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Center for Computational Systems Medicine
Soverview

1. Gene summary of enriched editing regions

Soverview

2. Tumor-specific enriched editing regions

Comparison of enriched editing regions between tumor and normal.

Correlation of enriched editing regions with tumor stages.

Associations of enriched editing regions with cancer survival.

Soverview

3. Enriched editing regions and immune related genes

Soverview

4. Enriched editing regions and immune related splicing

Soverview

5. Enriched editing regions and immune infiltration

Soverview

6. Enriched editing regions and immune gene sets

Correlation of enriched editing regions with epithelial-mesenchymal transition.

Correlations of enriched editing regions with hypoxic.

Associations of enriched editing regions with hallmark gene sets from MSigDB.

Soverview

7. Enriched editing regions and drugs

Correlations between enriched editing regions and drug sensitivity.

Enriched editing regions targeted by drugs from DrugBank database.

Editing gene: FGD5-AS1 (ImmuneEditome ID:100505641)

1. Gene summary of enriched editing regions for FGD5-AS1

check button Gene summary
Gene informationGene symbol

FGD5-AS1

Gene ID

100505641

GeneSynonyms-
GeneCytomap

3p25.1

GeneTypencRNA
GeneDescriptionFGD5 antisense RNA 1 (non-protein coding)
GeneModificationdate20230329
UniprotID.
PubMed ID

check buttonUCSC image.
all structure

check buttonLocations of each EERs.
EERENSTENSGGeneNameRegionRepeatdsRNA structure
chr3:14944542-14944994:-ENST00000417835.1ENSG00000225733.4FGD5-AS1ncRNA_exonicAluSz6,AluSq2chr3:14944542-14944994:-.alignment
chr3:14944542-14944994:-ENST00000424349.1ENSG00000225733.4FGD5-AS1ncRNA_exonicAluSz6,AluSq2chr3:14944542-14944994:-.alignment
chr3:14944542-14944994:-ENST00000426200.1ENSG00000225733.4FGD5-AS1ncRNA_exonicAluSz6,AluSq2chr3:14944542-14944994:-.alignment


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2. Tumor-specific enriched editing regions for FGD5-AS1


all structure

check buttonComparison of enriched editing regions between tumor and normal.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypePBoxplot
chr3:14944542-14944994:-BRCAEER1.9758e-05image
ENSG00000225733.4,FGD5-AS1BRCAEAG1.9758e-05image
chr3:14944542-14944994:-HNSCEER2.6141e-14image
ENSG00000225733.4,FGD5-AS1HNSCEAG2.6141e-14image
ENSG00000225733.4,FGD5-AS1KICHEAG2.9213e-09image
chr3:14944542-14944994:-KIRCEER5.1511e-04image
ENSG00000225733.4,FGD5-AS1KIRCEAG5.0632e-04image
chr3:14944542-14944994:-KIRPEER1.2001e-04image
ENSG00000225733.4,FGD5-AS1KIRPEAG1.2001e-04image
chr3:14944542-14944994:-LIHCEER5.0061e-03image
ENSG00000225733.4,FGD5-AS1LIHCEAG5.0061e-03image
chr3:14944542-14944994:-LUSCEER4.0697e-06image
ENSG00000225733.4,FGD5-AS1LUSCEAG4.0697e-06image


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check buttonCorrelation of enriched editing regions with tumor stages.
* AnovaP<0.05, Pearson P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes, Path: Pathological stage, Cli: Clinical stage.
* Only shows the most significant correlation result of EERs/EAGs with either pathological stage or clinical stage according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeStageTypeAnovaPPRBoxplot


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check button Associations of enriched editing regions with cancer survival.
* Pkm<0.05 and Pcox<0.05.
* EER: enriched editing region, EAG: EER-associated genes.
ID_eventscancerTypeIDPkmPcox_continuousHR_continuousKMPlot
chr3:14944542-14944994:-LGGEER1.7295e-023.9847e-025.8001e+01image
ENSG00000225733.4,FGD5-AS1LGGEAG1.7295e-023.9847e-025.8001e+01image

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3. Enriched editing regions and immune related genes for FGD5-AS1


all structure

check button Enriched editing regions and immune related genes.
* First, the associations between enriched editing regions and genes were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the gene relationships with immune were tested by three analyses: whether the gene is an immune gene (InnateDB、Immport、Immunome、Immunogenetic Related Information Source (IRIS)), whether the gene is associated with immune infiltration and whether the gene is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of genes with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeGenebetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
chr3:14944542-14944994:-BLCAEERENSG00000115415,STAT10.47155.7928e-193.7601e-170.4104imageNFUS;HNRNPL;IGF2BP2STAT1T_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000168394,TAP10.45917.7012e-188.2468e-170.4062imageNFUS;HNRNPL;IGF2BP2TAP1T_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000156587,UBE2L60.45322.4857e-177.1612e-170.4070imageNFUS;HNRNPL;IGF2BP2NAT_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000204267,TAP20.45044.0017e-179.2071e-180.4176imageNFUS;IGF2BP2TAP2T_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000160710,ADAR0.44945.1881e-173.2399e-170.4111imageNFUS;HNRNPL;IGF2BP2ADARMacrophages_M1GSVA_HALLMARK_MITOTIC_SPINDLE
chr3:14944542-14944994:-BLCAEERENSG00000234745,HLA-B0.44786.5897e-171.7760e-160.4022imageNFUS;HNRNPL;IGF2BP2HLA-BT_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000123609,NMI0.43477.6306e-164.0375e-170.4100imageNFUS;HNRNPL;IGF2BP2NAT_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000123130,ACOT90.42602.5035e-159.0771e-170.4057imageNFUS;HNRNPL;IGF2BP2NAT_cells_CD4_memory_activatedGSVA_HALLMARK_COMPLEMENT
chr3:14944542-14944994:-BLCAEERENSG00000168461,RAB310.41291.1417e-141.1631e-160.4044imageNFUS;HNRNPL;IGF2BP2NAT_cells_CD4_memory_activatedGSVA_HALLMARK_INFLAMMATORY_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000135077,HAVCR20.40545.4708e-141.3991e-160.4034imageNFUS;HNRNPL;IGF2BP2HAVCR2T_cells_CD4_memory_activatedGSVA_HALLMARK_ALLOGRAFT_REJECTION
chr3:14944542-14944994:-BLCAEERENSG00000115415,STAT10.47155.7928e-193.7601e-170.4104imageNFUS;HNRNPL;IGF2BP2STAT1T_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000168394,TAP10.45917.7012e-188.2468e-170.4062imageNFUS;HNRNPL;IGF2BP2TAP1T_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000156587,UBE2L60.45322.4857e-177.1612e-170.4070imageNFUS;HNRNPL;IGF2BP2NAT_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000204267,TAP20.45044.0017e-179.2071e-180.4176imageNFUS;IGF2BP2TAP2T_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000160710,ADAR0.44945.1881e-173.2399e-170.4111imageNFUS;HNRNPL;IGF2BP2ADARMacrophages_M1GSVA_HALLMARK_MITOTIC_SPINDLE
chr3:14944542-14944994:-BLCAEERENSG00000234745,HLA-B0.44786.5897e-171.7760e-160.4022imageNFUS;HNRNPL;IGF2BP2HLA-BT_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000123609,NMI0.43477.6306e-164.0375e-170.4100imageNFUS;HNRNPL;IGF2BP2NAT_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000123130,ACOT90.42602.5035e-159.0771e-170.4057imageNFUS;HNRNPL;IGF2BP2NAT_cells_CD4_memory_activatedGSVA_HALLMARK_COMPLEMENT
chr3:14944542-14944994:-BLCAEERENSG00000168461,RAB310.41291.1417e-141.1631e-160.4044imageNFUS;HNRNPL;IGF2BP2NAT_cells_CD4_memory_activatedGSVA_HALLMARK_INFLAMMATORY_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000135077,HAVCR20.40545.4708e-141.3991e-160.4034imageNFUS;HNRNPL;IGF2BP2HAVCR2T_cells_CD4_memory_activatedGSVA_HALLMARK_ALLOGRAFT_REJECTION
chr3:14944542-14944994:-BLCAEERENSG00000115415,STAT10.47155.7928e-193.7601e-170.4104imageNFUS;HNRNPL;IGF2BP2STAT1T_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000168394,TAP10.45917.7012e-188.2468e-170.4062imageNFUS;HNRNPL;IGF2BP2TAP1T_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000156587,UBE2L60.45322.4857e-177.1612e-170.4070imageNFUS;HNRNPL;IGF2BP2NAT_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000204267,TAP20.45044.0017e-179.2071e-180.4176imageNFUS;IGF2BP2TAP2T_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000160710,ADAR0.44945.1881e-173.2399e-170.4111imageNFUS;HNRNPL;IGF2BP2ADARMacrophages_M1GSVA_HALLMARK_MITOTIC_SPINDLE
chr3:14944542-14944994:-BLCAEERENSG00000234745,HLA-B0.44786.5897e-171.7760e-160.4022imageNFUS;HNRNPL;IGF2BP2HLA-BT_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000123609,NMI0.43477.6306e-164.0375e-170.4100imageNFUS;HNRNPL;IGF2BP2NAT_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000123130,ACOT90.42602.5035e-159.0771e-170.4057imageNFUS;HNRNPL;IGF2BP2NAT_cells_CD4_memory_activatedGSVA_HALLMARK_COMPLEMENT
chr3:14944542-14944994:-BLCAEERENSG00000168461,RAB310.41291.1417e-141.1631e-160.4044imageNFUS;HNRNPL;IGF2BP2NAT_cells_CD4_memory_activatedGSVA_HALLMARK_INFLAMMATORY_RESPONSE
chr3:14944542-14944994:-BLCAEERENSG00000135077,HAVCR20.40545.4708e-141.3991e-160.4034imageNFUS;HNRNPL;IGF2BP2HAVCR2T_cells_CD4_memory_activatedGSVA_HALLMARK_ALLOGRAFT_REJECTION

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4. Enriched editing regions and immune related splicing for FGD5-AS1


all structure

check button Enriched editing regions and immune related splicing.
* First, the associations between enriched editing regions and splicing events were tested by QTL and Pearson method (QTL: FDR<0.05 and Pearson: P<0.05).
* Second, the splicing relationships with immune were tested by three analyses: whether the splicing event locates in an immune gene (InnateDB、Immport, Immunome and Immunogenetic Related Information Source (IRIS)), whether the splicing event is associated with immune infiltration and whether the splicing event is related to immune gene sets.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of splicing events with the fraction of different immune cells and the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeSplicingTypeSplicingGeneSplicingChrSplicingPositionbetaFDRPearsonPPearsonRCorrelationPlotRBPRBPtargetsImmuneGeneImmuneFractionHallMark
ENSG00000225733.4,FGD5-AS1
BLCAEAGIRENSG00000130175.5chr1911449265:11449882:11450428:11450716-0.44565.5031e-154.2690e-23-0.4748imageNADAR;AIFM1;ALYREF;AUH;BCCIP;BUD13;CAPRIN1;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;EIF4A3;EIF4G1;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHDRBS2;KHDRBS3;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;PUM2;QKI;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RBM47;RBM6;RNF219;SAFB2;SBDS;SF3A3;SF3B4;SLBP;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARBP2;TARDBP;TIA1;TIAL1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YTHDF2;YWHAG;ZNF184PRKCSHMacrophages_M1GSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
ENSG00000225733.4,FGD5-AS1
BLCAEAGIRENSG00000076928.13chr1941897314:41897326:41897945:41897982-0.30463.6552e-091.6962e-13-0.4042imageNADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RNF219;SAFB2;SBDS;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZFP36;ZNF184NAT_cells_CD4_memory_activatedGSVA_HALLMARK_ALLOGRAFT_REJECTION
chr3:14944542-14944994:-
BLCAEERIRENSG00000205744.5chr196467206:6468645:6468845:6468953-0.35291.9673e-102.3926e-16-0.4115imageNFUS;HNRNPL;IGF2BP2NADendritic_cells_activatedGSVA_HALLMARK_ALLOGRAFT_REJECTION
chr3:14944542-14944994:-
BLCAEERIRENSG00000111679.12chr126951261:6951520:6951608:6951731-0.32603.6340e-108.9939e-16-0.4262imageNFUS;IGF2BP2PTPN6Dendritic_cells_activatedGSVA_HALLMARK_COMPLEMENT
chr3:14944542-14944994:-
BLCAEERIRENSG00000130175.5chr1911449265:11449882:11450428:11450716-0.44563.9996e-154.2690e-23-0.4748imageNFUS;HNRNPL;IGF2BP2PRKCSHMacrophages_M1GSVA_HALLMARK_INTERFERON_ALPHA_RESPONSE
chr3:14944542-14944994:-
BLCAEERESENSG00000083457.7chr173720306:3720402:3723287:3723383:3723687:37237440.35891.0963e-091.7453e-160.4027imageNFUS;HNRNPL;IGF2BP2ITGAET_cells_CD4_memory_activatedGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSE
chr3:14944542-14944994:-
BLCAEERIRENSG00000076928.13chr1941897314:41897326:41897945:41897982-0.30462.5522e-091.6962e-13-0.4042imageNFUS;HNRNPL;IGF2BP2NAT_cells_CD4_memory_activatedGSVA_HALLMARK_ALLOGRAFT_REJECTION
ENSG00000225733.4,FGD5-AS1
BLCAEAGIRENSG00000076928.13chr1941897314:41898113:41898441:41898587-0.36643.1690e-111.6502e-15-0.4074imageNADAR;AIFM1;AUH;BCCIP;BUD13;CELF2;CNBP;CPSF6;CSTF2T;DDX3X;DDX42;DDX54;DGCR8;DHX9;DICER1;DKC1;EIF4A3;EIF4G2;ELAVL1;EWSR1;FAM120A;FBL;FKBP4;FMR1;FTO;FUS;FXR1;FXR2;GNL3;GTF2F1;HNRNPA1;HNRNPA2B1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;KHSRP;LARP4B;LARP7;LIN28;LIN28A;LIN28B;LSM11;MOV10;MSI2;NONO;NOP56;NOP58;NPM1;NUMA1;PCBP2;PRPF8;PTBP1;RANGAP1;RBFOX2;RBM10;RBM22;RBM27;RNF219;SAFB2;SBDS;SF3A3;SF3B4;SLTM;SMNDC1;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;TIA1;TNRC6A;TRA2A;TROVE2;U2AF1;U2AF2;UPF1;VIM;XRN2;YTHDC1;YTHDF1;YWHAG;ZFP36;ZNF184NAT_cells_CD4_memory_activatedGSVA_HALLMARK_ALLOGRAFT_REJECTION
ENSG00000225733.4,FGD5-AS1
BLCAEAGIRENSG00000205744.5chr196467206:6468645:6468845:6468953-0.35292.7898e-102.3926e-16-0.4115imageNADAR;BCCIP;CELF2;CSTF2T;DGCR8;DKC1;EIF4A3;EIF4G2;ELAVL1;FBL;FUS;FXR1;GTF2F1;HNRNPC;HNRNPM;HNRNPU;IGF2BP2;LIN28;LIN28B;NOP56;NOP58;PRPF8;SRSF7;TAF15;TARDBP;TNRC6A;TROVE2;U2AF1;U2AF2;UPF1NADendritic_cells_activatedGSVA_HALLMARK_ALLOGRAFT_REJECTION
ENSG00000225733.4,FGD5-AS1
BLCAEAGIRENSG00000111679.12chr126951261:6951520:6951608:6951731-0.32605.2336e-108.9939e-16-0.4262imageNAIFM1;BCCIP;BUD13;CELF2;CPSF6;CSTF2T;DDX3X;DDX54;DHX9;EIF4A3;ELAVL1;EWSR1;FAM120A;FBL;FMR1;FTO;FUS;GTF2F1;HNRNPA1;HNRNPC;HNRNPK;HNRNPM;HNRNPU;HNRNPUL1;IGF2BP1;IGF2BP2;IGF2BP3;ILF3;KHDRBS1;LARP4B;LARP7;LIN28A;LSM11;MSI2;NONO;NOP56;NOP58;PCBP2;PRPF8;PTBP1;PUM2;RANGAP1;RBFOX2;RBM10;SAFB2;SF3A3;SF3B4;SLTM;SND1;SRSF1;SRSF3;SRSF7;SRSF9;TAF15;TARDBP;U2AF1;U2AF2;UPF1;ZNF184PTPN6Dendritic_cells_activatedGSVA_HALLMARK_COMPLEMENT

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5. Enriched editing regions and immune infiltration for FGD5-AS1


all structure

check button Associations of enriched editing regions with immune infiltration.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the fraction of different immune cells according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerTypeIDImmuneCellPRCorrelationPlot
chr3:14944542-14944994:-ACCEERMonocytes3.0342e-03-0.3446image
ENSG00000225733.4,FGD5-AS1ACCEAGMonocytes3.0342e-03-0.3446image
chr3:14944542-14944994:-BLCAEERT_cells_CD4_memory_activated3.3293e-110.3287image
ENSG00000225733.4,FGD5-AS1BLCAEAGT_cells_CD4_memory_activated3.3293e-110.3287image
chr3:14944542-14944994:-BRCAEERT_cells_regulatory_(Tregs)7.9930e-030.0809image
ENSG00000225733.4,FGD5-AS1BRCAEAGT_cells_regulatory_(Tregs)7.9930e-030.0809image
chr3:14944542-14944994:-CESCEERMacrophages_M03.6326e-03-0.1688image
ENSG00000225733.4,FGD5-AS1CESCEAGMacrophages_M03.6326e-03-0.1688image
chr3:14944542-14944994:-CHOLEERB_cells_naive5.1527e-03-0.4625image
ENSG00000225733.4,FGD5-AS1CHOLEAGB_cells_naive5.1527e-03-0.4625image
chr3:14944542-14944994:-COADEERMacrophages_M11.3991e-060.2903image
ENSG00000225733.4,FGD5-AS1COADEAGMacrophages_M11.3991e-060.2903image
ENSG00000225733.4,FGD5-AS1DLBCEAGT_cells_gamma_delta2.0503e-030.4624image
chr3:14944542-14944994:-ESCAEERT_cells_regulatory_(Tregs)2.2334e-02-0.1800image
ENSG00000225733.4,FGD5-AS1ESCAEAGT_cells_regulatory_(Tregs)2.2334e-02-0.1800image
chr3:14944542-14944994:-GBMEERMacrophages_M03.7700e-07-0.3832image
ENSG00000225733.4,FGD5-AS1GBMEAGMacrophages_M03.7700e-07-0.3832image
chr3:14944542-14944994:-HNSCEERT_cells_CD4_memory_activated2.1835e-040.1674image
ENSG00000225733.4,FGD5-AS1HNSCEAGT_cells_CD4_memory_activated2.1835e-040.1674image
chr3:14944542-14944994:-KIRCEERNeutrophils1.1626e-02-0.1290image
ENSG00000225733.4,FGD5-AS1KIRCEAGNeutrophils1.1702e-02-0.1289image
chr3:14944542-14944994:-KIRPEERNK_cells_activated2.5623e-03-0.1786image
ENSG00000225733.4,FGD5-AS1KIRPEAGNK_cells_activated2.5623e-03-0.1786image
chr3:14944542-14944994:-LAMLEERT_cells_CD4_naive4.7892e-030.2397image
ENSG00000225733.4,FGD5-AS1LAMLEAGT_cells_CD4_naive4.7892e-030.2397image
chr3:14944542-14944994:-LGGEERDendritic_cells_activated7.9139e-040.1460image
ENSG00000225733.4,FGD5-AS1LGGEAGDendritic_cells_activated7.9139e-040.1460image
chr3:14944542-14944994:-LIHCEERMacrophages_M11.0039e-030.1729image
ENSG00000225733.4,FGD5-AS1LIHCEAGMacrophages_M11.0039e-030.1729image
chr3:14944542-14944994:-LUADEERT_cells_CD4_naive2.1978e-040.1620image
ENSG00000225733.4,FGD5-AS1LUADEAGT_cells_CD4_naive2.1978e-040.1620image
chr3:14944542-14944994:-LUSCEERMacrophages_M24.3245e-03-0.1283image
ENSG00000225733.4,FGD5-AS1LUSCEAGMacrophages_M24.3245e-03-0.1283image
chr3:14944542-14944994:-MESOEERT_cells_gamma_delta5.5787e-030.3053image
ENSG00000225733.4,FGD5-AS1MESOEAGT_cells_gamma_delta5.5787e-030.3053image
chr3:14944542-14944994:-OVEERMacrophages_M12.3267e-060.2728image
ENSG00000225733.4,FGD5-AS1OVEAGMacrophages_M12.3267e-060.2728image
chr3:14944542-14944994:-PAADEERT_cells_CD83.7146e-020.1568image
ENSG00000225733.4,FGD5-AS1PAADEAGT_cells_CD83.7146e-020.1568image
chr3:14944542-14944994:-PCPGEERT_cells_follicular_helper2.0036e-020.1742image
ENSG00000225733.4,FGD5-AS1PCPGEAGT_cells_follicular_helper1.9635e-020.1748image
chr3:14944542-14944994:-PRADEERDendritic_cells_activated3.9641e-050.1842image
ENSG00000225733.4,FGD5-AS1PRADEAGDendritic_cells_activated3.9641e-050.1842image
chr3:14944542-14944994:-READEERT_cells_CD4_memory_activated6.2336e-04-0.3520image
ENSG00000225733.4,FGD5-AS1READEAGT_cells_CD4_memory_activated6.2336e-04-0.3520image
chr3:14944542-14944994:-SARCEERT_cells_CD84.3343e-030.1791image
ENSG00000225733.4,FGD5-AS1SARCEAGT_cells_CD84.1327e-030.1801image
chr3:14944542-14944994:-SKCMEERT_cells_CD86.6883e-090.2676image
ENSG00000225733.4,FGD5-AS1SKCMEAGT_cells_CD86.6883e-090.2676image
chr3:14944542-14944994:-STADEERMast_cells_activated2.2477e-04-0.1899image
ENSG00000225733.4,FGD5-AS1STADEAGMast_cells_activated2.2477e-04-0.1899image
chr3:14944542-14944994:-TGCTEERNK_cells_activated3.3658e-02-0.1742image
ENSG00000225733.4,FGD5-AS1TGCTEAGNK_cells_activated3.3658e-02-0.1742image
chr3:14944542-14944994:-THCAEEREosinophils1.2325e-04-0.1710image
ENSG00000225733.4,FGD5-AS1THCAEAGEosinophils1.2325e-04-0.1710image
ENSG00000225733.4,FGD5-AS1THYMEAGMast_cells_resting3.3597e-060.4359image
chr3:14944542-14944994:-UCECEERDendritic_cells_activated3.1085e-020.1669image
ENSG00000225733.4,FGD5-AS1UCECEAGDendritic_cells_activated3.1085e-020.1669image
chr3:14944542-14944994:-UCSEERT_cells_CD4_memory_activated3.8963e-050.5426image
ENSG00000225733.4,FGD5-AS1UCSEAGT_cells_CD4_memory_activated3.8963e-050.5426image
chr3:14944542-14944994:-UVMEERT_cells_regulatory_(Tregs)2.5063e-020.2677image
ENSG00000225733.4,FGD5-AS1UVMEAGT_cells_regulatory_(Tregs)2.5063e-020.2677image


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6. Enriched editing regions and immune gene sets for FGD5-AS1


all structure

check button Correlation of enriched editing regions with epithelial-mesenchymal transition.
* First, the differences of enriched editing regions between Epi and Mes groups (defined by KS-test) were compared (P<0.05 and Informative number >=20).
* Second, the correlations between enriched editing regions and gene set score of HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly edited between Epi and Mes group.
ID_eventscancerTypeE2M_PBoxplotCorPCorRCorrelationPlot
chr3:14944542-14944994:-BLCAEER1.1633e-04image1.3392e-090.3019image
ENSG00000225733.4,FGD5-AS1BLCAEAG1.1633e-04image1.3392e-090.3019image
chr3:14944542-14944994:-KIRPEER2.5035e-02image1.1626e-040.2271image
ENSG00000225733.4,FGD5-AS1KIRPEAG2.5035e-02image1.1626e-040.2271image
chr3:14944542-14944994:-STADEER9.8293e-04image8.0439e-040.1728image
ENSG00000225733.4,FGD5-AS1STADEAG9.8293e-04image8.0439e-040.1728image


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check button Correlations of enriched editing regions with hypoxic.
* First, there are four hypoxia scores used in the database. The first three hypoxic scores were calculated on three gene sets of Buffa, Ragnum and Winter based on one previous study (PMID: 32024819). One last hypoxia score was defined on HALLMARK_HYPOXIA by GSVA method.
* Second, the correlations enriched editing regions with the four hypoxic scores were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the EERs/EAGs significantly correlated with all four hypoxia gene set scores. For more results, please go to download page.
ID_eventscancerTypeBuffa_P Buffa_R Ragnum_P Ragnum_R Winter_P Winter_R HALLMARK_P HALLMARK_R CorrelationPlot
chr3:14944542-14944994:-BLCAEER5.6511e-070.25101.4919e-020.12371.1185e-050.22125.0656e-080.2726image
ENSG00000225733.4,FGD5-AS1BLCAEAG5.6511e-070.25101.4919e-020.12371.1185e-050.22125.0656e-080.2726image
chr3:14944542-14944994:-SKCMEER1.8046e-04-0.17475.1344e-06-0.21191.3204e-06-0.22454.0141e-030.1346image
ENSG00000225733.4,FGD5-AS1SKCMEAG1.8046e-04-0.17475.1344e-06-0.21191.3204e-06-0.22454.0141e-030.1346image


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check button Associations of enriched editing regions with hallmark gene sets from MSigDB.
* P<0.05 and Informative number >=20.
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the scores of 50 hallmark genesets according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerHallmarkTypeTypePRCorrelationPlot
chr3:14944542-14944994:-ACCGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEER2.4907e-020.2642image
ENSG00000225733.4,FGD5-AS1ACCGSVA_HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAYEAG2.4907e-020.2642image
ENSG00000225733.4,FGD5-AS1BLCAGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEAG3.6538e-220.4651image
chr3:14944542-14944994:-BLCAGSVA_HALLMARK_INTERFERON_GAMMA_RESPONSEEER3.6538e-220.4651image
ENSG00000225733.4,FGD5-AS1BRCAGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG4.6592e-210.2818image
chr3:14944542-14944994:-BRCAGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER4.6592e-210.2818image
ENSG00000225733.4,FGD5-AS1CESCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG1.9281e-070.2975image
chr3:14944542-14944994:-CESCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.9281e-070.2975image
ENSG00000225733.4,FGD5-AS1CHOLGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEAG1.0302e-020.4281image
chr3:14944542-14944994:-CHOLGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEER1.0302e-020.4281image
chr3:14944542-14944994:-COADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER3.3484e-100.3723image
ENSG00000225733.4,FGD5-AS1COADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG3.3484e-100.3723image
ENSG00000225733.4,FGD5-AS1DLBCGSVA_HALLMARK_G2M_CHECKPOINTEAG1.1487e-03-0.4845image
ENSG00000225733.4,FGD5-AS1ESCAGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG6.2081e-040.2669image
chr3:14944542-14944994:-ESCAGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER6.2081e-040.2669image
chr3:14944542-14944994:-GBMGSVA_HALLMARK_BILE_ACID_METABOLISMEER3.1774e-160.5802image
ENSG00000225733.4,FGD5-AS1GBMGSVA_HALLMARK_BILE_ACID_METABOLISMEAG3.1774e-160.5802image
ENSG00000225733.4,FGD5-AS1HNSCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG5.7600e-170.3683image
chr3:14944542-14944994:-HNSCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER5.7600e-170.3683image
ENSG00000225733.4,FGD5-AS1KICHGSVA_HALLMARK_OXIDATIVE_PHOSPHORYLATIONEAG3.8691e-030.3589image
ENSG00000225733.4,FGD5-AS1KIRCGSVA_HALLMARK_IL2_STAT5_SIGNALINGEAG8.1863e-050.2001image
chr3:14944542-14944994:-KIRCGSVA_HALLMARK_IL2_STAT5_SIGNALINGEER8.2325e-050.2001image
chr3:14944542-14944994:-KIRPGSVA_HALLMARK_COAGULATIONEER5.6320e-100.3579image
ENSG00000225733.4,FGD5-AS1KIRPGSVA_HALLMARK_COAGULATIONEAG5.6320e-100.3579image
chr3:14944542-14944994:-LAMLGSVA_HALLMARK_MYC_TARGETS_V2EER6.0316e-05-0.3358image
ENSG00000225733.4,FGD5-AS1LAMLGSVA_HALLMARK_MYC_TARGETS_V2EAG6.0316e-05-0.3358image
chr3:14944542-14944994:-LGGGSVA_HALLMARK_BILE_ACID_METABOLISMEER1.9554e-210.3986image
ENSG00000225733.4,FGD5-AS1LGGGSVA_HALLMARK_BILE_ACID_METABOLISMEAG1.9554e-210.3986image
ENSG00000225733.4,FGD5-AS1LIHCGSVA_HALLMARK_BILE_ACID_METABOLISMEAG1.1321e-150.4059image
chr3:14944542-14944994:-LIHCGSVA_HALLMARK_BILE_ACID_METABOLISMEER1.1321e-150.4059image
chr3:14944542-14944994:-LUADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.4836e-040.1662image
ENSG00000225733.4,FGD5-AS1LUADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG1.4836e-040.1662image
chr3:14944542-14944994:-LUSCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER5.4546e-090.2589image
ENSG00000225733.4,FGD5-AS1LUSCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG5.4546e-090.2589image
ENSG00000225733.4,FGD5-AS1MESOGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG2.3157e-030.3339image
chr3:14944542-14944994:-MESOGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER2.3157e-030.3339image
ENSG00000225733.4,FGD5-AS1OVGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG3.8631e-190.4919image
chr3:14944542-14944994:-OVGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER3.8631e-190.4919image
ENSG00000225733.4,FGD5-AS1PAADGSVA_HALLMARK_P53_PATHWAYEAG1.0334e-030.2446image
chr3:14944542-14944994:-PAADGSVA_HALLMARK_P53_PATHWAYEER1.0334e-030.2446image
chr3:14944542-14944994:-PCPGGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER6.8139e-030.2021image
ENSG00000225733.4,FGD5-AS1PCPGGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG6.6991e-030.2026image
chr3:14944542-14944994:-PRADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.0877e-120.3136image
ENSG00000225733.4,FGD5-AS1PRADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG1.0877e-120.3136image
chr3:14944542-14944994:-READGSVA_HALLMARK_MYOGENESISEER3.9525e-030.2993image
ENSG00000225733.4,FGD5-AS1READGSVA_HALLMARK_MYOGENESISEAG3.9525e-030.2993image
ENSG00000225733.4,FGD5-AS1SARCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG4.5180e-060.2843image
chr3:14944542-14944994:-SARCGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER3.8021e-060.2864image
chr3:14944542-14944994:-SKCMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER7.2766e-160.3659image
ENSG00000225733.4,FGD5-AS1SKCMGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG7.2766e-160.3659image
ENSG00000225733.4,FGD5-AS1STADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG5.0060e-190.4393image
chr3:14944542-14944994:-STADGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER5.0060e-190.4393image
ENSG00000225733.4,FGD5-AS1TGCTGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG5.6735e-030.2256image
chr3:14944542-14944994:-TGCTGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER5.6735e-030.2256image
chr3:14944542-14944994:-THCAGSVA_HALLMARK_ESTROGEN_RESPONSE_EARLYEER3.0878e-060.2071image
ENSG00000225733.4,FGD5-AS1THCAGSVA_HALLMARK_ESTROGEN_RESPONSE_EARLYEAG3.0878e-060.2071image
ENSG00000225733.4,FGD5-AS1THYMGSVA_HALLMARK_G2M_CHECKPOINTEAG2.7040e-10-0.5677image
chr3:14944542-14944994:-UCECGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEER9.3681e-06-0.3354image
ENSG00000225733.4,FGD5-AS1UCECGSVA_HALLMARK_WNT_BETA_CATENIN_SIGNALINGEAG9.3681e-06-0.3354image
chr3:14944542-14944994:-UCSGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEER1.6410e-020.3346image
ENSG00000225733.4,FGD5-AS1UCSGSVA_HALLMARK_INTERFERON_ALPHA_RESPONSEEAG1.6410e-020.3346image
ENSG00000225733.4,FGD5-AS1UVMGSVA_HALLMARK_KRAS_SIGNALING_DNEAG1.5987e-040.4362image
chr3:14944542-14944994:-UVMGSVA_HALLMARK_KRAS_SIGNALING_DNEER1.5987e-040.4362image


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7. Enriched editing regions and drugs for FGD5-AS1


all structure

check button Correlations between enriched editing regions and drug sensitivity.
* First, the drug sensitivity (IS50) was estimated on 84 drugs by pRRophetic package.
* Second, the correlations between editing enriched regions and drug sensitivity were analyzed (P<0.05 and Informative number >=20).
* EER: enriched editing region, EAG: EER-associated genes.
* Only shows the most significant correlation result of EERs/EAGs with the IS50 scores of 84 drugs according to correlation coefficient (R). For more results, please go to download page.
ID_eventscancerDrugTypePRCorrelationPlot
chr3:14944542-14944994:-ACCABT.263EER2.3115e-030.3536image
ENSG00000225733.4,FGD5-AS1ACCABT.263EAG2.3115e-030.3536image
ENSG00000225733.4,FGD5-AS1BLCACGP.60474EAG2.0959e-16-0.4013image
chr3:14944542-14944994:-BLCACGP.60474EER2.0959e-16-0.4013image
ENSG00000225733.4,FGD5-AS1BRCAAxitinibEAG9.1628e-070.1492image
chr3:14944542-14944994:-BRCAAxitinibEER9.1628e-070.1492image
ENSG00000225733.4,FGD5-AS1CESCCGP.60474EAG1.5156e-04-0.2188image
chr3:14944542-14944994:-CESCCGP.60474EER1.5156e-04-0.2188image
ENSG00000225733.4,FGD5-AS1CHOLBryostatin.1EAG3.6226e-03-0.4787image
chr3:14944542-14944994:-CHOLBryostatin.1EER3.6226e-03-0.4787image
chr3:14944542-14944994:-COADGefitinibEER1.4736e-06-0.2897image
ENSG00000225733.4,FGD5-AS1COADGefitinibEAG1.4736e-06-0.2897image
ENSG00000225733.4,FGD5-AS1DLBCGNF.2EAG1.0316e-04-0.5632image
ENSG00000225733.4,FGD5-AS1ESCAAZD6482EAG1.3549e-04-0.2963image
chr3:14944542-14944994:-ESCAAZD6482EER1.3549e-04-0.2963image
chr3:14944542-14944994:-GBMBMS.754807EER3.2130e-130.5278image
ENSG00000225733.4,FGD5-AS1GBMBMS.754807EAG3.2130e-130.5278image
ENSG00000225733.4,FGD5-AS1HNSCErlotinibEAG2.8592e-11-0.2973image
chr3:14944542-14944994:-HNSCErlotinibEER2.8592e-11-0.2973image
ENSG00000225733.4,FGD5-AS1KICHABT.263EAG1.6052e-040.4580image
ENSG00000225733.4,FGD5-AS1KIRCGemcitabineEAG2.2165e-04-0.1879image
chr3:14944542-14944994:-KIRCGemcitabineEER2.3040e-04-0.1874image
chr3:14944542-14944994:-KIRPBX.795EER5.4267e-07-0.2926image
ENSG00000225733.4,FGD5-AS1KIRPBX.795EAG5.4267e-07-0.2926image
chr3:14944542-14944994:-LAMLEHT.1864EER5.5424e-030.2358image
ENSG00000225733.4,FGD5-AS1LAMLEHT.1864EAG5.5424e-030.2358image
chr3:14944542-14944994:-LGGIPA.3EER6.8210e-350.5022image
ENSG00000225733.4,FGD5-AS1LGGIPA.3EAG6.8210e-350.5022image
ENSG00000225733.4,FGD5-AS1LIHCBleomycinEAG4.7244e-130.3729image
chr3:14944542-14944994:-LIHCBleomycinEER4.7244e-130.3729image
chr3:14944542-14944994:-LUADEmbelinEER6.7723e-04-0.1491image
ENSG00000225733.4,FGD5-AS1LUADEmbelinEAG6.7723e-04-0.1491image
chr3:14944542-14944994:-LUSCCI.1040EER2.4360e-04-0.1645image
ENSG00000225733.4,FGD5-AS1LUSCCI.1040EAG2.4360e-04-0.1645image
ENSG00000225733.4,FGD5-AS1MESOBexaroteneEAG5.1951e-030.3077image
chr3:14944542-14944994:-MESOBexaroteneEER5.1951e-030.3077image
ENSG00000225733.4,FGD5-AS1OVBIBW2992EAG3.9722e-06-0.2667image
chr3:14944542-14944994:-OVBIBW2992EER3.9722e-06-0.2667image
ENSG00000225733.4,FGD5-AS1PAADBexaroteneEAG2.0533e-02-0.1740image
chr3:14944542-14944994:-PAADBexaroteneEER2.0533e-02-0.1740image
chr3:14944542-14944994:-PCPGAxitinibEER3.5764e-030.2173image
ENSG00000225733.4,FGD5-AS1PCPGAxitinibEAG3.5206e-030.2176image
chr3:14944542-14944994:-PRADGW.441756EER2.1766e-120.3096image
ENSG00000225733.4,FGD5-AS1PRADGW.441756EAG2.1766e-120.3096image
chr3:14944542-14944994:-READJNK.9LEER5.8030e-04-0.3538image
ENSG00000225733.4,FGD5-AS1READJNK.9LEAG5.8030e-04-0.3538image
ENSG00000225733.4,FGD5-AS1SARCGefitinibEAG2.0118e-06-0.2942image
chr3:14944542-14944994:-SARCGefitinibEER1.9150e-06-0.2948image
chr3:14944542-14944994:-SKCMGNF.2EER4.3824e-11-0.3025image
ENSG00000225733.4,FGD5-AS1SKCMGNF.2EAG4.3824e-11-0.3025image
ENSG00000225733.4,FGD5-AS1STADBexaroteneEAG6.7157e-07-0.2539image
chr3:14944542-14944994:-STADBexaroteneEER6.7157e-07-0.2539image
ENSG00000225733.4,FGD5-AS1TGCTGW.441756EAG5.3070e-030.2273image
chr3:14944542-14944994:-TGCTGW.441756EER5.3070e-030.2273image
chr3:14944542-14944994:-THCAAMG.706EER1.4979e-050.1925image
ENSG00000225733.4,FGD5-AS1THCAAMG.706EAG1.4979e-050.1925image
ENSG00000225733.4,FGD5-AS1THYMABT.263EAG1.7795e-090.5454image
chr3:14944542-14944994:-UCECCMKEER9.4722e-07-0.3687image
ENSG00000225733.4,FGD5-AS1UCECCMKEAG9.4722e-07-0.3687image
chr3:14944542-14944994:-UCSABT.888EER1.1389e-04-0.5141image
ENSG00000225733.4,FGD5-AS1UCSABT.888EAG1.1389e-04-0.5141image
ENSG00000225733.4,FGD5-AS1UVMLFM.A13EAG5.8374e-04-0.4009image
chr3:14944542-14944994:-UVMLFM.A13EER5.8374e-04-0.4009image


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check button EAGs targeted by drugs from DrugBank database.
* EAG: EER-associated genes.
EERENSTUniprotIDDrugBankIDDrugDrugType