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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: TARDBP (ImmuneEditome ID:23435)

1. Gene summary of enriched editing regions for TARDBP

check button Gene summary
Gene informationGene symbol

TARDBP

Gene ID

23435

GeneSynonymsALS10|TDP-43
GeneCytomap

1p36.22

GeneTypeprotein-coding
GeneDescriptionTAR DNA-binding protein 43|TAR DNA-binding protein-43
GeneModificationdate20230528
UniprotIDG3V162;Q13148;B1AKP7;A0A0A0N0M3;A0A0A0MSV7;A0A087WZC9;K7EN94;A0A024R4E2;K7EJM5;A0A087WYY0;A0A087X260;K7EJ99;A0A087WX29;A0A087WXV3
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr1:11020679-11021927:+ENST00000240185.6ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000315091.6ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000439080.5ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000472476.4ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000473869.4ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000477447.5ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000610369.3ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000611136.3ENSG00000277726.3TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000611963.3ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000614494.1ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000614757.3ENSG00000277726.3TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000616545.3ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000617172.3ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000619555.3ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000620632.3ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000621715.3ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000621790.3ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000622057.3ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment
chr1:11020679-11021927:+ENST00000629725.1ENSG00000120948.14TARDBPintronicAluSq2,AluSc,AluJr,AluSxchr1:11020679-11021927:+.alignment


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2. Tumor-specific enriched editing regions for TARDBP


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chr1:11020679-11021927:+KIRCEER1.0449e-02image
ENSG00000120948.14,TARDBPKIRCEAG1.9414e-02image
ENSG00000277726.3,TARDBPKIRCEAG1.9414e-02image
chr1:11020679-11021927:+THCAEER2.3956e-03image
ENSG00000120948.14,TARDBPTHCAEAG9.9332e-04image
ENSG00000277726.3,TARDBPTHCAEAG9.9332e-04image


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
ENSG00000120948.14,TARDBPMESOPathEAG2.4064e-043.3535e-04-0.6291image
ENSG00000277726.3,TARDBPMESOPathEAG2.4064e-043.3535e-04-0.6291image
chr1:11020679-11021927:+MESOPathEER2.3708e-043.3533e-04-0.6291image


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
ENSG00000120948.14,TARDBPLUADEAG2.7854e-024.2846e-025.7443e+00image
ENSG00000277726.3,TARDBPLUADEAG2.7854e-024.2846e-025.7443e+00image
ENSG00000120948.14,TARDBPUCSEAG1.9333e-026.0966e-031.0040e+05image
ENSG00000277726.3,TARDBPUCSEAG1.9333e-026.0966e-031.0040e+05image

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3. Enriched editing regions and immune related genes for TARDBP


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:11020679-11021927:+ESCAEERENSG00000100628,ASB20.30233.5497e-024.9570e-070.4211imageTARDBPFUSNAMast_cells_restingGSVA_HALLMARK_MYOGENESIS
chr1:11020679-11021927:+ESCAEERENSG00000198832,SELM0.28884.7585e-023.8160e-070.4249imageNFUSNAMacrophages_M2GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

More results



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4. Enriched editing regions and immune related splicing for TARDBP


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr1:11020679-11021927:+
ESCAEERMEXENSG00000197111.11chr1253462513:53462567:53464764:53465031:53465931:53465972:53467220:53467285-0.32763.4161e-021.5246e-06-0.4043imageTARDBPFUSPCBP2NeutrophilsGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSE
ENSG00000120948.14,TARDBP
ESCAEAGESENSG00000197111.11chr1253462513:53462567:53464764:53464852:53465931:53465972-0.32963.2885e-021.7083e-06-0.4026imageTARDBPACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NCBP3;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184PCBP2NeutrophilsGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSE
ENSG00000277726.3,TARDBP
ESCAEAGESENSG00000197111.11chr1253462513:53462567:53464764:53464852:53465931:53465972-0.32963.2885e-021.7083e-06-0.4026imageTARDBPACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NCBP3;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184PCBP2NeutrophilsGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSE
chr1:11020679-11021927:+
ESCAEERESENSG00000197111.11chr1253462513:53462567:53464764:53464852:53465931:53465972-0.32683.0224e-021.6353e-06-0.4032imageTARDBPFUSPCBP2NeutrophilsGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSE
chr1:11020679-11021927:+
ESCAEERESENSG00000197111.11chr1253462513:53462567:53464764:53464852:53467220:53467285-0.35779.4489e-037.7967e-07-0.4144imageTARDBPFUSPCBP2NeutrophilsGSVA_HALLMARK_ALLOGRAFT_REJECTION
ENSG00000120948.14,TARDBP
ESCAEAGMEXENSG00000197111.11chr1253462513:53462567:53464764:53465031:53465931:53465972:53467220:53467285-0.33033.7282e-021.5979e-06-0.4036imageTARDBPACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NCBP3;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184PCBP2NeutrophilsGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSE
ENSG00000277726.3,TARDBP
ESCAEAGMEXENSG00000197111.11chr1253462513:53462567:53464764:53465031:53465931:53465972:53467220:53467285-0.33033.7282e-021.5979e-06-0.4036imageTARDBPACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NCBP3;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184PCBP2NeutrophilsGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSE
ENSG00000120948.14,TARDBP
ESCAEAGESENSG00000197111.11chr1253462513:53462567:53464764:53464852:53467220:53467285-0.35911.0518e-028.5612e-07-0.4131imageTARDBPACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NCBP3;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184PCBP2NeutrophilsGSVA_HALLMARK_ALLOGRAFT_REJECTION
ENSG00000277726.3,TARDBP
ESCAEAGESENSG00000197111.11chr1253462513:53462567:53464764:53464852:53467220:53467285-0.35911.0518e-028.5612e-07-0.4131imageTARDBPACIN1;ADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CBX7;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MBNL2;MOV10;MSI2;NCBP3;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RC3H1;RNF219;RTCB;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF10;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184PCBP2NeutrophilsGSVA_HALLMARK_ALLOGRAFT_REJECTION

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5. Enriched editing regions and immune infiltration for TARDBP


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
ENSG00000120948.14,TARDBPACCEAGMast_cells_resting1.7880e-020.4038image
ENSG00000277726.3,TARDBPACCEAGMast_cells_resting1.7880e-020.4038image
chr1:11020679-11021927:+BLCAEERMacrophages_M16.5394e-050.2596image
ENSG00000120948.14,TARDBPBLCAEAGMacrophages_M13.1577e-050.2690image
ENSG00000277726.3,TARDBPBLCAEAGMacrophages_M13.1577e-050.2690image
ENSG00000120948.14,TARDBPBRCAEAGNK_cells_activated4.4021e-020.0822image
ENSG00000277726.3,TARDBPBRCAEAGNK_cells_activated4.4021e-020.0822image
chr1:11020679-11021927:+CESCEERT_cells_CD4_naive3.1062e-02-0.1738image
ENSG00000120948.14,TARDBPCESCEAGT_cells_CD4_naive2.7853e-02-0.1767image
ENSG00000277726.3,TARDBPCESCEAGT_cells_CD4_naive2.7853e-02-0.1767image
chr1:11020679-11021927:+COADEERDendritic_cells_activated5.4284e-040.3633image
ENSG00000120948.14,TARDBPCOADEAGDendritic_cells_activated4.5668e-040.3619image
ENSG00000277726.3,TARDBPCOADEAGDendritic_cells_activated4.5668e-040.3619image
chr1:11020679-11021927:+ESCAEERT_cells_gamma_delta3.3101e-040.3078image
ENSG00000120948.14,TARDBPESCAEAGT_cells_gamma_delta3.3093e-040.3078image
ENSG00000277726.3,TARDBPESCAEAGT_cells_gamma_delta3.3093e-040.3078image
chr1:11020679-11021927:+GBMEERNeutrophils2.0582e-020.2268image
ENSG00000120948.14,TARDBPGBMEAGNeutrophils2.0369e-020.2272image
ENSG00000277726.3,TARDBPGBMEAGNeutrophils2.0369e-020.2272image
chr1:11020679-11021927:+HNSCEERPlasma_cells1.2205e-02-0.1761image
ENSG00000120948.14,TARDBPHNSCEAGPlasma_cells9.7793e-03-0.1801image
ENSG00000277726.3,TARDBPHNSCEAGPlasma_cells9.7793e-03-0.1801image
ENSG00000120948.14,TARDBPKICHEAGB_cells_memory4.6602e-02-0.4498image
ENSG00000277726.3,TARDBPKICHEAGB_cells_memory4.6602e-02-0.4498image
chr1:11020679-11021927:+KIRCEERT_cells_CD4_naive4.9919e-040.2989image
ENSG00000120948.14,TARDBPKIRCEAGT_cells_CD4_naive4.1400e-040.3018image
ENSG00000277726.3,TARDBPKIRCEAGT_cells_CD4_naive4.1400e-040.3018image
ENSG00000120948.14,TARDBPLAMLEAGT_cells_regulatory_(Tregs)8.3057e-040.5693image
ENSG00000277726.3,TARDBPLAMLEAGT_cells_regulatory_(Tregs)8.3057e-040.5693image
chr1:11020679-11021927:+LIHCEERMast_cells_resting1.8089e-020.1494image
ENSG00000120948.14,TARDBPLIHCEAGB_cells_naive1.8665e-02-0.1487image
ENSG00000277726.3,TARDBPLIHCEAGB_cells_naive1.8665e-02-0.1487image
chr1:11020679-11021927:+LUADEERB_cells_naive1.0083e-02-0.1469image
ENSG00000120948.14,TARDBPLUADEAGB_cells_naive1.0504e-02-0.1454image
ENSG00000277726.3,TARDBPLUADEAGB_cells_naive1.0504e-02-0.1454image
chr1:11020679-11021927:+LUSCEERDendritic_cells_resting6.3603e-03-0.1497image
ENSG00000120948.14,TARDBPLUSCEAGDendritic_cells_resting5.2287e-03-0.1525image
ENSG00000277726.3,TARDBPLUSCEAGDendritic_cells_resting5.2287e-03-0.1525image
chr1:11020679-11021927:+MESOEEREosinophils1.8418e-020.4587image
ENSG00000120948.14,TARDBPMESOEAGEosinophils1.8640e-020.4580image
ENSG00000277726.3,TARDBPMESOEAGEosinophils1.8640e-020.4580image
chr1:11020679-11021927:+PCPGEERMacrophages_M13.5273e-030.3245image
ENSG00000120948.14,TARDBPPCPGEAGMacrophages_M13.4432e-030.3253image
ENSG00000277726.3,TARDBPPCPGEAGMacrophages_M13.4432e-030.3253image
ENSG00000120948.14,TARDBPPRADEAGPlasma_cells2.2000e-02-0.1810image
ENSG00000277726.3,TARDBPPRADEAGPlasma_cells2.2000e-02-0.1810image
ENSG00000120948.14,TARDBPREADEAGDendritic_cells_resting1.6126e-020.4356image
ENSG00000277726.3,TARDBPREADEAGDendritic_cells_resting1.6126e-020.4356image
chr1:11020679-11021927:+SKCMEERT_cells_CD83.4412e-030.1851image
ENSG00000120948.14,TARDBPSKCMEAGT_cells_CD86.4801e-030.1721image
ENSG00000277726.3,TARDBPSKCMEAGT_cells_CD86.4801e-030.1721image
chr1:11020679-11021927:+STADEERT_cells_CD82.1458e-020.1598image
ENSG00000120948.14,TARDBPSTADEAGT_cells_CD81.9234e-020.1626image
ENSG00000277726.3,TARDBPSTADEAGT_cells_CD81.9234e-020.1626image
ENSG00000120948.14,TARDBPTGCTEAGMacrophages_M21.7616e-02-0.3344image
ENSG00000277726.3,TARDBPTGCTEAGMacrophages_M21.7616e-02-0.3344image
chr1:11020679-11021927:+THCAEERT_cells_gamma_delta4.1819e-02-0.1174image
ENSG00000120948.14,TARDBPTHCAEAGT_cells_gamma_delta3.4950e-02-0.1208image
ENSG00000277726.3,TARDBPTHCAEAGT_cells_gamma_delta3.4950e-02-0.1208image
ENSG00000120948.14,TARDBPTHYMEAGT_cells_CD4_memory_resting2.0506e-020.3118image
ENSG00000277726.3,TARDBPTHYMEAGT_cells_CD4_memory_resting2.0506e-020.3118image
chr1:11020679-11021927:+UCECEERT_cells_regulatory_(Tregs)2.2482e-030.2950image
ENSG00000120948.14,TARDBPUCECEAGT_cells_regulatory_(Tregs)2.0790e-030.2958image
ENSG00000277726.3,TARDBPUCECEAGT_cells_regulatory_(Tregs)2.0790e-030.2958image


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6. Enriched editing regions and immune gene sets for TARDBP


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot
ENSG00000277726.3,TARDBPBLCAEAG3.6025e-02image1.8417e-020.1543image
ENSG00000120948.14,TARDBPBLCAEAG3.6025e-02image1.8417e-020.1543image


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
ENSG00000277726.3,TARDBPACCGSVA_HALLMARK_DNA_REPAIREAG1.6856e-03-0.5184image
ENSG00000120948.14,TARDBPACCGSVA_HALLMARK_DNA_REPAIREAG1.6856e-03-0.5184image
ENSG00000120948.14,TARDBPBLCAGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG3.1075e-060.3001image
chr1:11020679-11021927:+BLCAGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER3.3395e-060.3004image
ENSG00000277726.3,TARDBPBLCAGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG3.1075e-060.3001image
ENSG00000120948.14,TARDBPBRCAGSVA_HALLMARK_DNA_REPAIREAG2.3551e-020.0924image
chr1:11020679-11021927:+BRCAGSVA_HALLMARK_DNA_REPAIREER2.9313e-020.0894image
ENSG00000277726.3,TARDBPBRCAGSVA_HALLMARK_DNA_REPAIREAG2.3551e-020.0924image
ENSG00000277726.3,TARDBPCESCGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG3.6645e-03-0.2321image
chr1:11020679-11021927:+CESCGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER4.3910e-03-0.2284image
ENSG00000120948.14,TARDBPCESCGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG3.6645e-03-0.2321image
ENSG00000277726.3,TARDBPCOADGSVA_HALLMARK_MITOTIC_SPINDLEEAG8.9172e-04-0.3443image
ENSG00000120948.14,TARDBPCOADGSVA_HALLMARK_MITOTIC_SPINDLEEAG8.9172e-04-0.3443image
chr1:11020679-11021927:+COADGSVA_HALLMARK_MITOTIC_SPINDLEEER5.5109e-04-0.3629image
ENSG00000277726.3,TARDBPESCAGSVA_HALLMARK_MYOGENESISEAG1.7040e-030.2706image
chr1:11020679-11021927:+ESCAGSVA_HALLMARK_MYOGENESISEER1.6624e-030.2712image
ENSG00000120948.14,TARDBPESCAGSVA_HALLMARK_MYOGENESISEAG1.7040e-030.2706image
ENSG00000120948.14,TARDBPGBMGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEAG1.5755e-02-0.2363image
ENSG00000277726.3,TARDBPGBMGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEAG1.5755e-02-0.2363image
chr1:11020679-11021927:+GBMGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEER1.4089e-02-0.2401image
ENSG00000277726.3,TARDBPHNSCGSVA_HALLMARK_PANCREAS_BETA_CELLSEAG2.9376e-030.2067image
ENSG00000120948.14,TARDBPHNSCGSVA_HALLMARK_PANCREAS_BETA_CELLSEAG2.9376e-030.2067image
chr1:11020679-11021927:+HNSCGSVA_HALLMARK_PANCREAS_BETA_CELLSEER4.6256e-030.1985image
ENSG00000277726.3,TARDBPLAMLGSVA_HALLMARK_MITOTIC_SPINDLEEAG2.6854e-03-0.5205image
ENSG00000120948.14,TARDBPLAMLGSVA_HALLMARK_MITOTIC_SPINDLEEAG2.6854e-03-0.5205image
ENSG00000277726.3,TARDBPLGGGSVA_HALLMARK_MITOTIC_SPINDLEEAG9.9968e-03-0.1809image
ENSG00000120948.14,TARDBPLGGGSVA_HALLMARK_MITOTIC_SPINDLEEAG9.9968e-03-0.1809image
chr1:11020679-11021927:+LIHCGSVA_HALLMARK_MITOTIC_SPINDLEEER4.5915e-020.1264image
ENSG00000277726.3,TARDBPLIHCGSVA_HALLMARK_MITOTIC_SPINDLEEAG4.6720e-020.1259image
ENSG00000120948.14,TARDBPLIHCGSVA_HALLMARK_MITOTIC_SPINDLEEAG4.6720e-020.1259image
ENSG00000120948.14,TARDBPLUSCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG1.5450e-030.1726image
chr1:11020679-11021927:+LUSCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.6261e-030.1726image
ENSG00000277726.3,TARDBPLUSCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG1.5450e-030.1726image
ENSG00000120948.14,TARDBPOVGSVA_HALLMARK_XENOBIOTIC_METABOLISMEAG1.6469e-020.1729image
chr1:11020679-11021927:+OVGSVA_HALLMARK_XENOBIOTIC_METABOLISMEER1.5610e-020.1743image
ENSG00000277726.3,TARDBPOVGSVA_HALLMARK_XENOBIOTIC_METABOLISMEAG1.6469e-020.1729image
ENSG00000277726.3,TARDBPPCPGGSVA_HALLMARK_NOTCH_SIGNALINGEAG3.4011e-03-0.3257image
ENSG00000120948.14,TARDBPPCPGGSVA_HALLMARK_NOTCH_SIGNALINGEAG3.4011e-03-0.3257image
chr1:11020679-11021927:+PCPGGSVA_HALLMARK_NOTCH_SIGNALINGEER3.2831e-03-0.3268image
ENSG00000277726.3,TARDBPREADGSVA_HALLMARK_G2M_CHECKPOINTEAG3.5020e-03-0.5162image
ENSG00000120948.14,TARDBPREADGSVA_HALLMARK_G2M_CHECKPOINTEAG3.5020e-03-0.5162image
ENSG00000277726.3,TARDBPSKCMGSVA_HALLMARK_ALLOGRAFT_REJECTIONEAG5.8448e-030.1742image
ENSG00000120948.14,TARDBPSKCMGSVA_HALLMARK_ALLOGRAFT_REJECTIONEAG5.8448e-030.1742image
chr1:11020679-11021927:+SKCMGSVA_HALLMARK_ALLOGRAFT_REJECTIONEER1.5697e-030.1997image
chr1:11020679-11021927:+STADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.7978e-020.1643image
ENSG00000277726.3,TARDBPSTADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG1.6884e-020.1659image
ENSG00000120948.14,TARDBPSTADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG1.6884e-020.1659image
chr1:11020679-11021927:+THCAGSVA_HALLMARK_G2M_CHECKPOINTEER2.3507e-030.1747image
ENSG00000277726.3,TARDBPTHCAGSVA_HALLMARK_G2M_CHECKPOINTEAG1.9020e-030.1771image
ENSG00000120948.14,TARDBPTHCAGSVA_HALLMARK_G2M_CHECKPOINTEAG1.9020e-030.1771image
ENSG00000277726.3,TARDBPUCECGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG1.8064e-020.2293image
ENSG00000120948.14,TARDBPUCECGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG1.8064e-020.2293image
chr1:11020679-11021927:+UCECGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.6030e-020.2345image


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7. Enriched editing regions and drugs for TARDBP


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
ENSG00000120948.14,TARDBPACCImatinibEAG1.1290e-03-0.5345image
ENSG00000277726.3,TARDBPACCImatinibEAG1.1290e-03-0.5345image
ENSG00000277726.3,TARDBPBLCAKU.55933EAG5.2563e-04-0.2254image
ENSG00000120948.14,TARDBPBLCAKU.55933EAG5.2563e-04-0.2254image
chr1:11020679-11021927:+BLCAKU.55933EER2.8579e-04-0.2366image
ENSG00000277726.3,TARDBPBRCACyclopamineEAG8.7566e-03-0.1073image
ENSG00000120948.14,TARDBPBRCACyclopamineEAG8.7566e-03-0.1073image
chr1:11020679-11021927:+BRCACyclopamineEER8.7127e-03-0.1079image
ENSG00000120948.14,TARDBPCESCIPA.3EAG3.5223e-030.2330image
ENSG00000277726.3,TARDBPCESCIPA.3EAG3.5223e-030.2330image
chr1:11020679-11021927:+CESCIPA.3EER4.4163e-030.2282image
ENSG00000277726.3,TARDBPCOADGW843682XEAG1.1316e-030.3378image
ENSG00000120948.14,TARDBPCOADGW843682XEAG1.1316e-030.3378image
chr1:11020679-11021927:+COADGW843682XEER1.0730e-030.3448image
ENSG00000277726.3,TARDBPESCACGP.60474EAG6.0783e-05-0.3417image
ENSG00000120948.14,TARDBPESCACGP.60474EAG6.0783e-05-0.3417image
chr1:11020679-11021927:+ESCACGP.60474EER5.8989e-05-0.3423image
ENSG00000277726.3,TARDBPGBMCCT018159EAG3.4246e-020.2078image
ENSG00000120948.14,TARDBPGBMCCT018159EAG3.4246e-020.2078image
chr1:11020679-11021927:+GBMCCT018159EER3.0542e-020.2122image
chr1:11020679-11021927:+HNSCA.770041EER3.7553e-04-0.2485image
ENSG00000120948.14,TARDBPHNSCA.770041EAG2.3121e-04-0.2551image
ENSG00000277726.3,TARDBPHNSCA.770041EAG2.3121e-04-0.2551image
ENSG00000120948.14,TARDBPKIRPLenalidomideEAG4.5827e-02-0.1953image
ENSG00000277726.3,TARDBPKIRPLenalidomideEAG4.5827e-02-0.1953image
chr1:11020679-11021927:+KIRPBIRB.0796EER3.7833e-02-0.2030image
ENSG00000277726.3,TARDBPLAMLLenalidomideEAG5.9943e-030.4824image
ENSG00000120948.14,TARDBPLAMLLenalidomideEAG5.9943e-030.4824image
ENSG00000120948.14,TARDBPLGGAZD6482EAG5.8851e-040.2398image
ENSG00000277726.3,TARDBPLGGAZD6482EAG5.8851e-040.2398image
ENSG00000277726.3,TARDBPLIHCAZ628EAG2.7781e-020.1397image
ENSG00000120948.14,TARDBPLIHCAZ628EAG2.7781e-020.1397image
chr1:11020679-11021927:+LIHCAZ628EER2.7515e-020.1400image
ENSG00000277726.3,TARDBPLUSCCyclopamineEAG3.8753e-03-0.1579image
chr1:11020679-11021927:+LUSCCyclopamineEER2.9240e-03-0.1633image
ENSG00000120948.14,TARDBPLUSCCyclopamineEAG3.8753e-03-0.1579image
chr1:11020679-11021927:+MESOGDC.0449EER2.7585e-020.4319image
ENSG00000120948.14,TARDBPMESOGDC.0449EAG2.9293e-020.4277image
ENSG00000277726.3,TARDBPMESOGDC.0449EAG2.9293e-020.4277image
chr1:11020679-11021927:+OVCI.1040EER2.1191e-03-0.2205image
ENSG00000120948.14,TARDBPOVCI.1040EAG2.5240e-03-0.2168image
ENSG00000277726.3,TARDBPOVCI.1040EAG2.5240e-03-0.2168image
ENSG00000120948.14,TARDBPPAADElesclomolEAG3.4458e-020.2076image
ENSG00000277726.3,TARDBPPAADElesclomolEAG3.4458e-020.2076image
ENSG00000120948.14,TARDBPPCPGAKT.inhibitor.VIIIEAG1.3084e-030.3554image
chr1:11020679-11021927:+PCPGAKT.inhibitor.VIIIEER1.2915e-030.3558image
ENSG00000277726.3,TARDBPPCPGAKT.inhibitor.VIIIEAG1.3084e-030.3554image
ENSG00000120948.14,TARDBPPRADAZD.0530EAG1.1669e-020.2021image
ENSG00000277726.3,TARDBPPRADAZD.0530EAG1.1669e-020.2021image
ENSG00000277726.3,TARDBPREADCI.1040EAG2.2584e-02-0.4150image
ENSG00000120948.14,TARDBPREADCI.1040EAG2.2584e-02-0.4150image
ENSG00000120948.14,TARDBPSARCCCT018159EAG1.0432e-030.3141image
ENSG00000277726.3,TARDBPSARCCCT018159EAG1.0432e-030.3141image
ENSG00000277726.3,TARDBPSKCMA.443654EAG9.9761e-050.2441image
ENSG00000120948.14,TARDBPSKCMA.443654EAG9.9761e-050.2441image
chr1:11020679-11021927:+SKCMA.443654EER1.1390e-040.2426image
chr1:11020679-11021927:+STADCEP.701EER1.4442e-02-0.1698image
ENSG00000120948.14,TARDBPSTADCEP.701EAG1.1238e-02-0.1759image
ENSG00000277726.3,TARDBPSTADCEP.701EAG1.1238e-02-0.1759image
ENSG00000120948.14,TARDBPTGCTBMS.754807EAG6.1083e-030.3826image
ENSG00000277726.3,TARDBPTGCTBMS.754807EAG6.1083e-030.3826image
chr1:11020679-11021927:+THCAABT.263EER3.8643e-030.1660image
ENSG00000277726.3,TARDBPTHCAABT.263EAG7.1495e-030.1537image
ENSG00000120948.14,TARDBPTHCAABT.263EAG7.1495e-030.1537image
ENSG00000120948.14,TARDBPTHYMCCT018159EAG2.1218e-03-0.4057image
ENSG00000277726.3,TARDBPTHYMCCT018159EAG2.1218e-03-0.4057image
ENSG00000120948.14,TARDBPUCECAP.24534EAG1.7702e-02-0.2300image
ENSG00000277726.3,TARDBPUCECAP.24534EAG1.7702e-02-0.2300image
chr1:11020679-11021927:+UCECAP.24534EER1.8419e-02-0.2297image
ENSG00000120948.14,TARDBPUCSCMKEAG7.2142e-030.4236image
ENSG00000277726.3,TARDBPUCSCMKEAG7.2142e-030.4236image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType