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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: AGO3 (ImmuneEditome ID:192669)

1. Gene summary of enriched editing regions for AGO3

check button Gene summary
Gene informationGene symbol

AGO3

Gene ID

192669

GeneSynonymsEIF2C3
GeneCytomap

1p34.3

GeneTypeprotein-coding
GeneDescriptionprotein argonaute-3|argonaute 3, RISC catalytic component|eukaryotic translation initiation factor 2C, 3|hAgo3
GeneModificationdate20230518
UniprotIDQ9H9G7;Q5TA56;A0A0U1RR19
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr1:35978323-35979302:+ENST00000246314.9ENSG00000126070.17AGO3intronicL1MC4a,AluSq2,AluYchr1:35978323-35979302:+.alignment
chr1:35978323-35979302:+ENST00000324350.8ENSG00000126070.17AGO3intronicL1MC4a,AluSq2,AluYchr1:35978323-35979302:+.alignment
chr1:35978323-35979302:+ENST00000373191.7ENSG00000126070.17AGO3intronicL1MC4a,AluSq2,AluYchr1:35978323-35979302:+.alignment
chr1:35978323-35979302:+ENST00000397828.3ENSG00000126070.17AGO3intronicL1MC4a,AluSq2,AluYchr1:35978323-35979302:+.alignment
chr1:36040762-36042395:+ENST00000246314.9ENSG00000126070.17AGO3intronicMIR,AluY,AluSzchr1:36040762-36042395:+.alignment
chr1:36040762-36042395:+ENST00000373191.7ENSG00000126070.17AGO3intronicMIR,AluY,AluSzchr1:36040762-36042395:+.alignment
chr1:36043887-36044346:+ENST00000471099.1ENSG00000126070.17AGO3ncRNA_intronicFLAM_C,AluJr,(AG)nchr1:36043887-36044346:+.alignment
chr1:36045376-36045691:+ENST00000471099.1ENSG00000126070.17AGO3ncRNA_intronicAluSx1,AluSq2chr1:36045376-36045691:+.alignment
chr1:36047044-36049446:+ENST00000471099.1ENSG00000126070.17AGO3ncRNA_intronicAluSp,L1MA5,L1PA16,(TCAA)n,AluJo,AluJb,AluScchr1:36047044-36049446:+.alignment
chr1:36050878-36051636:+ENST00000471099.1ENSG00000126070.17AGO3ncRNA_intronicL1MA5,AluJo,AluJr4,AluSzchr1:36050878-36051636:+.alignment
chr1:36056797-36057972:+ENST00000373191.7ENSG00000126070.17AGO3UTR3(TTCTTT)n,AluSq2,AluSc,(AT)nchr1:36056797-36057972:+.alignment
chr1:36063774-36070089:+ENST00000373191.7ENSG00000126070.17AGO3UTR3FLAM_A,MIRc,AluSq2,AluSg,(CA)n,AluJo,AluSx,AluSc,AluSx1,AluSq,MamRep434chr1:36063774-36070089:+.alignment


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2. Tumor-specific enriched editing regions for AGO3


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chr1:36063774-36070089:+BRCAEER1.2296e-04image
ENSG00000126070.17,AGO3BRCAEAG5.8463e-04image
chr1:36063774-36070089:+LUSCEER5.1961e-03image
ENSG00000126070.17,AGO3LUSCEAG1.1080e-02image
chr1:36063774-36070089:+THCAEER8.7314e-04image
ENSG00000126070.17,AGO3THCAEAG1.4270e-03image


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
chr1:36056797-36057972:+BRCAPathEER4.4264e-021.3068e-020.5202image
ENSG00000126070.17,AGO3ESCAPathEAG2.9310e-024.3123e-030.2557image
chr1:36063774-36070089:+OVCliEER3.7572e-022.3200e-02-0.1660image
ENSG00000126070.17,AGO3PAADPathEAG2.1674e-022.1674e-02-0.3454image
chr1:36063774-36070089:+PAADPathEER2.9481e-022.9481e-02-0.3323image


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot

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3. Enriched editing regions and immune related genes for AGO3


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark

More results



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4. Enriched editing regions and immune related splicing for AGO3


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000126070.17,AGO3
ESCAEAGMEXENSG00000139722.2chr12122870889:122871061:122871211:122871396:122879328:122879505:122895951:122896127-0.35779.3448e-033.1735e-06-0.4139imageNACIN1;ADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;ELAVL3;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR2;HNRNPA1;HNRNPC;HNRNPD;HNRNPK;HNRNPL;HNRNPM;HNRNPU;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHSRP;LARP7;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI1;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM47;RBM5;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZC3H7B;ZNF184NAT_cells_gamma_deltaGSVA_HALLMARK_HEDGEHOG_SIGNALING

More results



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5. Enriched editing regions and immune infiltration for AGO3


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chr1:36063774-36070089:+BLCAEERMacrophages_M12.2933e-030.3718image
ENSG00000126070.17,AGO3BLCAEAGMacrophages_M11.1683e-040.4472image
chr1:36063774-36070089:+BRCAEERMonocytes2.6800e-02-0.0916image
chr1:36063774-36070089:+CESCEERDendritic_cells_resting1.0006e-030.3959image
ENSG00000126070.17,AGO3CESCEAGDendritic_cells_resting1.2701e-030.3856image
chr1:36063774-36070089:+COADEERDendritic_cells_activated3.6628e-050.5918image
ENSG00000126070.17,AGO3COADEAGDendritic_cells_activated5.4721e-050.5752image
chr1:36047044-36049446:+ESCAEERMacrophages_M12.7702e-020.4019image
ENSG00000126070.17,AGO3ESCAEAGB_cells_memory1.4352e-02-0.2073image
chr1:36063774-36070089:+GBMEERT_cells_follicular_helper2.3313e-02-0.2152image
ENSG00000126070.17,AGO3GBMEAGT_cells_follicular_helper2.3316e-02-0.2152image
chr1:36063774-36070089:+HNSCEERT_cells_CD4_naive2.1545e-020.2332image
ENSG00000126070.17,AGO3HNSCEAGT_cells_CD4_naive2.1012e-020.2283image
chr1:36063774-36070089:+KIRPEERNK_cells_resting1.4592e-030.3419image
ENSG00000126070.17,AGO3KIRPEAGNK_cells_resting1.7396e-030.3348image
chr1:36063774-36070089:+LGGEERMacrophages_M25.1824e-030.1367image
ENSG00000126070.17,AGO3LGGEAGMacrophages_M24.3988e-030.1392image
chr1:36063774-36070089:+LUADEEREosinophils3.5424e-02-0.1696image
ENSG00000126070.17,AGO3LUADEAGEosinophils1.5499e-02-0.1917image
chr1:36063774-36070089:+LUSCEEREosinophils2.2917e-02-0.1964image
ENSG00000126070.17,AGO3LUSCEAGEosinophils1.2387e-02-0.2132image
chr1:36063774-36070089:+MESOEERT_cells_follicular_helper9.4191e-030.4992image
ENSG00000126070.17,AGO3MESOEAGT_cells_follicular_helper2.1225e-020.4412image
chr1:36047044-36049446:+OVEERT_cells_CD4_memory_activated1.2522e-020.4656image
chr1:36063774-36070089:+OVEERB_cells_memory3.5645e-02-0.1711image
ENSG00000126070.17,AGO3OVEAGT_cells_CD4_memory_activated2.6595e-030.2311image
chr1:36063774-36070089:+PAADEERT_cells_CD4_memory_activated2.6094e-03-0.4428image
ENSG00000126070.17,AGO3PAADEAGT_cells_CD4_memory_activated1.7124e-03-0.4544image
chr1:36063774-36070089:+SKCMEERNeutrophils1.1636e-030.2850image
ENSG00000126070.17,AGO3SKCMEAGNeutrophils1.1637e-030.2850image
chr1:36047044-36049446:+STADEERT_cells_CD4_memory_activated1.5429e-030.4404image
chr1:36050878-36051636:+STADEERMast_cells_resting5.4072e-030.4802image
chr1:36063774-36070089:+THYMEERB_cells_naive3.9292e-020.3314image
ENSG00000126070.17,AGO3THYMEAGT_cells_regulatory_(Tregs)3.6756e-02-0.3313image
chr1:36063774-36070089:+UCECEERNeutrophils1.0158e-020.5359image
ENSG00000126070.17,AGO3UCSEAGMacrophages_M04.4104e-020.4330image


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6. Enriched editing regions and immune gene sets for AGO3


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot
chr1:36063774-36070089:+OVEER3.0545e-030.23954.4251e-020.16409.8828e-030.20943.1698e-020.1749image


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
ENSG00000126070.17,AGO3BLCAGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG4.7076e-020.2399image
chr1:36063774-36070089:+BLCAGSVA_HALLMARK_PEROXISOMEEER3.2569e-02-0.2655image
chr1:36063774-36070089:+BRCAGSVA_HALLMARK_UV_RESPONSE_DNEER1.5593e-02-0.1000image
chr1:36056797-36057972:+BRCAGSVA_HALLMARK_NOTCH_SIGNALINGEER2.8097e-020.4577image
ENSG00000126070.17,AGO3CESCGSVA_HALLMARK_MYOGENESISEAG3.2683e-020.2613image
ENSG00000126070.17,AGO3COADGSVA_HALLMARK_HEME_METABOLISMEAG1.5796e-03-0.4673image
chr1:36063774-36070089:+COADGSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALINGEER2.9256e-03-0.4480image
ENSG00000126070.17,AGO3ESCAGSVA_HALLMARK_ADIPOGENESISEAG2.5013e-020.1901image
chr1:36056797-36057972:+ESCAGSVA_HALLMARK_BILE_ACID_METABOLISMEER3.4042e-04-0.5210image
chr1:36063774-36070089:+ESCAGSVA_HALLMARK_E2F_TARGETSEER2.4202e-02-0.1976image
chr1:36047044-36049446:+ESCAGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER7.5754e-040.5812image
ENSG00000126070.17,AGO3GBMGSVA_HALLMARK_ADIPOGENESISEAG4.8512e-040.3258image
chr1:36063774-36070089:+GBMGSVA_HALLMARK_ADIPOGENESISEER4.9051e-040.3255image
chr1:36063774-36070089:+HNSCGSVA_HALLMARK_BILE_ACID_METABOLISMEER4.0711e-02-0.2082image
ENSG00000126070.17,AGO3KIRCGSVA_HALLMARK_MITOTIC_SPINDLEEAG2.0801e-02-0.1655image
chr1:36063774-36070089:+KIRCGSVA_HALLMARK_MITOTIC_SPINDLEEER1.7644e-02-0.1716image
ENSG00000126070.17,AGO3KIRPGSVA_HALLMARK_MYC_TARGETS_V1EAG4.1641e-020.2215image
chr1:36063774-36070089:+KIRPGSVA_HALLMARK_KRAS_SIGNALING_DNEER4.6753e-02-0.2176image
ENSG00000126070.17,AGO3LAMLGSVA_HALLMARK_APICAL_JUNCTIONEAG1.5840e-020.2036image
chr1:36063774-36070089:+LAMLGSVA_HALLMARK_APICAL_JUNCTIONEER4.8046e-020.1737image
chr1:36063774-36070089:+LGGGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER7.9147e-05-0.1921image
ENSG00000126070.17,AGO3LGGGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG8.6808e-05-0.1910image
chr1:36063774-36070089:+LUSCGSVA_HALLMARK_ADIPOGENESISEER8.0324e-030.2281image
ENSG00000126070.17,AGO3LUSCGSVA_HALLMARK_BILE_ACID_METABOLISMEAG3.8396e-030.2455image
chr1:36063774-36070089:+OVGSVA_HALLMARK_HEME_METABOLISMEER4.9896e-030.2274image
chr1:36047044-36049446:+OVGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER2.2501e-030.5534image
ENSG00000126070.17,AGO3OVGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG1.8810e-040.2851image
ENSG00000126070.17,AGO3PAADGSVA_HALLMARK_APICAL_JUNCTIONEAG1.1088e-020.3752image
chr1:36063774-36070089:+PAADGSVA_HALLMARK_APICAL_JUNCTIONEER1.4776e-020.3652image
chr1:36063774-36070089:+SARCGSVA_HALLMARK_ANDROGEN_RESPONSEEER1.5835e-020.2432image
ENSG00000126070.17,AGO3SARCGSVA_HALLMARK_ANDROGEN_RESPONSEEAG2.9163e-020.2172image
ENSG00000126070.17,AGO3SKCMGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEAG7.2714e-030.2371image
chr1:36063774-36070089:+SKCMGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEER7.2913e-030.2370image
chr1:36047044-36049446:+STADGSVA_HALLMARK_P53_PATHWAYEER2.3685e-030.4245image
chr1:36063774-36070089:+STADGSVA_HALLMARK_XENOBIOTIC_METABOLISMEER3.7165e-040.2384image
ENSG00000126070.17,AGO3STADGSVA_HALLMARK_XENOBIOTIC_METABOLISMEAG5.5595e-070.3139image
chr1:36050878-36051636:+STADGSVA_HALLMARK_APICAL_SURFACEEER1.4239e-020.4292image
ENSG00000126070.17,AGO3THCAGSVA_HALLMARK_MYC_TARGETS_V2EAG3.7584e-030.1626image
chr1:36063774-36070089:+THCAGSVA_HALLMARK_MYC_TARGETS_V2EER2.4782e-030.1707image
ENSG00000126070.17,AGO3THYMGSVA_HALLMARK_SPERMATOGENESISEAG3.7195e-02-0.3306image
chr1:36063774-36070089:+THYMGSVA_HALLMARK_ANDROGEN_RESPONSEEER5.3749e-04-0.5289image
ENSG00000126070.17,AGO3UCECGSVA_HALLMARK_PROTEIN_SECRETIONEAG3.4784e-02-0.4237image
chr1:36063774-36070089:+UCSGSVA_HALLMARK_DNA_REPAIREER2.2987e-020.5055image
ENSG00000126070.17,AGO3UCSGSVA_HALLMARK_SPERMATOGENESISEAG1.9982e-020.4922image


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7. Enriched editing regions and drugs for AGO3


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
ENSG00000126070.17,AGO3BLCAMG.132EAG1.1200e-020.3036image
chr1:36063774-36070089:+BLCAMG.132EER2.6984e-030.3662image
ENSG00000126070.17,AGO3BRCAFH535EAG3.8092e-020.0853image
chr1:36056797-36057972:+BRCABosutinibEER3.2502e-020.4470image
chr1:36063774-36070089:+BRCAFH535EER2.6457e-020.0918image
ENSG00000126070.17,AGO3CESCFH535EAG4.5495e-02-0.2452image
chr1:36063774-36070089:+CESCCytarabineEER2.2408e-020.2808image
chr1:36063774-36070089:+COADLFM.A13EER1.0657e-02-0.3901image
ENSG00000126070.17,AGO3COADGefitinibEAG6.5951e-03-0.4081image
chr1:36047044-36049446:+ESCABexaroteneEER1.8819e-02-0.4263image
ENSG00000126070.17,AGO3ESCABIRB.0796EAG1.4654e-020.2066image
chr1:36056797-36057972:+ESCAGemcitabineEER5.1408e-04-0.5075image
chr1:36063774-36070089:+ESCACI.1040EER1.9925e-02-0.2040image
chr1:36063774-36070089:+GBMBIRB.0796EER2.7121e-030.2820image
ENSG00000126070.17,AGO3GBMBIRB.0796EAG2.6795e-030.2823image
chr1:36063774-36070089:+HNSCCyclopamineEER3.0070e-020.2204image
ENSG00000126070.17,AGO3HNSCGSK.650394EAG3.6895e-02-0.2069image
ENSG00000126070.17,AGO3KIRCABT.263EAG3.6437e-020.1499image
chr1:36063774-36070089:+KIRCABT.263EER4.7271e-020.1437image
ENSG00000126070.17,AGO3KIRPJNJ.26854165EAG4.1447e-020.2217image
chr1:36063774-36070089:+LAMLJNK.Inhibitor.VIIIEER1.7670e-02-0.2078image
ENSG00000126070.17,AGO3LAMLAZD6244EAG2.8442e-06-0.3839image
ENSG00000126070.17,AGO3LGGABT.888EAG4.7100e-050.1979image
chr1:36063774-36070089:+LGGLapatinibEER8.7573e-05-0.1909image
ENSG00000126070.17,AGO3LUADAZD6244EAG1.1676e-02-0.1996image
chr1:36063774-36070089:+LUADAZD6244EER1.9655e-02-0.1878image
ENSG00000126070.17,AGO3LUSCCGP.082996EAG3.7806e-03-0.2459image
chr1:36063774-36070089:+LUSCCGP.082996EER2.7885e-03-0.2564image
chr1:36063774-36070089:+MESOFH535EER2.8839e-03-0.5608image
ENSG00000126070.17,AGO3MESOFH535EAG1.3648e-03-0.5846image
ENSG00000126070.17,AGO3OVCMKEAG2.5881e-03-0.2317image
chr1:36047044-36049446:+OVCisplatinEER3.8821e-03-0.5279image
chr1:36063774-36070089:+OVJW.7.52.1EER1.5016e-02-0.1976image
chr1:36063774-36070089:+PAADATRAEER1.5025e-030.4744image
ENSG00000126070.17,AGO3PAADATRAEAG4.6334e-030.4237image
ENSG00000126070.17,AGO3PCPGBMS.708163EAG3.5702e-020.2497image
chr1:36063774-36070089:+PCPGBMS.708163EER3.3651e-020.2525image
chr1:36063774-36070089:+PRADEHT.1864EER4.9415e-02-0.1951image
ENSG00000126070.17,AGO3PRADEHT.1864EAG5.1450e-03-0.2650image
chr1:36063774-36070089:+SARCGW843682XEER1.6624e-030.3136image
ENSG00000126070.17,AGO3SARCGW843682XEAG1.0894e-030.3204image
ENSG00000126070.17,AGO3SKCMCCT007093EAG2.1527e-030.2699image
chr1:36063774-36070089:+SKCMCCT007093EER2.1601e-030.2698image
chr1:36063774-36070089:+STADEHT.1864EER1.3357e-020.1670image
chr1:36050878-36051636:+STADJNK.9LEER3.4252e-03-0.5019image
chr1:36047044-36049446:+STADBMS.708163EER1.6740e-02-0.3403image
ENSG00000126070.17,AGO3STADEHT.1864EAG1.8788e-030.1981image
chr1:36063774-36070089:+THCACCT007093EER3.5797e-030.1645image
ENSG00000126070.17,AGO3THCAAG.014699EAG7.0124e-030.1514image
ENSG00000126070.17,AGO3THYMCamptothecinEAG2.9124e-030.4587image
chr1:36063774-36070089:+THYMCamptothecinEER1.2990e-020.3943image
chr1:36063774-36070089:+UCECBI.2536EER1.0006e-020.5368image
ENSG00000126070.17,AGO3UCECAZD6244EAG9.1934e-03-0.5100image
chr1:36063774-36070089:+UCSCamptothecinEER1.2082e-02-0.5495image
ENSG00000126070.17,AGO3UCSFTI.277EAG1.7736e-02-0.5003image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType