CAeditome Logo

Home

Download

Statistics

Landscape

Help

Contact
Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: GABPB2 (ImmuneEditome ID:126626)

1. Gene summary of enriched editing regions for GABPB2

check button Gene summary
Gene informationGene symbol

GABPB2

Gene ID

126626

GeneSynonymsGABPB-2
GeneCytomap

1q21.3

GeneTypeprotein-coding
GeneDescriptionGA-binding protein subunit beta-2|GA binding protein transcription factor beta subunit 2|GABP subunit beta-2
GeneModificationdate20230329
UniprotIDQ8TAK5;Q5SZG2;A0A024R5R5;A0A024R5X6
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr1:151071685-151076626:+ENST00000462520.4ENSG00000143458.10GABPB2ncRNA_exonicAluY,AluSc8,AluYk4,AluSq2,AluSg,AluSz,MIRc,MER41-int,MER41A,AluJb,AluJr,(T)n,L1ME4b,AluSxchr1:151071685-151076626:+.alignment
chr1:151077742-151084782:+ENST00000462520.4ENSG00000143458.10GABPB2ncRNA_intronicAluJo,AluSx,AluSg7,AluJr,(AAT)n,(TA)n,AluSz,AluSq2,AluSg,AluY,AluSx1,Charlie1a,AluSpchr1:151077742-151084782:+.alignment
chr1:151077742-151084782:+ENST00000486076.4ENSG00000143458.10GABPB2ncRNA_intronicAluJo,AluSx,AluSg7,AluJr,(AAT)n,(TA)n,AluSz,AluSq2,AluSg,AluY,AluSx1,Charlie1a,AluSpchr1:151077742-151084782:+.alignment
chr1:151077742-151084782:+ENST00000489549.4ENSG00000143458.10GABPB2ncRNA_intronicAluJo,AluSx,AluSg7,AluJr,(AAT)n,(TA)n,AluSz,AluSq2,AluSg,AluY,AluSx1,Charlie1a,AluSpchr1:151077742-151084782:+.alignment
chr1:151085533-151087628:+ENST00000462520.4ENSG00000143458.10GABPB2ncRNA_intronicAluSx,Alu,AluJb,AluY,AluSx1,Charlie1achr1:151085533-151087628:+.alignment
chr1:151085533-151087628:+ENST00000486076.4ENSG00000143458.10GABPB2ncRNA_intronicAluSx,Alu,AluJb,AluY,AluSx1,Charlie1achr1:151085533-151087628:+.alignment
chr1:151085533-151087628:+ENST00000489549.4ENSG00000143458.10GABPB2ncRNA_intronicAluSx,Alu,AluJb,AluY,AluSx1,Charlie1achr1:151085533-151087628:+.alignment
chr1:151101378-151101515:+ENST00000467551.1ENSG00000143458.10GABPB2ncRNA_intronicAluSqchr1:151101378-151101515:+.alignment
chr1:151101378-151101515:+ENST00000489549.4ENSG00000143458.10GABPB2ncRNA_intronicAluSqchr1:151101378-151101515:+.alignment
chr1:151107708-151108322:+ENST00000467551.1ENSG00000143458.10GABPB2ncRNA_intronicAluSz,L1ME4b,AluJbchr1:151107708-151108322:+.alignment
chr1:151118785-151121747:+ENST00000368918.6ENSG00000143458.10GABPB2UTR3AluSc8,AluSp,AluJr,AluSc,AluSg4chr1:151118785-151121747:+.alignment
chr1:151123151-151124470:+ENST00000368918.6ENSG00000143458.10GABPB2UTR3(T)n,AluSz6,AluSz,AluSx4,(A)n,A-rich,AluY,(AAAAT)nchr1:151123151-151124470:+.alignment


Top

2. Tumor-specific enriched editing regions for GABPB2


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chr1:151123151-151124470:+BRCAEER7.3325e-03image
ENSG00000143458.10,GABPB2BRCAEAG3.8271e-03image
chr1:151118785-151121747:+PRADEER1.0213e-02image
chr1:151118785-151121747:+THCAEER5.1799e-04image
chr1:151123151-151124470:+THCAEER2.2379e-09image
ENSG00000143458.10,GABPB2THCAEAG5.3568e-13image


Top

check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot
chr1:151123151-151124470:+THCAPathEER8.6290e-033.1626e-020.1019image


Top

check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
chr1:151077742-151084782:+ESCAEER2.0598e-023.2591e-021.0022e-02image
chr1:151123151-151124470:+LUADEER8.6901e-031.6483e-021.2095e+01image
chr1:151071685-151076626:+OVEER4.7693e-022.4386e-026.4114e+00image
chr1:151077742-151084782:+STADEER4.8923e-029.5936e-031.1607e-02image

Top

3. Enriched editing regions and immune related genes for GABPB2


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr1:151071685-151076626:+ESCAEERENSG00000269688,AC008982.2-0.48951.6927e-051.5234e-07-0.4319imageNDHX9;ELAVL1;FBL;HNRNPA2B1;HNRNPC;IGF2BP2;NOP56;NOP58;U2AF2;ZNF184NAB_cells_naiveGSVA_HALLMARK_GLYCOLYSIS
chr1:151071685-151076626:+ESCAEERENSG00000271870,RP11-97C16.1-0.47783.7793e-055.2945e-07-0.4144imageNEIF4A3;ELAVL1;NOP56NAT_cells_CD4_memory_restingGSVA_HALLMARK_P53_PATHWAY
chr1:151071685-151076626:+ESCAEERENSG00000065970,FOXJ20.44292.2203e-041.2333e-080.4644imageNADAR;EIF4A3;ELAVL1;FBL;HNRNPA2B1;HNRNPC;IGF2BP1;IGF2BP2;IGF2BP3;NOP56;NOP58;TROVE2;U2AF2;ZNF184NAMacrophages_M1GSVA_HALLMARK_HEDGEHOG_SIGNALING
chr1:151071685-151076626:+ESCAEERENSG00000070367,EXOC50.39301.4304e-033.2201e-080.4524imageNADAR;DHX9;EIF4A3;ELAVL1;FBL;HNRNPA2B1;HNRNPC;IGF2BP1;IGF2BP2;IGF2BP3;NOP56;NOP58;TROVE2;U2AF2;ZNF184EXOC5T_cells_regulatory_(Tregs)GSVA_HALLMARK_HEDGEHOG_SIGNALING
chr1:151071685-151076626:+ESCAEERENSG00000197102,DYNC1H10.40141.4753e-032.4607e-070.4253imageNADAR;DHX9;EIF4A3;ELAVL1;FBL;HNRNPA2B1;HNRNPC;IGF2BP1;IGF2BP2;IGF2BP3;NOP56;NOP58;TROVE2;U2AF2;ZNF184NAT_cells_regulatory_(Tregs)GSVA_HALLMARK_HEDGEHOG_SIGNALING
chr1:151071685-151076626:+ESCAEERENSG00000136875,PRPF40.37372.2047e-033.8233e-080.4502imageNADAR;DHX9;EIF4A3;ELAVL1;FBL;HNRNPA2B1;HNRNPC;IGF2BP1;IGF2BP2;IGF2BP3;NOP56;NOP58;TROVE2;U2AF2;ZNF184NAT_cells_follicular_helperGSVA_HALLMARK_E2F_TARGETS
chr1:151071685-151076626:+ESCAEERENSG00000082805,ERC10.33889.8464e-033.1586e-070.4218imageNADAR;DHX9;EIF4A3;ELAVL1;FBL;HNRNPA2B1;HNRNPC;IGF2BP1;IGF2BP2;IGF2BP3;NOP56;NOP58;TROVE2;U2AF2;ZNF184ERC1Dendritic_cells_activatedGSVA_HALLMARK_APICAL_SURFACE
chr1:151071685-151076626:+ESCAEERENSG00000067182,TNFRSF1A0.34521.0040e-021.6041e-070.4312imageNADAR;DHX9;EIF4A3;ELAVL1;FBL;HNRNPA2B1;HNRNPC;IGF2BP1;IGF2BP2;IGF2BP3;NOP56;NOP58;TROVE2;U2AF2;ZNF184TNFRSF1ADendritic_cells_activatedGSVA_HALLMARK_APICAL_SURFACE
chr1:151071685-151076626:+ESCAEERENSG00000185963,BICD20.31981.1098e-022.3333e-070.4260imageNADAR;DHX9;EIF4A3;ELAVL1;FBL;HNRNPA2B1;HNRNPC;IGF2BP1;IGF2BP2;IGF2BP3;NOP56;NOP58;TROVE2;U2AF2;ZNF184BICD2T_cells_regulatory_(Tregs)GSVA_HALLMARK_HYPOXIA
chr1:151071685-151076626:+ESCAEERENSG00000127152,BCL11B0.31331.1760e-023.9471e-070.4186imageNADAR;DHX9;EIF4A3;ELAVL1;FBL;HNRNPC;IGF2BP1;IGF2BP2;NOP56;NOP58;TROVE2;U2AF2;ZNF184BCL11BNK_cells_restingGSVA_HALLMARK_HEDGEHOG_SIGNALING
chr1:151118785-151121747:+STADEERENSG00000105669,COPE0.34501.2058e-068.0713e-140.4213imageNCSTF2T;DDX3X;DGCR8;EIF4A3;EIF4G2;FAM120A;FBL;FMR1;FUS;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPU;IGF2BP1;IGF2BP2;IGF2BP3;LIN28B;METTL3;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RBFOX2;SF3A3;SF3B4;SLTM;SRSF1;SRSF7;SRSF9;TAF15;TIA1;U2AF1;U2AF2;ZNF184NAMast_cells_restingGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY
chr1:151118785-151121747:+STADEERENSG00000105701,FKBP80.22593.6408e-031.4628e-120.4012imageNCSTF2T;DDX3X;DGCR8;EIF4A3;EIF4G2;FAM120A;FBL;FMR1;FUS;FXR2;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPU;IGF2BP1;IGF2BP2;IGF2BP3;LIN28B;METTL3;NOP58;NUMA1;PCBP2;PRPF8;PTBP1;RBFOX2;SF3A3;SF3B4;SLTM;SRSF1;SRSF7;SRSF9;TAF15;TIA1;U2AF1;U2AF2;ZNF184FKBP8T_cells_regulatory_(Tregs)GSVA_HALLMARK_KRAS_SIGNALING_DN
chr1:151123151-151124470:+CESCEERENSG00000128191,DGCR8-0.41401.6694e-086.7925e-12-0.4081imageNNDGCR8T_cells_regulatory_(Tregs)GSVA_HALLMARK_COAGULATION
chr1:151123151-151124470:+ESCAEERENSG00000019549,SNAI20.44161.7823e-055.1829e-080.4191imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_HYPOXIA
chr1:151123151-151124470:+ESCAEERENSG00000105329,TGFB10.43264.5790e-059.5139e-090.4394imageNNTGFB1T_cells_regulatory_(Tregs)GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:151123151-151124470:+ESCAEERENSG00000176170,SPHK10.43864.8756e-059.3220e-080.4117imageNNSPHK1T_cells_regulatory_(Tregs)GSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:151123151-151124470:+ESCAEERENSG00000143458,GABPB2-0.43209.5084e-053.6265e-08-0.4235imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_HYPOXIA
chr1:151123151-151124470:+ESCAEERENSG00000167693,NXN0.40831.4812e-046.9835e-080.4154imageNNNXNT_cells_regulatory_(Tregs)GSVA_HALLMARK_APICAL_JUNCTION
chr1:151123151-151124470:+ESCAEERENSG00000057019,DCBLD20.39054.3887e-044.1245e-080.4219imageNNDCBLD2B_cells_naiveGSVA_HALLMARK_BILE_ACID_METABOLISM
chr1:151123151-151124470:+ESCAEERENSG00000133818,RRAS20.37061.0093e-039.4074e-090.4396imageNNNAT_cells_regulatory_(Tregs)GSVA_HALLMARK_BILE_ACID_METABOLISM
chr1:151123151-151124470:+ESCAEERENSG00000070404,FSTL30.35622.7661e-031.6724e-070.4042imageNNFSTL3B_cells_naiveGSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:151123151-151124470:+ESCAEERENSG00000111145,ELK30.35263.2725e-035.1363e-080.4192imageNNNAMacrophages_M1GSVA_HALLMARK_TGF_BETA_SIGNALING

More results



Top

4. Enriched editing regions and immune related splicing for GABPB2


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr1:151123151-151124470:+
ESCAEERIRENSG00000076984.13chr197905807:7905855:7909754:7909896-0.29451.5968e-028.5316e-06-0.4002imageNNMAP2K7T_cells_regulatory_(Tregs)GSVA_HALLMARK_APICAL_SURFACE
chr1:151071685-151076626:+
ESCAEERIRENSG00000073331.13chr4112427569:112427665:112429148:112429253-0.38578.5536e-032.8025e-06-0.4020imageNADAR;DHX9;EIF4A3;ELAVL1;FBL;HNRNPA2B1;HNRNPC;IGF2BP1;IGF2BP2;IGF2BP3;NOP56;NOP58;TROVE2;U2AF2;ZNF184NAT_cells_CD4_memory_activatedGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING
chr1:151123151-151124470:+
ESCAEERESENSG00000138326.14chr1078037193:78037304:78037438:78037441:78040203:78040225-0.42316.3588e-047.5596e-08-0.4144imageNNNAB_cells_naiveGSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION
chr1:151071685-151076626:+
ESCAEERIRENSG00000185567.6chr14104937243:104946261:104946756:104948802-0.19062.8052e-028.6211e-09-0.5050imageNADAR;EIF4A3;ELAVL1;FBL;HNRNPA2B1;HNRNPC;IGF2BP1;IGF2BP2;NOP56;NOP58;U2AF2;ZNF184NANK_cells_activatedGSVA_HALLMARK_UV_RESPONSE_DN
chr1:151071685-151076626:+
ESCAEERIRENSG00000132950.14chr1319835476:19835689:19837655:19837821-0.39722.1534e-031.3528e-06-0.4229imageNADAR;DHX9;EIF4A3;ELAVL1;FBL;HNRNPA2B1;HNRNPC;IGF2BP1;IGF2BP2;IGF2BP3;NOP56;NOP58;TROVE2;U2AF2;ZNF184NADendritic_cells_restingGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING
chr1:151071685-151076626:+
ESCAEERIRENSG00000103266.6chr16681792:681880:682019:682076-0.47504.2053e-041.1264e-06-0.4033imageNDHX9;EIF4A3;ELAVL1;FBL;HNRNPA2B1;HNRNPC;IGF2BP1;IGF2BP2;IGF2BP3;NOP56;NOP58;TROVE2;U2AF2;ZNF184STUB1Macrophages_M0GSVA_HALLMARK_HEME_METABOLISM
chr1:151071685-151076626:+
ESCAEERMEXENSG00000122566.16chr726190124:26190460:26190992:26191011:26191055:26191128:26192494:26192577-0.48062.1755e-044.1843e-08-0.4490imageNADAR;DHX9;EIF4A3;ELAVL1;FBL;HNRNPA2B1;HNRNPC;IGF2BP1;IGF2BP2;IGF2BP3;NOP56;NOP58;TROVE2;U2AF2;ZNF184NAMacrophages_M0GSVA_HALLMARK_MTORC1_SIGNALING
chr1:151123151-151124470:+
ESCAEERIRENSG00000108439.5chr1747944615:47944715:47945860:47945912-0.36966.9266e-042.4047e-07-0.4507imageNNNAB_cells_naiveGSVA_HALLMARK_P53_PATHWAY
chr1:151071685-151076626:+
ESCAEERIRENSG00000116350.11chr129165889:29166912:29168502:29168638-0.38601.1164e-022.4394e-07-0.4283imageNADAR;DHX9;EIF4A3;ELAVL1;FBL;HNRNPA2B1;HNRNPC;IGF2BP1;IGF2BP2;IGF2BP3;NOP56;NOP58;TROVE2;U2AF2;ZNF184NAMacrophages_M2GSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALING
chr1:151071685-151076626:+
ESCAEERIRENSG00000188811.8chr1339039135:39039711:39044089:39044181-0.38185.5360e-033.6211e-06-0.4085imageNEIF4A3;ELAVL1;FBL;HNRNPA2B1;HNRNPC;IGF2BP1;IGF2BP2;IGF2BP3;NOP56;NOP58;TROVE2;U2AF2;ZNF184NAB_cells_naiveGSVA_HALLMARK_GLYCOLYSIS

More results



Top

5. Enriched editing regions and immune infiltration for GABPB2


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chr1:151123151-151124470:+ACCEERMacrophages_M21.2593e-020.3613image
ENSG00000143458.10,GABPB2ACCEAGMacrophages_M21.8670e-020.3419image
chr1:151118785-151121747:+BLCAEERNK_cells_resting1.9714e-050.4895image
chr1:151123151-151124470:+BLCAEERMacrophages_M05.2374e-030.1698image
ENSG00000143458.10,GABPB2BLCAEAGMacrophages_M05.4558e-030.1687image
chr1:151118785-151121747:+BRCAEERT_cells_CD4_memory_activated1.4200e-030.1301image
chr1:151123151-151124470:+BRCAEERB_cells_naive2.1780e-03-0.1000image
ENSG00000143458.10,GABPB2BRCAEAGNK_cells_activated1.3721e-030.1034image
chr1:151123151-151124470:+CESCEERDendritic_cells_resting4.3034e-03-0.1762image
ENSG00000143458.10,GABPB2CESCEAGT_cells_CD4_memory_activated4.9679e-030.1734image
chr1:151123151-151124470:+CHOLEERMacrophages_M12.4038e-020.4499image
ENSG00000143458.10,GABPB2CHOLEAGMacrophages_M19.3906e-030.4994image
chr1:151118785-151121747:+COADEERMast_cells_resting1.7204e-02-0.2924image
ENSG00000143458.10,GABPB2COADEAGEosinophils3.5046e-030.1956image
chr1:151123151-151124470:+DLBCEERNeutrophils1.9313e-030.5602image
ENSG00000143458.10,GABPB2DLBCEAGB_cells_naive6.2807e-03-0.4659image
chr1:151071685-151076626:+ESCAEERB_cells_naive1.1422e-03-0.2760image
chr1:151118785-151121747:+ESCAEERT_cells_CD4_memory_resting1.0921e-02-0.2123image
chr1:151123151-151124470:+ESCAEERB_cells_naive1.0706e-04-0.3052image
ENSG00000143458.10,GABPB2ESCAEAGT_cells_regulatory_(Tregs)6.5530e-05-0.3131image
ENSG00000143458.10,GABPB2GBMEAGT_cells_CD4_memory_activated1.0743e-020.2738image
chr1:151118785-151121747:+HNSCEERMacrophages_M04.8992e-030.2765image
chr1:151123151-151124470:+HNSCEERNK_cells_activated1.5456e-020.1555image
ENSG00000143458.10,GABPB2HNSCEAGNK_cells_activated8.3904e-030.1638image
chr1:151118785-151121747:+KIRCEERPlasma_cells1.7131e-030.2591image
chr1:151123151-151124470:+KIRCEERB_cells_memory2.1134e-02-0.1395image
ENSG00000143458.10,GABPB2KIRCEAGMacrophages_M01.8626e-020.1398image
chr1:151123151-151124470:+KIRPEERMonocytes2.2767e-020.1783image
ENSG00000143458.10,GABPB2KIRPEAGPlasma_cells1.6144e-020.1870image
chr1:151123151-151124470:+LAMLEERMacrophages_M21.9358e-02-0.3880image
ENSG00000143458.10,GABPB2LAMLEAGDendritic_cells_resting1.9527e-040.3913image
chr1:151123151-151124470:+LGGEERMast_cells_activated5.8517e-030.1415image
ENSG00000143458.10,GABPB2LGGEAGMast_cells_activated1.9471e-030.1576image
chr1:151123151-151124470:+LIHCEERPlasma_cells9.2414e-030.2275image
ENSG00000143458.10,GABPB2LIHCEAGMacrophages_M02.2200e-020.1975image
chr1:151118785-151121747:+LUADEERMast_cells_activated1.2304e-020.2507image
chr1:151123151-151124470:+LUADEERT_cells_CD4_memory_activated2.4768e-050.2474image
ENSG00000143458.10,GABPB2LUADEAGT_cells_CD4_memory_activated2.3298e-070.2932image
chr1:151071685-151076626:+LUSCEERT_cells_gamma_delta1.1287e-030.5925image
chr1:151118785-151121747:+LUSCEERT_cells_CD4_naive1.1806e-040.3338image
chr1:151123151-151124470:+LUSCEERT_cells_follicular_helper4.2433e-04-0.1938image
ENSG00000143458.10,GABPB2LUSCEAGT_cells_follicular_helper1.3331e-03-0.1751image
chr1:151123151-151124470:+MESOEEREosinophils3.3463e-020.2983image
ENSG00000143458.10,GABPB2MESOEAGEosinophils2.4357e-020.3150image
chr1:151071685-151076626:+OVEERB_cells_naive4.9932e-03-0.1818image
chr1:151077742-151084782:+OVEERNK_cells_resting2.9779e-020.2082image
chr1:151085533-151087628:+OVEEREosinophils1.0666e-02-0.5329image
chr1:151123151-151124470:+OVEERB_cells_memory1.4609e-040.2447image
ENSG00000143458.10,GABPB2OVEAGB_cells_memory8.7408e-050.2386image
chr1:151118785-151121747:+PAADEEREosinophils4.1935e-030.4144image
chr1:151123151-151124470:+PAADEERT_cells_CD4_memory_activated2.4300e-03-0.2570image
chr1:151118785-151121747:+PCPGEERNK_cells_resting2.1879e-020.4393image
chr1:151123151-151124470:+PCPGEEREosinophils9.0820e-040.3079image
ENSG00000143458.10,GABPB2PCPGEAGEosinophils7.8129e-040.3089image
chr1:151118785-151121747:+PRADEERT_cells_follicular_helper1.6882e-02-0.1852image
chr1:151123151-151124470:+PRADEERDendritic_cells_activated1.1346e-020.1252image
chr1:151123151-151124470:+READEERDendritic_cells_resting7.0394e-030.2955image
ENSG00000143458.10,GABPB2READEAGDendritic_cells_resting6.1492e-030.2984image
chr1:151118785-151121747:+SARCEERNeutrophils3.3699e-020.2205image
chr1:151123151-151124470:+SARCEERMacrophages_M21.2991e-020.1754image
ENSG00000143458.10,GABPB2SARCEAGMacrophages_M23.8736e-020.1448image
chr1:151118785-151121747:+SKCMEERPlasma_cells1.3808e-020.2952image
chr1:151123151-151124470:+SKCMEERB_cells_naive2.6843e-02-0.1450image
chr1:151071685-151076626:+STADEERNK_cells_resting4.0406e-030.1704image
chr1:151085533-151087628:+STADEERB_cells_memory1.3475e-030.4013image
chr1:151118785-151121747:+STADEEREosinophils1.0442e-02-0.1507image
ENSG00000143458.10,GABPB2STADEAGT_cells_CD4_memory_activated3.9417e-040.1940image
chr1:151118785-151121747:+THCAEERNeutrophils4.7937e-030.2613image
chr1:151123151-151124470:+THCAEERDendritic_cells_activated6.4677e-040.1607image
ENSG00000143458.10,GABPB2THCAEAGDendritic_cells_activated3.8814e-030.1351image
chr1:151118785-151121747:+THYMEERT_cells_CD84.8001e-020.2964image
chr1:151123151-151124470:+THYMEERMast_cells_resting4.3414e-050.3879image
ENSG00000143458.10,GABPB2THYMEAGT_cells_CD4_naive4.2678e-04-0.3361image
chr1:151123151-151124470:+UCECEERMonocytes3.2414e-020.2221image
ENSG00000143458.10,GABPB2UCECEAGT_cells_gamma_delta4.7127e-020.2042image
ENSG00000143458.10,GABPB2UVMEAGT_cells_regulatory_(Tregs)3.3083e-040.6711image


Top

6. Enriched editing regions and immune gene sets for GABPB2


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot
chr1:151123151-151124470:+BLCAEER8.4180e-03image1.2289e-070.3157image
ENSG00000143458.10,GABPB2BLCAEAG8.1047e-03image1.1709e-070.3156image


Top

check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot
ENSG00000143458.10,GABPB2BRCAEAG9.3119e-070.15802.4292e-030.09801.6333e-030.10181.7902e-040.1210image
ENSG00000143458.10,GABPB2ESCAEAG1.3261e-040.30033.1768e-020.17156.7899e-060.35054.4738e-060.3569image
chr1:151123151-151124470:+LUADEER9.3458e-040.19549.5733e-040.19506.8943e-030.16008.7293e-040.1965image
ENSG00000143458.10,GABPB2LUADEAG1.9396e-040.21361.6186e-030.18136.7222e-030.15621.1284e-040.2211image
chr1:151071685-151076626:+STADEER6.2268e-030.16221.6583e-020.14232.1376e-030.18181.2992e-090.3507image


Top

check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
ENSG00000143458.10,GABPB2ACCGSVA_HALLMARK_SPERMATOGENESISEAG2.5292e-020.3261image
chr1:151123151-151124470:+ACCGSVA_HALLMARK_SPERMATOGENESISEER2.7278e-020.3220image
ENSG00000143458.10,GABPB2BLCAGSVA_HALLMARK_HEDGEHOG_SIGNALINGEAG6.8834e-080.3210image
chr1:151123151-151124470:+BLCAGSVA_HALLMARK_HEDGEHOG_SIGNALINGEER3.2745e-080.3290image
ENSG00000143458.10,GABPB2BRCAGSVA_HALLMARK_UV_RESPONSE_UPEAG3.7286e-130.2322image
chr1:151118785-151121747:+BRCAGSVA_HALLMARK_UV_RESPONSE_UPEER2.2496e-060.1918image
chr1:151123151-151124470:+BRCAGSVA_HALLMARK_GLYCOLYSISEER3.6930e-080.1786image
chr1:151118785-151121747:+CESCGSVA_HALLMARK_XENOBIOTIC_METABOLISMEER1.6239e-040.3551image
chr1:151123151-151124470:+CESCGSVA_HALLMARK_COMPLEMENTEER8.2883e-050.2412image
ENSG00000143458.10,GABPB2CESCGSVA_HALLMARK_MITOTIC_SPINDLEEAG3.4412e-05-0.2534image
ENSG00000143458.10,GABPB2CHOLGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEAG5.5797e-030.5278image
chr1:151123151-151124470:+CHOLGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEER1.5621e-020.4782image
ENSG00000143458.10,GABPB2COADGSVA_HALLMARK_SPERMATOGENESISEAG1.8161e-02-0.1588image
chr1:151123151-151124470:+DLBCGSVA_HALLMARK_CHOLESTEROL_HOMEOSTASISEER1.0590e-020.4753image
ENSG00000143458.10,GABPB2DLBCGSVA_HALLMARK_XENOBIOTIC_METABOLISMEAG2.5402e-030.5081image
ENSG00000143458.10,GABPB2ESCAGSVA_HALLMARK_HYPOXIAEAG4.4738e-060.3569image
chr1:151118785-151121747:+ESCAGSVA_HALLMARK_HYPOXIAEER4.5520e-040.2894image
chr1:151077742-151084782:+ESCAGSVA_HALLMARK_MYOGENESISEER2.4997e-030.3609image
chr1:151123151-151124470:+ESCAGSVA_HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITIONEER8.6656e-060.3478image
chr1:151085533-151087628:+ESCAGSVA_HALLMARK_MYC_TARGETS_V1EER9.9126e-030.5373image
chr1:151071685-151076626:+ESCAGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER2.6348e-050.3520image
chr1:151123151-151124470:+GBMGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER9.7196e-03-0.2806image
ENSG00000143458.10,GABPB2GBMGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEAG6.7473e-030.2901image
ENSG00000143458.10,GABPB2HNSCGSVA_HALLMARK_SPERMATOGENESISEAG4.3326e-04-0.2175image
chr1:151118785-151121747:+HNSCGSVA_HALLMARK_HYPOXIAEER6.0655e-030.2700image
chr1:151123151-151124470:+HNSCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.5796e-050.2736image
chr1:151123151-151124470:+KICHGSVA_HALLMARK_NOTCH_SIGNALINGEER3.8433e-020.2750image
chr1:151123151-151124470:+KIRCGSVA_HALLMARK_GLYCOLYSISEER2.0929e-070.3079image
chr1:151118785-151121747:+KIRCGSVA_HALLMARK_MYC_TARGETS_V2EER2.7159e-020.1841image
ENSG00000143458.10,GABPB2KIRCGSVA_HALLMARK_GLYCOLYSISEAG1.8666e-060.2790image
chr1:151123151-151124470:+KIRPGSVA_HALLMARK_PANCREAS_BETA_CELLSEER7.2849e-070.3765image
chr1:151118785-151121747:+KIRPGSVA_HALLMARK_DNA_REPAIREER1.0073e-020.4023image
ENSG00000143458.10,GABPB2KIRPGSVA_HALLMARK_PANCREAS_BETA_CELLSEAG5.5557e-060.3453image
ENSG00000143458.10,GABPB2LAMLGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG4.8988e-050.4233image
chr1:151118785-151121747:+LGGGSVA_HALLMARK_SPERMATOGENESISEER3.9882e-02-0.1963image
ENSG00000143458.10,GABPB2LGGGSVA_HALLMARK_KRAS_SIGNALING_DNEAG3.9530e-080.2758image
chr1:151123151-151124470:+LGGGSVA_HALLMARK_KRAS_SIGNALING_DNEER3.5815e-070.2582image
ENSG00000143458.10,GABPB2LIHCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG2.3900e-020.1951image
chr1:151123151-151124470:+LUADGSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALINGEER1.9838e-050.2502image
ENSG00000143458.10,GABPB2LUADGSVA_HALLMARK_UV_RESPONSE_UPEAG7.4169e-060.2555image
chr1:151118785-151121747:+LUADGSVA_HALLMARK_MYC_TARGETS_V2EER1.7645e-020.2381image
chr1:151118785-151121747:+LUSCGSVA_HALLMARK_HYPOXIAEER1.0399e-020.2258image
ENSG00000143458.10,GABPB2LUSCGSVA_HALLMARK_TNFA_SIGNALING_VIA_NFKBEAG5.5480e-040.1882image
chr1:151123151-151124470:+LUSCGSVA_HALLMARK_HYPOXIAEER7.3196e-040.1858image
chr1:151071685-151076626:+LUSCGSVA_HALLMARK_ALLOGRAFT_REJECTIONEER3.5552e-020.4061image
chr1:151123151-151124470:+MESOGSVA_HALLMARK_UNFOLDED_PROTEIN_RESPONSEEER3.6943e-020.2930image
ENSG00000143458.10,GABPB2MESOGSVA_HALLMARK_UNFOLDED_PROTEIN_RESPONSEEAG3.4490e-020.2967image
chr1:151085533-151087628:+OVGSVA_HALLMARK_PI3K_AKT_MTOR_SIGNALINGEER1.6727e-020.5042image
chr1:151123151-151124470:+OVGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEER9.0006e-050.2521image
chr1:151071685-151076626:+OVGSVA_HALLMARK_APOPTOSISEER2.4434e-060.3006image
chr1:151077742-151084782:+OVGSVA_HALLMARK_MYC_TARGETS_V2EER4.7729e-020.1901image
ENSG00000143458.10,GABPB2OVGSVA_HALLMARK_UNFOLDED_PROTEIN_RESPONSEEAG2.6163e-050.2552image
chr1:151118785-151121747:+OVGSVA_HALLMARK_P53_PATHWAYEER1.3706e-020.1882image
ENSG00000143458.10,GABPB2PAADGSVA_HALLMARK_NOTCH_SIGNALINGEAG4.0007e-020.1738image
chr1:151118785-151121747:+PCPGGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER1.4312e-020.4659image
chr1:151123151-151124470:+PRADGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER4.7253e-03-0.1396image
ENSG00000143458.10,GABPB2PRADGSVA_HALLMARK_XENOBIOTIC_METABOLISMEAG3.2174e-060.2260image
chr1:151118785-151121747:+PRADGSVA_HALLMARK_ADIPOGENESISEER1.8884e-030.2395image
chr1:151123151-151124470:+READGSVA_HALLMARK_PROTEIN_SECRETIONEER5.9908e-040.3711image
ENSG00000143458.10,GABPB2READGSVA_HALLMARK_PROTEIN_SECRETIONEAG5.5015e-040.3712image
chr1:151118785-151121747:+SARCGSVA_HALLMARK_HYPOXIAEER3.4405e-030.3004image
ENSG00000143458.10,GABPB2SARCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG9.8899e-050.2692image
chr1:151123151-151124470:+SARCGSVA_HALLMARK_GLYCOLYSISEER1.0032e-020.1817image
chr1:151118785-151121747:+SKCMGSVA_HALLMARK_MYC_TARGETS_V1EER1.2234e-020.3001image
chr1:151123151-151124470:+SKCMGSVA_HALLMARK_COAGULATIONEER1.1504e-020.1653image
ENSG00000143458.10,GABPB2SKCMGSVA_HALLMARK_COAGULATIONEAG2.1164e-020.1500image
chr1:151123151-151124470:+STADGSVA_HALLMARK_COAGULATIONEER9.5548e-060.2513image
chr1:151077742-151084782:+STADGSVA_HALLMARK_P53_PATHWAYEER6.9085e-030.2265image
chr1:151118785-151121747:+STADGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER1.6881e-070.3023image
chr1:151071685-151076626:+STADGSVA_HALLMARK_APOPTOSISEER2.2307e-110.3840image
ENSG00000143458.10,GABPB2STADGSVA_HALLMARK_COMPLEMENTEAG4.0838e-070.2745image
ENSG00000143458.10,GABPB2TGCTGSVA_HALLMARK_INFLAMMATORY_RESPONSEEAG6.8112e-030.3184image
chr1:151118785-151121747:+THCAGSVA_HALLMARK_P53_PATHWAYEER2.9006e-020.2037image
ENSG00000143458.10,GABPB2THCAGSVA_HALLMARK_COAGULATIONEAG8.6244e-080.2477image
chr1:151123151-151124470:+THCAGSVA_HALLMARK_ESTROGEN_RESPONSE_LATEEER2.5007e-090.2772image
chr1:151123151-151124470:+THYMGSVA_HALLMARK_MITOTIC_SPINDLEEER3.0047e-11-0.5917image
ENSG00000143458.10,GABPB2THYMGSVA_HALLMARK_MITOTIC_SPINDLEEAG6.5063e-12-0.6050image
chr1:151118785-151121747:+THYMGSVA_HALLMARK_COMPLEMENTEER2.3476e-020.3373image
chr1:151123151-151124470:+UCECGSVA_HALLMARK_UV_RESPONSE_UPEER2.3203e-020.2353image
ENSG00000143458.10,GABPB2UCECGSVA_HALLMARK_UV_RESPONSE_UPEAG3.8267e-020.2130image
ENSG00000143458.10,GABPB2UCSGSVA_HALLMARK_DNA_REPAIREAG6.5761e-030.4705image
chr1:151123151-151124470:+UCSGSVA_HALLMARK_DNA_REPAIREER6.5132e-030.4710image
ENSG00000143458.10,GABPB2UVMGSVA_HALLMARK_KRAS_SIGNALING_DNEAG5.6389e-030.5473image


Top

7. Enriched editing regions and drugs for GABPB2


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
chr1:151123151-151124470:+ACCATRAEER4.4743e-02-0.2942image
chr1:151118785-151121747:+BLCAAMG.706EER3.9153e-03-0.3430image
chr1:151123151-151124470:+BLCABX.795EER4.3669e-08-0.3262image
ENSG00000143458.10,GABPB2BLCABX.795EAG6.6481e-08-0.3214image
chr1:151123151-151124470:+BRCAAS601245EER4.5183e-030.0927image
ENSG00000143458.10,GABPB2BRCACCT007093EAG2.1626e-070.1668image
chr1:151118785-151121747:+BRCABMS.536924EER3.2382e-05-0.1692image
ENSG00000143458.10,GABPB2CESCCI.1040EAG4.4107e-07-0.3065image
chr1:151118785-151121747:+CESCA.770041EER9.6578e-05-0.3663image
chr1:151123151-151124470:+CESCCI.1040EER1.0278e-06-0.2970image
ENSG00000143458.10,GABPB2CHOLAS601245EAG2.6597e-020.4344image
chr1:151123151-151124470:+COADCI.1040EER4.7572e-02-0.1362image
ENSG00000143458.10,GABPB2COADCI.1040EAG3.7967e-02-0.1397image
chr1:151123151-151124470:+DLBCAxitinibEER8.1307e-030.4900image
ENSG00000143458.10,GABPB2DLBCDasatinibEAG4.4531e-04-0.5843image
chr1:151085533-151087628:+ESCAMG.132EER1.6865e-02-0.5036image
chr1:151071685-151076626:+ESCAImatinibEER1.1115e-03-0.2767image
chr1:151077742-151084782:+ESCAAZD8055EER3.1162e-03-0.3534image
chr1:151118785-151121747:+ESCACisplatinEER3.8548e-04-0.2929image
chr1:151123151-151124470:+ESCAFTI.277EER2.1754e-05-0.3329image
ENSG00000143458.10,GABPB2ESCACMKEAG6.8619e-04-0.2681image
chr1:151123151-151124470:+GBMBAY.61.3606EER1.9849e-040.3952image
ENSG00000143458.10,GABPB2GBMBI.2536EAG7.7589e-070.5035image
ENSG00000143458.10,GABPB2HNSCBIBW2992EAG1.3380e-07-0.3211image
chr1:151118785-151121747:+HNSCEHT.1864EER7.5988e-040.3282image
chr1:151123151-151124470:+HNSCAZD.0530EER6.7639e-06-0.2848image
ENSG00000143458.10,GABPB2KICHATRAEAG4.8264e-020.2628image
chr1:151118785-151121747:+KIRCGW.441756EER3.0341e-02-0.1806image
chr1:151123151-151124470:+KIRCIPA.3EER1.5736e-030.1908image
ENSG00000143458.10,GABPB2KIRCIPA.3EAG1.8872e-030.1843image
chr1:151123151-151124470:+KIRPGDC0941EER3.4438e-04-0.2770image
chr1:151118785-151121747:+KIRPEpothilone.BEER6.7243e-03-0.4217image
ENSG00000143458.10,GABPB2KIRPAZD7762EAG2.7103e-11-0.4888image
chr1:151123151-151124470:+LAMLCyclopamineEER4.5522e-02-0.3354image
ENSG00000143458.10,GABPB2LAMLCI.1040EAG7.6100e-03-0.2859image
ENSG00000143458.10,GABPB2LGGFH535EAG4.1838e-050.2075image
chr1:151123151-151124470:+LGGFH535EER1.2778e-050.2224image
chr1:151118785-151121747:+LGGCI.1040EER9.9063e-03-0.2461image
chr1:151123151-151124470:+LIHCMethotrexateEER3.2189e-020.1925image
ENSG00000143458.10,GABPB2LIHCCI.1040EAG3.7922e-02-0.1795image
ENSG00000143458.10,GABPB2LUADGSK269962AEAG4.4212e-05-0.2335image
chr1:151123151-151124470:+LUADABT.888EER1.6390e-030.1860image
chr1:151118785-151121747:+LUADDoxorubicinEER3.7963e-02-0.2089image
chr1:151123151-151124470:+LUSCGSK.650394EER9.9389e-030.1424image
ENSG00000143458.10,GABPB2LUSCAZ628EAG4.9997e-04-0.1897image
chr1:151071685-151076626:+LUSCEHT.1864EER1.1081e-02-0.4810image
chr1:151118785-151121747:+LUSCBexaroteneEER1.4994e-02-0.2146image
ENSG00000143458.10,GABPB2MESOEHT.1864EAG6.1702e-040.4633image
chr1:151123151-151124470:+MESOEHT.1864EER1.0174e-030.4467image
chr1:151071685-151076626:+OVGNF.2EER7.7014e-03-0.1727image
ENSG00000143458.10,GABPB2OVCCT007093EAG3.8974e-040.2163image
chr1:151077742-151084782:+OVJNJ.26854165EER2.7490e-020.2112image
chr1:151123151-151124470:+OVJW.7.52.1EER2.4631e-05-0.2709image
chr1:151085533-151087628:+OVCCT018159EER3.0980e-03-0.6010image
chr1:151118785-151121747:+OVAZD6244EER8.2312e-03-0.2015image
chr1:151123151-151124470:+PAADABT.888EER4.3066e-030.2442image
chr1:151118785-151121747:+PAADA.770041EER1.4024e-02-0.3678image
ENSG00000143458.10,GABPB2PAADBosutinibEAG3.3186e-020.1814image
ENSG00000143458.10,GABPB2PCPGJNK.9LEAG3.0534e-020.2018image
chr1:151118785-151121747:+PCPGBIRB.0796EER1.9796e-030.5684image
chr1:151123151-151124470:+PCPGJNK.9LEER2.3228e-020.2134image
chr1:151123151-151124470:+PRADGDC.0449EER1.6043e-02-0.1191image
chr1:151118785-151121747:+PRADEpothilone.BEER2.5935e-030.2323image
ENSG00000143458.10,GABPB2PRADBAY.61.3606EAG1.0902e-040.1886image
chr1:151123151-151124470:+READBMS.708163EER2.2139e-04-0.3970image
ENSG00000143458.10,GABPB2READBMS.708163EAG3.9951e-04-0.3797image
ENSG00000143458.10,GABPB2SARCAZD.2281EAG2.7509e-16-0.5318image
chr1:151118785-151121747:+SARCBAY.61.3606EER3.9851e-050.4125image
chr1:151123151-151124470:+SARCA.770041EER5.3481e-06-0.3155image
chr1:151118785-151121747:+SKCMBI.D1870EER4.0999e-03-0.3413image
ENSG00000143458.10,GABPB2SKCMCMKEAG6.0427e-03-0.1782image
chr1:151123151-151124470:+SKCMCMKEER5.4967e-03-0.1814image
ENSG00000143458.10,GABPB2STADAZ628EAG9.5049e-05-0.2132image
chr1:151071685-151076626:+STADEmbelinEER6.0917e-06-0.2652image
chr1:151077742-151084782:+STADCI.1040EER1.7732e-03-0.2610image
chr1:151118785-151121747:+STADBortezomibEER2.0593e-05-0.2481image
chr1:151123151-151124470:+STADAZ628EER1.3006e-08-0.3194image
chr1:151123151-151124470:+TGCTLFM.A13EER3.4810e-020.2545image
ENSG00000143458.10,GABPB2TGCTBI.2536EAG7.8924e-050.4510image
chr1:151118785-151121747:+THCAAZD8055EER1.4981e-020.2264image
ENSG00000143458.10,GABPB2THCACCT007093EAG1.1269e-090.2805image
chr1:151123151-151124470:+THCACI.1040EER1.3544e-09-0.2816image
chr1:151118785-151121747:+THYMFTI.277EER3.3808e-020.3171image
chr1:151123151-151124470:+THYMABT.263EER7.8284e-070.4602image
ENSG00000143458.10,GABPB2THYMEmbelinEAG9.3036e-090.5224image
chr1:151123151-151124470:+UCECAZD.2281EER1.0347e-030.3349image
ENSG00000143458.10,GABPB2UCECEHT.1864EAG8.6883e-030.2678image
ENSG00000143458.10,GABPB2UCSGW843682XEAG1.0049e-02-0.4484image
chr1:151123151-151124470:+UCSGW843682XEER1.0381e-02-0.4467image
ENSG00000143458.10,GABPB2UVMGSK269962AEAG2.3370e-03-0.5914image


Top

check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType