4.7041e-040.3712image
chr5:177069188-177069973:+STADGSVA_HALLMARK_ESTROGEN_RESPONSE_EARLYEER5.7461e-04-0.4421image
chr5:177069188-177069973:+THCAGSVA_HALLMARK_ANGIOGENESISEER1.1917e-030.6713image
ENSG00000113761.10,ZNF346THCAGSVA_HALLMARK_MYOGENESISEAG1.5615e-030.2613image
ENSG00000113761.10,ZNF346THYMGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEAG1.7141e-02-0.3577image


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7. Enriched editing regions and drugs for ZNF346


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
ENSG00000113761.10,ZNF346BLCABIRB.0796EAG4.4254e-030.4899image
ENSG00000113761.10,ZNF346BRCAABT.888EAG2.0805e-030.1950image
chr5:177069188-177069973:+BRCAGW843682XEER1.8618e-03-0.5808image
chr5:177074492-177076969:+BRCACCT018159EER4.9627e-02-0.2978image
chr5:177045380-177048899:+BRCAJNK.Inhibitor.VIIIEER4.1569e-040.3515image
ENSG00000113761.10,ZNF346CESCBIRB.0796EAG1.1850e-020.4329image
chr5:177066586-177067934:+ESCABMS.708163EER6.6838e-03-0.4500image
chr5:177045380-177048899:+ESCAAxitinibEER3.6048e-020.2475image
chr5:177071230-177073500:+ESCAAS601245EER1.0077e-020.2670image
ENSG00000113761.10,ZNF346ESCAAxitinibEAG1.6930e-030.2836image
chr5:177074492-177076969:+GBMDoxorubicinEER1.1457e-02-0.4972image
ENSG00000113761.10,ZNF346GBMGSK.650394EAG2.1012e-02-0.3194image
ENSG00000113761.10,ZNF346HNSCBexaroteneEAG8.2752e-03-0.4809image
ENSG00000113761.10,ZNF346KIRCAxitinibEAG6.0352e-030.3143image
ENSG00000113761.10,ZNF346KIRPAUY922EAG5.0558e-040.5720image
ENSG00000113761.10,ZNF346LAMLKU.55933EAG2.7436e-03-0.2842image
ENSG00000113761.10,ZNF346LGGAZD.2281EAG3.3799e-03-0.1808image
chr5:177045380-177048899:+OVAMG.706EER1.0603e-02-0.3304image
chr5:177071230-177073500:+OVCCT007093EER3.4349e-030.2767image
chr5:177055088-177056225:+OVFH535EER3.0687e-03-0.5896image
chr5:177074492-177076969:+OVFH535EER2.0655e-03-0.5864image
chr5:177066586-177067934:+OVCCT007093EER2.6436e-020.3108image
ENSG00000113761.10,ZNF346OVCI.1040EAG3.5602e-03-0.2313image
chr5:177045380-177048899:+PCPGDMOGEER2.1353e-03-0.2937image
ENSG00000113761.10,ZNF346PCPGBMS.536924EAG5.1017e-050.3596image
ENSG00000113761.10,ZNF346PRADCHIR.99021EAG2.5344e-02-0.3014image
ENSG00000113761.10,ZNF346SARCABT.263EAG5.2764e-06-0.5542image
ENSG00000113761.10,ZNF346SKCMDasatinibEAG6.8294e-04-0.3633image
ENSG00000113761.10,ZNF346STADBortezomibEAG1.6371e-04-0.2503image
chr5:177045380-177048899:+STADGemcitabineEER9.6602e-03-0.2196image
chr5:177069188-177069973:+STADBicalutamideEER3.2716e-040.4592image
chr5:177071230-177073500:+STADBortezomibEER4.2844e-03-0.2240image
chr5:177066586-177067934:+STADAG.014699EER7.8923e-040.3573image
chr5:177055088-177056225:+STADAUY922EER2.5387e-03-0.4817image
chr5:177069188-177069973:+THCAGW.441756EER2.5130e-020.4989image
ENSG00000113761.10,ZNF346THCABexaroteneEAG6.2195e-03-0.2270image
ENSG00000113761.10,ZNF346THYMElesclomolEAG1.5247e-020.3636image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType